LOCUS       NM_001401111            7410 bp    mRNA    linear   ROD 31-MAR-2024
DEFINITION  Rattus norvegicus ataxin 1 like (Atxn1l), mRNA.
ACCESSION   NM_001401111 XM_008772564
VERSION     NM_001401111.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 7410)
  AUTHORS   Lu,H.C., Tan,Q., Rousseaux,M.W., Wang,W., Kim,J.Y., Richman,R.,
            Wan,Y.W., Yeh,S.Y., Patel,J.M., Liu,X., Lin,T., Lee,Y., Fryer,J.D.,
            Han,J., Chahrour,M., Finnell,R.H., Lei,Y., Zurita-Jimenez,M.E.,
            Ahimaz,P., Anyane-Yeboa,K., Van Maldergem,L., Lehalle,D.,
            Jean-Marcais,N., Mosca-Boidron,A.L., Thevenon,J., Cousin,M.A.,
            Bro,D.E., Lanpher,B.C., Klee,E.W., Alexander,N., Bainbridge,M.N.,
            Orr,H.T., Sillitoe,R.V., Ljungberg,M.C., Liu,Z., Schaaf,C.P. and
            Zoghbi,H.Y.
  TITLE     Disruption of the ATXN1-CIC complex causes a spectrum of
            neurobehavioral phenotypes in mice and humans
  JOURNAL   Nat Genet 49 (4), 527-536 (2017)
   PUBMED   28288114
REFERENCE   2  (bases 1 to 7410)
  AUTHORS   Kahle,J.J., Souroullas,G.P., Yu,P., Zohren,F., Lee,Y., Shaw,C.A.,
            Zoghbi,H.Y. and Goodell,M.A.
  TITLE     Ataxin1L is a regulator of HSC function highlighting the utility of
            cross-tissue comparisons for gene discovery
  JOURNAL   PLoS Genet 9 (3), e1003359 (2013)
   PUBMED   23555280
REFERENCE   3  (bases 1 to 7410)
  AUTHORS   Lee,Y., Fryer,J.D., Kang,H., Crespo-Barreto,J., Bowman,A.B.,
            Gao,Y., Kahle,J.J., Hong,J.S., Kheradmand,F., Orr,H.T.,
            Finegold,M.J. and Zoghbi,H.Y.
  TITLE     ATXN1 protein family and CIC regulate extracellular matrix
            remodeling and lung alveolarization
  JOURNAL   Dev Cell 21 (4), 746-757 (2011)
   PUBMED   22014525
REFERENCE   4  (bases 1 to 7410)
  AUTHORS   Crespo-Barreto,J., Fryer,J.D., Shaw,C.A., Orr,H.T. and Zoghbi,H.Y.
  TITLE     Partial loss of ataxin-1 function contributes to transcriptional
            dysregulation in spinocerebellar ataxia type 1 pathogenesis
  JOURNAL   PLoS Genet 6 (7), e1001021 (2010)
   PUBMED   20628574
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 7410)
  AUTHORS   Florea,L., Di Francesco,V., Miller,J., Turner,R., Yao,A.,
            Harris,M., Walenz,B., Mobarry,C., Merkulov,G.V., Charlab,R.,
            Dew,I., Deng,Z., Istrail,S., Li,P. and Sutton,G.
  TITLE     Gene and alternative splicing annotation with AIR
  JOURNAL   Genome Res 15 (1), 54-66 (2005)
   PUBMED   15632090
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000019.1.
            
            On Feb 2, 2022 this sequence version replaced XM_008772564.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643284.20263.1,
                                           SRR26643429.55938.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN12840105, SAMN16676789
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-148               JAXUCZ010000019.1  54620877-54621024   c
            149-210             JAXUCZ010000019.1  54618454-54618515   c
            211-7410            JAXUCZ010000019.1  54609852-54617051   c
FEATURES             Location/Qualifiers
     source          1..7410
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="19"
                     /map="19q12"
     gene            1..7410
                     /gene="Atxn1l"
                     /gene_synonym="RGD1561758"
                     /note="ataxin 1 like"
                     /db_xref="GeneID:103694328"
                     /db_xref="RGD:9319286"
     exon            1..148
                     /gene="Atxn1l"
                     /gene_synonym="RGD1561758"
                     /inference="alignment:Splign:2.1.0"
     exon            149..210
                     /gene="Atxn1l"
                     /gene_synonym="RGD1561758"
                     /inference="alignment:Splign:2.1.0"
     exon            211..7410
                     /gene="Atxn1l"
                     /gene_synonym="RGD1561758"
                     /inference="alignment:Splign:2.1.0"
     CDS             328..2367
                     /gene="Atxn1l"
                     /gene_synonym="RGD1561758"
                     /note="alanine and glycine-rich protein-like"
                     /codon_start=1
                     /product="ataxin-1-like"
                     /protein_id="NP_001388040.1"
                     /db_xref="GeneID:103694328"
                     /db_xref="RGD:9319286"
                     /translation="MKPVHERSQECLPPKKRDLPVTSCSTNHTPSSDASEWSRGVVVA
                     GQSQTGARVSLGGDGTEAITGLTVDQYGMLYKVAVPPATFSPTGLPSVVNMSPLPPTF
                     NVASSLIQHPGIHYPPVHYAQLPSTSLQFIGSPYSLPYAVPPNFLPNPLLSPSANLAT
                     THLPHFVPYASLLAEEAAPPPQAASPAQSFTKSSSATSPPGQLPHHSNTQPLDLAPGR
                     MPIYYQTSRLPAGYTLHETSTAGASPILTPQEGQSALEAAAANGQRQRERSVRRESEP
                     LDSTSSKGESQGLVPVVECMVDGQLFSGSQTPRVEVAAPTHRGTPDTDLEVQRVVGAL
                     ASQDYRVVAAQRKDEPSPLNLSHHTLDHQGEGRGSARNPTEVVEKNQTRVFYPQSHQE
                     PVKHRPLPKAVVVANGNLVPTGTDPSLLPVGSEILVASSLDMQARATFPDKEPTPPPV
                     TSSHLPSHFMKGAIIQLATGELKRVEDLQTQDFVRSAEVSGGLKIDSSTVVDIQESQW
                     PGFVMLHFVVGEQQSKVSIEVPPEHPFFVYGQGWSSCSPGRTAQLFSLPCHRLQVGDV
                     CISISLQSLNSNSVSQASCAPPGQLGTPRERPERTILGPRDLCDSEGKNQTSGEGSRV
                     GEPSQPEPSAQACWPAPSFQRYSMQGEEARAALLRPSFIPQEVKLSIEGRSNAGK"
ORIGIN      
        1 gggatgcgct taacgccatc tccgggcgcc cggcttgggg ggggccgctg ggtgtggggc
       61 ggctccgggg ccggggatgg cggcggccgc ggtggcggcg gctccgggac gagcgggagg
      121 agtccaggga gctccgtgag atgggccggc tcccaaacca gaggggagga cacttactac
      181 agctgctcag aagcaccacc agaagctcag atgtgggcac cacagccagc agcggagcgg
      241 agtgcaagga agccacagag aagtcatttc tgatgcccga aggaacaagc acactccttc
      301 taggctctgg gaacaccata aagcaatatg aaacctgttc atgagcggag tcaggaatgc
      361 cttccaccaa agaaacgaga cctccctgtg accagctgct ccacaaacca cacaccctcc
      421 agtgatgctt ctgagtggtc ccgaggggtt gtggtggctg ggcagagcca gacaggagcc
      481 agagtcagcc tcgggggtga tggaactgag gccatcactg gtctgacagt agatcagtat
      541 ggcatgctgt acaaggtggc cgtgccacct gccaccttct caccgactgg cctcccatct
      601 gttgtgaaca tgagcccctt accccccaca tttaatgtag catcttcact gattcaacat
      661 ccaggaatcc actatccccc agtccactat gctcagctcc catccacttc actgcagttt
      721 attgggtctc cttacagcct tccttatgct gtgccaccta atttcctacc caatcctctc
      781 ctttctcctt ctgccaacct tgccaccact caccttccac actttgtgcc atatgcctcc
      841 ctcctagcag aagaggctgc tcctccccca caggctgcat ccccagctca gtcatttacc
      901 aagtcctctt cggccacctc cccacccggc cagttgccac atcactcgaa tactcaacca
      961 ctggatcttg ctccaggccg gatgcccatt tattatcaga catccaggct acctgctgga
     1021 tataccttgc atgaaacttc cacagcaggt gccagcccca ttcttacccc tcaggagggc
     1081 cagtctgctc tggaagcagc tgctgccaat ggacagagac aacgagagcg aagtgtaaga
     1141 cgagaaagtg agccccttga ctccaccagc agcaagggtg aaagccaagg actggtgcca
     1201 gtggtagaat gcatggtgga tggacagttg ttttcaggtt ctcagactcc gagagtggag
     1261 gtggcggcgc caacacatcg agggacccca gacaccgacc ttgaggtcca gcgggtagtc
     1321 ggcgctttag cttctcagga ctatcgtgtg gtggcagctc agaggaaaga tgaacccagc
     1381 cctcttaacc tatcccatca tacccttgac catcagggtg agggacgagg gtcagccagg
     1441 aatcctacag aagtggtgga gaaaaatcag acccgtgtat tctaccctca gtcccatcag
     1501 gaaccagtaa aacacagacc tttacccaaa gcagtggttg tagccaatgg caacctggtg
     1561 cccactggaa ctgaccctag cctgctgcct gtgggctcag agatcctggt ggcatcgagt
     1621 ctggacatgc aggccagagc cactttccca gacaaggagc caacgccacc tcccgttacc
     1681 tcctcccact tgccctccca tttcatgaaa ggcgccatca ttcagttggc tacgggggag
     1741 ctgaagcggg tagaggatct ccaaacccag gactttgtgc gtagtgccga agtgagtggg
     1801 gggctgaaga ttgactctag cacagtcgtg gacattcagg agagccagtg gcctggattt
     1861 gttatgctgc atttcgtggt tggtgaacag cagagtaaag tgagcatcga ggtgccccct
     1921 gagcacccct tttttgtata tggccagggt tggtcctcct gcagccctgg gcggactgca
     1981 caactcttct ctctgccctg ccatcggcta caggtgggag atgtctgcat ctctatcagt
     2041 ttacagagct tgaacagtaa ctcagtttct caggccagct gtgctccccc agggcagctg
     2101 ggtacacccc gagaaaggcc tgagaggacg atcttggggc ccagagacct atgtgacagt
     2161 gaggggaaga accagacttc aggagagggt tcccgggtgg gagagccctc ccagcctgag
     2221 cctagtgctc aggcctgctg gccagcccca agcttccaaa gatacagcat gcaaggggag
     2281 gaggcacggg ctgcgctgct ccgcccctct ttcattccgc aggaggtaaa gctgtccatc
     2341 gaagggcgtt ccaatgcagg aaaatgaacc tctttcccac cccaggactg ggctttctcc
     2401 ccagaggtga gcctcaccgt gagcattgag aggatttgca catgccaagc agagagtggc
     2461 tctcttggca gtgagatctg ggggaaatag gcattaagac agcctcccaa agcaggatgt
     2521 gttgctcata accccatggc atcctctcag gatagctcta gagcatgctg agatggggaa
     2581 ttgaaggctt ggagcaagaa agggtaggag tgcacatagg ataagaaaca ttccaaaatc
     2641 agggcctccc tgtttgttcc taccatccct ggctcctgca agggaagaac aggctttggg
     2701 agccgggggc agagggagga agcaaagaaa gagccaaaaa tgatggtcac agcttatagt
     2761 agcaggaaaa ctgttttctt tcttttttcc tgtctccctc ccctcctttg tggtgggagg
     2821 gcaggaggcc caatggttga aaataagagg gttcccaccc agaactcttc ttgtgagaga
     2881 cgtgcacttt aaagggtgat tttgttacag atgtttatgg cggggttggg ggttggggag
     2941 caccatgatc tatggaacta tgcttggtcc tttgcttcta cccgatccca tctcacctca
     3001 ccattccgct ataaggcttt ctagcagttt agggccagga gagagagaga aaccccttta
     3061 agtttgagaa tgaaggactg ccttgccagg aacccattca gggctgtggg gaaaagattt
     3121 gactaagatg atgggactta ggcaaagctt ttgaaaggcc tctaacctaa attcccactc
     3181 agcctgccag gcccgctttg atacttcatt cagtctgtag tagtaacttc aggacctgga
     3241 ggaccttttc ccctgggcac ctatgctcct ccattgtctg tctatgttgt gccttagcgc
     3301 ctacactgcc cctacccttc tgctgcctga cctctgcatg gtgtatgacc tgggcctcat
     3361 gtgtagctgc actgcctttg tccactaaga cctctagttt ttggtgtcta agggtccctg
     3421 gtttccctat tagctataat ttttatattt agaaactcag aatcatggcc tcttccactg
     3481 gcagcagtat agtggagaaa caagaaagaa accatgccct agactggcca tttccactcc
     3541 agtggatttt cttggcctcc tcccgtccaa atccattgcc tctgagcacc tgggcctaag
     3601 ctgtatcctc ccagtgtcag ctctgaaagt ctagaacagt ccttgtaaca tcttagcaga
     3661 tgtttccttg tgtggtggtg gattcttcta gaaagagcat cttctatctt ggttgtattg
     3721 gctaccacct gtcttattcg tccatctccc tccagctgta ggattccact gggtgttagg
     3781 atttaggttc ccctccccca acaactttca agtggttgag taattttttg tgaaggtttt
     3841 ttttgggggg ggaggggtct ttagactctt gaaggcaact cagggtattg tccacccaac
     3901 tatgtagtta gacttctccc agggaatgat tgtggcattt ccttcataga tagacttgga
     3961 ccagccgaga cctggcctgt caccaggagt cctatacttc tgaagtgtga gcaaaactta
     4021 aggcaagtct tgtgatctct cttcacttac ttcctcccca gctgccaaat ggggaaaata
     4081 atcttaccta cctcctgggg gaggggaagg tctgagaatg gagtccttct tagtgttcag
     4141 gtgctaaagg ttattctcct tggggacaga gtgacagaaa ctggctagtt tgctataaat
     4201 cctacattct gtttcgtacc ttgagagcag atacatggtc agtgagcttt tagggcggac
     4261 tcaaaggaag ctgcttgacc tgactgcaag cactgacgtc tctgaccctg tgctgcattg
     4321 gaggtcacat cctttccctt cttttgcccc cattctctgc tgcttctctg gcttgtttcc
     4381 tacagtgggg gcctgtgggg ttgagtcttg aggaattctt gtctcctgtt tcatgaacaa
     4441 cgcattccta ggtattactg catgtgtggg tttctcacaa gaccccttct cagaaggttc
     4501 ctcatggaat ttagtgacat gcactgtaga tgctcaagaa atgtctaccc aggataccac
     4561 tgagcttcct cctcatgggg cagacatgta attggttagt agttgaagtc aaattgctct
     4621 ctgcttgggc tgcctgtagc tgaatccttg gaaaaagaaa tcgttgaggc ccttgacaaa
     4681 ttgggcattg acttttttgc tatggttctt tttcttatcc ctgcttggtt taaaaaaaaa
     4741 aaaaaaagac aactccctta atgtggcgcc atgcatatgt aacttgattt tgcggagagc
     4801 tttttcctga agtatgcacc ctagaaaaga aactgctaat gcttgtcaga gctatggcag
     4861 tacttgaccc tgagtgtgta agaggtggga ctggctttta aagtgagcat tccagtggtt
     4921 agctgtcagc ttttggggat tgggcggttg acaaagatca gcctggtcct ggttaatggt
     4981 aggactttcc caaaacttgg agaaagaact gctatctgag gctatcagaa atacccatgc
     5041 caatatagag ggggaacttg gtaaaagatg atgatcatcc ttaccaagat gagaagtggg
     5101 gaagggcttc gggtccttag agctgagagc ttctacccaa tagagaagcc caagaagagc
     5161 tagactgacc cctttacact tacggtccca cttggtctta acactatggg ctttgtttgc
     5221 tttgtgctgc tttgccacgg ctgttgtctg ctcactgtcc tgcctgttgc tcattatagc
     5281 tcctgttcct catgtctctg gccatgtaga ctctcaggca ttctgtccag tgttcacctg
     5341 tgttccgcca gtatgactgc acaacacagt catattcaac agtgaaggtg tgaatgctgt
     5401 tgatgggctg ggaaattgga aaggatgcgg cttcagtgct ctcaggaacc cttaggctcc
     5461 aaaaatttgc ctgccttgag agaaaaacaa acaggtcttt tctctcccct ttatggtact
     5521 tctcagaaca agaggaacca agttagggct tgagccagcg tcccagtgca tttgtccagc
     5581 cccagattct gggactaaga aagtgaggtt tggctgaaag agctcaggtt gggcttcatt
     5641 tcattttcac cagtgggtgt tataggcctt ctaaaaacag aatggtaaca taattcaacc
     5701 tgcattgagc cgggattttg aagagttgag tggtcacact ggtgtgaact gaagatggac
     5761 attgggaaag gctcaagcca ttgggataaa gataaccaga ttgatccatt ggctatggga
     5821 acttaggcca caggtttagt tagaatcaag caggataaag gccatgtttt agagatgggt
     5881 taacttccta gaactaagtt tactaaacta cactgaagct attatacttt ctagatcaga
     5941 aaaaatacac tacagttgaa gagctgaatt ctattatgga tggatggatg ttgtgagccc
     6001 ctgcttagaa gccttcacct tctagctccc tggggtagga aaggtccccg catcatgcaa
     6061 taataaaata agcatccgag tctttgcagc tgtcagttgt tttttcaact ctaggatcca
     6121 tctttggacc aaaagtctgg tctgggccta ggatgacatt ggcccttgat gctagagttg
     6181 gctgcattct ctccttccct gcagactatg cacagttccc ggagcagagg gagaggtggt
     6241 gtggcttgcc ctgctgagcc ttctcagcag gaataatagt aataaatgca cttttcacac
     6301 taaaggtttc gttgttagtt ctcctgttaa gcccagatct ttccctagta gattgcagct
     6361 caacagtctg tgatcccaaa gccattccac tgtaaatgcc tggcaggaaa gatggcccca
     6421 gactgggttc ctgcctgcag tgtgtgtggc agtagcccat gtgcctttac ctaatgtcag
     6481 atttgcaagc gtttagtctg tctttatgtt gggggggtct taggtacttc agagagagaa
     6541 ctggtaacag tgattttatg cccaccccac cccctgccag ggactttgct cgtacttgta
     6601 aatggtgagg gttggtgagc tgctggtatt gctgaaggca gggcggaccc ctcacttgct
     6661 catagtgcac tcactgaatt ggattgggga agagactgac tgtactcacg gctaacttga
     6721 agtattaaaa caaggctatc ctctacacac ttcctagtca cgcaggatcc ctgtagccaa
     6781 aacagtatat gttccagctg cgagagcaaa ctgctctcag cttgcatagc accttagggg
     6841 agggaagata atggataggt aatcgggtgg aggaaggatg gtaattttgt catccaggtg
     6901 gctttagggt cctaaggagt agagaagaat ggcactgggg aggtctggat ggatctggtt
     6961 tgtgtaggag ttcctgtaga taaattactg gtccccccaa ccactatccc cagtatgtaa
     7021 tggctgaatt aatatgtaat caactgcatt gtatctaaag ccttagaact agtcaggtgc
     7081 tcctcccacc caataccgtt tcttaccctc taatcctacc tgatctttaa caaagcatta
     7141 ataattctaa ggataatctc tattttgttg tgcttttttg taactgtttt aaataaatca
     7201 atttgtactg tatatttgta cttttgtgag atcctttttg ctgttttacc attttaagtc
     7261 tctgtacttg gctacacaca gattgtattt ttattgttaa tgctctcttc ttatggatac
     7321 ctgcatttaa cttgtggact atgtaaacac aatatatatc aatatctata tatctatata
     7381 tcgatctata taaactacta gcttttcctt
//
