LOCUS       NM_001109178            1378 bp    mRNA    linear   ROD 04-DEC-2024
DEFINITION  Rattus norvegicus ATP synthase c subunit lysine N-methyltransferase
            (Atpsckmt), mRNA.
ACCESSION   NM_001109178 XM_001066063 XM_574885
VERSION     NM_001109178.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1378)
  AUTHORS   Malecki,J.M., Willemen,H.L.D.M., Pinto,R., Ho,A.Y.Y., Moen,A.,
            Kjonstad,I.F., Burgering,B.M.T., Zwartkruis,F., Eijkelkamp,N. and
            Falnes,P.O.
  TITLE     Lysine methylation by the mitochondrial methyltransferase FAM173B
            optimizes the function of mitochondrial ATP synthase
  JOURNAL   J Biol Chem 294 (4), 1128-1141 (2019)
   PUBMED   30530489
REFERENCE   2  (bases 1 to 1378)
  AUTHORS   Willemen,H.L.D.M., Kavelaars,A., Prado,J., Maas,M., Versteeg,S.,
            Nellissen,L.J.J., Tromp,J., Gonzalez Cano,R., Zhou,W.,
            Jakobsson,M.E., Malecki,J., Posthuma,G., Habib,A.M., Heijnen,C.J.,
            Falnes,P.O. and Eijkelkamp,N.
  TITLE     Identification of FAM173B as a protein methyltransferase promoting
            chronic pain
  JOURNAL   PLoS Biol 16 (2), e2003452 (2018)
   PUBMED   29444090
  REMARK    Publication Status: Online-Only
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH473992.1.
            
            On or before Oct 4, 2007 this sequence version replaced
            XM_001066063.1, XM_574885.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: FM117572.1, SRR8487226.24413.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132261, SAMD00132262
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1378
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="2"
                     /map="2q23"
     gene            1..1378
                     /gene="Atpsckmt"
                     /gene_synonym="Fam173b; RGD1560629"
                     /note="ATP synthase c subunit lysine N-methyltransferase"
                     /db_xref="GeneID:499561"
                     /db_xref="RGD:1560629"
     exon            1..222
                     /gene="Atpsckmt"
                     /gene_synonym="Fam173b; RGD1560629"
                     /inference="alignment:Splign:2.1.0"
     CDS             210..860
                     /gene="Atpsckmt"
                     /gene_synonym="Fam173b; RGD1560629"
                     /note="family with sequence similarity 173, member B;
                     protein N-lysine methyltransferase FAM173B; protein
                     FAM173B"
                     /codon_start=1
                     /product="ATP synthase subunit C lysine
                     N-methyltransferase"
                     /protein_id="NP_001102648.1"
                     /db_xref="GeneID:499561"
                     /db_xref="RGD:1560629"
                     /translation="MERGETPEEERQSGCVLPTSPESDSLKTSNWGFLITGVIGGALV
                     TVYAVTTPFIAPALRKVCLPFVPATSRQVENVVKMLQHRRGPLVDIGSGDGRIVIAAA
                     KAGFPAVGYELNPWLVWYSRYRAWREGVHGSAKFYISDLWKVTFAQYSNVVIFGVPQM
                     MPQLEKKLEFELEDGARVIACRFPFPHWTPDHTTGEGIDTVWAYDMSACRTQGKRA"
     exon            223..500
                     /gene="Atpsckmt"
                     /gene_synonym="Fam173b; RGD1560629"
                     /inference="alignment:Splign:2.1.0"
     exon            501..638
                     /gene="Atpsckmt"
                     /gene_synonym="Fam173b; RGD1560629"
                     /inference="alignment:Splign:2.1.0"
     exon            639..689
                     /gene="Atpsckmt"
                     /gene_synonym="Fam173b; RGD1560629"
                     /inference="alignment:Splign:2.1.0"
     exon            690..1378
                     /gene="Atpsckmt"
                     /gene_synonym="Fam173b; RGD1560629"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ccaaacttag aaggcagcgt ctagaacaca aatgcaaata ctagacctaa tccagtcacc
       61 gattcaagga tttgggtttt gaatttttct gaatgcagag ttgcagcggg gagctaattt
      121 ccttaagaca tttttctttt cctttattgc caccccgcct ctgagacgtt ggtagattcc
      181 acttccggtc tccccggaaa tttcgcgcga tggaaagagg agaaacgcct gaggaagaaa
      241 ggcagtcggg atgtgttctt cctacaagtc cggaatctga cagtttgaag acaagcaatt
      301 gggggttctt gattactggg gtcattggtg gtgccctggt gacagtgtat gctgtgacta
      361 cgccatttat cgctccagcc ctccggaaag tttgtttacc atttgtacct gcaacttcga
      421 ggcaggttga aaatgttgtc aagatgttgc aacacagaag aggacctctg gtggacattg
      481 gcagtggtga tggacggatt gtgattgcag ctgcaaaggc aggcttccca gccgtcgggt
      541 atgaactgaa tccgtggctg gtttggtact ccagataccg tgcttggagg gaaggcgtgc
      601 atggctctgc caagttttac atttcagatc tatggaaggt cacctttgca cagtactcga
      661 atgtcgttat ttttggtgtg ccccagatga tgccacagct ggagaagaaa cttgagtttg
      721 aacttgagga tggtgctaga gttattgcct gtcggttccc tttcccacac tggactccag
      781 accacaccac tggagagggt atcgacactg tgtgggccta cgacatgagt gcttgtagaa
      841 cacaaggaaa gagggcctga ttgtgatcag ctcggccagt agaacttggc agagacagtg
      901 gactgtgggc ttcctcatct gagacgcaga gccagctcct tgacactgaa tgacaagtca
      961 ccgctgctct ccttgagaaa atgaacagaa gctcagagaa acatttaagt ttaaactctg
     1021 ctgcttttta aagggcagtt tcacacagcc tgggttggcc ttgagtttgc tgatgacctt
     1081 gaacttctga tccttccact tttacctccc cagtaaaatg tgcttttagt ggaacattct
     1141 ggatgggctc actacctttg catatactag ggtgcatgaa cataaaagta agtgacagtc
     1201 tgtgggtaag aagactgtca tctcagcagc atggtttgat ggcttgggtg aagaggacgg
     1261 ggcacttatg caaacatctg catttcctgt agttttgttc atgactgaga tttatctcct
     1321 ttgtgtagtt tgcagttaaa ttaattttct gtaagattca gagagtgaca tttagatt
//
