LOCUS       NM_134364               1759 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus ATP synthase F1 subunit beta (Atp5f1b), mRNA;
            nuclear gene for mitochondrial product.
ACCESSION   NM_134364 XM_343136
VERSION     NM_134364.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1759)
  AUTHORS   Shichiri,M., Nonaka,D., Lee,L.J. and Tanaka,K.
  TITLE     Identification of the salusin-beta receptor using proteoliposomes
            embedded with endogenous membrane proteins
  JOURNAL   Sci Rep 8 (1), 17865 (2018)
   PUBMED   30552345
  REMARK    GeneRIF: Here, the authors show that the beta-chain of ATP synthase
            is a cell surface receptor for salusin-beta
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1759)
  AUTHORS   Aiello,F.B., Guszczynski,T., Li,W., Hixon,J.A., Jiang,Q.,
            Hodge,D.L., Massignan,T., Di Lisio,C., Merchant,A., Procopio,A.D.,
            Bonetto,V. and Durum,S.K.
  TITLE     IL-7-induced phosphorylation of the adaptor Crk-like and other
            targets
  JOURNAL   Cell Signal 47, 131-141 (2018)
   PUBMED   29581031
REFERENCE   3  (bases 1 to 1759)
  AUTHORS   Li,W., Li,S.J., Yin,T.L., Yang,J. and Cheng,Y.
  TITLE     ATP synthase beta-subunit abnormality in pancreas islets of rats
            with polycystic ovary syndrome and type 2 diabetes mellitus
  JOURNAL   J Huazhong Univ Sci Technolog Med Sci 37 (2), 210-216 (2017)
   PUBMED   28397049
REFERENCE   4  (bases 1 to 1759)
  AUTHORS   Qiu,P., Man,S., Li,J., Liu,J., Zhang,L., Yu,P. and Gao,W.
  TITLE     Overdose Intake of Curcumin Initiates the Unbalanced State of
            Bodies
  JOURNAL   J Agric Food Chem 64 (13), 2765-2771 (2016)
   PUBMED   26978516
REFERENCE   5  (bases 1 to 1759)
  AUTHORS   Mukherjee,R. and Yun,J.W.
  TITLE     Pharmacological inhibition of galectin-1 by lactulose alleviates
            weight gain in diet-induced obese rats
  JOURNAL   Life Sci 148, 112-117 (2016)
   PUBMED   26880535
REFERENCE   6  (bases 1 to 1759)
  AUTHORS   Bianchet,M., Ysern,X., Hullihen,J., Pedersen,P.L. and Amzel,L.M.
  TITLE     Mitochondrial ATP synthase. Quaternary structure of the F1 moiety
            at 3.6 A determined by x-ray diffraction analysis
  JOURNAL   J Biol Chem 266 (31), 21197-21201 (1991)
   PUBMED   1834656
REFERENCE   7  (bases 1 to 1759)
  AUTHORS   Garboczi,D.N., Thomas,P.J. and Pedersen,P.L.
  TITLE     Rat liver mitochondrial ATP synthase. Effects of mutations in the
            glycine-rich region of a beta subunit peptide on its interaction
            with adenine nucleotides
  JOURNAL   J Biol Chem 265 (24), 14632-14637 (1990)
   PUBMED   2143765
REFERENCE   8  (bases 1 to 1759)
  AUTHORS   Cretin,F., Baggetto,L.G., Denoroy,L. and Godinot,C.
  TITLE     N-terminal sequence of the rat liver beta-subunit in the
            mitochondrial ATPase-ATPsynthase
  JOURNAL   Biochem Biophys Res Commun 164 (3), 1165-1169 (1989)
   PUBMED   2531579
REFERENCE   9  (bases 1 to 1759)
  AUTHORS   Boulet,D., Poirier,J. and Cote,C.
  TITLE     Studies on the biogenesis of the mammalian ATP synthase complex:
            isolation and characterization of a full-length cDNA encoding the
            rat F1-beta-subunit
  JOURNAL   Biochem Biophys Res Commun 159 (3), 1184-1190 (1989)
   PUBMED   2522775
REFERENCE   10 (bases 1 to 1759)
  AUTHORS   Ohta,S. and Kagawa,Y.
  TITLE     Human F1-ATPase: molecular cloning of cDNA for the beta subunit
  JOURNAL   J Biochem 99 (1), 135-141 (1986)
   PUBMED   2870059
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            M25301.1, M19044.1 and M57634.1.
            
            On Nov 15, 2004 this sequence version replaced XM_343136.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC099743.1, SRR8487226.111057.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132261, SAMD00132262
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            gene product(s) localized to mito. :: inferred from homology
            RefSeq Select criteria             :: based on single
                                                  protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-202               M25301.1           6-207
            203-1221            M19044.1           19-1037
            1222-1308           M57634.1           687-773
            1309-1759           M19044.1           1125-1575
FEATURES             Location/Qualifiers
     source          1..1759
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="7"
                     /map="7q11"
     gene            1..1759
                     /gene="Atp5f1b"
                     /gene_synonym="Atp5b"
                     /note="ATP synthase F1 subunit beta"
                     /db_xref="GeneID:171374"
                     /db_xref="RGD:621368"
     exon            1..149
                     /gene="Atp5f1b"
                     /gene_synonym="Atp5b"
                     /inference="alignment:Splign:2.1.0"
     CDS             23..1612
                     /gene="Atp5f1b"
                     /gene_synonym="Atp5b"
                     /EC_number="7.1.2.2"
                     /note="ATP synthase subunit beta, mitochondrial;
                     mitochondrial ATP synthase beta subunit; ATP synthase, H+
                     transporting mitochondrial F1 complex, beta subunit; ATP
                     synthase, H+ transporting, mitochondrial F1 complex, beta
                     polypeptide"
                     /codon_start=1
                     /product="ATP synthase subunit beta, mitochondrial
                     precursor"
                     /protein_id="NP_599191.1"
                     /db_xref="GeneID:171374"
                     /db_xref="RGD:621368"
                     /translation="MLSLVGRVASASASGALRGLNPLAALPQAHLLLRTAPAGVHPAR
                     DYAAQSSAAPKAGTATGQIVAVIGAVVDVQFDEGLPPILNALEVQGRESRLVLEVAQH
                     LGESTVRTIAMDGTEGLVRGQKVLDSGAPIKIPVGPETLGRIMNVIGEPIDERGPIKT
                     KQFAPIHAEAPEFIEMSVEQEILVTGIKVVDLLAPYAKGGKIGLFGGAGVGKTVLIME
                     LINNVAKAHGGYSVFAGVGERTREGNDLYHEMIESGVINLKDATSKVALVYGQMNEPP
                     GARARVALTGLTVAEYFRDQEGQDVLLFIDNIFRFTQAGSEVSALLGRIPSAVGYQPT
                     LATDMGTMQERITTTKKGSITSVQAIYVPADDLTDPAPATTFAHLDATTVLSRAIAEL
                     GIYPAVDPLDSTSRIMDPNIVGSEHYDVARGVQKILQDYKSLQDIIAILGMDELSEED
                     KLTVSRARKIQRFLSQPFQVAEVFTGHMGKLVPLKETIKGFQQILAGDYDHLPEQAFY
                     MVGPIEEAVAKADKLAEEHGS"
     exon            150..332
                     /gene="Atp5f1b"
                     /gene_synonym="Atp5b"
                     /inference="alignment:Splign:2.1.0"
     exon            333..507
                     /gene="Atp5f1b"
                     /gene_synonym="Atp5b"
                     /inference="alignment:Splign:2.1.0"
     exon            508..629
                     /gene="Atp5f1b"
                     /gene_synonym="Atp5b"
                     /inference="alignment:Splign:2.1.0"
     exon            630..814
                     /gene="Atp5f1b"
                     /gene_synonym="Atp5b"
                     /inference="alignment:Splign:2.1.0"
     exon            815..973
                     /gene="Atp5f1b"
                     /gene_synonym="Atp5b"
                     /inference="alignment:Splign:2.1.0"
     exon            974..1096
                     /gene="Atp5f1b"
                     /gene_synonym="Atp5b"
                     /inference="alignment:Splign:2.1.0"
     exon            1097..1309
                     /gene="Atp5f1b"
                     /gene_synonym="Atp5b"
                     /inference="alignment:Splign:2.1.0"
     exon            1310..1511
                     /gene="Atp5f1b"
                     /gene_synonym="Atp5b"
                     /inference="alignment:Splign:2.1.0"
     exon            1512..1759
                     /gene="Atp5f1b"
                     /gene_synonym="Atp5b"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cagtctccac ccggactccg ccatgttgag tcttgtgggg cgtgtggcct cggcctcggc
       61 ctccggggcc ttacggggac tcaacccttt ggcggcgctg ccacaggcgc atcttctact
      121 acgaaccgct cccgccgggg tccatcctgc cagagactat gcggcgcagt cgtctgcggc
      181 cccgaaggca ggcaccgcca ccgggcaaat tgtggcagtc atcggcgccg ttgtggatgt
      241 ccagttcgat gagggattac cacctatcct aaatgccttg gaagtgcaag gcagggagag
      301 cagactggtt ttggaggtag cccagcattt aggggagagc accgtcagaa ctattgctat
      361 ggatggcact gaaggcttgg ttagaggcca gaaagtactg gattcggggg caccaatcaa
      421 aattcctgtt ggtcctgaga ccttgggcag aatcatgaat gtcattggag aacctattga
      481 tgagagaggt cctatcaaaa ccaaacaatt cgctcctatt catgctgagg ctcctgaatt
      541 catagagatg agtgttgaac aggaaattct ggtgactggt ataaaggttg tggatctgct
      601 ggccccatac gccaagggtg ggaaaatcgg actcttcgga ggtgctggtg ttggaaagac
      661 agtactgatc atggagctaa tcaacaatgt tgctaaagcc catggtggtt attctgtatt
      721 tgctggtgtt ggtgagagga cccgtgaggg caatgattta taccatgaaa tgattgagtc
      781 tggtgttatc aacctaaaag atgccacttc caaggtagcg ttggtatatg ggcagatgaa
      841 tgaaccgcct ggtgctcgtg cccgggtagc tctgactggt ctgactgttg ctgaatactt
      901 cagagaccag gaaggccaag atgtcctgct gtttattgac aacatcttcc gcttcaccca
      961 ggctggctca gaggtatctg ccttattggg caggatcccg tctgctgtag gctaccagcc
     1021 taccctagcc actgacatgg gtacaatgca ggaaagaatc accaccacca agaagggctc
     1081 gatcacctca gtgcaggcta tctatgtgcc agctgatgac ctgactgacc ctgcccctgc
     1141 aactaccttt gcccatttgg atgctactac tgtgctgtcc cgtgctattg ctgagttggg
     1201 catctatcca gctgtggatc cactggactc cacctctcga attatggatc ccaacatcgt
     1261 tggcagtgag cattatgatg ttgctcgtgg ggtgcaaaag atcctgcagg actacaaatc
     1321 tctccaggac atcattgcca tcttgggtat ggatgaactt tctgaggaag ataaattgac
     1381 tgtgtccagg gcaaggaaga tacagcgctt cttgtcacag ccattccagg ttgctgaggt
     1441 cttcacaggt cacatgggaa agctggtgcc cctgaaggag accattaaag gattccagca
     1501 gatcttagca ggtgactatg accatctccc ggaacaagcc ttctacatgg tgggacccat
     1561 tgaagaagct gtggcaaagg ctgacaagct ggcagaggag catgggtcgt gaggggccct
     1621 tcagccaaac acaacagcac tctgcactga cctccatgct gagagctcag tttgccatgt
     1681 aggccacaca agagccttga ttgaagatgt gatgttctct ctgaagagta tttaaagttt
     1741 tcaataaagt atataccct
//
