LOCUS       NM_001002253             862 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus ATPase, H+ transporting V0 subunit e2 (Atp6v0e2),
            mRNA.
ACCESSION   NM_001002253
VERSION     NM_001002253.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 862)
  AUTHORS   Abbas,Y.M., Wu,D., Bueler,S.A., Robinson,C.V. and Rubinstein,J.L.
  TITLE     Structure of V-ATPase from the mammalian brain
  JOURNAL   Science 367 (6483), 1240-1246 (2020)
   PUBMED   32165585
REFERENCE   2  (bases 1 to 862)
  AUTHORS   Blake-Palmer,K.G., Su,Y., Smith,A.N. and Karet,F.E.
  TITLE     Molecular cloning and characterization of a novel form of the human
            vacuolar H+-ATPase e-subunit: an essential proton pump component
  JOURNAL   Gene 393 (1-2), 94-100 (2007)
   PUBMED   17350184
REFERENCE   3  (bases 1 to 862)
  AUTHORS   Ueda,T., Ugawa,S. and Shimada,S.
  TITLE     A novel putative M9.2 isoform of V-ATPase expressed in the nervous
            system
  JOURNAL   Neuroreport 14 (1), 25-30 (2003)
   PUBMED   12544825
  REMARK    GeneRIF: A cDNA encoding a novel putative neuron-specific isoform
            of vacuolar proton-translocating ATPase (V-ATPase), NM9.2, was
            isolated from rat and mouse.
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            CB566985.1, CB757317.1 and CB584357.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: CB726201.1, FQ212015.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132261, SAMD00132262
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-197               CB566985.1         24-220
            198-427             CB757317.1         182-411
            428-862             CB584357.1         160-594
FEATURES             Location/Qualifiers
     source          1..862
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="4"
                     /map="4q24"
     gene            1..862
                     /gene="Atp6v0e2"
                     /gene_synonym="NM9.2"
                     /note="ATPase, H+ transporting V0 subunit e2"
                     /db_xref="GeneID:436582"
                     /db_xref="RGD:1303238"
     exon            1..176
                     /gene="Atp6v0e2"
                     /gene_synonym="NM9.2"
                     /inference="alignment:Splign:2.1.0"
     CDS             73..318
                     /gene="Atp6v0e2"
                     /gene_synonym="NM9.2"
                     /note="V-ATPase subunit e 2; vacuolar proton pump subunit
                     e 2; ATPase, H+ transporting, V0 subunit E; ATPase, H+
                     transporting, lysosomal V0 subunit E2"
                     /codon_start=1
                     /product="V-type proton ATPase subunit e 2"
                     /protein_id="NP_001002253.1"
                     /db_xref="GeneID:436582"
                     /db_xref="RGD:1303238"
                     /translation="MTAHSFALPVIIFTTFWGLIGIAGPWFVPKGPNRGVIITMLVAT
                     AVCCYLFWLIAILAQLNPLFGPQLKNETIWYVRFLWE"
     exon            177..224
                     /gene="Atp6v0e2"
                     /gene_synonym="NM9.2"
                     /inference="alignment:Splign:2.1.0"
     exon            225..352
                     /gene="Atp6v0e2"
                     /gene_synonym="NM9.2"
                     /inference="alignment:Splign:2.1.0"
     exon            353..862
                     /gene="Atp6v0e2"
                     /gene_synonym="NM9.2"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gcccggacgt gcacctgctt agagagtcct ccgttcgatc cggtaccccg tctgagcatc
       61 gtgcacccag ccatgacagc ccattccttt gcccttcctg tcatcatctt caccacattc
      121 tggggcctca tcggcatcgc tgggccctgg ttcgtgccca aaggacccaa ccgtggggtg
      181 atcatcacca tgctggtagc tactgctgtc tgctgttacc tcttctggct catcgccatc
      241 ttggcccagc tgaaccccct atttgggcca cagctgaaga atgagaccat ctggtacgtg
      301 cgcttcctgt gggagtgacc actgggagtg accggctggc ttctggcccc agatgccctg
      361 ctgtgaaaga tgacccagcc ttgatgtccc tggagaccct gcattcccac tggccccacc
      421 catcagtatg acgttctgtg ctctccgtgc cagcgtgctg tgggatccat accccccaga
      481 gccaacctgg tttcagtttc ccctgtgttc ccagccatta gggggcctcc attttgggaa
      541 aaccctgtgc ttagtcagga cacagtgggg gctaacctga gctcaaatcc ccacacttgg
      601 cacttctctc tcttccaagc agatcctggc tgagaagctg gacctgctgg gatctgtttt
      661 catccaggga gcagaaggca ggactcagcc tggtcccaga aaggactcaa gtctttgtgg
      721 agaagggaca tgtggcccag aacactccaa gcttttcaac tcttgcctcc actgtgttga
      781 aatattgggt cagggtcaca ggcctcctcc agccctgaag tggattaccc atttagtttc
      841 ttgcacttct agatgtgaaa tt
//
