LOCUS       NM_001079899            1451 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus AUP1, lipid droplet regulating VLDL assembly
            factor (Aup1), mRNA.
ACCESSION   NM_001079899 XM_001057104 XM_001072273
VERSION     NM_001079899.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1451)
  AUTHORS   Zhong,Y., Shen,H., Wang,Y., Yang,Y., Yang,P. and Fang,S.
  TITLE     Identification of ERAD components essential for dislocation of the
            null Hong Kong variant of alpha-1-antitrypsin (NHK)
  JOURNAL   Biochem Biophys Res Commun 458 (2), 424-428 (2015)
   PUBMED   25660456
REFERENCE   2  (bases 1 to 1451)
  AUTHORS   Ghosh,D., Lippert,D., Krokhin,O., Cortens,J.P. and Wilkins,J.A.
  TITLE     Defining the membrane proteome of NK cells
  JOURNAL   J Mass Spectrom 45 (1), 1-25 (2010)
   PUBMED   19946888
REFERENCE   3  (bases 1 to 1451)
  AUTHORS   Kang,D., Oh,S., Ahn,S.M., Lee,B.H. and Moon,M.H.
  TITLE     Proteomic analysis of exosomes from human neural stem cells by flow
            field-flow fractionation and nanoflow liquid chromatography-tandem
            mass spectrometry
  JOURNAL   J Proteome Res 7 (8), 3475-3480 (2008)
   PUBMED   18570454
REFERENCE   4  (bases 1 to 1451)
  AUTHORS   Ma,Q., Zhou,L., Shi,H. and Huo,K.
  TITLE     NUMBL interacts with TAB2 and inhibits TNFalpha and
            IL-1beta-induced NF-kappaB activation
  JOURNAL   Cell Signal 20 (6), 1044-1051 (2008)
   PUBMED   18299187
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC127544.1.
            
            On or before Jan 5, 2007 this sequence version replaced
            XM_001057104.1, XM_001072273.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC127544.1, FQ228919.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132261, SAMD00132262
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1451
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="4"
                     /map="4q34"
     gene            1..1451
                     /gene="Aup1"
                     /note="AUP1, lipid droplet regulating VLDL assembly
                     factor"
                     /db_xref="GeneID:680423"
                     /db_xref="RGD:1591777"
     exon            1..94
                     /gene="Aup1"
                     /inference="alignment:Splign:2.1.0"
     CDS             45..1277
                     /gene="Aup1"
                     /note="ancient ubiquitous protein 1"
                     /codon_start=1
                     /product="lipid droplet-regulating VLDL assembly factor
                     AUP1"
                     /protein_id="NP_001073368.1"
                     /db_xref="GeneID:680423"
                     /db_xref="RGD:1591777"
                     /translation="MEPPPAPGPERLFDSHRLPSDGFLLLALLLYAPVGLCLLVLRLF
                     LGLHVFLVSCALPDSVLRRFVVRTMCAVLGLVARQEDSGLRDHRVRVLISNHVTPFDH
                     NIVNLLTTCSTPLLNSPPSFVCWSRGFMEMDRRVELVESLKKFCASTRLPPTPLLLFP
                     EEEATNGREGLLRFSSWPFSIQDVVQPLTLQVQRPLVSVTVSDASWVSELLWSLFVPF
                     TVYQVRWLHPIRRQLGEENEEFALRVQQLVAKELGQIGTRLTPADKAEHMKRQRHPRL
                     RPQSVQSSFPSPPSPSSDVQLTILAQRVKEVLPHVPLNVIQRDLARTGCVDLTITNLL
                     EGAVAFMPEDVTEGSQSLPTASAPKFPSSGLVTPQPTALTFAKSSWARQESLQERKQA
                     LYEYARRRFRERQAQEAE"
     exon            95..232
                     /gene="Aup1"
                     /inference="alignment:Splign:2.1.0"
     exon            233..383
                     /gene="Aup1"
                     /inference="alignment:Splign:2.1.0"
     exon            384..568
                     /gene="Aup1"
                     /inference="alignment:Splign:2.1.0"
     exon            569..641
                     /gene="Aup1"
                     /inference="alignment:Splign:2.1.0"
     exon            642..715
                     /gene="Aup1"
                     /inference="alignment:Splign:2.1.0"
     exon            716..782
                     /gene="Aup1"
                     /inference="alignment:Splign:2.1.0"
     exon            783..885
                     /gene="Aup1"
                     /inference="alignment:Splign:2.1.0"
     exon            886..1005
                     /gene="Aup1"
                     /inference="alignment:Splign:2.1.0"
     exon            1006..1121
                     /gene="Aup1"
                     /inference="alignment:Splign:2.1.0"
     exon            1122..1240
                     /gene="Aup1"
                     /inference="alignment:Splign:2.1.0"
     exon            1241..1425
                     /gene="Aup1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gaagatggcg gcgacagcgg ccccactttc ctgaagcggc tgcgatggaa cctcccccag
       61 ctccggggcc ggagcggctc tttgactcgc accggctccc gagtgacggc ttcctgctgc
      121 tcgcgctatt gctctacgcg ccggtcggcc tctgcctcct ggttctgcga ctcttcctcg
      181 ggctccacgt cttcctggtc agctgtgctc ttcctgacag cgtcctccgc aggttcgtgg
      241 tacgaaccat gtgtgcggta ctggggctcg tggcccgaca ggaggactcc ggactccggg
      301 atcaccgcgt cagggtcctt atttccaacc atgtaacacc ttttgaccac aacatagtca
      361 accttctcac cacctgtagc acccctctac tcaatagtcc ccccagcttt gtatgttggt
      421 ctcggggctt catggagatg gataggcggg tggagttggt ggagtcactc aagaaattct
      481 gtgcttccac gaggcttcca cccacacctt tgctgctctt ccccgaggaa gaggccacca
      541 atggccgaga agggctcctg cgtttcagtt cgtggccatt ttctatccag gatgtggtac
      601 aacctcttac cctacaagtt cagagacccc tggtctctgt gacggtgtca gatgcctcct
      661 gggtctcaga actgctgtgg tcacttttcg tccctttcac ggtgtatcaa gtaaggtggc
      721 ttcatcccat tcgtcgacag ctgggggaag agaatgagga gtttgcactc cgtgtacaac
      781 agctggtggc caaagaattg ggccagatag ggacacggct cacgccagca gacaaagcag
      841 aacacatgaa gcgacagaga caccccagat tacgccccca gtcagtgcag tcttcttttc
      901 cttctcctcc cagcccttct tctgatgtgc aactgaccat tctcgctcaa agagtcaagg
      961 aggttttgcc ccatgtgcca ttgaatgtca tccagagaga cctggctagg actgggtgtg
     1021 tagacttgac catcaccaat ctgcttgagg gggctgtggc tttcatgcct gaagatgtca
     1081 ctgagggatc tcagtccctg cccacagcct ctgccccaaa gttccccagc tctggcctgg
     1141 tgacccctca gcccacagcc ctaacatttg ccaagtcttc ctgggcccgt caggagagcc
     1201 tgcaggagcg caagcaggca ctgtatgaat atgcaagaag gagattcaga gagagacagg
     1261 cccaggaggc tgaatgagcc caaagaaaca ggatggtacc cagagccgca ggacggagac
     1321 tgggggcagc cctcacccag ctaacaacag gccggatgag tgggtggtaa aaagggaggg
     1381 atggggctcc cccaatctca cattaaattc agggttttca ctcaaaaaaa aaaaaaaaaa
     1441 aaaaaaaaaa a
//
