LOCUS       NM_133544                313 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus ATP synthase membrane subunit K (Atp5mk), mRNA;
            nuclear gene for mitochondrial product.
ACCESSION   NM_133544 XM_346587
VERSION     NM_133544.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 313)
  AUTHORS   Barca,E., Ganetzky,R.D., Potluri,P., Juanola-Falgarona,M., Gai,X.,
            Li,D., Jalas,C., Hirsch,Y., Emmanuele,V., Tadesse,S., Ziosi,M.,
            Akman,H.O., Chung,W.K., Tanji,K., McCormick,E.M., Place,E.,
            Consugar,M., Pierce,E.A., Hakonarson,H., Wallace,D.C., Hirano,M.
            and Falk,M.J.
  TITLE     USMG5 Ashkenazi Jewish founder mutation impairs mitochondrial
            complex V dimerization and ATP synthesis
  JOURNAL   Hum Mol Genet 27 (19), 3305-3312 (2018)
   PUBMED   29917077
REFERENCE   2  (bases 1 to 313)
  AUTHORS   Kontro,H., Hulmi,J.J., Rahkila,P. and Kainulainen,H.
  TITLE     Cellular and tissue expression of DAPIT, a phylogenetically
            conserved peptide
  JOURNAL   Eur J Histochem 56 (2), e18 (2012)
   PUBMED   22688299
  REMARK    GeneRIF: confirm the mitochondrial presence of DAPIT on cellular
            level. We also show that DAPIT is localized in lysosomes of HUVEC
            and HEK 293T cells
            Publication Status: Online-Only
REFERENCE   3  (bases 1 to 313)
  AUTHORS   Meyer,B., Wittig,I., Trifilieff,E., Karas,M. and Schagger,H.
  TITLE     Identification of two proteins associated with mammalian ATP
            synthase
  JOURNAL   Mol Cell Proteomics 6 (10), 1690-1699 (2007)
   PUBMED   17575325
REFERENCE   4  (bases 1 to 313)
  AUTHORS   Chen,R., Runswick,M.J., Carroll,J., Fearnley,I.M. and Walker,J.E.
  TITLE     Association of two proteolipids of unknown function with ATP
            synthase from bovine heart mitochondria
  JOURNAL   FEBS Lett 581 (17), 3145-3148 (2007)
   PUBMED   17570365
REFERENCE   5  (bases 1 to 313)
  AUTHORS   Mootha,V.K., Bunkenborg,J., Olsen,J.V., Hjerrild,M.,
            Wisniewski,J.R., Stahl,E., Bolouri,M.S., Ray,H.N., Sihag,S.,
            Kamal,M., Patterson,N., Lander,E.S. and Mann,M.
  TITLE     Integrated analysis of protein composition, tissue diversity, and
            gene regulation in mouse mitochondria
  JOURNAL   Cell 115 (5), 629-640 (2003)
   PUBMED   14651853
REFERENCE   6  (bases 1 to 313)
  AUTHORS   Da Cruz,S., Xenarios,I., Langridge,J., Vilbois,F., Parone,P.A. and
            Martinou,J.C.
  TITLE     Proteomic analysis of the mouse liver mitochondrial inner membrane
  JOURNAL   J Biol Chem 278 (42), 41566-41571 (2003)
   PUBMED   12865426
REFERENCE   7  (bases 1 to 313)
  AUTHORS   Paivarinne,H. and Kainulainen,H.
  TITLE     DAPIT, a novel protein down-regulated in insulin-sensitive tissues
            in streptozotocin-induced diabetes
  JOURNAL   Acta Diabetol 38 (2), 83-86 (2001)
   PUBMED   11757806
  REMARK    GeneRIF: down-regulated in insulin-sensitive tissues (skeletal
            muscle, myocardium)in streptozotocin-induced diabetes
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from
            JAXUCZ010000001.1.
            
            On Nov 26, 2020 this sequence version replaced NM_133544.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AJ271158.1, FQ217783.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN16676785, SAMN16676787
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-18                JAXUCZ010000001.1  255922030-255922047 c
            19-114              JAXUCZ010000001.1  255918050-255918145 c
            115-207             JAXUCZ010000001.1  255917870-255917962 c
            208-313             JAXUCZ010000001.1  255915255-255915360 c
FEATURES             Location/Qualifiers
     source          1..313
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q54"
     gene            1..313
                     /gene="Atp5mk"
                     /gene_synonym="Atp5md; Dapit; Usmg5"
                     /note="ATP synthase membrane subunit K"
                     /db_xref="GeneID:171069"
                     /db_xref="RGD:631426"
     exon            1..18
                     /gene="Atp5mk"
                     /gene_synonym="Atp5md; Dapit; Usmg5"
                     /inference="alignment:Splign:2.1.0"
     exon            19..114
                     /gene="Atp5mk"
                     /gene_synonym="Atp5md; Dapit; Usmg5"
                     /inference="alignment:Splign:2.1.0"
     CDS             28..204
                     /gene="Atp5mk"
                     /gene_synonym="Atp5md; Dapit; Usmg5"
                     /note="up-regulated during skeletal muscle growth protein
                     5; upregulated during skeletal muscle growth 5;
                     diabetes-associated protein in insulin-sensitive tissues;
                     up-regulated during skeletal muscle growth 5 homolog; ATP
                     synthase membrane subunit DAPIT, mitochondrial"
                     /codon_start=1
                     /product="ATP synthase membrane subunit K, mitochondrial"
                     /protein_id="NP_598228.1"
                     /db_xref="GeneID:171069"
                     /db_xref="RGD:631426"
                     /translation="MAGPESDGQFQFTGIKKYFNSYTLTGRMNCVLATYGGIALLVLY
                     FKLRPKKTPAVKAT"
     exon            115..207
                     /gene="Atp5mk"
                     /gene_synonym="Atp5md; Dapit; Usmg5"
                     /inference="alignment:Splign:2.1.0"
     exon            208..313
                     /gene="Atp5mk"
                     /gene_synonym="Atp5md; Dapit; Usmg5"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gtgattcgga cgaagaagat tgaagtcatg gctggtccag aaagtgatgg ccaattccag
       61 ttcactggta ttaaaaaata tttcaactct tataccctca caggtagaat gaattgtgtc
      121 ctggccacat atggaggcat tgctttgttg gtcctatact ttaagttaag gcctaaaaaa
      181 accccagctg tgaaagcaac ataaatggat tttgaaatgt ctggccttat ctgttaagtc
      241 ccacgcctga agaagctgat gtgaactcat catgtaatac tcaatttgta caataaatta
      301 tgaacctgga aaa
//
