LOCUS       NM_139106                799 bp    mRNA    linear   ROD 22-SEP-2024
DEFINITION  Rattus norvegicus ATP synthase F1 subunit delta (Atp5f1d), mRNA;
            nuclear gene for mitochondrial product.
ACCESSION   NM_139106
VERSION     NM_139106.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 799)
  AUTHORS   Morgenstern,M., Peikert,C.D., Lubbert,P., Suppanz,I., Klemm,C.,
            Alka,O., Steiert,C., Naumenko,N., Schendzielorz,A., Melchionda,L.,
            Muhlhauser,W.W.D., Knapp,B., Busch,J.D., Stiller,S.B.,
            Dannenmaier,S., Lindau,C., Licheva,M., Eickhorst,C., Galbusera,R.,
            Zerbes,R.M., Ryan,M.T., Kraft,C., Kozjak-Pavlovic,V., Drepper,F.,
            Dennerlein,S., Oeljeklaus,S., Pfanner,N., Wiedemann,N. and
            Warscheid,B.
  TITLE     Quantitative high-confidence human mitochondrial proteome and its
            dynamics in cellular context
  JOURNAL   Cell Metab 33 (12), 2464-2483 (2021)
   PUBMED   34800366
REFERENCE   2  (bases 1 to 799)
  AUTHORS   Olahova,M., Yoon,W.H., Thompson,K., Jangam,S., Fernandez,L.,
            Davidson,J.M., Kyle,J.E., Grove,M.E., Fisk,D.G., Kohler,J.N.,
            Holmes,M., Dries,A.M., Huang,Y., Zhao,C., Contrepois,K.,
            Zappala,Z., Fresard,L., Waggott,D., Zink,E.M., Kim,Y.M.,
            Heyman,H.M., Stratton,K.G., Webb-Robertson,B.M., Snyder,M.,
            Merker,J.D., Montgomery,S.B., Fisher,P.G., Feichtinger,R.G.,
            Mayr,J.A., Hall,J., Barbosa,I.A., Simpson,M.A., Deshpande,C.,
            Waters,K.M., Koeller,D.M., Metz,T.O., Morris,A.A., Schelley,S.,
            Cowan,T., Friederich,M.W., McFarland,R., Van Hove,J.L.K.,
            Enns,G.M., Yamamoto,S., Ashley,E.A., Wangler,M.F., Taylor,R.W.,
            Bellen,H.J., Bernstein,J.A. and Wheeler,M.T.
  CONSRTM   Undiagnosed Diseases Network
  TITLE     Biallelic Mutations in ATP5F1D, which Encodes a Subunit of ATP
            Synthase, Cause a Metabolic Disorder
  JOURNAL   Am J Hum Genet 102 (3), 494-504 (2018)
   PUBMED   29478781
REFERENCE   3  (bases 1 to 799)
  AUTHORS   Wang,Y., Zhao,Y., Jiang,W., Zhao,X., Fan,G., Zhang,H., Shen,P.,
            He,J. and Fan,X.
  TITLE     iTRAQ-Based Proteomic Analysis Reveals Recovery of Impaired
            Mitochondrial Function in Ischemic Myocardium by Shenmai Formula
  JOURNAL   J Proteome Res 17 (2), 794-803 (2018)
   PUBMED   29300489
REFERENCE   4  (bases 1 to 799)
  AUTHORS   Arias,N., Pico,C., Teresa Macarulla,M., Oliver,P., Miranda,J.,
            Palou,A. and Portillo,M.P.
  TITLE     A combination of resveratrol and quercetin induces browning in
            white adipose tissue of rats fed an obesogenic diet
  JOURNAL   Obesity (Silver Spring) 25 (1), 111-121 (2017)
   PUBMED   27874268
REFERENCE   5  (bases 1 to 799)
  AUTHORS   Armand-Ugon,M., Ansoleaga,B., Berjaoui,S. and Ferrer,I.
  TITLE     Reduced Mitochondrial Activity is Early and Steady in the
            Entorhinal Cortex but it is Mainly Unmodified in the Frontal Cortex
            in Alzheimer's Disease
  JOURNAL   Curr Alzheimer Res 14 (12), 1327-1334 (2017)
   PUBMED   28474567
REFERENCE   6  (bases 1 to 799)
  AUTHORS   Schertzer,J.D., Green,H.J., Duhamel,T.A. and Tupling,A.R.
  TITLE     Mechanisms underlying increases in SR Ca2+-ATPase activity after
            exercise in rat skeletal muscle
  JOURNAL   Am J Physiol Endocrinol Metab 284 (3), E597-E610 (2003)
   PUBMED   12409282
REFERENCE   7  (bases 1 to 799)
  AUTHORS   Aggeler,R., Coons,J., Taylor,S.W., Ghosh,S.S., Garcia,J.J.,
            Capaldi,R.A. and Marusich,M.F.
  TITLE     A functionally active human F1F0 ATPase can be purified by
            immunocapture from heart tissue and fibroblast cell lines. Subunit
            structure and activity studies
  JOURNAL   J Biol Chem 277 (37), 33906-33912 (2002)
   PUBMED   12110673
REFERENCE   8  (bases 1 to 799)
  AUTHORS   Ko,Y.H., Hullihen,J., Hong,S. and Pedersen,P.L.
  TITLE     Mitochondrial F(0)F(1) ATP synthase. Subunit regions on the F1
            motor shielded by F(0), Functional significance, and evidence for
            an involvement of the unique F(0) subunit F(6)
  JOURNAL   J Biol Chem 275 (42), 32931-32939 (2000)
   PUBMED   10887193
REFERENCE   9  (bases 1 to 799)
  AUTHORS   Pan,W., Ko,Y.H. and Pedersen,P.L.
  TITLE     Delta subunit of rat liver mitochondrial ATP synthase: molecular
            description and novel insights into the nature of its association
            with the F1-moiety
  JOURNAL   Biochemistry 37 (19), 6911-6923 (1998)
   PUBMED   9578578
REFERENCE   10 (bases 1 to 799)
  AUTHORS   Pedersen,P.L., Williams,N. and Hullihen,J.
  TITLE     Mitochondrial ATP synthase: dramatic Mg2+-induced alterations in
            the structure and function of the F1-ATPase moiety
  JOURNAL   Biochemistry 26 (26), 8631-8637 (1987)
   PUBMED   2894844
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from
            JAXUCZ010000007.1.
            
            On Nov 27, 2020 this sequence version replaced NM_139106.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: U00926.1, CB583458.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN12840108, SAMN12840115
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            gene product(s) localized to mito. :: inferred from homology
            RefSeq Select criteria             :: based on conservation,
                                                  expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-183               JAXUCZ010000007.1  10214168-10214350   c
            184-337             JAXUCZ010000007.1  10213002-10213155   c
            338-426             JAXUCZ010000007.1  10211778-10211866   c
            427-799             JAXUCZ010000007.1  10211264-10211636   c
FEATURES             Location/Qualifiers
     source          1..799
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="7"
                     /map="7q11"
     gene            1..799
                     /gene="Atp5f1d"
                     /gene_synonym="Atp5d"
                     /note="ATP synthase F1 subunit delta"
                     /db_xref="GeneID:245965"
                     /db_xref="RGD:621372"
     exon            1..183
                     /gene="Atp5f1d"
                     /gene_synonym="Atp5d"
                     /inference="alignment:Splign:2.1.0"
     CDS             43..549
                     /gene="Atp5f1d"
                     /gene_synonym="Atp5d"
                     /EC_number="3.6.1.14"
                     /note="ATP synthase subunit delta, mitochondrial; F-ATPase
                     delta subunit; ATP synthase, H+ transporting,
                     mitochondrial F1 complex, delta subunit"
                     /codon_start=1
                     /product="ATP synthase subunit delta, mitochondrial
                     precursor"
                     /protein_id="NP_620806.2"
                     /db_xref="GeneID:245965"
                     /db_xref="RGD:621372"
                     /translation="MLPAALLRHPGLRRLVLQARTYAQAAASPAPAAGPGQMSFTFAS
                     PTQVFFDGANVRQVDVPTLTGAFGILASHVPTLQVLRPGLVVVHAEDGTTTKYFVSSG
                     SVTVNADSSVQLLAEEVVTLDMLDLGAARANLEKAQSELSGAADEAARAEIQIRIEAN
                     EALVKALE"
     exon            184..337
                     /gene="Atp5f1d"
                     /gene_synonym="Atp5d"
                     /inference="alignment:Splign:2.1.0"
     exon            338..426
                     /gene="Atp5f1d"
                     /gene_synonym="Atp5d"
                     /inference="alignment:Splign:2.1.0"
     exon            427..799
                     /gene="Atp5f1d"
                     /gene_synonym="Atp5d"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ctgctgtccg ctaagctaaa gtccactgac gtttccgcca ccatgctgcc cgccgcattg
       61 cttcgtcacc caggtctgcg ccgtctggtg ctccaggcgc gtacgtacgc ccaggccgcc
      121 gcctcacctg cccccgccgc tgggcctgga cagatgtcct tcaccttcgc ctccccgacg
      181 caggtgttct ttgatggtgc caatgtccgg caagtggatg tgcctacgct gactggagcc
      241 tttggcatcc tggcatccca tgtccccaca ctacaggtcc tacggcctgg gctggtagtg
      301 gttcatgcgg aagatggcac cacaactaag tattttgtga gcagcggctc cgtcactgtg
      361 aatgcggact cctctgtgca attactagct gaagaagtcg tgacactgga catgctggac
      421 ctcggggcag cccgggcaaa cctggagaag gcgcagtcag agctgtcagg ggcagcagat
      481 gaggcagcac gggctgagat ccaaatccgg atcgaggcca atgaagccct ggtgaaggcc
      541 ctggagtagg cgtactttgt ctgtcaccca cagggtaaca gaggcaggtc ctggggggct
      601 gaagtcgcca ccagggggca gcagtgctcc ggttactggc ttaaagcttc cctggtgctg
      661 cctgccaggt catggagggc ttccccaggc ttccagagtc tgggatcccc aggatgcctc
      721 tggagagctg gccttgattg cccctcaaag ccacccggac agtcagctgg cccagcctat
      781 ctgcattaaa taccaggaa
//
