LOCUS       NM_001002809            2507 bp    mRNA    linear   ROD 26-FEB-2024
DEFINITION  Rattus norvegicus activating transcription factor 6 beta (Atf6b),
            mRNA.
ACCESSION   NM_001002809 XM_579083
VERSION     NM_001002809.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2507)
  AUTHORS   Abonnenc M, Nabeebaccus AA, Mayr U, Barallobre-Barreiro J, Dong X,
            Cuello F, Sur S, Drozdov I, Langley SR, Lu R, Stathopoulou K,
            Didangelos A, Yin X, Zimmermann WH, Shah AM, Zampetaki A and Mayr
            M.
  TITLE     Extracellular matrix secretion by cardiac fibroblasts: role of
            microRNA-29b and microRNA-30c
  JOURNAL   Circ Res 113 (10), 1138-1147 (2013)
   PUBMED   24006456
REFERENCE   2  (bases 1 to 2507)
  AUTHORS   Thuerauf DJ, Morrison L and Glembotski CC.
  TITLE     Opposing roles for ATF6alpha and ATF6beta in endoplasmic reticulum
            stress response gene induction
  JOURNAL   J Biol Chem 279 (20), 21078-21084 (2004)
   PUBMED   14973138
REFERENCE   3  (bases 1 to 2507)
  AUTHORS   Haze K, Okada T, Yoshida H, Yanagi H, Yura T, Negishi M and Mori K.
  TITLE     Identification of the G13 (cAMP-response-element-binding
            protein-related protein) gene product related to activating
            transcription factor 6 as a transcriptional activator of the
            mammalian unfolded protein response
  JOURNAL   Biochem J 355 (Pt 1), 19-28 (2001)
   PUBMED   11256944
REFERENCE   4  (bases 1 to 2507)
  AUTHORS   Yoshida H, Haze K, Yanagi H, Yura T and Mori K.
  TITLE     Identification of the cis-acting endoplasmic reticulum stress
            response element responsible for transcriptional induction of
            mammalian glucose-regulated proteins. Involvement of basic leucine
            zipper transcription factors
  JOURNAL   J Biol Chem 273 (50), 33741-33749 (1998)
   PUBMED   9837962
  REMARK    Erratum:[J Biol Chem 1999 Jan 22;274(4):2592]
REFERENCE   5  (bases 1 to 2507)
  AUTHORS   Khanna A and Campbell RD.
  TITLE     The gene G13 in the class III region of the human MHC encodes a
            potential DNA-binding protein
  JOURNAL   Biochem J 319 (Pt 1) (Pt 1), 81-89 (1996)
   PUBMED   8870652
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            FM061416.1, BC098631.1 and BP486278.1.
            
            On Sep 28, 2009 this sequence version replaced NM_001002809.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC098631.1, SRR8487226.181880.1
                                           [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMD00132261,
                                           SAMD00132262 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-9                 FM061416.1         1-9
            10-2503             BC098631.1         1-2494
            2504-2507           BP486278.1         1-4                 c
FEATURES             Location/Qualifiers
     source          1..2507
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="20"
                     /map="20p12"
     gene            1..2507
                     /gene="Atf6b"
                     /gene_synonym="Crebl1"
                     /note="activating transcription factor 6 beta"
                     /db_xref="GeneID:406169"
                     /db_xref="RGD:1303317"
     exon            1..98
                     /gene="Atf6b"
                     /gene_synonym="Crebl1"
                     /inference="alignment:Splign:2.1.0"
     CDS             17..2128
                     /gene="Atf6b"
                     /gene_synonym="Crebl1"
                     /note="cAMP responsive element binding protein-like 1"
                     /codon_start=1
                     /product="cyclic AMP-dependent transcription factor ATF-6
                     beta"
                     /protein_id="NP_001002809.2"
                     /db_xref="GeneID:406169"
                     /db_xref="RGD:1303317"
                     /translation="MAELMLLSEIADPTRFFTDNLLSPEDWDSTLYSGLDEVAEEQTQ
                     LFRCVEQDVPFDSSSLDVGMDVIPPEPPWDPLPIFPDLQVKSEPSSPCSSSSLSSESS
                     HLSTEPSSQVPRVGEVLQVKMESLAPPLCLLGDDPAFPFETVQITVGSASDDLADIQT
                     KLEPASPSSSVNSEASLLSADSPSQALIGEEVLEVKTESPSPPGCLLWDVPASSLGAV
                     QISMGPSPDSSSGKAPAPRKPPLQPKPVVLTTVPVPPRAGPASTAVLLQPLVQQPAVS
                     PVVLIQGAIRAQPEGPAPAAPRPERKSIVPAPMPGNACPPEVDAKLLKRQQRMIKNRE
                     SACQSRRKKKEYLQGLEARLQAVLADNQQLRRENAALRRRLEALLAENSELKLGSGNR
                     KVVCIMVFLLFIAFNFGPVSISEPPPAPVSRMSREGPRPQRHLLGFSEPGPAHGIEPL
                     QEAAKGPEEQQPSPAGKPSFRNLTAFPSGAKELLLRDLDQLFLSSDCRHFNRTESLRL
                     ADELSGWVQRHQRGHQRGRRKIPHRAQERQKSQLRKKSPPVKPVPTQPPGPPERDPVG
                     QLQLYRHPGRSQPEFLDAIDRREDTFYVVSFRRDHLLLPAISHNKTSRPKMSLVMPAM
                     APNETVSGRGPAGDYEEMMQIECEVMDTRVIHIKTSTVPPSLRKQPSPSPGNTTGGPL
                     PGSAASPARQASRQPLYLNHP"
     exon            99..178
                     /gene="Atf6b"
                     /gene_synonym="Crebl1"
                     /inference="alignment:Splign:2.1.0"
     exon            179..257
                     /gene="Atf6b"
                     /gene_synonym="Crebl1"
                     /inference="alignment:Splign:2.1.0"
     exon            258..349
                     /gene="Atf6b"
                     /gene_synonym="Crebl1"
                     /inference="alignment:Splign:2.1.0"
     exon            350..485
                     /gene="Atf6b"
                     /gene_synonym="Crebl1"
                     /inference="alignment:Splign:2.1.0"
     exon            486..571
                     /gene="Atf6b"
                     /gene_synonym="Crebl1"
                     /inference="alignment:Splign:2.1.0"
     exon            572..707
                     /gene="Atf6b"
                     /gene_synonym="Crebl1"
                     /inference="alignment:Splign:2.1.0"
     exon            708..973
                     /gene="Atf6b"
                     /gene_synonym="Crebl1"
                     /inference="alignment:Splign:2.1.0"
     exon            974..1159
                     /gene="Atf6b"
                     /gene_synonym="Crebl1"
                     /inference="alignment:Splign:2.1.0"
     exon            1160..1251
                     /gene="Atf6b"
                     /gene_synonym="Crebl1"
                     /inference="alignment:Splign:2.1.0"
     exon            1252..1428
                     /gene="Atf6b"
                     /gene_synonym="Crebl1"
                     /inference="alignment:Splign:2.1.0"
     exon            1429..1536
                     /gene="Atf6b"
                     /gene_synonym="Crebl1"
                     /inference="alignment:Splign:2.1.0"
     exon            1537..1630
                     /gene="Atf6b"
                     /gene_synonym="Crebl1"
                     /inference="alignment:Splign:2.1.0"
     exon            1631..1701
                     /gene="Atf6b"
                     /gene_synonym="Crebl1"
                     /inference="alignment:Splign:2.1.0"
     exon            1702..1813
                     /gene="Atf6b"
                     /gene_synonym="Crebl1"
                     /inference="alignment:Splign:2.1.0"
     exon            1814..1898
                     /gene="Atf6b"
                     /gene_synonym="Crebl1"
                     /inference="alignment:Splign:2.1.0"
     exon            1899..2507
                     /gene="Atf6b"
                     /gene_synonym="Crebl1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ggggggtggg gggaagatgg cggagctgat gctcctcagc gagatcgccg acccgacgcg
       61 cttcttcacc gacaacctgc tgagtccgga ggactgggac agcaccttgt acagtggcct
      121 ggatgaagtg gccgaggagc agacgcagtt gtttcgttgc gtggagcagg atgtcccgtt
      181 tgacagcagc tctctggatg tggggatgga tgtcatcccc cctgagcccc cttgggaccc
      241 tctacccatc ttcccagatc ttcaggtgaa gtctgagccg tcctctccct gctcctcttc
      301 ctccctcagc tcagaatcct cacatctttc cacagagccc tccagccagg ttcctagagt
      361 aggggaggtg ctgcaggtaa agatggagtc cctggcaccc ccgctctgcc tgctgggaga
      421 tgatccagcg ttcccctttg aaacagtcca gatcactgtg ggctctgcct ctgatgatct
      481 cgcagatatc cagaccaagc tagaacccgc ctctccgtct tcctctgtca actccgaggc
      541 ctccttgctg tcagcagact ctcccagcca ggctcttata ggagaggagg ttctggaagt
      601 gaagacagag tctccgtccc ctccagggtg cctcctctgg gatgtcccag cctcttcact
      661 tggagctgtc cagatcagca tgggtccgtc ccctgatagt tcctcaggga aagctcctgc
      721 ccctcggaag cctccactgc agcccaagcc tgtggtgcta accacagttc cggtgccacc
      781 tagagctggg cctgccagca ctgctgtcct tctgcagccc ctggtccagc agcccgcagt
      841 atccccggtg gttctcatcc aaggtgctat ccgagcccag cctgaagggc cagctccggc
      901 agcccctcgg cctgagagga agagcattgt cccagcccct atgccgggga acgcctgccc
      961 gcctgaagtg gacgcgaagc tgctaaagcg ccagcagcgg atgatcaaga accgggagtc
     1021 agcctgccag tcccgccgca agaagaagga gtacctgcaa ggcctggagg cccggctgca
     1081 ggccgtgctg gccgacaacc agcagctgcg ccgggagaat gctgccctcc ggcggcggct
     1141 ggaggcccta ctggcagaga acagcgagct caagctgggg tctggaaaca ggaaggttgt
     1201 ctgcatcatg gtcttccttc tcttcattgc cttcaacttt gggcctgtca gcatcagcga
     1261 gccacctcca gctcccgtct ctcggatgag cagggaggga ccccgacccc agaggcacct
     1321 gctggggttc tcagaaccag ggccagctca cggcatcgaa cccctccagg aagctgccaa
     1381 gggccctgag gagcagcagc ccagccctgc aggcaagccc agcttcagaa acctgacagc
     1441 cttccccagt ggggccaagg agctgctgct gagagacctg gaccagctct tcctttcctc
     1501 tgactgccgc catttcaacc gaactgagtc tctgaggctt gctgatgagc tgagtggctg
     1561 ggtccaacgt caccagagag gtcaccagag aggtcgtcgg aagatacctc atagggccca
     1621 ggagagacag aagtctcagc tacggaagaa gtcccctcca gtgaaaccag tccccaccca
     1681 acctccagga ccccctgaaa gggaccccgt gggccagctg cagctctacc gccacccagg
     1741 ccgctcacag ccggagtttc tagatgcaat tgaccggagg gaagatacct tctatgttgt
     1801 ctccttccga agggaccact tgctgctccc agccatcagc cacaacaaga catccaggcc
     1861 caagatgtcg ttggtgatgc cagccatggc ccccaatgag accgtgtcag gccgggggcc
     1921 cgctggggac tatgaggaga tgatgcagat tgagtgtgaa gtcatggaca ccagggtgat
     1981 tcacatcaag acctccacgg tgcccccctc acttcggaag cagccgtccc cgtccccagg
     2041 caataccaca ggtggcccct tgccaggctc cgcagccagt ccggcccgtc aggcctcccg
     2101 ccagcccctc tacctcaatc atccctgact tcttcagccc atattggctt agaaccgggt
     2161 tggggagcct gatcctgggg ctcggggcag ttggtaaagg aaggtggggt gtggggatta
     2221 agcacttggc gggacatggg tgggtggttc acctctcttc tcactctctc cggaatatag
     2281 agctcctctg gttcctgcac ccccagtcct ctttctccga gggcactgcg tgagggtggc
     2341 tcctgtaccc tcttctgtac ctgtaccttt atctattcgg gagtaaaggt gggacttggt
     2401 ccccaggtgg gacaagggat ggtctcgggt ggcacaaggc agttatgtgt gtgcatatct
     2461 tttttattat tattattaaa taaacaactt ggaggggtgt aaaggaa
//
