LOCUS       NM_001025705            2017 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus 5-azacytidine induced 2 (Azi2), mRNA.
ACCESSION   NM_001025705 XM_236698
VERSION     NM_001025705.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2017)
  AUTHORS   Maruyama,K., Fukasaka,M., Uematsu,S., Takeuchi,O., Kondo,T.,
            Saitoh,T., Martino,M.M. and Akira,S.
  TITLE     5-Azacytidine-induced protein 2 (AZI2) regulates bone mass by
            fine-tuning osteoclast survival
  JOURNAL   J Biol Chem 290 (15), 9377-9386 (2015)
   PUBMED   25691576
  REMARK    GeneRIF: Data indicate that 5-Azacytidine-induced protein 2 (AZI2)
            deficiency mice Are osteoporotic.
REFERENCE   2  (bases 1 to 2017)
  AUTHORS   Fukasaka,M., Ori,D., Kawagoe,T., Uematsu,S., Maruyama,K.,
            Okazaki,T., Kozaki,T., Imamura,T., Tartey,S., Mino,T., Satoh,T.,
            Akira,S. and Takeuchi,O.
  TITLE     Critical role of AZI2 in GM-CSF-induced dendritic cell
            differentiation
  JOURNAL   J Immunol 190 (11), 5702-5711 (2013)
   PUBMED   23610142
REFERENCE   3  (bases 1 to 2017)
  AUTHORS   Miyagawa,J., Muguruma,M., Aoto,H., Suetake,I., Nakamura,M. and
            Tajima,S.
  TITLE     Isolation of the novel cDNA of a gene of which expression is
            induced by a demethylating stimulus
  JOURNAL   Gene 240 (2), 289-295 (1999)
   PUBMED   10580148
REFERENCE   4  (bases 1 to 2017)
  AUTHORS   Hutchison,J.B., Beyer,C., Green,S. and Wozniak,A.
  TITLE     Brain formation of oestrogen in the mouse: sex dimorphism in
            aromatase development
  JOURNAL   J Steroid Biochem Mol Biol 49 (4-6), 407-415 (1994)
   PUBMED   8043507
  REMARK    Review article
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC098680.1.
            
            On Jul 22, 2005 this sequence version replaced XM_236698.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC098680.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132267, SAMD00132269
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..2017
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="8"
                     /map="8q32"
     gene            1..2017
                     /gene="Azi2"
                     /note="5-azacytidine induced 2"
                     /db_xref="GeneID:316051"
                     /db_xref="RGD:1310530"
     exon            1..360
                     /gene="Azi2"
                     /inference="alignment:Splign:2.1.0"
     exon            361..581
                     /gene="Azi2"
                     /inference="alignment:Splign:2.1.0"
     CDS             366..1580
                     /gene="Azi2"
                     /note="5-azacytidine induced gene 2"
                     /codon_start=1
                     /product="5-azacytidine-induced protein 2"
                     /protein_id="NP_001020876.1"
                     /db_xref="GeneID:316051"
                     /db_xref="RGD:1310530"
                     /translation="MDTLVEDDICILNHEKAHKREAVTPLSAYPGDESVASHFALVTA
                     YEDIKKRLKDSEKENSFLKKRIRALEEKLVGARVEEETSSVGREQVNKAYHAYREVCI
                     DRDNLKSRLEKISKDNSESLRALTEQLQCKEVELLQLRTEVETQQVMRNLNPPSSNWE
                     VEKLSCDLKIHGLEQELELLRKECSDLRTELQKARQTGPSQEDILQDRDVIRPSLPRE
                     EHVPHQGPHHSDHMQHAYWELRREMANLHLVTRVQAELLRQLKTAAAGKACTQVGCVE
                     DLGRDSAKLHLANCTAAYKRHPPLSPHGKATCYAPPSTLPGDRKAFSDKAVLQSWTDN
                     ERLTPNDGADFQEHNSYGRNSLEDNSWVFPSPPKSSETAFGESKSKILPSPNLPPLHY
                     LDQHNQNCLYKS"
     exon            582..707
                     /gene="Azi2"
                     /inference="alignment:Splign:2.1.0"
     exon            708..807
                     /gene="Azi2"
                     /inference="alignment:Splign:2.1.0"
     exon            808..956
                     /gene="Azi2"
                     /inference="alignment:Splign:2.1.0"
     exon            957..1051
                     /gene="Azi2"
                     /inference="alignment:Splign:2.1.0"
     exon            1052..1167
                     /gene="Azi2"
                     /inference="alignment:Splign:2.1.0"
     exon            1168..1997
                     /gene="Azi2"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gctgcggggc gttcctagac ccttctagaa ccctctcggc ctcgccgccc ctgaagaggg
       61 cagcgggcgc cggcggcccc ggagctggcg cgcgagctgc tgggtaacag gcctggccgc
      121 ccctgctccg gtcgtccgtg acctccaggg cccctgactg cgggagccgc ggcggaagac
      181 atgggactcc ctccgtgcac ctgtgacggc caccttgact ggggaagcgg cggcgtcttc
      241 gaggaaaccg gaagcccgtg gtgacccctg gcgacccggt ttgttttcaa ccggcttcca
      301 aacaccgggg aagcgaaacc cggtggcctt ggggaccgcc ctacgtagcc agggttcagg
      361 ctgccatgga cacactggta gaagatgaca tctgcattct gaatcatgag aaggcccaca
      421 aaagagaggc agtgacccca ctctcagcgt atcctggaga tgagtctgtt gcttcccatt
      481 ttgccctggt cactgcttat gaagacatca agaagagact taaggattca gagaaagaaa
      541 actccttctt aaagaaaaga ataagggctt tggaagaaaa gcttgttgga gctcgagtag
      601 aagaagaaac aagttctgtg ggccgagaac aagtgaacaa ggcctaccac gcttaccggg
      661 aggtttgcat cgacagagac aacctgaaga gcagactgga gaagataagt aaagacaact
      721 cggagtcctt gagagcgctg accgagcagc tgcagtgtaa agaagtagag ctcctgcagc
      781 tcagaactga ggtggagacg cagcaggtga tgaggaattt aaatccaccc tcgtccaact
      841 gggaggtgga aaagctaagc tgtgacttga agatccatgg tttggaacaa gagctggaac
      901 tactgaggaa agaatgtagt gacctcagaa cagagctaca gaaagccaga cagacgggtc
      961 catctcagga agacattctg caggacagag atgtcatcag gccgagcttg ccgagggaag
     1021 agcacgttcc acaccagggc cctcaccaca gtgaccacat gcagcacgcg tactgggagc
     1081 tgaggaggga gatggctaac ctacacctgg tgactcgggt gcaagccgag ctgctcagac
     1141 agctgaagac ggcagctgcg ggcaaagcct gtacccaagt gggatgtgtt gaagaccttg
     1201 ggagagacag cgcaaaattg cacttggcaa attgtactgc agcttacaaa agacatcccc
     1261 ctttgtcacc acatggcaaa gctacgtgtt atgctccacc ctccacttta ccaggagata
     1321 ggaaggcttt ctcagacaaa gcagttcttc agtcatggac agacaacgag agactgactc
     1381 ctaatgacgg tgcagacttt caggagcaca actcctacgg gagaaattct ctggaagata
     1441 actcctgggt attcccaagc cctcctaaat caagtgagac agcatttggt gaaagtaaaa
     1501 gcaaaatctt accttcaccc aacctgccac ccctgcatta cctggatcag cacaatcaga
     1561 actgcctgta caaaagttaa tttgacttgg gctttgatcg ggacactaac tcactggttc
     1621 tctcagaccg acagtggact ctgactgacg tcctgtggag ctctccagtg tgtacatctg
     1681 tacagtctgc agcattatgt atgtagttga ttttccagta tgggaacgga acctccgcgg
     1741 ttggaccttt gctaacaatt acaaattttt gcttcttgga acacgaatgg aaatgaaaat
     1801 tttagacatg gtttcataaa ctatgacctg cctaaatatc cagtcattaa ataaaaagca
     1861 gcctttaata taagagaaaa accatgtctg ctggttcaga ttgtatcaag aagcaattga
     1921 gagtgtgact aggttgtgct tctgtaactt cctgatgcat aaagatttga aatatggaat
     1981 aaaagtaggt tatgacaaaa aaaaaaaaaa aaaaaaa
//
