LOCUS       NM_133556                749 bp    mRNA    linear   ROD 20-SEP-2024
DEFINITION  Rattus norvegicus ATP synthase membrane subunit c locus 2
            (Atp5mc2), mRNA; nuclear gene for mitochondrial product.
ACCESSION   NM_133556
VERSION     NM_133556.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 749)
  AUTHORS   Morgenstern,M., Peikert,C.D., Lubbert,P., Suppanz,I., Klemm,C.,
            Alka,O., Steiert,C., Naumenko,N., Schendzielorz,A., Melchionda,L.,
            Muhlhauser,W.W.D., Knapp,B., Busch,J.D., Stiller,S.B.,
            Dannenmaier,S., Lindau,C., Licheva,M., Eickhorst,C., Galbusera,R.,
            Zerbes,R.M., Ryan,M.T., Kraft,C., Kozjak-Pavlovic,V., Drepper,F.,
            Dennerlein,S., Oeljeklaus,S., Pfanner,N., Wiedemann,N. and
            Warscheid,B.
  TITLE     Quantitative high-confidence human mitochondrial proteome and its
            dynamics in cellular context
  JOURNAL   Cell Metab 33 (12), 2464-2483 (2021)
   PUBMED   34800366
REFERENCE   2  (bases 1 to 749)
  AUTHORS   Bruggemann,M., Gromes,A., Poss,M., Schmidt,D., Klumper,N.,
            Tolkach,Y., Dietrich,D., Kristiansen,G., Muller,S.C. and
            Ellinger,J.
  TITLE     Systematic Analysis of the Expression of the Mitochondrial ATP
            Synthase (Complex V) Subunits in Clear Cell Renal Cell Carcinoma
  JOURNAL   Transl Oncol 10 (4), 661-668 (2017)
   PUBMED   28672194
REFERENCE   3  (bases 1 to 749)
  AUTHORS   Campo,G., Morciano,G., Pavasini,R., Bonora,M., Sbano,L.,
            Biscaglia,S., Bovolenta,M., Pinotti,M., Punzetti,S., Rizzo,P.,
            Aquila,G., Giorgi,C., Ferrari,R. and Pinton,P.
  TITLE     Fo ATP synthase C subunit serum levels in patients with ST-segment
            Elevation Myocardial Infarction: Preliminary findings
  JOURNAL   Int J Cardiol 221, 993-997 (2016)
   PUBMED   27441480
REFERENCE   4  (bases 1 to 749)
  AUTHORS   Kitchen,M.O., Bryan,R.T., Emes,R.D., Glossop,J.R., Luscombe,C.,
            Cheng,K.K., Zeegers,M.P., James,N.D., Devall,A.J., Mein,C.A.,
            Gommersall,L., Fryer,A.A. and Farrell,W.E.
  TITLE     Quantitative genome-wide methylation analysis of high-grade
            non-muscle invasive bladder cancer
  JOURNAL   Epigenetics 11 (3), 237-246 (2016)
   PUBMED   26929985
REFERENCE   5  (bases 1 to 749)
  AUTHORS   Xie,X., Man,X., Zhu,Z., Yuan,D. and Huang,S.
  TITLE     Tumor suppressor RIZ1 in obesity and the PI3K/AKT/mTOR pathway
  JOURNAL   Obesity (Silver Spring) 24 (2), 389-397 (2016)
   PUBMED   26709097
REFERENCE   6  (bases 1 to 749)
  AUTHORS   Morris,M.R., Ricketts,C.J., Gentle,D., McRonald,F., Carli,N.,
            Khalili,H., Brown,M., Kishida,T., Yao,M., Banks,R.E., Clarke,N.,
            Latif,F. and Maher,E.R.
  TITLE     Genome-wide methylation analysis identifies epigenetically
            inactivated candidate tumour suppressor genes in renal cell
            carcinoma
  JOURNAL   Oncogene 30 (12), 1390-1401 (2011)
   PUBMED   21132003
REFERENCE   7  (bases 1 to 749)
  AUTHORS   Li,H.S., Zhang,J.Y., Thompson,B.S., Deng,X.Y., Ford,M.E.,
            Wood,P.G., Stolz,D.B., Eagon,P.K. and Whitcomb,D.C.
  TITLE     Rat mitochondrial ATP synthase ATP5G3: cloning and upregulation in
            pancreas after chronic ethanol feeding
  JOURNAL   Physiol Genomics 6 (2), 91-98 (2001)
   PUBMED   11459924
  REMARK    Publication Status: Online-Only
REFERENCE   8  (bases 1 to 749)
  AUTHORS   McGeoch,J.E. and Guidotti,G.
  TITLE     Batten disease and the control of the Fo subunit c pore by cGMP and
            calcium
  JOURNAL   Eur J Paediatr Neurol 5 Suppl A, 147-150 (2001)
   PUBMED   11588987
REFERENCE   9  (bases 1 to 749)
  AUTHORS   Andersson,U., Houstek,J. and Cannon,B.
  TITLE     ATP synthase subunit c expression: physiological regulation of the
            P1 and P2 genes
  JOURNAL   Biochem J 323 (Pt 2) (Pt 2), 379-385 (1997)
   PUBMED   9163327
REFERENCE   10 (bases 1 to 749)
  AUTHORS   Higuti,T., Kuroiwa,K., Kawamura,Y., Morimoto,K. and Tsujita,H.
  TITLE     Molecular cloning and sequence of cDNAs for the import precursors
            of oligomycin sensitivity conferring protein, ATPase inhibitor
            protein, and subunit c of H(+)-ATP synthase in rat mitochondria
  JOURNAL   Biochim Biophys Acta 1172 (3), 311-314 (1993)
   PUBMED   8448208
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC128726.1.
            
            On Feb 25, 2007 this sequence version replaced NM_133556.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC128726.1, FQ209535.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132301, SAMN06621351
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            gene product(s) localized to mito. :: inferred from homology
            RefSeq Select criteria             :: based on conservation,
                                                  expression, longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..749
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="7"
                     /map="7q36"
     gene            1..749
                     /gene="Atp5mc2"
                     /gene_synonym="Atp5g2"
                     /note="ATP synthase membrane subunit c locus 2"
                     /db_xref="GeneID:171082"
                     /db_xref="RGD:620051"
     exon            1..17
                     /gene="Atp5mc2"
                     /gene_synonym="Atp5g2"
                     /inference="alignment:Splign:2.1.0"
     exon            18..87
                     /gene="Atp5mc2"
                     /gene_synonym="Atp5g2"
                     /inference="alignment:Splign:2.1.0"
     CDS             49..474
                     /gene="Atp5mc2"
                     /gene_synonym="Atp5g2"
                     /note="ATP synthase lipid-binding protein, mitochondrial;
                     ATPase protein 9; ATPase subunit c; ATP synthase
                     proteolipid P2; ATP synthase, H+ transporting,
                     mitochondrial Fo complex, subunit C2 (subunit 9); ATP
                     synthase, H+ transporting, mitochondrial F0 complex,
                     subunit c (subunit 9); ATP synthase, H+ transporting,
                     mitochondrial F0 complex, subunit C2 (subunit 9); ATP
                     synthase F(0) complex subunit C2, mitochondrial"
                     /codon_start=1
                     /product="ATP synthase F(0) complex subunit C2,
                     mitochondrial precursor"
                     /protein_id="NP_598240.1"
                     /db_xref="GeneID:171082"
                     /db_xref="RGD:620051"
                     /translation="MYACSKFVSTRSLIRSTSQLLSRPLSAVELKRPQMPTDEGLSCL
                     AVRRPLTSLIPSRSFQTSAISRDIDTAAKFIGAGAATVGVAGSGAGIGTVFGSLIIGY
                     ARNPSLKQQLFSYAILGFALSEAMGLFCLMVAFLILFAM"
     exon            88..165
                     /gene="Atp5mc2"
                     /gene_synonym="Atp5g2"
                     /inference="alignment:Splign:2.1.0"
     exon            166..359
                     /gene="Atp5mc2"
                     /gene_synonym="Atp5g2"
                     /inference="alignment:Splign:2.1.0"
     exon            360..624
                     /gene="Atp5mc2"
                     /gene_synonym="Atp5g2"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ctctaccctg ggagcagctc ttctgccttt gcccctcacc cctgaaaaat gtatgcctgc
       61 tccaagttcg tctctacccg ctccctgatc aggagcacct ctcagctgct gagccgtccg
      121 ctctctgcag tggagttaaa gcgaccacag atgcccacag atgagggcct cagctgcttg
      181 gcagtccggc ggcctctgac ctcgcttatc cctagccgca gcttccaaac cagcgccatt
      241 tcaagggaca ttgacacagc tgccaagttc attggagctg gggctgctac agttggggtg
      301 gccggttctg gagcaggaat tgggactgtt tttgggagtc tcatcattgg ctatgccagg
      361 aacccctctc tgaagcagca actcttctcc tatgcgattc tgggcttcgc cctctctgag
      421 gccatggggc tcttttgcct aatggtggcc ttcctcatcc tcttcgccat gtgaagcagc
      481 tgtctccacg tccacctccc atggttcttc cgtgtctcgt ctgccctgtg tgttcctttt
      541 cctgtgcctc cccaagaagt ctggggaaag tgcttggctc agggtttgac agagagaaga
      601 caaataaata ctgtattaat aagaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
      661 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
      721 aaaaaaaaaa aaaaaaaaaa aaaaaaaaa
//
