LOCUS       NM_001289800            3815 bp    mRNA    linear   ROD 09-APR-2024
DEFINITION  Rattus norvegicus arginine vasopressin receptor 1B (Avpr1b), mRNA.
ACCESSION   NM_001289800 NM_017205 XM_003751236
VERSION     NM_001289800.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 3815)
  AUTHORS   Komnenov,D., Quaal,H. and Rossi,N.F.
  TITLE     V1a and V1b vasopressin receptors within the paraventricular
            nucleus contribute to hypertension in male rats exposed to chronic
            mild unpredictable stress
  JOURNAL   Am J Physiol Regul Integr Comp Physiol 320 (3), R213-R225 (2021)
   PUBMED   33264070
  REMARK    GeneRIF: V1a and V1b vasopressin receptors within the
            paraventricular nucleus contribute to hypertension in male rats
            exposed to chronic mild unpredictable stress.
REFERENCE   2  (bases 1 to 3815)
  AUTHORS   Savic,B., Martin,A., Mecawi,A.S., Bukumiric,Z.,
            Antunes-Rodrigues,J., Murphy,D., Sarenac,O. and Japundzic-Zigon,N.
  TITLE     Vasopressin and v1br gene expression is increased in the
            hypothalamic pvn of borderline hypertensive rats
  JOURNAL   Hypertens Res 43 (11), 1165-1174 (2020)
   PUBMED   32415179
  REMARK    GeneRIF: Vasopressin and v1br gene expression is increased in the
            hypothalamic pvn of borderline hypertensive rats.
REFERENCE   3  (bases 1 to 3815)
  AUTHORS   Sanchez-Tejada,L., Sanchez-Ortiga,R., Lamas,C., Camara,R.,
            Riesgo,P., Fajardo,C., Aranda,F.I. and Pico,A.
  TITLE     Contribution of molecular analysis to the typification of the
            non-functioning pituitary adenomas
  JOURNAL   PLoS One 12 (7), e0180039 (2017)
   PUBMED   28692683
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 3815)
  AUTHORS   Taveau,C., Chollet,C., Bichet,D.G., Velho,G., Guillon,G.,
            Corbani,M., Roussel,R., Bankir,L., Melander,O. and Bouby,N.
  TITLE     Acute and chronic hyperglycemic effects of vasopressin in normal
            rats: involvement of V1A receptors
  JOURNAL   Am J Physiol Endocrinol Metab 312 (3), E127-E135 (2017)
   PUBMED   27998960
  REMARK    GeneRIF: V1BR receptors are almost exclusively present on
            alpha-glucagon cells in the pancreas.
REFERENCE   5  (bases 1 to 3815)
  AUTHORS   Francis,S.M., Kim,S.J., Kistner-Griffin,E., Guter,S., Cook,E.H. and
            Jacob,S.
  TITLE     ASD and Genetic Associations with Receptors for Oxytocin and
            Vasopressin-AVPR1A, AVPR1B, and OXTR
  JOURNAL   Front Neurosci 10, 516 (2016)
   PUBMED   27920663
  REMARK    Publication Status: Online-Only
REFERENCE   6  (bases 1 to 3815)
  AUTHORS   Nomura,A., Iwasaki,Y., Saito,M., Aoki,Y., Yamamori,E., Ozaki,N.,
            Tachikawa,K., Mutsuga,N., Morishita,M., Yoshida,M., Asai,M.,
            Oiso,Y. and Saito,H.
  TITLE     Involvement of upstream open reading frames in regulation of rat
            V(1b) vasopressin receptor expression
  JOURNAL   Am J Physiol Endocrinol Metab 280 (5), E780-E787 (2001)
   PUBMED   11287361
REFERENCE   7  (bases 1 to 3815)
  AUTHORS   Rabadan-Diehl,C., Lolait,S. and Aguilera,G.
  TITLE     Isolation and characterization of the promoter region of the rat
            vasopressin V1b receptor gene
  JOURNAL   J Neuroendocrinol 12 (5), 437-444 (2000)
   PUBMED   10792583
REFERENCE   8  (bases 1 to 3815)
  AUTHORS   Thibonnier,M., Preston,J.A., Dulin,N., Wilkins,P.L.,
            Berti-Mattera,L.N. and Mattera,R.
  TITLE     The human V3 pituitary vasopressin receptor: ligand binding profile
            and density-dependent signaling pathways
  JOURNAL   Endocrinology 138 (10), 4109-4122 (1997)
   PUBMED   9322919
REFERENCE   9  (bases 1 to 3815)
  AUTHORS   Saito,M., Sugimoto,T., Tahara,A. and Kawashima,H.
  TITLE     Molecular cloning and characterization of rat V1b vasopressin
            receptor: evidence for its expression in extra-pituitary tissues
  JOURNAL   Biochem Biophys Res Commun 212 (3), 751-757 (1995)
   PUBMED   7626108
REFERENCE   10 (bases 1 to 3815)
  AUTHORS   Lolait,S.J., O'Carroll,A.M., Mahan,L.C., Felder,C.C., Button,D.C.,
            Young,W.S. 3rd, Mezey,E. and Brownstein,M.J.
  TITLE     Extrapituitary expression of the rat V1b vasopressin receptor gene
  JOURNAL   Proc Natl Acad Sci U S A 92 (15), 6783-6787 (1995)
   PUBMED   7624319
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000013.1.
            
            On May 16, 2023 this sequence version replaced NM_001289800.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: U27322.1, D45400.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN09345331, SAMN11044071
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1476              JAXUCZ010000013.1  45598763-45600238
            1477-3815           JAXUCZ010000013.1  45608939-45611277
FEATURES             Location/Qualifiers
     source          1..3815
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="13"
                     /map="13q13"
     gene            1..3815
                     /gene="Avpr1b"
                     /gene_synonym="AVPR V1b; AVPR V3; V1bR"
                     /note="arginine vasopressin receptor 1B"
                     /db_xref="GeneID:100909648"
                     /db_xref="RGD:6502812"
     exon            1..1476
                     /gene="Avpr1b"
                     /gene_synonym="AVPR V1b; AVPR V3; V1bR"
                     /inference="alignment:Splign:2.1.0"
     CDS             546..1811
                     /gene="Avpr1b"
                     /gene_synonym="AVPR V1b; AVPR V3; V1bR"
                     /note="vasopressin V3 receptor; antidiuretic hormone
                     receptor 1b"
                     /codon_start=1
                     /product="vasopressin V1b receptor"
                     /protein_id="NP_001276729.1"
                     /db_xref="GeneID:100909648"
                     /db_xref="RGD:6502812"
                     /translation="MNSEPSWTATPSPGGTLPVPNATTPWLGRDEELAKVEIGILATV
                     LVLATGGNLAVLLTLGRHGHKRSRMHLFVLHLALTDLGVALFQVLPQLLWDITYRFQG
                     SDLLCRAVKYLQVLSMFASTYMLLAMTLDRYLAVCHPLRSLRQPSQSTYPLIAAPWLL
                     AAILSLPQVFIFSLREVIQGSGVLDCWADFYFSWGPRAYITWTTMAIFVLPVAVLTAC
                     YGLICHEIYKNLKVKTQAGREERRGWRTWDKSSSSAATRGLPSRVSSISTISRAKIRT
                     VKMTFVIVLAYIACWAPFFSVQMWSVWDENAPNEDSTNVAFTISMLLGNLSSCCNPWI
                     YMGFNSRLLPRSLSHHACCTGSKPQVHRQLSTSSLTSRRTTLLTHACGSPTLRLSLNL
                     SLRAKPRPAGSLKDLEQVDGEATMETSIF"
     exon            1477..3815
                     /gene="Avpr1b"
                     /gene_synonym="AVPR V1b; AVPR V3; V1bR"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 tctgctcctg cctgcgctca ccctctggtg ggagccgaga gcggtgggag cacacggctt
       61 agctgggctt tccaattcct gcaggcgacg cccatggtcc tggacggcac cttcaagaca
      121 acttagggag gtctactctc tccagttcca aaagaaagtt tggacaaagt gaatttgggg
      181 tgcatttggg agatggcagc tgctccctct gcttcctctg tgtcacctct cagaagcccc
      241 tgcctccaac ccactccaac cttcccacac tgacacccag ctcccagtcc ctctttttct
      301 ttctttggtc cctgagcctc tctggggtca gggatgttgg tcctgttccc ttctcctttc
      361 attgtccttt ccatctgtct gctgagctgt ctcacctgtt tctaccttca ccccatcgtc
      421 acccctcacc tcccttctct ccacctctaa acctttctct ctcattccat tttatctatc
      481 aaagttctta cttgcaccca tacctccatc caccttcccc tccttctctc cctgaaattc
      541 taactatgaa ttctgagcct tcttggactg ccaccccctc ccctgggggc accctgcctg
      601 tccccaatgc taccacaccg tggctaggta gggatgaaga gctagccaag gtggagatcg
      661 gtatcctagc tactgtcctg gttctggcca caggaggcaa cctggctgta cttctgactc
      721 tgggccgcca tggccacaag cgctcccgca tgcatctgtt cgtgctgcac ttggccctga
      781 ccgacctggg cgtggcgctt ttccaggtac tgcctcagct gctctgggac atcacctacc
      841 gcttccaggg ctctgacctc ctctgccggg ctgtcaagta tctacaggtg ctcagcatgt
      901 ttgcttccac ttacatgctg ctggccatga cactggaccg gtacctggct gtctgtcacc
      961 ctcttcgaag cctccggcag cccagccagt ctacctaccc tctcattgct gctccctggt
     1021 tgctggctgc catcctcagc ctccctcaag ttttcatttt ttcattgcga gaggtgatcc
     1081 agggctcagg ggtgctggac tgctgggcag atttctactt ttcctggggc ccgcgggcct
     1141 acatcacctg gaccaccatg gctatctttg tgctgccggt ggcggtgctc acagcttgct
     1201 acggcctcat ctgccacgag atctacaaga acctgaaagt caagacccag gctggcaggg
     1261 aggagaggag gggctggcgg acttgggata agtcctcatc ttctgcagcc acgagggggc
     1321 taccttcccg ggtcagcagc atcagtacca tctccagggc aaagatccga accgtgaaga
     1381 tgacctttgt catcgtgctg gcctacattg cttgctgggc acctttcttc agtgtccaga
     1441 tgtggtctgt gtgggatgag aatgccccca atgaagattc taccaatgtg gctttcacca
     1501 tctccatgct tctgggcaac ctcagcagct gctgcaaccc ctggatctac atgggcttca
     1561 acagtcgcct gttgccacgt tccttgagcc accatgcctg ctgcacgggc tctaagcccc
     1621 aagtgcacag gcaactctcc accagcagcc tcactagccg tcgcactacg ctgctgaccc
     1681 atgcctgtgg ttcccctact ctccgactca gccttaacct cagcctccgt gcaaagccca
     1741 gacctgcagg ctcactgaag gatttagagc aggtggacgg ggaagccact atggagacca
     1801 gcatctttta gagaagattc cctggactct ggttctgcac atctcaggca cccggaatgt
     1861 ggactagccg gctcagggat ggtaggaagt ggagcttagt ttgaggcagg gtgaagaggc
     1921 cagaatggct gccattactc tagttgtcaa ggcagtgcct agtgtaggta tgggccactc
     1981 tctctcaatt ttagattgtt ggaaatcaga gcactcaatc ccccattctt gccacattcc
     2041 tggagtacct ataaatatac ccaactggga gatatagtgt tctagatctg ggacagccta
     2101 gatggcactg ccaatgcaga ggctcatctc actacttggt taaccgtcct gattctaacc
     2161 tgactggcac atcgcagtgg aacagggaga ggagagaata gattattaga aagggggatg
     2221 tgtatgtggg acttccatcc atgccaacct gtctatagaa atgaagtggt ctgatggtga
     2281 tgtagaacct gatacctagg agggctgtag taaatgctgt ctctcctcat cagcctcacc
     2341 acaggacagg ttgtctggca atacactgtt cattctcagt tgtgtggttc actgcagttg
     2401 agatagggag aaaggggaga gagaagaagg aataaaaatg gttacagtaa agaccaggaa
     2461 taggagtaag tctgaaaggc acagggccag cgttttctct ccccctcctc ctgtggaccc
     2521 agacttcctg tggggcagtg tggaacagac ttcctttttg aaaaaaaaaa aaaaaaaaga
     2581 caagatggtc atggctctag aaatccttaa agttctagga aaagttggaa tcgaagtttt
     2641 aaatctttgt tctgccctgg gaagccacct ccactttctg ggcctcagcc tcacctgtag
     2701 tgagatggtc tttaaggtct ttctttgctc tggccttcta tggatttgca agactggaat
     2761 tgagtaataa ccccaaaaca ccaagggtgt tctaaccaac gggctcttag aacttttcca
     2821 tttccatgac aatttcatat acacccagcc tcagttctgg taggtcctgt cactgccttg
     2881 gtagcagaag tcacaagaca gagagagaag gggtgaccgc ctcctgcctc gcacctttag
     2941 cactgcccct cccccatgac tgctgctctc ctgtcctctg gtactcaagg gttgggtgta
     3001 ctctgacttg agtcctcctt caaggtagga agagacatcg aggaaaggta aaagctaggg
     3061 ccttgcccac ttcttcctat tatctccagg ggaactcaaa tcttagggga acttctccac
     3121 ctcagttctg gttccaaggg acagccaaaa ttatacaaac agcaccagct agcagcagat
     3181 caggggggct gggtcctgac tctgccctag ctgtgaccac agtcagtaaa accctgagcc
     3241 cgctgtctca gttatgagtc aaagtgggta tcaacgtggt ttgcaatccc tgcagatcta
     3301 caagcttcag agcaaaagtc tcaggaacag gctagctctg cccattccca gggacacttt
     3361 aaagagtggc tacagctttg caaaggtact tcttgggtgc ctattttttt gtcaactcga
     3421 cacagacatg gaggaggtaa catcagttga ggaactgact ccatcagact ggtctgtggg
     3481 gattttcttg attggtgatt gatgtgggag ggcccagccc actgtgggca gtgccaccct
     3541 tggaaaagtg gtcataggtt gtagaaaaaa agagagctga catgaaaatg tacatacaag
     3601 taacaccata cagagtgagc ggtttgttat caggaataca catacacata catgtatgca
     3661 gcaacggtta atgcaaaaag gcaatggctt tgaaaaggag aaggtagggg cgtatagaag
     3721 agtgtggagg gaggaaaggg aaagggagaa acgatgtgat tacactataa cctcaaaaat
     3781 acattatttt aaaaattaga aagaagggaa ggggg
//
