LOCUS       NM_019383                626 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus ATP synthase peripheral stalk subunit d (Atp5pd),
            mRNA; nuclear gene for mitochondrial product.
ACCESSION   NM_019383
VERSION     NM_019383.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 626)
  AUTHORS   Zhu,C., Zhang,W., Liu,J., Mu,B., Zhang,F., Lai,N., Zhou,J., Xu,A.
            and Li,Y.
  TITLE     Marine collagen peptides reduce endothelial cell injury in diabetic
            rats by inhibiting apoptosis and the expression of coupling factor
            6 and microparticles
  JOURNAL   Mol Med Rep 16 (4), 3947-3957 (2017)
   PUBMED   28731155
REFERENCE   2  (bases 1 to 626)
  AUTHORS   Li,N., Yin,J., Cai,W., Liu,J., Zhang,N., Yan,S., Song,L. and Li,X.
  TITLE     Coupling Factor 6 Is Upregulated in Monocrotaline-induced Pulmonary
            Arterial Hypertension in Rats
  JOURNAL   Am J Med Sci 352 (6), 631-636 (2016)
   PUBMED   27916219
REFERENCE   3  (bases 1 to 626)
  AUTHORS   Zhao,C.H., Li,G.H., Wang,Q., Zhao,B. and Wang,Z.B.
  TITLE     Mechanisms of propofol attenuation of ketamine-induced neonatal
            brain injury
  JOURNAL   Eur Rev Med Pharmacol Sci 20 (1), 133-137 (2016)
   PUBMED   26813465
REFERENCE   4  (bases 1 to 626)
  AUTHORS   Walker,M., Caldwell,R.W., Yoon,Y., Nguyen,T.T. and Johnson,J.A.
  TITLE     deltaPKC interaction with the d subunit of F1Fo ATP synthase
            impairs energetics and exacerbates ischemia/reperfusion injury in
            isolated rat hearts
  JOURNAL   J Mol Cell Cardiol 89 (Pt B), 232-240 (2015)
   PUBMED   26519110
  REMARK    GeneRIF: the deltaPKC-dF1Fo inhibitor attenuated
            co-immunoprecipitation of deltaPKC with dF1Fo.
REFERENCE   5  (bases 1 to 626)
  AUTHORS   Ge,L., Zhu,M.M., Yang,J.Y., Wang,F., Zhang,R., Zhang,J.H., Shen,J.,
            Tian,H.F. and Wu,C.F.
  TITLE     Differential proteomic analysis of the anti-depressive effects of
            oleamide in a rat chronic mild stress model of depression
  JOURNAL   Pharmacol Biochem Behav 131, 77-86 (2015)
   PUBMED   25641667
REFERENCE   6  (bases 1 to 626)
  AUTHORS   Aggeler,R., Coons,J., Taylor,S.W., Ghosh,S.S., Garcia,J.J.,
            Capaldi,R.A. and Marusich,M.F.
  TITLE     A functionally active human F1F0 ATPase can be purified by
            immunocapture from heart tissue and fibroblast cell lines. Subunit
            structure and activity studies
  JOURNAL   J Biol Chem 277 (37), 33906-33912 (2002)
   PUBMED   12110673
REFERENCE   7  (bases 1 to 626)
  AUTHORS   Ko,Y.H., Hullihen,J., Hong,S. and Pedersen,P.L.
  TITLE     Mitochondrial F(0)F(1) ATP synthase. Subunit regions on the F1
            motor shielded by F(0), Functional significance, and evidence for
            an involvement of the unique F(0) subunit F(6)
  JOURNAL   J Biol Chem 275 (42), 32931-32939 (2000)
   PUBMED   10887193
REFERENCE   8  (bases 1 to 626)
  AUTHORS   Higuti,T., Kuroiwa,K., Miyazaki,S., Yoshihara,Y., Toda,H.,
            Kakuno,T. and Sakiyama,F.
  TITLE     The complete amino acid sequence of subunit d of rat liver
            mitochondrial H(+)-ATP synthase
  JOURNAL   J Biochem 114 (5), 714-717 (1993)
   PUBMED   7509337
REFERENCE   9  (bases 1 to 626)
  AUTHORS   Higuti,T., Yoshihara,Y., Kuroiwa,K., Kawamura,Y., Toda,H. and
            Sakiyama,F.
  TITLE     A simple, rapid method for purification of epsilon-subunit,
            coupling factor 6, subunit d, and subunit e from rat liver H(+)-ATP
            synthase and determination of the complete amino acid sequence of
            epsilon-subunit
  JOURNAL   J Biol Chem 267 (31), 22658-22661 (1992)
   PUBMED   1429613
REFERENCE   10 (bases 1 to 626)
  AUTHORS   Motojima,K. and Imanaka,T.
  TITLE     cDNA cloning for and preparation of antibodies against subunit d of
            H(+)-ATP synthase in rat mitochondria
  JOURNAL   Biochem Biophys Res Commun 182 (3), 1130-1138 (1992)
   PUBMED   1531750
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from BC059139.1 and BC078846.1.
            
            On Nov 23, 2005 this sequence version replaced NM_019383.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: FQ216885.1, CD373408.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760400
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            gene product(s) localized to mito. :: inferred from homology
            RefSeq Select criteria             :: based on conservation,
                                                  expression, longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-594               BC059139.1         5-598
            595-626             BC078846.1         547-578
FEATURES             Location/Qualifiers
     source          1..626
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="10"
                     /map="10q32.1"
     gene            1..626
                     /gene="Atp5pd"
                     /gene_synonym="Atp5h; Atp5jd; Atpq"
                     /note="ATP synthase peripheral stalk subunit d"
                     /db_xref="GeneID:641434"
                     /db_xref="RGD:620083"
     exon            1..44
                     /gene="Atp5pd"
                     /gene_synonym="Atp5h; Atp5jd; Atpq"
                     /inference="alignment:Splign:2.1.0"
     exon            45..174
                     /gene="Atp5pd"
                     /gene_synonym="Atp5h; Atp5jd; Atpq"
                     /inference="alignment:Splign:2.1.0"
     CDS             53..538
                     /gene="Atp5pd"
                     /gene_synonym="Atp5h; Atp5jd; Atpq"
                     /EC_number="3.6.1.14"
                     /note="ATPase subunit d; ATP synthase, H+ transporting,
                     mitochondrial F0 complex, subunit d; ATP synthase, H+
                     transporting, mitochondrial Fo complex, subunit d"
                     /codon_start=1
                     /product="ATP synthase subunit d, mitochondrial"
                     /protein_id="NP_062256.1"
                     /db_xref="GeneID:641434"
                     /db_xref="RGD:620083"
                     /translation="MAGRKLALKTIDWVSFVEIMPQNQKAIGNALKSWNETFHTRLAS
                     LSEKPPAIDWAYYRANVDKPGLVDDFKNKYNALKIPVPEDKYTALVDAEEKEDVKNCA
                     QFVTGSQARVREYEKQLEKIKNMIPFDQMTIDDLNEVFPETKLDKRKYPYWPHQPIEN
                     L"
     exon            175..271
                     /gene="Atp5pd"
                     /gene_synonym="Atp5h; Atp5jd; Atpq"
                     /inference="alignment:Splign:2.1.0"
     exon            272..343
                     /gene="Atp5pd"
                     /gene_synonym="Atp5h; Atp5jd; Atpq"
                     /inference="alignment:Splign:2.1.0"
     exon            344..406
                     /gene="Atp5pd"
                     /gene_synonym="Atp5h; Atp5jd; Atpq"
                     /inference="alignment:Splign:2.1.0"
     exon            407..601
                     /gene="Atp5pd"
                     /gene_synonym="Atp5h; Atp5jd; Atpq"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gttcctttct gctggagaca gcgctccgcc gggggtcggt gaagtatcca agatggctgg
       61 gcgcaaactt gctctaaaaa ccatcgattg ggtatctttt gtggagatca tgccccaaaa
      121 ccagaaggca attggaaacg ctctgaagtc ctggaatgag accttccaca ccaggttggc
      181 tagtctgtct gagaaaccac cagcgattga ctgggcttac tacagggcca atgtggacaa
      241 gcctggcttg gtggatgatt ttaaaaacaa gtataatgct ctgaagatcc ctgtgcctga
      301 ggataaatac acagccctag tggacgccga ggagaaggag gatgtgaaga actgtgccca
      361 gttcgtgact ggatctcagg ctagggtccg ggaatatgag aagcagctgg agaaaataaa
      421 gaacatgatt ccctttgacc agatgacgat tgatgacttg aatgaggtct tccctgaaac
      481 caagctggac aagaggaagt acccatactg gccccatcag cccatcgaga acctgtgaag
      541 cagcccagga gggagccctg gctgacttga aataaaacat ttacatagtc ttgctatggt
      601 caaaaaaaaa aaaaaaaaaa aaaaaa
//
