LOCUS       NM_001271114            1245 bp    mRNA    linear   ROD 31-MAR-2024
DEFINITION  Rattus norvegicus autophagy related 101 (Atg101), transcript
            variant 2, mRNA.
ACCESSION   NM_001271114
VERSION     NM_001271114.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1245)
  AUTHORS   Zhang,Z.J., Wang,K.P., Huang,Y.P., Jin,C., Jiang,H., Xiong,L.,
            Chen,Z.Y., Wen,Y., Liu,Z.T. and Mo,J.G.
  TITLE     Comprehensive Analysis of the Potential Immune-Related Biomarker
            ATG101 that Regulates Apoptosis of Cholangiocarcinoma Cells After
            Photodynamic Therapy
  JOURNAL   Front Pharmacol 13, 857774 (2022)
   PUBMED   35592424
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1245)
  AUTHORS   Wang,Y., Lin,K., Xu,T., Wang,L., Fu,L., Zhang,G., Ai,J., Jiao,Y.,
            Zhu,R., Han,X. and Cai,H.
  TITLE     Development and validation of prognostic model based on the
            analysis of autophagy-related genes in colon cancer
  JOURNAL   Aging (Albany NY) 13 (14), 19028-19047 (2021)
   PUBMED   34315829
REFERENCE   3  (bases 1 to 1245)
  AUTHORS   Behrends,C., Sowa,M.E., Gygi,S.P. and Harper,J.W.
  TITLE     Network organization of the human autophagy system
  JOURNAL   Nature 466 (7302), 68-76 (2010)
   PUBMED   20562859
REFERENCE   4  (bases 1 to 1245)
  AUTHORS   Hosokawa,N., Sasaki,T., Iemura,S., Natsume,T., Hara,T. and
            Mizushima,N.
  TITLE     Atg101, a novel mammalian autophagy protein interacting with Atg13
  JOURNAL   Autophagy 5 (7), 973-979 (2009)
   PUBMED   19597335
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000007.1 and BU670996.1.
            
            Transcript Variant: This variant (2) differs in the 5' UTR and
            lacks a portion of the 5' coding region compared to variant 1.
            These differences cause translation initiation at a downstream AUG
            and result in an isoform (2) with a shorter N-terminus, compared to
            isoform 1.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data because no single transcript from the same
            strain was available for the full length of the gene. The extent of
            this transcript is supported by {transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: DY553592.1, CF109006.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760386
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-28                JAXUCZ010000007.1  134277245-134277272
            29-669              BU670996.1         1-641
            670-1245            JAXUCZ010000007.1  134285812-134286387
FEATURES             Location/Qualifiers
     source          1..1245
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="7"
                     /map="7q36"
     gene            1..1245
                     /gene="Atg101"
                     /gene_synonym="RGD1359310"
                     /note="autophagy related 101"
                     /db_xref="GeneID:300240"
                     /db_xref="RGD:1359310"
     exon            1..252
                     /gene="Atg101"
                     /gene_synonym="RGD1359310"
                     /inference="alignment:Splign:2.1.0"
     exon            253..566
                     /gene="Atg101"
                     /gene_synonym="RGD1359310"
                     /inference="alignment:Splign:2.1.0"
     CDS             315..971
                     /gene="Atg101"
                     /gene_synonym="RGD1359310"
                     /note="isoform 2 is encoded by transcript variant 2;
                     autophagy-related protein 101"
                     /codon_start=1
                     /product="autophagy-related protein 101 isoform 2"
                     /protein_id="NP_001258043.1"
                     /db_xref="GeneID:300240"
                     /db_xref="RGD:1359310"
                     /translation="MNCRSEVLEVSVEGRQVEEAMLAVLHTVLLHRSTGKFHYKKEGT
                     YSIGTVGIQDVDCDFIDFTYVRVSSEELDRALRKVVGEFKDALRNSGGDGLGQMSLEF
                     YQKKKSRWPFSDECIPWEVWTVKVHVVALATEQERQICREKVGEKLCEKIINIVEVMS
                     RHEYLPKMPTQSELDNVFDTGLRDVQPYLYKISFQITEALGTSVTTTMRRLIKDTLAL
                     "
     exon            567..1245
                     /gene="Atg101"
                     /gene_synonym="RGD1359310"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cgccgctcag gcggagggag cggtggactg gacgggcgtc tgtagcgttt ggaccccgtc
       61 ctcatcttct gcgctgctgc cccgagacgg cgcgaggtct cgggcggtga ccctgacgtc
      121 ttgtccgaat tctcggtacg gatccaaata ccctgttttt gcttttggtc tgtccctgaa
      181 tactccgtgt tcgcgctagg gaagaagagg actcgaggcc gagtggctcc ggctgggatt
      241 cctaccagca aggttggccc ctacgtgggg tgaagcgtct tgtctctcgc ctttgctcca
      301 gctctagctg caggatgaac tgtcgatcag aagtgctgga ggtgtcggtg gaggggcggc
      361 aggtggagga ggccatgctg gccgtgctgc acacagtgct gcttcaccgc agcacaggca
      421 agtttcacta caagaaggag ggcacgtact ccatcggcac cgtgggcatc caggatgtag
      481 actgtgactt catcgacttc acatatgtgc gtgtctcctc cgaggagctg gaccgcgcct
      541 tgcgcaaggt tgttggggaa ttcaaggatg cactgcggaa ctcaggcggc gatgggctgg
      601 gccagatgtc cttggaattc taccagaaga agaagtctcg ctggcctttt tcggatgagt
      661 gcatcccctg ggaggtgtgg actgtcaagg tgcacgtggt agccctggcc acagagcagg
      721 agcggcagat ctgcagagag aaggtgggag agaagctgtg tgagaagatt atcaacatcg
      781 tggaggtgat gagccggcac gagtacctgc ccaagatgcc cactcagtca gagctggaca
      841 acgtgtttga cacgggcttg cgggacgtgc agccctacct ctacaagatc tcctttcaga
      901 tcaccgaggc cctgggcacc tcagtcacca ccactatgcg caggctcatc aaagacaccc
      961 ttgccctata ggccttgccg ggccttggca gctccttaat ggttctggag tgggttgctg
     1021 ggatctcagg gttcttgaac ctgctctaga tccttggtga gacttgaaga ggagctcttg
     1081 gtgtccttgt tttgtggttg ccagcctctg gtgaccctgt cacctttgca gtgacgtggt
     1141 cctgggtgta gcctttgcgc ctgctctggt ggggtttgct ttctacactg tacagttcta
     1201 ctgtgagggt gcggaataaa gttgaggtgt gagtttgtct tggtt
//
