LOCUS       XM_039106659            6561 bp    mRNA    linear   ROD 11-JUN-2023
DEFINITION  PREDICTED: Rattus norvegicus ASXL transcriptional regulator 1
            (Asxl1), transcript variant X1, mRNA.
ACCESSION   XM_039106659
VERSION     XM_039106659.1
DBLINK      BioProject: PRJNA677964
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_051338.1) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            [WARNING] On Feb 1, 2024 this sequence was replaced by
            NM_001427647.1.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_015227675.2-RS_2023_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.1
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/06/2023
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6561
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN/NHsdMcwi"
                     /db_xref="taxon:10116"
                     /chromosome="3"
                     /sex="male"
                     /tissue_type="kidney"
                     /geo_loc_name="USA: Wisconsin, Milwaukee, Medical College
                     of Wisconsin"
                     /collection_date="2019-03-08"
                     /collected_by="Rebecca Schilling"
     gene            1..6561
                     /gene="Asxl1"
                     /note="ASXL transcriptional regulator 1; Derived by
                     automated computational analysis using gene prediction
                     method: Gnomon. Supporting evidence includes similarity
                     to: 47 ESTs, 3 long SRA reads, 6 Proteins, and 100%
                     coverage of the annotated genomic feature by RNAseq
                     alignments, including 216 samples with support for all
                     annotated introns"
                     /db_xref="GeneID:311553"
                     /db_xref="RGD:1561878"
     CDS             74..4657
                     /gene="Asxl1"
                     /codon_start=1
                     /product="polycomb group protein ASXL1 isoform X1"
                     /protein_id="XP_038962587.1"
                     /db_xref="GeneID:311553"
                     /db_xref="RGD:1561878"
                     /translation="MKDKQKKKKERTWAEAARLVLENYSDAPMTPKQILQVIEAEGLK
                     EMRSGTSPLACLNAMLHSNSRGGEGLFYKLPGRISLFTLKKDAVQWSRNVATLDGEEP
                     EDSADVESCGSNEASTVSGENDVSLDETSSNASCATEPQGRSLSNPRDGHRASSQANK
                     QKKRTGVMLPRVVLTPLKVNGAHVEPASGFSGRHADGESGSPSSSSSGSLALGNSTIR
                     SQAEVTRDPAPLLRGFRKPATGQMKRNRGEEVDFETPGSILVNTNLRALINSRTFHAL
                     PSHFQQQLLFLLPEVDRQVGTDGLLRLSSSALNNEFFTHAAQSWRERLAEGEFTHEMQ
                     VRLRQEMEKEKKVEQWKEKFFEDYYGQKLGLTKEESLQQKEDQEEAKIKSGFCVSGES
                     VRPQRGPNTRQRDGHFKKRSRPDLRTRSRRNLYKKQEPEQAGIAKDANAAPDVSLSKD
                     AKTDSPGVNSPPGPDVSSPASGQEGPKCPSEPVASQIQTEMDNLACASTSPDRTPTLP
                     QDSVDQETKDQKRKSFEQEASASFPEKKPRLEDRQSFRNTIESVHTEKPQPTKEEPKV
                     PPIRIQLSRIKPPWVAKGRPTYQICPRIVPITESSCRGWTGARTLADIKARALQARGA
                     RGYHCNREAAATAIGGGGGPGGGGSGAIDEGGGRDGSSGDGSEACGHSEPRGASSNPG
                     ESASDLQRTQLLPSCPLNGEHTQADAAMVRAKGEDSASLRKEENGLLTRAPGVLTSGL
                     EDASQPPVAPTGDQPCQALPPLSSQTPVAEMLAEQAKLLPDDRTECEPRTPSWEKGGE
                     DQGPTVPSEGSSGQSPLGDILGGGNDQIFDNMKEPVNMTPAFISELSLANSLQDRPSD
                     DELGVGATGPHIRESRQETLKTEAFVSGSPGSWVPILSNYEVIKESYPEARENAPCLE
                     PQDGKGWERTVPLVAAMPGGHAEVLPYHESCASHWTAPPPGVLGSTCSDSQQVDLERL
                     EMNGISDILSPHNESTDTASDSEGHFSEDSSEVDACEITVVKGLLGGSEKQDWDPSAS
                     LSKASTDLSVLTRTEGVATPQSWVSRVCAVPHKIPDSLLLSSTECQPRSVCPPKPGSS
                     AEVTNPLVMHLLHGNLPLEKVLAPGHRSNQPESPHLPLREQNQDRGTLQGTGGDNHLV
                     ARSNPGSVQTLKESILAQSYGASAGLVRAKASKAPGMSQKIARLVPSSDSQHPVTELT
                     PSSSNLEEIDSKEHLSSFLCEEQKEAHSLSQGSDPGAAPGQFLGDHTTSKVPCFSSTN
                     VSLSFGSEQTDGTLSDQNDVGGREKKLFGPRNTVATLQYPRSEEQIPLPAEVPPVFPS
                     RKIEPSKNSVPDGVQTARENRTPKPPAVSAGSIKTEQTFLRDPIKADAENRKAAGYSS
                     LELVGHLQGMPFVVDLPFWKLPREPGKGFSQPLEPPSIPSQLSIKQALYGKFSKLQLS
                     PSSFNYSSSSAAFPRGLAGGVVQLSHKASFGTGHTASLSLQMFTDSSAVESISLQCAC
                     SLKAMIMCQGCGAFCHDDCIGPSKLCVLCLVVR"
ORIGIN      
        1 ccgcgccgcc accgccccag cccgccccgc ccgaaggacc cgcgtggagc cgccaccgcc
       61 gccgcggagg aggatgaagg acaaacagaa gaagaagaag gagcgcacgt gggccgaggc
      121 cgcgcgcctg gtgttagaaa actactcgga tgctccaatg acaccaaaac aaattctgca
      181 ggtcatagag gcagaaggac taaaggaaat gagaagtggg acatcccccc tcgcgtgcct
      241 caatgccatg ctacattcca actcaagagg aggagaaggg ctattttata aattacctgg
      301 ccggattagt cttttcacac tcaagaaaga tgctgtgcag tggtctagaa atgtagctac
      361 actggatgga gaagaaccag aggactccgc tgatgtggaa agctgtgggt ctaatgaagc
      421 cagcactgtg agtggtgaaa atgatgtgtc tctggatgaa acatcctcaa atgcatcctg
      481 cgctacagag cctcagggca ggtccctctc caatcccagg gacggccaca gggcttcctc
      541 acaggcaaac aaacaaaaga aaaggactgg ggttatgctg cctcgtgttg ttctgactcc
      601 tctgaaggta aacggggccc acgttgaacc tgcatcgggg ttctcaggcc gtcatgcaga
      661 tggtgagagt ggcagtccat ccagcagcag cagcggctct ctggctttgg gcaacagtac
      721 tattcgaagc caggctgagg tcactcggga ccctgcccct ctcctgagag gcttccggaa
      781 gccagccaca ggtcaaatga agcgcaacag aggggaagag gtagattttg agacgcctgg
      841 gtccattctt gttaacacca atctccgtgc tttgataaac tctcggacct tccatgccct
      901 gccatcacac ttccagcagc aactcctctt cctcctgcct gaagtggata gacaggtggg
      961 gacggatggc ctgttgcgcc tcagcagcag tgcactcaat aatgagtttt tcacccacgc
     1021 agctcagagc tggagggaac gcctggctga aggtgaattc actcatgaga tgcaagtcag
     1081 gctaagacaa gaaatggaaa aggagaagaa ggtggaacaa tggaaggaga agttctttga
     1141 agattactat ggacagaaat tgggtttgac caaagaagaa tcactgcagc agaaagaaga
     1201 ccaggaggag gccaaaatca agagtggctt ttgtgtctca ggggagtcag tgcggccaca
     1261 gcgtgggccc aacacccgtc aacgggacgg gcattttaag aaacgttctc ggccagatct
     1321 ccgaaccaga tctagaagga atctgtacaa aaaacaggag ccagaacaag cagggattgc
     1381 taaagatgca aatgctgcac cagatgtttc actctctaaa gatgctaaga ccgactcacc
     1441 aggggtgaac agtccccctg ggccagatgt gtcctcccca gcatctggac aggagggtcc
     1501 caagtgtcca agtgaacctg tggcttccca gatacaaaca gaaatggaca acttggcctg
     1561 tgcctctaca tctccagaca gaacccctac cttacctcag gacagtgtgg atcaagagac
     1621 aaaggatcag aagaggaaat cctttgagca ggaagcctct gcatcctttc ccgaaaagaa
     1681 gccccggctt gaagatcgtc agtcctttcg taacacaatt gaaagtgttc acaccgaaaa
     1741 gccacagccc actaaagagg agcccaaagt cccgcccatc cggattcaac tttcacgtat
     1801 caaaccaccc tgggtggcta aaggtcggcc cacttaccag atatgccccc ggatcgtccc
     1861 catcacggag tcttcctgcc ggggttggac tggtgccagg accctcgcag acattaaagc
     1921 ccgtgctttg caggcccgag gggcgagagg ctaccactgc aatcgagagg cggctgccac
     1981 tgccatcgga ggggggggtg gcccgggtgg aggtggcagt ggggccatcg atgagggagg
     2041 tggcagagac ggcagcagtg gtgatggtag tgaggcctgt ggccactctg agcccagggg
     2101 agcctcaagc aaccctggag agagtgcgtc agatctacag cgaacacaac tactgccgtc
     2161 ttgtcctctg aatggagagc acactcaggc tgatgccgcc atggtcagag ccaaaggaga
     2221 ggactctgct tctctcagaa aggaagagaa cggcctgttg acgagggccc cgggtgtgct
     2281 tacaagtgga ctggaagatg cctcccaacc ccctgttgct cccactggag accagccctg
     2341 tcaggctttg ccccctttgt cctcccaaac tccagtggct gagatgttag cagagcaggc
     2401 taagttgctt ccagatgata ggactgagtg tgagcctcgt actccttcct gggagaaggg
     2461 tggtgaagac caaggaccca ccgttccctc agagggtagt tctggacagt ctccattggg
     2521 agatatacta ggaggaggaa atgaccagat ctttgataat atgaaggagc ctgtaaatat
     2581 gacacctgct tttatatctg aattgtcatt ggctaactcc ctacaggata gaccttctga
     2641 tgatgaatta ggagttggtg ccacaggccc ccacataagg gagagtagac aagaaacttt
     2701 gaaaactgag gcttttgtat ctggtagtcc tggctcctgg gtacccattc tgtcaaatta
     2761 tgaggtaata aaagaatctt atccagaagc cagagaaaat gcaccatgtc tggaacccca
     2821 ggatggaaaa gggtgggaga gaactgttcc ccttgtggct gccatgcctg gggggcatgc
     2881 agaagttttg ccctaccatg agagctgtgc ttcacactgg actgcacctc ctccaggagt
     2941 cctgggcagc acttgcagtg acagtcagca ggtagacctt gaaagactgg aaatgaacgg
     3001 catctctgac atactgagtc ctcacaacga atccacagat acagcctctg actctgaagg
     3061 ccacttttct gaggacagca gtgaggttga tgcatgtgaa atcacagtgg taaaagggtt
     3121 gttgggtggg agtgaaaaac aggactggga tccatctgcc tcactgtcca aggcaagcac
     3181 tgacctaagt gtgcttacaa ggacagaagg ggtggctact cctcagagct gggtatctag
     3241 agtatgtgca gtcccccaca agatcccaga ctccctgctg ctgtccagta ctgagtgcca
     3301 gccccggtct gtgtgcccac caaagcctgg ttcttcagcg gaggttacaa acccacttgt
     3361 gatgcacctg ctgcatggta atttgcccct ggagaaggtt cttgctccag gtcatagaag
     3421 caaccaacct gaatccccac atctgccact tagagaacag aaccaggata gaggcactct
     3481 gcaaggtaca gggggagaca atcacctagt tgccagaagc aaccctggtt ctgtacaaac
     3541 attgaaagag tctattctgg cccaaagcta tggagcaagt gctggtcttg tcagggcaaa
     3601 ggcctccaaa gctcctggaa tgtcccagaa gattgccagg ttggttccaa gttcagactc
     3661 ccagcatcca gtgacagaac tgacaccttc ctctagcaac ctggaagaaa tcgattccaa
     3721 agagcatctc tcttccttcc tttgtgaaga gcagaaagaa gcccattccc tgtctcaagg
     3781 cagtgatccg ggtgctgccc caggccagtt tctaggagat cacactacct ccaaagtgcc
     3841 atgtttctcc tccacaaatg tgagcctctc ctttggttct gagcagacag atgggaccct
     3901 gagtgatcag aacgatgttg gtggtcgcga gaagaaactg tttggtccta ggaatacagt
     3961 tgccaccctt cagtacccta ggtctgaaga gcagatacca ctacctgctg aggtccctcc
     4021 agtgtttccc agtaggaaga tagaaccaag caaaaactct gtgcctgatg gtgtgcagac
     4081 tgcaagggaa aacaggacgc ccaaaccacc agctgtctct gctggcagca tcaagacaga
     4141 gcagacattt ttgagggatc ccattaaagc agatgcagag aacagaaaag ctgcagggta
     4201 cagttctctg gaactagtgg gtcacttgca aggaatgcct tttgttgtgg acctgccttt
     4261 ctggaaatta cccagagagc cagggaaagg gttcagtcag cccctggagc cgccttccat
     4321 cccctcccaa ctcagcatca agcaggcttt gtacgggaag ttttccaaac tgcagctgag
     4381 tcccagcagc tttaattact cctccagctc ggccgccttt cccagaggcc tcgctggtgg
     4441 tgtggtgcag ctgagccaca aagccagctt tggtacaggc cacactgcat cactgtccct
     4501 acagatgttc actgacagca gtgcagtaga aagcatctct ctccagtgtg catgcagcct
     4561 gaaagccatg atcatgtgcc aaggctgcgg agcgttctgc cacgacgact gcattggacc
     4621 ttcaaagctc tgtgtattgt gccttgtggt gagataataa attatggcca ttggaaacat
     4681 tgtacattta gtgtgtgtat tttaataatg gttgatctta aatctgtata cagaatatca
     4741 ctgatataat gaactctcac tctagatgag ataaatcttg cctccccatg aaatttatag
     4801 tgctgaagcc ctctgtcact tggcaccctt ctagccttgc cagaagggtt ttccaggaga
     4861 agggggcact atggttgcct aagaccatcc agcctaaacc ctcttgtagt caggcagtac
     4921 agtgtggcag ggcaacctgt ctgacaccca aatggacttg aaattgaagc aggaaggttg
     4981 ggttctccat ggatggaact cccctgcctg cactgagcag gaatgtccgt cttccactgc
     5041 cctccctgcc atctgctgct tagcttgggg agttgatggt tgcagaagcc acacagggtt
     5101 aaagtaactt ccgtctttat ccaccagggg atcaaacacc caatgactta gatgtcatat
     5161 ttctgtcatt tgccagttga tggagccaag ttgacctttg gttctggtgc ttcacccagt
     5221 ttggaacttt aatctgtaac ccagggatcc acggattctc ttggaagctt gaatagccct
     5281 tcttggacaa tggggtctgg aaatagggct gtctgctgtg gaaatgccat ctgtagactt
     5341 cagagtcaac tgtacagatg tttgcagggg actcctgctt gccacccacc cgtcacattt
     5401 gattccgtgg gagtgggcac ccatgcactt gtgtatgtga aagtcatttt acatttccaa
     5461 gcagtctgtt tcttattttt atattttaac tctattcttg gatgtataaa gtgaaccttt
     5521 tcgcttctgt aagtatgctc tatgcacctc taacgtttta tcctgtattt atatgttgta
     5581 cacagtattg gccaattctg taaatggatg tattgtacag agaacatgaa cgtctcttcc
     5641 ttagtttacg tcttcagcac ccttgattaa aatggtgttg tctacttccg tgcaccaact
     5701 gtcaaaacca ctgagtgctg tgttgcctga tgtgagaagg aagttactga cttgtgacct
     5761 atggttggcc ctgtgccttg tcacctgtgt caccagggaa tctcctgcag tctgcgcgcc
     5821 acagacacca ttgatcgaac atgtcttgtt ccttgtatct attctcttcc agccttgagt
     5881 ggctgcgctg ccgccacata tgacaaattg tcatcaccag tgttaagtcc tggattcatg
     5941 ggtgagttcc ttggacaacc ccgagacagg cttctggatc tggctccagg gtcatcacct
     6001 gtcaaagcaa tattggggat cgctaggctc cttttgactt acttttgaca gtaggtttca
     6061 ggggaacaaa gccatgcctg ctgcctgcct ctctcctaac atggttccat caagtagatg
     6121 ccctttgtat ttgtctgacc tcattctggt tcctaccatt tctgtatttt tacttgaaag
     6181 ttgggagtcc ttgtttaatt taggtctgtc gtcttgtgtg agtgtttctg tatgaagtat
     6241 aaaaatttgt gtgccttgag caagtctcat tttctttgta agctgcctct ctgccatttc
     6301 atgaggtggc tctctttttg gtggggaggg ggctggggga tccatgaagt atgagtgagg
     6361 aactggtagt gaattcagta ttggccaagt ccatgttgtg tgctcagaag tctctttacc
     6421 aaagaccagg agcaggagct aagcatgtcc agtcctcctc ttgtgcgacc tttgacagtg
     6481 gtctggtcca cggggctgct cagaaaagcg ctgctcttgt atgtctcact ggtattggaa
     6541 aataaacctg tacaacctgc a
//
