LOCUS       NM_139099                372 bp    mRNA    linear   ROD 22-SEP-2024
DEFINITION  Rattus norvegicus ATP synthase F1 subunit epsilon (Atp5f1e), mRNA;
            nuclear gene for mitochondrial product.
ACCESSION   NM_139099
VERSION     NM_139099.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 372)
  AUTHORS   Morgenstern,M., Peikert,C.D., Lubbert,P., Suppanz,I., Klemm,C.,
            Alka,O., Steiert,C., Naumenko,N., Schendzielorz,A., Melchionda,L.,
            Muhlhauser,W.W.D., Knapp,B., Busch,J.D., Stiller,S.B.,
            Dannenmaier,S., Lindau,C., Licheva,M., Eickhorst,C., Galbusera,R.,
            Zerbes,R.M., Ryan,M.T., Kraft,C., Kozjak-Pavlovic,V., Drepper,F.,
            Dennerlein,S., Oeljeklaus,S., Pfanner,N., Wiedemann,N. and
            Warscheid,B.
  TITLE     Quantitative high-confidence human mitochondrial proteome and its
            dynamics in cellular context
  JOURNAL   Cell Metab 33 (12), 2464-2483 (2021)
   PUBMED   34800366
REFERENCE   2  (bases 1 to 372)
  AUTHORS   Xia,W., Wan,Y., Li,Y.Y., Zeng,H., Lv,Z., Li,G., Wei,Z. and Xu,S.Q.
  TITLE     PFOS prenatal exposure induce mitochondrial injury and gene
            expression change in hearts of weaned SD rats
  JOURNAL   Toxicology 282 (1-2), 23-29 (2011)
   PUBMED   21251948
REFERENCE   3  (bases 1 to 372)
  AUTHORS   Mayr,J.A., Havlickova,V., Zimmermann,F., Magler,I., Kaplanova,V.,
            Jesina,P., Pecinova,A., Nuskova,H., Koch,J., Sperl,W. and
            Houstek,J.
  TITLE     Mitochondrial ATP synthase deficiency due to a mutation in the
            ATP5E gene for the F1 epsilon subunit
  JOURNAL   Hum Mol Genet 19 (17), 3430-3439 (2010)
   PUBMED   20566710
REFERENCE   4  (bases 1 to 372)
  AUTHORS   Meyer,B., Wittig,I., Trifilieff,E., Karas,M. and Schagger,H.
  TITLE     Identification of two proteins associated with mammalian ATP
            synthase
  JOURNAL   Mol Cell Proteomics 6 (10), 1690-1699 (2007)
   PUBMED   17575325
REFERENCE   5  (bases 1 to 372)
  AUTHORS   Mootha,V.K., Bunkenborg,J., Olsen,J.V., Hjerrild,M.,
            Wisniewski,J.R., Stahl,E., Bolouri,M.S., Ray,H.N., Sihag,S.,
            Kamal,M., Patterson,N., Lander,E.S. and Mann,M.
  TITLE     Integrated analysis of protein composition, tissue diversity, and
            gene regulation in mouse mitochondria
  JOURNAL   Cell 115 (5), 629-640 (2003)
   PUBMED   14651853
REFERENCE   6  (bases 1 to 372)
  AUTHORS   Aggeler,R., Coons,J., Taylor,S.W., Ghosh,S.S., Garcia,J.J.,
            Capaldi,R.A. and Marusich,M.F.
  TITLE     A functionally active human F1F0 ATPase can be purified by
            immunocapture from heart tissue and fibroblast cell lines. Subunit
            structure and activity studies
  JOURNAL   J Biol Chem 277 (37), 33906-33912 (2002)
   PUBMED   12110673
REFERENCE   7  (bases 1 to 372)
  AUTHORS   Ko,Y.H., Hullihen,J., Hong,S. and Pedersen,P.L.
  TITLE     Mitochondrial F(0)F(1) ATP synthase. Subunit regions on the F1
            motor shielded by F(0), Functional significance, and evidence for
            an involvement of the unique F(0) subunit F(6)
  JOURNAL   J Biol Chem 275 (42), 32931-32939 (2000)
   PUBMED   10887193
REFERENCE   8  (bases 1 to 372)
  AUTHORS   Tu,Q., Yu,L., Zhang,P., Zhang,M., Zhang,H., Jiang,J., Chen,C. and
            Zhao,S.
  TITLE     Cloning, characterization and mapping of the human ATP5E gene,
            identification of pseudogene ATP5EP1, and definition of the ATP5E
            motif
  JOURNAL   Biochem J 347 Pt 1 (Pt 1), 17-21 (2000)
   PUBMED   10727396
REFERENCE   9  (bases 1 to 372)
  AUTHORS   Higuti,T., Yoshihara,Y., Kuroiwa,K., Kawamura,Y., Toda,H. and
            Sakiyama,F.
  TITLE     A simple, rapid method for purification of epsilon-subunit,
            coupling factor 6, subunit d, and subunit e from rat liver H(+)-ATP
            synthase and determination of the complete amino acid sequence of
            epsilon-subunit
  JOURNAL   J Biol Chem 267 (31), 22658-22661 (1992)
   PUBMED   1429613
REFERENCE   10 (bases 1 to 372)
  AUTHORS   Pedersen,P.L., Williams,N. and Hullihen,J.
  TITLE     Mitochondrial ATP synthase: dramatic Mg2+-induced alterations in
            the structure and function of the F1-ATPase moiety
  JOURNAL   Biochemistry 26 (26), 8631-8637 (1987)
   PUBMED   2894844
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from
            JAXUCZ010000003.1.
            
            On Nov 27, 2020 this sequence version replaced NM_139099.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AF010323.1, FQ214935.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760386
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            gene product(s) localized to mito. :: inferred from homology
            RefSeq Select criteria             :: based on single
                                                  protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-93                JAXUCZ010000003.1  183680080-183680172 c
            94-220              JAXUCZ010000003.1  183678671-183678797 c
            221-372             JAXUCZ010000003.1  183677270-183677421 c
FEATURES             Location/Qualifiers
     source          1..372
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="3"
                     /map="3q43"
     gene            1..372
                     /gene="Atp5f1e"
                     /gene_synonym="Atp5e"
                     /note="ATP synthase F1 subunit epsilon"
                     /db_xref="GeneID:245958"
                     /db_xref="RGD:621374"
     exon            1..93
                     /gene="Atp5f1e"
                     /gene_synonym="Atp5e"
                     /inference="alignment:Splign:2.1.0"
     CDS             62..217
                     /gene="Atp5f1e"
                     /gene_synonym="Atp5e"
                     /EC_number="7.1.2.2"
                     /note="ATPase subunit epsilon; ATP synthase, H+
                     transporting, mitochondrial F1 complex, epsilon subunit"
                     /codon_start=1
                     /product="ATP synthase subunit epsilon, mitochondrial"
                     /protein_id="NP_620799.1"
                     /db_xref="GeneID:245958"
                     /db_xref="RGD:621374"
                     /translation="MVAYWRQAGLSYIRFSQICAKAVRDALKTEFKANAEKTSGTSIK
                     TVKIKKE"
     exon            94..220
                     /gene="Atp5f1e"
                     /gene_synonym="Atp5e"
                     /inference="alignment:Splign:2.1.0"
     exon            221..372
                     /gene="Atp5f1e"
                     /gene_synonym="Atp5e"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gggctcaggc tactctgaag cgacccagcg gttctgcctg acacgccccg ctcgagacac
       61 catggtggcg tactggcgac aggctggact cagctacatc cggttctccc agatctgtgc
      121 aaaagcagtg agggatgccc tgaagactga gttcaaagcg aacgctgaga agacttcggg
      181 caccagcata aaaacagtga aaataaagaa ggagtagccg agcctgactg aagcctgacg
      241 tgcggagtct tccaggtgaa gcatgtgggc acctgttccg gcagatggag gtcagccgta
      301 cctcctggag acagacaccc atcttgttga tgaattgact atgccaataa attaacacgg
      361 ttcactctcg gc
//
