LOCUS       NM_001100895            2337 bp    mRNA    linear   ROD 23-MAR-2023
DEFINITION  Rattus norvegicus activating transcription factor 1 (Atf1), mRNA.
ACCESSION   NM_001100895 XM_001064437 XM_235657
VERSION     NM_001100895.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2337)
  AUTHORS   Ciani B, Bjelic S, Honnappa S, Jawhari H, Jaussi R, Payapilly A,
            Jowitt T, Steinmetz MO and Kammerer RA.
  TITLE     Molecular basis of coiled-coil oligomerization-state specificity
  JOURNAL   Proc Natl Acad Sci U S A 107 (46), 19850-19855 (2010)
   PUBMED   21045134
REFERENCE   2  (bases 1 to 2337)
  AUTHORS   Reinke AW, Grigoryan G and Keating AE.
  TITLE     Identification of bZIP interaction partners of viral proteins HBZ,
            MEQ, BZLF1, and K-bZIP using coiled-coil arrays
  JOURNAL   Biochemistry 49 (9), 1985-1997 (2010)
   PUBMED   20102225
REFERENCE   3  (bases 1 to 2337)
  AUTHORS   Wang X, Ward CJ, Harris PC and Torres VE.
  TITLE     Cyclic nucleotide signaling in polycystic kidney disease
  JOURNAL   Kidney Int 77 (2), 129-140 (2010)
   PUBMED   19924104
REFERENCE   4  (bases 1 to 2337)
  AUTHORS   Katsuyama M, Ozgur Cevik M, Arakawa N, Kakehi T, Nishinaka T, Iwata
            K, Ibi M, Matsuno K and Yabe-Nishimura C.
  TITLE     Myocyte enhancer factor 2B is involved in the inducible expression
            of NOX1/NADPH oxidase, a vascular superoxide-producing enzyme
  JOURNAL   FEBS J 274 (19), 5128-5136 (2007)
   PUBMED   17822438
REFERENCE   5  (bases 1 to 2337)
  AUTHORS   Matsuo N, Tanaka S, Gordon MK, Koch M, Yoshioka H and Ramirez F.
  TITLE     CREB-AP1 protein complexes regulate transcription of the collagen
            XXIV gene (Col24a1) in osteoblasts
  JOURNAL   J Biol Chem 281 (9), 5445-5452 (2006)
   PUBMED   16373341
REFERENCE   6  (bases 1 to 2337)
  AUTHORS   Zaman K, Ryu H, Hall D, O'Donovan K, Lin KI, Miller MP, Marquis JC,
            Baraban JM, Semenza GL and Ratan RR.
  TITLE     Protection from oxidative stress-induced apoptosis in cortical
            neuronal cultures by iron chelators is associated with enhanced DNA
            binding of hypoxia-inducible factor-1 and ATF-1/CREB and increased
            expression of glycolytic enzymes, p21(waf1/cip1), and
            erythropoietin
  JOURNAL   J Neurosci 19 (22), 9821-9830 (1999)
   PUBMED   10559391
REFERENCE   7  (bases 1 to 2337)
  AUTHORS   Jones LC and Scammell JG.
  TITLE     The cAMP-response element mediates induction of secretogranin II by
            CHX and FSK in GH4C1 cells
  JOURNAL   Am J Physiol 274 (4), E656-E664 (1998)
   PUBMED   9575827
REFERENCE   8  (bases 1 to 2337)
  AUTHORS   Shimomura A, Okamoto Y, Hirata Y, Kobayashi M, Kawakami K, Kiuchi
            K, Wakabayashi T and Hagiwara M.
  TITLE     Dominant negative ATF1 blocks cyclic AMP-induced neurite outgrowth
            in PC12D cells
  JOURNAL   J Neurochem 70 (3), 1029-1034 (1998)
   PUBMED   9489722
REFERENCE   9  (bases 1 to 2337)
  AUTHORS   Ji L, Mochon E, Arcinas M and Boxer LM.
  TITLE     CREB proteins function as positive regulators of the translocated
            bcl-2 allele in t(14;18) lymphomas
  JOURNAL   J Biol Chem 271 (37), 22687-22691 (1996)
   PUBMED   8798441
REFERENCE   10 (bases 1 to 2337)
  AUTHORS   Rehfuss RP, Walton KM, Loriaux MM and Goodman RH.
  TITLE     The cAMP-regulated enhancer-binding protein ATF-1 activates
            transcription in response to cAMP-dependent protein kinase A
  JOURNAL   J Biol Chem 266 (28), 18431-18434 (1991)
   PUBMED   1655749
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            CO565801.1, BC091222.1 and CN541536.1.
            
            On or before Nov 21, 2008 this sequence version replaced
            XM_235657.4, XM_001064437.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC091222.1, SRR8487227.102381.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132261, SAMD00132262
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-26                CO565801.1         1-26
            27-2317             BC091222.1         1-2291
            2318-2337           CN541536.1         1-20                c
FEATURES             Location/Qualifiers
     source          1..2337
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="Sprague-Dawley"
                     /db_xref="taxon:10116"
                     /chromosome="7"
                     /map="7q36"
     gene            1..2337
                     /gene="Atf1"
                     /gene_synonym="Atf-1"
                     /note="activating transcription factor 1"
                     /db_xref="GeneID:315305"
                     /db_xref="RGD:1307360"
     exon            1..260
                     /gene="Atf1"
                     /gene_synonym="Atf-1"
                     /inference="alignment:Splign:2.1.0"
     exon            261..356
                     /gene="Atf1"
                     /gene_synonym="Atf-1"
                     /inference="alignment:Splign:2.1.0"
     CDS             267..1073
                     /gene="Atf1"
                     /gene_synonym="Atf-1"
                     /codon_start=1
                     /product="cyclic AMP-dependent transcription factor ATF-1"
                     /protein_id="NP_001094365.1"
                     /db_xref="GeneID:315305"
                     /db_xref="RGD:1307360"
                     /translation="MEDSHKSNTSETASQPGSTVPGIISQIVHQVSSLSESEESQDSS
                     DSIGSSQKAHGILARRPSYRKILKDLSSEDTRGRKGDGENPSISAVTSMSVPTPIYQT
                     SSGQYIAIAPNGALQLASPGPDGVQALQTLTMTNSSSAQQGAILQYAQTSDGQQILVP
                     SNQVVVQTASGDMQTYQIRTTPSATSLPQTMVMTSPVTLTSQTTKTDDPQLKREIRLM
                     KNREAARECRRKKKEYVKCLENRVAVLENQNKTLIEELKTLKDLYSHKSV"
     exon            357..457
                     /gene="Atf1"
                     /gene_synonym="Atf-1"
                     /inference="alignment:Splign:2.1.0"
     exon            458..588
                     /gene="Atf1"
                     /gene_synonym="Atf-1"
                     /inference="alignment:Splign:2.1.0"
     exon            589..768
                     /gene="Atf1"
                     /gene_synonym="Atf-1"
                     /inference="alignment:Splign:2.1.0"
     exon            769..928
                     /gene="Atf1"
                     /gene_synonym="Atf-1"
                     /inference="alignment:Splign:2.1.0"
     exon            929..2321
                     /gene="Atf1"
                     /gene_synonym="Atf-1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 tcccgcgcac tcctcggccc ccctccccag cccccggcct gtgcggatca tgccgccagc
       61 gacgcccctc gcggccggga aacggtagcc gggacggttg gctcttaagt tacgacgttc
      121 tttttccgcg ccccgccgac cgcagggacc ggcgccaccc cgccgcggtg cgcggctggc
      181 aagtgaggag tgaggtcggc gccgcctggg acgggggagt ggagcttccc gccccgggca
      241 gcggccagga ggcttcgcgg ttgattatgg aagattccca caagagtaac acttcagaga
      301 ctgcatcaca gcctggttca acagttccgg gaatcatttc tcagatagtc catcaggtgt
      361 catcgttgtc agaaagtgag gagtctcagg actcatctga cagcataggc tcctcacaga
      421 aagctcacgg gatcctggcg cggcgcccat cttacaggaa aattttgaaa gacctctctt
      481 ctgaagacac acggggcaga aaaggagacg gagaaaatcc cagcatttct gccgtcactt
      541 ctatgtctgt tccgactccc atctatcaga ctagcagcgg acagtacatt gccattgccc
      601 caaacggagc cttacagttg gccagtccag gcccagatgg agtacaggcc ctgcagacat
      661 tgaccatgac aaattcaagc agtgctcagc aaggggcgat cctccagtac gcgcagacct
      721 ctgacggaca gcagatactc gtcccgagca accaggtggt ggtgcagact gcatcaggag
      781 atatgcagac ctaccagatc cgtaccacac catctgccac gtcacttcca cagaccatgg
      841 tgatgacttc tcctgttacc cttacatctc agacaacaaa gacagatgac ccccaactca
      901 aaagagaaat acggctgatg aaaaacagag aagctgcccg ggagtgccgg cggaagaaga
      961 aggagtatgt gaagtgcctg gagaaccgag ttgctgttct ggaaaaccaa aataaaaccc
     1021 taatagagga gctaaagact ctgaaggacc tttattctca taaaagtgtt tgattcttta
     1081 aagagaaagt attttcgtgg acttttaagc ttaaaaatta ggtgtatttc tttttagtgg
     1141 aattgtatta attcaaaggt caaagaagcc actctgttgg gttgtcacag ccaatgagat
     1201 ggagggtgaa tggagacggc cttcaggaag ctgctggctc agctggaagc tcccaaagga
     1261 gagatgctca aggaaacgga ctttcagcag tttaaatgga aataaaataa tagtcagcaa
     1321 cgaaaatggc aggtgacatt agtgaagcag tcaatgcctg ctaagtcttt atctctgttc
     1381 cctaaaactt gcctttctgt gtgtgttgtg tgcgtgcgtg tgtgtgcgta tttctgccaa
     1441 taaatttaaa ttacaaatgt aaaagaatgc ataaaccgtt gctaagtgtg taaattatgt
     1501 gtctgactgt gtcgtactgt caggctgtgt tgagtgagtt tttcagttag ttttgttgga
     1561 ctagatggtt cgtgaagatc tgaacgatgt ggacatacat ccttctatgg tgatggtggc
     1621 ttgtgacttt ttatcagaat agaaagagaa ctgtctgcaa gtttgacagt ttaatagttt
     1681 ggttttttgc ttcctctgat aagggcgatt tttcttaaga acataataaa ttggtctttt
     1741 tttattttat ttttttgatt ctctaatcct gtatgcaggt gaagatcatt attcttttgt
     1801 gctttaacag aatgaagtgt ttacaaacgc ccttaaaatg tttaaataac ctgaagatgt
     1861 acaccaaagc tctcctgagg gattttataa tcatcttacc gtagtctgtc aggttctgag
     1921 agagttactg aggccatctc acatcgagac tgctgtgtgt agcctacggt acctttataa
     1981 aagaagtgac tgccgatata tttttatagt gaatctttat aaattctaat gttgagtttt
     2041 aaatgattat tttaaatgtt tatatagttt gtttagtaaa agaaaatttg tatctcaaag
     2101 tatcattttt atattatgag aagagtaaag ttttcaattg gctgataatt gaattgtatg
     2161 ttttatataa agttttatct gaagttccag ctgtggtcag tacagcagca tttaacctct
     2221 gtattctaat ctgtgttcac ttggaaactg caaaactatt gtgtgcctac acagtatgtt
     2281 tcatattgtc tatgaaatta aagaacattt gataagacta aaaaaaaaaa aaaaaaa
//
