LOCUS       NM_001170482             450 bp    mRNA    linear   ROD 31-MAR-2024
DEFINITION  Rattus norvegicus atonal bHLH transcription factor 7 (Atoh7), mRNA.
ACCESSION   NM_001170482 XM_001080515 XM_345102
VERSION     NM_001170482.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 450)
  AUTHORS   Zeng,Q., Zhou,J. and Hua,X.
  TITLE     TRIM9 promotes Muller cell-derived retinal stem cells to
            differentiate into retinal ganglion cells by regulating Atoh7
  JOURNAL   In Vitro Cell Dev Biol Anim 59 (8), 586-595 (2023)
   PUBMED   37792226
  REMARK    GeneRIF: TRIM9 promotes Muller cell-derived retinal stem cells to
            differentiate into retinal ganglion cells by regulating Atoh7.
REFERENCE   2  (bases 1 to 450)
  AUTHORS   Song,W.T., Zhang,X.Y. and Xia,X.B.
  TITLE     Atoh7 promotes the differentiation of Muller cells-derived retinal
            stem cells into retinal ganglion cells in a rat model of glaucoma
  JOURNAL   Exp Biol Med (Maywood) 240 (5), 682-690 (2015)
   PUBMED   25710928
  REMARK    GeneRIF: Atoh7 promotes the differentiation of Muller cells-derived
            retinal stem cells into retinal ganglion cells in a rat model of
            glaucoma, thus opening up a new avenue for gene therapy and optic
            nerve regeneration in glaucoma
REFERENCE   3  (bases 1 to 450)
  AUTHORS   Ghiasvand,N.M., Rudolph,D.D., Mashayekhi,M., Brzezinski,J.A. 4th,
            Goldman,D. and Glaser,T.
  TITLE     Deletion of a remote enhancer near ATOH7 disrupts retinal
            neurogenesis, causing NCRNA disease
  JOURNAL   Nat Neurosci 14 (5), 578-586 (2011)
   PUBMED   21441919
REFERENCE   4  (bases 1 to 450)
  AUTHORS   Wee,R., Castrucci,A.M., Provencio,I., Gan,L. and Van Gelder,R.N.
  TITLE     Loss of photic entrainment and altered free-running circadian
            rhythms in math5-/- mice
  JOURNAL   J Neurosci 22 (23), 10427-10433 (2002)
   PUBMED   12451142
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000020.1.
            
            On or before Dec 20, 2009 this sequence version replaced
            XM_345102.2, XM_001080515.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-450               JAXUCZ010000020.1  25529528-25529977   c
FEATURES             Location/Qualifiers
     source          1..450
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="20"
                     /map="20p11"
     gene            1..450
                     /gene="Atoh7"
                     /note="atonal bHLH transcription factor 7"
                     /db_xref="GeneID:365564"
                     /db_xref="RGD:1304957"
     CDS             1..450
                     /gene="Atoh7"
                     /note="atonal homolog 7"
                     /codon_start=1
                     /product="transcription factor ATOH7"
                     /protein_id="NP_001163953.1"
                     /db_xref="GeneID:365564"
                     /db_xref="RGD:1304957"
                     /translation="MKSACKPHGPPAGARGAPPCAGAAERAVSCAGPGRLESAARRRL
                     AANARERRRMQGLNTAFDRLRRVVPQWGQDKKLSKYETLQMALSYIVALTRILAEAER
                     DWVGLRCEQRGRNHPYLPFPGARLQVDPEPYGQKFFGFQPESFPMAS"
     exon            1..450
                     /gene="Atoh7"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 atgaagtccg cctgcaaacc ccacggtcct ccggcgggag cacgcggcgc gcccccgtgc
       61 gcgggcgcag ccgagcgcgc ggtctcctgc gcggggcccg ggcggctgga aagcgcagcg
      121 cgcaggcgcc tggcggccaa cgcgcgcgag cggcgccgca tgcaagggct gaacaccgcg
      181 ttcgaccggc tgcgcagggt ggtgccgcaa tggggccagg acaagaagct gtccaagtac
      241 gagacactgc agatggcgct cagctacatc gtggcgctca cccgcatcct agccgaagcc
      301 gagcgggact gggtggggct gcgctgcgag cagcggggcc gcaatcaccc ctacctccca
      361 ttccccggtg ctaggctcca ggtagaccct gagccctacg ggcagaagtt cttcggtttc
      421 cagccagagt ccttccccat ggccagctaa
//
