LOCUS       NM_134462               3116 bp    mRNA    linear   ROD 05-DEC-2024
DEFINITION  Rattus norvegicus ATPase secretory pathway Ca2+ transporting 2
            (Atp2c2), mRNA.
ACCESSION   NM_134462
VERSION     NM_134462.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 3116)
  AUTHORS   Cross,B.M., Hack,A., Reinhardt,T.A. and Rao,R.
  TITLE     SPCA2 regulates Orai1 trafficking and store independent Ca2+ entry
            in a model of lactation
  JOURNAL   PLoS One 8 (6), e67348 (2013)
   PUBMED   23840669
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3116)
  AUTHORS   Brini,M. and Carafoli,E.
  TITLE     Calcium pumps in health and disease
  JOURNAL   Physiol Rev 89 (4), 1341-1378 (2009)
   PUBMED   19789383
  REMARK    Review article
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AF484685.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AF484685.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN16676784, SAMN16676785
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..3116
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="Sprague-Dawley"
                     /db_xref="taxon:10116"
                     /chromosome="19"
                     /map="19q12"
     gene            1..3116
                     /gene="Atp2c2"
                     /gene_synonym="Spca2"
                     /note="ATPase secretory pathway Ca2+ transporting 2"
                     /db_xref="GeneID:171496"
                     /db_xref="RGD:620647"
     exon            1..193
                     /gene="Atp2c2"
                     /gene_synonym="Spca2"
                     /inference="alignment:Splign:2.1.0"
     CDS             101..2935
                     /gene="Atp2c2"
                     /gene_synonym="Spca2"
                     /EC_number="7.2.2.10"
                     /note="calcium-transporting ATPase 2C2; putative secretory
                     pathway Ca-ATPase SPCA2; secretory pathway Ca(2+)-ATPase
                     2; ATPase, Ca++ transporting, type 2C, member 2;
                     Ca(2+)/Mn(2+)-ATPase 2C2; secretory pathway
                     Ca(2+)-transporting ATPase type 2"
                     /codon_start=1
                     /product="calcium-transporting ATPase type 2C member 2"
                     /protein_id="NP_604457.1"
                     /db_xref="GeneID:171496"
                     /db_xref="RGD:620647"
                     /translation="MGRRFKFLQKLAFLGQNHRYKALERDEVDTLIDEQYELKAIERE
                     KAVAALPPREACKCSKEELARTFHVDLDSGLSEFAVAQRRLVHGWNEFVTDNTEPVWK
                     KYLDQFRNPLILLLLGSSVVSVLTKEYEDAISIALAVLIVVTVGFIQEYRSEKSLEEL
                     TKLVPPECNCLRDGKLRHMLARDLVPGDVVSLSMGDRIPADIRLTEVTDLLVDESSFT
                     GEVEPCSKTDSPLAGGGDLSTLSNVVFMGTLVQCGKGQGVVIGTGEQSQFGEVFKMMR
                     AEETPKTPLQKSMDKLGKQLTVFSFGIIGLLMLVGWVQGKPLLSMFTIGVSLAVAAIP
                     EGLPIVVMVTLVLGVLRMAKKRVIVKKLPIVETLGCCNVICSDKTGTLTANEMTATQL
                     VTSDGFHAEVSGIGYSGEGTVCLLPSKEVIKEFSNVSVGKLVEAGCVANNAVVRKNAV
                     MGQPTEGALVVLAMKMNLGSIKDSYIRKKEIPFSSEQKWMAVRCSLKNEDEEDVYFMK
                     GAFEEVIHHCSTYNNGGIPLPLTPQQKSYCQQEEKKMGSLGLRVLALASGPELGRLTF
                     LGLVGIIDPPRAGVKEAVQALSESDVSVKMVTGDALETALAIGRTIGLCDEKLKAMSG
                     EEVEGMEQDALAARVRQVSVFFRTSPKHKVKIIKALQESGAIVAMTGDGVNDSVALKS
                     ADIGIAMGQTGTDVSKEAADMILVDDDFSAIMSAVEEGKGIFYNIKNFVRFQLSTSIA
                     ALSLITLSTVCNLPNPLNAMQILWVNIIMDGPPAQSLGVEPVDRDALKRPPRSVKDTI
                     LNRALILKILMSAAVILGGTLFIFWREIPENRTSTPRTTTMAFTCFVFFDLFNALSCR
                     SQTKLIFEIGFFRNRMFLYSILGSLLGQLAVIYAPPLQKVFQTENLSALDLLLLTGLA
                     SSVFILSELLKLCEKFCSRAKADQMLPEAV"
     exon            194..304
                     /gene="Atp2c2"
                     /gene_synonym="Spca2"
                     /inference="alignment:Splign:2.1.0"
     exon            305..421
                     /gene="Atp2c2"
                     /gene_synonym="Spca2"
                     /inference="alignment:Splign:2.1.0"
     exon            422..511
                     /gene="Atp2c2"
                     /gene_synonym="Spca2"
                     /inference="alignment:Splign:2.1.0"
     exon            512..547
                     /gene="Atp2c2"
                     /gene_synonym="Spca2"
                     /inference="alignment:Splign:2.1.0"
     exon            548..609
                     /gene="Atp2c2"
                     /gene_synonym="Spca2"
                     /inference="alignment:Splign:2.1.0"
     exon            610..718
                     /gene="Atp2c2"
                     /gene_synonym="Spca2"
                     /inference="alignment:Splign:2.1.0"
     exon            719..868
                     /gene="Atp2c2"
                     /gene_synonym="Spca2"
                     /inference="alignment:Splign:2.1.0"
     exon            869..937
                     /gene="Atp2c2"
                     /gene_synonym="Spca2"
                     /inference="alignment:Splign:2.1.0"
     exon            938..1013
                     /gene="Atp2c2"
                     /gene_synonym="Spca2"
                     /inference="alignment:Splign:2.1.0"
     exon            1014..1080
                     /gene="Atp2c2"
                     /gene_synonym="Spca2"
                     /inference="alignment:Splign:2.1.0"
     exon            1081..1205
                     /gene="Atp2c2"
                     /gene_synonym="Spca2"
                     /inference="alignment:Splign:2.1.0"
     exon            1206..1303
                     /gene="Atp2c2"
                     /gene_synonym="Spca2"
                     /inference="alignment:Splign:2.1.0"
     exon            1304..1405
                     /gene="Atp2c2"
                     /gene_synonym="Spca2"
                     /inference="alignment:Splign:2.1.0"
     exon            1406..1495
                     /gene="Atp2c2"
                     /gene_synonym="Spca2"
                     /inference="alignment:Splign:2.1.0"
     exon            1496..1597
                     /gene="Atp2c2"
                     /gene_synonym="Spca2"
                     /inference="alignment:Splign:2.1.0"
     exon            1598..1754
                     /gene="Atp2c2"
                     /gene_synonym="Spca2"
                     /inference="alignment:Splign:2.1.0"
     exon            1755..1925
                     /gene="Atp2c2"
                     /gene_synonym="Spca2"
                     /inference="alignment:Splign:2.1.0"
     exon            1926..2023
                     /gene="Atp2c2"
                     /gene_synonym="Spca2"
                     /inference="alignment:Splign:2.1.0"
     exon            2024..2074
                     /gene="Atp2c2"
                     /gene_synonym="Spca2"
                     /inference="alignment:Splign:2.1.0"
     exon            2075..2241
                     /gene="Atp2c2"
                     /gene_synonym="Spca2"
                     /inference="alignment:Splign:2.1.0"
     exon            2242..2310
                     /gene="Atp2c2"
                     /gene_synonym="Spca2"
                     /inference="alignment:Splign:2.1.0"
     exon            2311..2427
                     /gene="Atp2c2"
                     /gene_synonym="Spca2"
                     /inference="alignment:Splign:2.1.0"
     exon            2428..2575
                     /gene="Atp2c2"
                     /gene_synonym="Spca2"
                     /inference="alignment:Splign:2.1.0"
     exon            2576..2674
                     /gene="Atp2c2"
                     /gene_synonym="Spca2"
                     /inference="alignment:Splign:2.1.0"
     exon            2675..2816
                     /gene="Atp2c2"
                     /gene_synonym="Spca2"
                     /inference="alignment:Splign:2.1.0"
     exon            2817..3116
                     /gene="Atp2c2"
                     /gene_synonym="Spca2"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cgcagcacca gccgcggcct cgctagggcc ccagggaagc gggctgggac tacgacctgc
       61 cccacgcccg gctgtggagc agcctggaca ccagctcacc atggggagac gcttcaagtt
      121 tctgcagaaa ctggccttct tgggccagaa ccaccggtac aaggcgctag aaagggacga
      181 ggtggacacc ctgattgatg aacagtacga gctgaaagct atcgaaagag aaaaggcagt
      241 cgctgccctg ccacccaggg aagcgtgcaa atgcagcaag gaggagttgg ccagaacctt
      301 ccacgtggac ctggacagcg gcctgtcaga atttgcagta gcccagcgta ggctggtcca
      361 tggctggaac gagtttgtca ctgataacac tgagcctgtg tggaagaaat acctggatca
      421 gttcaggaac cccctgatcc tgctgctgct gggctcatcc gtggtgagcg tcctcaccaa
      481 agagtatgaa gacgccatca gcattgccct ggccgtcctc atcgtggtga ctgttggctt
      541 catccaggag tacaggtcgg agaagtctct ggaagagctc accaagctag tacctccaga
      601 gtgcaactgc ctgagagacg gcaagctccg gcacatgctc gcccgagacc tggttccagg
      661 agacgttgtg tccttgtcca tgggagaccg gatccctgcc gatatccgac tcactgaggt
      721 cacagatctc ctggtggatg aatccagctt cacaggagaa gtggagccat gcagcaaaac
      781 agacagccca ttggcgggcg gcggggatct cagcaccctg agcaacgtgg tcttcatggg
      841 gacgctggtg cagtgcggga agggtcaggg ggtcgtgatc ggaaccgggg agcagtctca
      901 gtttggagaa gtttttaaga tgatgcgggc agaagagaca cctaaaactc cattacagaa
      961 gagcatggac aagctaggca agcaactgac cgtcttttcc tttggcatca tcggtctcct
     1021 gatgctggtt ggctgggtgc aggggaaacc ccttctcagc atgttcacta tcggggtcag
     1081 tctagctgtg gcggccattc cagaggggct gcccatcgtt gtcatggtga cgctggtcct
     1141 gggggtgctg cggatggcta agaagcgggt catcgtgaag aagctgccca ttgtagagac
     1201 tctcggttgc tgtaacgtca tctgctctga caagactggc actctgacag ccaacgaaat
     1261 gacagcaacc cagcttgtca cgtccgatgg cttccatgcc gaggtcagtg gcattggata
     1321 cagtggcgaa gggactgtgt gtcttctgcc ctccaaggaa gtaatcaaag aattcagcaa
     1381 tgtgtcagtg gggaagctgg tggaggcagg ctgcgtcgcc aacaacgctg tcgtcaggaa
     1441 gaacgccgta atggggcagc ccacagaagg ggccttggtg gtgctggcca tgaagatgaa
     1501 cttaggcagc atcaaagatt cctacatacg gaagaaggaa attcccttca gctcggagca
     1561 gaagtggatg gcagtgaggt gcagcctgaa gaatgaggat gaggaagatg tttacttcat
     1621 gaagggagcc tttgaggaag tgatccatca ctgcagcacg tataacaatg ggggcatccc
     1681 actgcctctg acaccccagc agaagtccta ttgccagcag gaagagaaga agatggggtc
     1741 gctcggcctt cgggtgctgg ccctggcgtc tggacctgag ctgggaaggc tgacattcct
     1801 cggtctggtg ggcatcatcg accccccaag ggctggcgtg aaggaagcgg tccaggccct
     1861 ctcggagtct gatgtgtcag ttaagatggt gacaggggat gctctggaga ctgccttggc
     1921 cataggaaga accatcggcc tgtgcgacga gaagctgaaa gctatgtccg gggaggaggt
     1981 ggagggcatg gagcaggacg cactggcagc ccgagtgagg caggtgtctg tattcttcag
     2041 gaccagccca aagcacaagg ttaaaatcat aaaggcattg caggagtcgg gggcaattgt
     2101 agccatgacg ggggatggag tgaatgactc agttgccctg aagtctgcgg acatcgggat
     2161 tgccatggga cagacaggaa cagacgtcag caaagaggcc gctgacatga ttctggtgga
     2221 cgacgacttc tcggccatta tgagtgcagt ggaggaaggt aagggcatct tctacaacat
     2281 caagaacttt gtccgcttcc agctgagcac gagcatcgca gccctgagcc tcatcaccct
     2341 gtccaccgtg tgcaacctgc ccaaccccct caatgccatg cagatcctgt gggtgaacat
     2401 catcatggac ggaccaccgg cccagagcct aggggtggaa cctgtggaca gagatgccct
     2461 gaagaggcct cctcggagcg tcaaggacac gatcctgaac agagccctga tcctgaagat
     2521 cctcatgtcg gctgctgtta tcttaggggg gaccctgttc atcttctgga gagagatccc
     2581 agagaaccgt accagcaccc cacgcaccac caccatggcc ttcacctgct tcgtgttttt
     2641 cgacctcttc aatgctctaa gctgccgctc tcagaccaag ctgatatttg agattggctt
     2701 tttccggaac cgcatgttcc tgtactcgat ccttgggtcc ctcctcgggc agctggccgt
     2761 gatctatgcc ccgcccttgc agaaggtctt ccagaccgaa aacctgagcg cgctcgacct
     2821 gctgctgctg actggcctgg cctcgtccgt cttcatcttg tccgagctgc tcaagctatg
     2881 tgaaaagttc tgctccagag ccaaggctga tcagatgctc ccggaggccg tgtaaaggaa
     2941 ccagggtgtc atggctgact gacttgtgtc cttgggtgcc tctggcctgg ccccgtcctt
     3001 ctgcactatc tgctccaaga ggcagatttt aggactgtgc agcatcctgc acaggacagg
     3061 gtggagctta tactgaaaca tggcgctatt tattaaacca ccgtggtttt tattta
//
