LOCUS       NM_001035002            2330 bp    mRNA    linear   ROD 19-SEP-2024
DEFINITION  Rattus norvegicus ATPase family, AAA domain containing 1 (Atad1),
            mRNA; nuclear gene for mitochondrial product.
ACCESSION   NM_001035002 XM_220076
VERSION     NM_001035002.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2330)
  AUTHORS   Morgenstern,M., Peikert,C.D., Lubbert,P., Suppanz,I., Klemm,C.,
            Alka,O., Steiert,C., Naumenko,N., Schendzielorz,A., Melchionda,L.,
            Muhlhauser,W.W.D., Knapp,B., Busch,J.D., Stiller,S.B.,
            Dannenmaier,S., Lindau,C., Licheva,M., Eickhorst,C., Galbusera,R.,
            Zerbes,R.M., Ryan,M.T., Kraft,C., Kozjak-Pavlovic,V., Drepper,F.,
            Dennerlein,S., Oeljeklaus,S., Pfanner,N., Wiedemann,N. and
            Warscheid,B.
  TITLE     Quantitative high-confidence human mitochondrial proteome and its
            dynamics in cellular context
  JOURNAL   Cell Metab 33 (12), 2464-2483 (2021)
   PUBMED   34800366
REFERENCE   2  (bases 1 to 2330)
  AUTHORS   Bharti,P., Schliebs,W., Schievelbusch,T., Neuhaus,A., David,C.,
            Kock,K., Herrmann,C., Meyer,H.E., Wiese,S., Warscheid,B., Theiss,C.
            and Erdmann,R.
  TITLE     PEX14 is required for microtubule-based peroxisome motility in
            human cells
  JOURNAL   J Cell Sci 124 (Pt 10), 1759-1768 (2011)
   PUBMED   21525035
REFERENCE   3  (bases 1 to 2330)
  AUTHORS   Zhang,J., Wang,Y., Chi,Z., Keuss,M.J., Pai,Y.M., Kang,H.C.,
            Shin,J.H., Bugayenko,A., Wang,H., Xiong,Y., Pletnikov,M.V.,
            Mattson,M.P., Dawson,T.M. and Dawson,V.L.
  TITLE     The AAA+ ATPase Thorase regulates AMPA receptor-dependent synaptic
            plasticity and behavior
  JOURNAL   Cell 145 (2), 284-299 (2011)
   PUBMED   21496646
  REMARK    GeneRIF: This study identifies an AAA+ ATPase that plays a critical
            role in regulating the surface expression of AMPAR and thereby
            regulates synaptic plasticity and learning and memory.
REFERENCE   4  (bases 1 to 2330)
  AUTHORS   Dai,C., Liang,D., Li,H., Sasaki,M., Dawson,T.M. and Dawson,V.L.
  TITLE     Functional identification of neuroprotective molecules
  JOURNAL   PLoS One 5 (11), e15008 (2010)
   PUBMED   21124846
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 2330)
  AUTHORS   Ghosh,D., Lippert,D., Krokhin,O., Cortens,J.P. and Wilkins,J.A.
  TITLE     Defining the membrane proteome of NK cells
  JOURNAL   J Mass Spectrom 45 (1), 1-25 (2010)
   PUBMED   19946888
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC094514.1.
            
            On Oct 26, 2005 this sequence version replaced XM_220076.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC094514.1, SRR8487231.65694.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760389
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..2330
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q52"
     gene            1..2330
                     /gene="Atad1"
                     /gene_synonym="Ab2-088"
                     /note="ATPase family, AAA domain containing 1"
                     /db_xref="GeneID:309532"
                     /db_xref="RGD:1308570"
     exon            1..28
                     /gene="Atad1"
                     /gene_synonym="Ab2-088"
                     /inference="alignment:Splign:2.1.0"
     exon            29..203
                     /gene="Atad1"
                     /gene_synonym="Ab2-088"
                     /inference="alignment:Splign:2.1.0"
     CDS             42..1127
                     /gene="Atad1"
                     /gene_synonym="Ab2-088"
                     /EC_number="3.6.1.3"
                     /note="ATPase family AAA domain-containing protein 1;
                     neuroprotective protein 6; thorase"
                     /codon_start=1
                     /product="outer mitochondrial transmembrane helix
                     translocase"
                     /protein_id="NP_001030174.1"
                     /db_xref="GeneID:309532"
                     /db_xref="RGD:1308570"
                     /translation="MVHAEAFSRPLSRNEVVGLIFRLTIFGAVTYFTIKWMVDAIDPT
                     RKQKVEAQKQAEKLMKQIGVKNVKLSEYEMSIAAHLVDPLNMHVTWSDIAGLDDVITD
                     LKDTVILPIKKKHLFENSRLLQPPKGVLLYGPPGCGKTLIAKATAKEAGCRFINLQPS
                     TLTDKWYGESQKLAAAVFSLAIKLQPSIIFIDEIDSFLRNRSSSDHEATAMMKAQFMS
                     LWDGLDTDHSCQVIVMGATNRPQDLDSAIMRRMPTRFHINQPALKQREAILKLILKNE
                     NVDRHVDLLEVAQETDGFSGSDLKEMCRDAALLCVREYVNSTSEESHDEDEIRPVQQQ
                     DLHRAIEKMKKSKDAAFQSVLTHVCLD"
     exon            204..302
                     /gene="Atad1"
                     /gene_synonym="Ab2-088"
                     /inference="alignment:Splign:2.1.0"
     exon            303..423
                     /gene="Atad1"
                     /gene_synonym="Ab2-088"
                     /inference="alignment:Splign:2.1.0"
     exon            424..624
                     /gene="Atad1"
                     /gene_synonym="Ab2-088"
                     /inference="alignment:Splign:2.1.0"
     exon            625..731
                     /gene="Atad1"
                     /gene_synonym="Ab2-088"
                     /inference="alignment:Splign:2.1.0"
     exon            732..821
                     /gene="Atad1"
                     /gene_synonym="Ab2-088"
                     /inference="alignment:Splign:2.1.0"
     exon            822..872
                     /gene="Atad1"
                     /gene_synonym="Ab2-088"
                     /inference="alignment:Splign:2.1.0"
     exon            873..1006
                     /gene="Atad1"
                     /gene_synonym="Ab2-088"
                     /inference="alignment:Splign:2.1.0"
     exon            1007..2305
                     /gene="Atad1"
                     /gene_synonym="Ab2-088"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cttctgtcgt ctctggtctt acctctgggt taacaatcaa gatggtacat gctgaagcct
       61 tttctcgtcc attgagtcgg aacgaagttg tcggtttaat ttttcgttta acaatctttg
      121 gtgcagtaac atacttcact attaaatgga tggtagatgc cattgacccc accaggaagc
      181 agaaagtgga agctcagaaa caggcggaaa aactgatgaa gcaaattggt gtgaaaaatg
      241 tgaagctttc agagtatgag atgagtattg ctgctcatct ggtagaccct cttaatatgc
      301 atgttacttg gagtgatata gcaggtttag atgatgttat tacagatctg aaagacacag
      361 tcatcctacc tatcaaaaag aagcatttgt ttgagaattc cagacttctg cagcctccca
      421 aaggtgttct cctgtatgga cctccgggct gtgggaaaac attaattgcc aaagcgacag
      481 ccaaagaagc gggctgtcga tttattaacc ttcagccttc cacactgaca gataagtggt
      541 atggagaatc tcagaaactg gctgctgctg tcttctccct ggccataaag ctacagccgt
      601 ctatcatatt tatcgatgaa atagactcat ttctacgaaa tcgttccagt tccgaccacg
      661 aagctacagc aatgatgaaa gcccagttta tgagtctttg ggatggactg gacactgatc
      721 acagctgcca ggtcatagtg atgggagcta ccaatcgtcc tcaagacctt gactctgcta
      781 taatgagaag aatgcccaca agatttcata ttaaccagcc tgctctaaaa caaagagaag
      841 caattttaaa actcatcttg aaaaatgaaa atgtggatag acatgtagat cttctagaag
      901 ttgcccagga aactgatggg ttttcaggaa gtgacctaaa agaaatgtgt cgagatgctg
      961 ccctcctctg cgtcagggaa tatgtcaatt ctacatcaga agaaagtcat gacgaagatg
     1021 aaatccggcc tgtgcagcag caggacttgc atcgggcaat tgagaagatg aagaaatcaa
     1081 aggatgcagc gtttcagagc gttctgactc acgtttgttt agattaggag taaagatcgt
     1141 ttgtgtgctt cagtgatctc gtgggacggg ctctcatctg tacagcaggg agggagatcc
     1201 agacttgtgg ttttctactc agatctctgg tctgttatat aaatggtgtt cctgcttgtc
     1261 agaaatcatg aggaggaagc tgagtgcgac ctgagtgtgg gtgcttgttt gaccttttta
     1321 gccatatgct gttatagcct tatagagtct aagctggtct tatgtagtta ctgatttgtt
     1381 gtcattagta aggaatgggg tgtggttagg tgctggtttc tagacatgtg agtgtgtgtg
     1441 agtgtgtgtg agtgtgtgtg tgtgtgtgtg agtgtttatc aaatgtatat atacactttt
     1501 ttttatattc tgtagatagg tttgactttt tttttttaaa ccccaactac tgaacccaaa
     1561 agtaccagat agtttgtagc aaaactggga tgtaaggcag agttgacagg cacagcgaga
     1621 ctcagccatt cctagtcgtc acttgtttgg gccgtttttg agttgaacat ttcctgtgca
     1681 gttggtggaa tcaaccacac ctgaacatgt gtgtgtcagt ggtaatggct gtcgggagag
     1741 tcagataaca aacgcgattt gctctgcgat cggcgactcc acctcactct gctgtgacac
     1801 cgagcagaca ttttgaagtt ttacactgaa ttatattaag gattgaaaac ctttcaaaag
     1861 aatgggtttg agaaacttca gtactctttt agtacgtgta cataactctc agtgtaacag
     1921 ttctgtaact gtattcctta aatgttgttt gaaagttaag tgttctttaa ttatgttcaa
     1981 atttaatttg gttatccaaa caaaatgata gtttatataa atagttgtta ctaaatgtgc
     2041 taaaaaatac tcactttgta acttaaattt aaaaattttc tcaatagtat aaaatgggta
     2101 caaataattc atatcaaaat tcttgtattg tatctgtagt cactcgatgc tatgtgaacc
     2161 acatacaaaa ctcttctttt tttcaaacct ccactagcca gaattctgtt ccaggcatgt
     2221 gacatgtgac aaagcaagat gataatgccg cagcacagtc ttgaggtgcc tccgactcac
     2281 cagaacgatt aaactatgac aagaaaaaaa aaaaaaaaaa aaaaaaaaaa
//
