LOCUS       NM_001109505            1590 bp    mRNA    linear   ROD 26-FEB-2024
DEFINITION  Rattus norvegicus autophagy related 10 (Atg10), mRNA.
ACCESSION   NM_001109505 XM_001067400
VERSION     NM_001109505.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1590)
  AUTHORS   Radoshevich L, Murrow L, Chen N, Fernandez E, Roy S, Fung C and
            Debnath J.
  TITLE     ATG12 conjugation to ATG3 regulates mitochondrial homeostasis and
            cell death
  JOURNAL   Cell 142 (4), 590-600 (2010)
   PUBMED   20723759
REFERENCE   2  (bases 1 to 1590)
  AUTHORS   Yang Z and Klionsky DJ.
  TITLE     Mammalian autophagy: core molecular machinery and signaling
            regulation
  JOURNAL   Curr Opin Cell Biol 22 (2), 124-131 (2010)
   PUBMED   20034776
  REMARK    Review article
REFERENCE   3  (bases 1 to 1590)
  AUTHORS   Criollo A, Maiuri MC, Tasdemir E, Vitale I, Fiebig AA, Andrews D,
            Molgo J, Diaz J, Lavandero S, Harper F, Pierron G, di Stefano D,
            Rizzuto R, Szabadkai G and Kroemer G.
  TITLE     Regulation of autophagy by the inositol trisphosphate receptor
  JOURNAL   Cell Death Differ 14 (5), 1029-1039 (2007)
   PUBMED   17256008
REFERENCE   4  (bases 1 to 1590)
  AUTHORS   Shao Y, Gao Z, Feldman T and Jiang X.
  TITLE     Stimulation of ATG12-ATG5 conjugation by ribonucleic acid
  JOURNAL   Autophagy 3 (1), 10-16 (2007)
   PUBMED   16963840
REFERENCE   5  (bases 1 to 1590)
  AUTHORS   Boya P, Gonzalez-Polo RA, Casares N, Perfettini JL, Dessen P,
            Larochette N, Metivier D, Meley D, Souquere S, Yoshimori T, Pierron
            G, Codogno P and Kroemer G.
  TITLE     Inhibition of macroautophagy triggers apoptosis
  JOURNAL   Mol Cell Biol 25 (3), 1025-1040 (2005)
   PUBMED   15657430
REFERENCE   6  (bases 1 to 1590)
  AUTHORS   Tanida I, Ueno T and Kominami E.
  TITLE     LC3 conjugation system in mammalian autophagy
  JOURNAL   Int J Biochem Cell Biol 36 (12), 2503-2518 (2004)
   PUBMED   15325588
  REMARK    Review article
REFERENCE   7  (bases 1 to 1590)
  AUTHORS   Nemoto T, Tanida I, Tanida-Miyake E, Minematsu-Ikeguchi N, Yokota
            M, Ohsumi M, Ueno T and Kominami E.
  TITLE     The mouse APG10 homologue, an E2-like enzyme for Apg12p
            conjugation, facilitates MAP-LC3 modification
  JOURNAL   J Biol Chem 278 (41), 39517-39526 (2003)
   PUBMED   12890687
REFERENCE   8  (bases 1 to 1590)
  AUTHORS   Mizushima N, Yoshimori T and Ohsumi Y.
  TITLE     Mouse Apg10 as an Apg12-conjugating enzyme: analysis by the
            conjugation-mediated yeast two-hybrid method
  JOURNAL   FEBS Lett 532 (3), 450-454 (2002)
   PUBMED   12482611
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH473955.1.
            
            [WARNING] On Apr 10, 2024 this sequence was replaced by
            NM_001109505.2.
            
            On Oct 4, 2007 this sequence version replaced XM_001067400.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: FM088345.1, SRR8487227.39951.1
                                           [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMD00132261,
                                           SAMD00132262 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1590
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="2"
                     /map="2q12"
     gene            1..1590
                     /gene="Atg10"
                     /note="autophagy related 10"
                     /db_xref="GeneID:688555"
                     /db_xref="RGD:1587624"
     exon            1..31
                     /gene="Atg10"
                     /inference="alignment:Splign:2.1.0"
     exon            32..148
                     /gene="Atg10"
                     /inference="alignment:Splign:2.1.0"
     CDS             44..688
                     /gene="Atg10"
                     /note="autophagy-related protein 10; autophagy related 10
                     homolog"
                     /codon_start=1
                     /product="ubiquitin-like-conjugating enzyme ATG10"
                     /protein_id="NP_001102975.1"
                     /db_xref="GeneID:688555"
                     /db_xref="RGD:1587624"
                     /translation="MEDEFFGEESFQHCCAEFIRHSQQIGDGWEWRTAKECSDGYMCK
                     TQFQIKKETPTPHRETPASVHTCLPTEENLELPVDDSEAVGPAAAAVIRQEYHVLYSC
                     SYQVPVLYFRASFLDGRPLALEDIWEGVHECYKLRLLQGPWDTITQQEHPILGQPFFV
                     LHPCKTNEFMTAVLKNSQKINRNVNYITSWLSIVGPVVGLNLPLSYAKATSQSE"
     exon            149..256
                     /gene="Atg10"
                     /inference="alignment:Splign:2.1.0"
     exon            257..392
                     /gene="Atg10"
                     /inference="alignment:Splign:2.1.0"
     exon            393..490
                     /gene="Atg10"
                     /inference="alignment:Splign:2.1.0"
     exon            491..588
                     /gene="Atg10"
                     /inference="alignment:Splign:2.1.0"
     exon            589..704
                     /gene="Atg10"
                     /inference="alignment:Splign:2.1.0"
     exon            705..1590
                     /gene="Atg10"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cgccggctcc aggtcagggc gagcgagcgg gttcccattt aacatggagg acgagttctt
       61 tggagaagaa agcttccaac attgttgtgc agaattcatc agacattcac aacagatagg
      121 cgatggctgg gaatggagaa cggccaagga atgttctgat ggctacatgt gcaaaacaca
      181 gtttcaaata aagaaagaga ctccaacacc acatcgggaa acacccgcca gtgtgcacac
      241 gtgtctcccc acagaggaga acttggagct accagtggat gattctgaag ccgtggggcc
      301 tgcggcggcg gcagtgatta gacaggagta tcatgtctta tactcctgta gctaccaagt
      361 gcccgttctg tactttaggg caagcttttt agatgggaga cctttagctc tggaggatat
      421 atgggaagga gtccatgaat gctataagct gcggctgctc cagggaccgt gggataccat
      481 cacccagcag gagcatccaa tacttgggca accatttttt gttctacatc cctgcaagac
      541 aaatgaattc atgactgctg tgctaaagaa ttcacagaaa atcaatagaa atgtcaacta
      601 catcacatca tggctgagca tcgtgggacc agttgttggt ctgaatttac ctctgagcta
      661 cgccaaagca acatcacaat ctgagtgatc tgtgaacaag caagatctgc tgatcctaga
      721 aactgcagca tgaaggatag caagagctct gcctgggaag cctcagcttt catggaaatg
      781 ggactgcagt atctcatgtc accaagattt gatgcggagt tctttcctca gaaagaagac
      841 atctgcaaaa cctgtttgct tgggatagtg gttgtatgga aggaacaagt cacggattca
      901 gatcactata aacaacaaag atgaacctat ttcagtggtg atgtcattgc tggcatcatc
      961 aaggctcaca caggttcttt ttgccttggc acagttcttc tgttgtggag attgatgggg
     1021 aagtatattt gtgtgcttgc tttagtgtac aatgtgtgaa aattaaaatg tagaacttgc
     1081 ctgtttctga aaattaatgt tatacatttg acccatctta aattattctc caacagtcaa
     1141 actcaggagc aatgggttat ttctcaatta ctcaccaaaa aaaaaaaaaa aaagtgtgtg
     1201 tgtgtgtgtg tgtgtgtgtg tgtgtgtaca tagaaaatta gatacagaat aaagaataac
     1261 tgatcatttt aatataatga tgtattttac aagccaggta tagaaaggta actacaggtt
     1321 tttaaaatag ctataaaaaa cattcaagca ttgcaaatgc ttttttttta ataaaaataa
     1381 cacagttgtt tttccttcta tgtgtgagac ccatgactgt tctgctgcaa tactgcaggc
     1441 ttttgtgtaa gtcttcatag ccctacaatg ttctttctaa tatgagaata acaagctgtc
     1501 tcataatgtt gctgtgagaa ctatatgaag tcattaacac acaactattg aaacacgtat
     1561 acaaatatta attaaatgtt cacctgctgc
//
