LOCUS       NM_001401939            6612 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus aspartate-beta-hydroxylase (Asph), transcript
            variant 1, mRNA.
ACCESSION   NM_001401939 XM_006237858
VERSION     NM_001401939.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 6612)
  AUTHORS   Srikanth,S., Jew,M., Kim,K.D., Yee,M.K., Abramson,J. and Gwack,Y.
  TITLE     Junctate is a Ca2+-sensing structural component of Orai1 and
            stromal interaction molecule 1 (STIM1)
  JOURNAL   Proc Natl Acad Sci U S A 109 (22), 8682-8687 (2012)
   PUBMED   22586105
REFERENCE   2  (bases 1 to 6612)
  AUTHORS   Lee,K.W., Maeng,J.S., Choi,J.Y., Lee,Y.R., Hwang,C.Y., Park,S.S.,
            Park,H.K., Chung,B.H., Lee,S.G., Kim,Y.S., Jeon,H., Eom,S.H.,
            Kang,C., Kim,D.H. and Kwon,K.S.
  TITLE     Role of Junctin protein interactions in cellular dynamics of
            calsequestrin polymer upon calcium perturbation
  JOURNAL   J Biol Chem 287 (3), 1679-1687 (2012)
   PUBMED   22123818
REFERENCE   3  (bases 1 to 6612)
  AUTHORS   Noda,T., Shimoda,M., Ortiz,V., Sirica,A.E. and Wands,J.R.
  TITLE     Immunization with aspartate-beta-hydroxylase-loaded dendritic cells
            produces antitumor effects in a rat model of intrahepatic
            cholangiocarcinoma
  JOURNAL   Hepatology 55 (1), 86-97 (2012)
   PUBMED   21898484
REFERENCE   4  (bases 1 to 6612)
  AUTHORS   Treves,S., Vukcevic,M., Griesser,J., Armstrong,C.F., Zhu,M.X. and
            Zorzato,F.
  TITLE     Agonist-activated Ca2+ influx occurs at stable plasma membrane and
            endoplasmic reticulum junctions
  JOURNAL   J Cell Sci 123 (Pt 23), 4170-4181 (2010)
   PUBMED   21062895
REFERENCE   5  (bases 1 to 6612)
  AUTHORS   Ketteler,R., Sun,Z., Kovacs,K.F., He,W.W. and Seed,B.
  TITLE     A pathway sensor for genome-wide screens of intracellular
            proteolytic cleavage
  JOURNAL   Genome Biol 9 (4), R64 (2008)
   PUBMED   18387192
  REMARK    Publication Status: Online-Only
REFERENCE   6  (bases 1 to 6612)
  AUTHORS   Feldmann,G., Nattermann,J., Nischalke,H.D., Gorschluter,M.,
            Kuntzen,T., Ahlenstiel,G., Gerhardt,T., Wolff,M., Sauerbruch,T.,
            Spengler,U. and Dumoulin,F.L.
  TITLE     Detection of human aspartyl (asparaginyl) beta-hydroxylase and
            homeobox B7 mRNA in brush cytology specimens from patients with
            bile duct cancer
  JOURNAL   Endoscopy 38 (6), 604-609 (2006)
   PUBMED   16673309
REFERENCE   7  (bases 1 to 6612)
  AUTHORS   Feriotto,G., Finotti,A., Volpe,P., Treves,S., Ferrari,S.,
            Angelelli,C., Zorzato,F. and Gambari,R.
  TITLE     Myocyte enhancer factor 2 activates promoter sequences of the human
            AbetaH-J-J locus, encoding aspartyl-beta-hydroxylase, junctin, and
            junctate
  JOURNAL   Mol Cell Biol 25 (8), 3261-3275 (2005)
   PUBMED   15798210
REFERENCE   8  (bases 1 to 6612)
  AUTHORS   Treves,S., Franzini-Armstrong,C., Moccagatta,L., Arnoult,C.,
            Grasso,C., Schrum,A., Ducreux,S., Zhu,M.X., Mikoshiba,K.,
            Girard,T., Smida-Rezgui,S., Ronjat,M. and Zorzato,F.
  TITLE     Junctate is a key element in calcium entry induced by activation of
            InsP3 receptors and/or calcium store depletion
  JOURNAL   J Cell Biol 166 (4), 537-548 (2004)
   PUBMED   15302852
REFERENCE   9  (bases 1 to 6612)
  AUTHORS   Dinchuk,J.E., Focht,R.J., Kelley,J.A., Henderson,N.L.,
            Zolotarjova,N.I., Wynn,R., Neff,N.T., Link,J., Huber,R.M.,
            Burn,T.C., Rupar,M.J., Cunningham,M.R., Selling,B.H., Ma,J.,
            Stern,A.A., Hollis,G.F., Stein,R.B. and Friedman,P.A.
  TITLE     Absence of post-translational aspartyl beta-hydroxylation of
            epidermal growth factor domains in mice leads to developmental
            defects and an increased incidence of intestinal neoplasia
  JOURNAL   J Biol Chem 277 (15), 12970-12977 (2002)
   PUBMED   11773073
REFERENCE   10 (bases 1 to 6612)
  AUTHORS   Jones,L.R., Zhang,L., Sanborn,K., Jorgensen,A.O. and Kelley,J.
  TITLE     Purification, primary structure, and immunological characterization
            of the 26-kDa calsequestrin binding protein (junctin) from cardiac
            junctional sarcoplasmic reticulum
  JOURNAL   J Biol Chem 270 (51), 30787-30796 (1995)
   PUBMED   8530521
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000005.1.
            
            On Mar 3, 2022 this sequence version replaced XM_006237858.4.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on transcript alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26360190.2887215.1,
                                           SRR26643429.18824.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA5760393,
                                           SAMEA5760433 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-301               JAXUCZ010000005.1  27610915-27611215   c
            302-451             JAXUCZ010000005.1  27576865-27577014   c
            452-520             JAXUCZ010000005.1  27573633-27573701   c
            521-613             JAXUCZ010000005.1  27549994-27550086   c
            614-688             JAXUCZ010000005.1  27547368-27547442   c
            689-802             JAXUCZ010000005.1  27543325-27543438   c
            803-835             JAXUCZ010000005.1  27541563-27541595   c
            836-892             JAXUCZ010000005.1  27540855-27540911   c
            893-937             JAXUCZ010000005.1  27539295-27539339   c
            938-970             JAXUCZ010000005.1  27538838-27538870   c
            971-1009            JAXUCZ010000005.1  27535477-27535515   c
            1010-1045           JAXUCZ010000005.1  27534811-27534846   c
            1046-1090           JAXUCZ010000005.1  27529470-27529514   c
            1091-1176           JAXUCZ010000005.1  27474151-27474236   c
            1177-1263           JAXUCZ010000005.1  27469663-27469749   c
            1264-1414           JAXUCZ010000005.1  27463687-27463837   c
            1415-1551           JAXUCZ010000005.1  27461363-27461499   c
            1552-1650           JAXUCZ010000005.1  27452107-27452205   c
            1651-1740           JAXUCZ010000005.1  27450392-27450481   c
            1741-1878           JAXUCZ010000005.1  27445064-27445201   c
            1879-2014           JAXUCZ010000005.1  27427339-27427474   c
            2015-2106           JAXUCZ010000005.1  27420366-27420457   c
            2107-2240           JAXUCZ010000005.1  27419895-27420028   c
            2241-6612           JAXUCZ010000005.1  27398949-27403320   c
FEATURES             Location/Qualifiers
     source          1..6612
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="5"
                     /map="5q13"
     gene            1..6612
                     /gene="Asph"
                     /note="aspartate-beta-hydroxylase"
                     /db_xref="GeneID:312981"
                     /db_xref="RGD:1312000"
     exon            1..301
                     /gene="Asph"
                     /inference="alignment:Splign:2.1.0"
     CDS             178..2391
                     /gene="Asph"
                     /EC_number="1.14.11.16"
                     /note="isoform 1 is encoded by transcript variant 1;
                     aspartyl/asparaginyl beta-hydroxylase; junctin; junctate"
                     /codon_start=1
                     /product="aspartyl/asparaginyl beta-hydroxylase isoform 1"
                     /protein_id="NP_001388868.1"
                     /db_xref="GeneID:312981"
                     /db_xref="RGD:1312000"
                     /translation="MAPRKNAKGGGGNSSSSGSGSGSGSPSTGSSGSSSSPGARREAK
                     HGGHKNGRRGGISGGSFFTWFMVIALLGVWTSVAVVWFDLVDYEEVLGKLGVYDADGD
                     GDFDVDDAKVLLGLKERSTSERTFPPEEAETQAELEEQAPEGAEAQNVEDEVKEQIQS
                     LLQESVHTDHDLEADGPAGEPQSEVEDFLTATDSDDRFEALEPGTVHEDTEDSYHVEE
                     TASQNHPNDAEEVMSEQESSDHGEAVTDDGLQQHAEEVRHEDYDEPVYEPSENERIEI
                     SDNAIDDSNIISEEINVASVEEQQDTPPVKKKKPKLLNKFDKTIKAELDAAEKLRKRG
                     KIEEAVSAFEELVRRYPQSPRARYGKAQCEDDLAEKQRSNEVLRRAIETYQEAASLPD
                     APTDLVKLSLKRRSERQQFLGHMRGSLLTLQRLVQLFPSDTTLKNDLGVGYLLMGDND
                     SAKKVYEEVLNVTPNDGFAKVHYGFILKAQNRIAESIPYLKEGIESGDPGTDDGRFYF
                     HLGDAMQRVGNKEAYKWYELGHKRGHFASVWQRSLYNVNGLKAQPWWTPRETGYTELV
                     KSLERNWKLIRDEGLMVMDKAKGLFLPEDENLREKGDWSQFTLWQQGRKNENACKGAP
                     KTCTLLEKFSETTGCRRGQIKYSIMHPGTHVWPHTGPTNCRLRMHLGLVIPKEGCKIR
                     CANETRSWEEGKVLIFDDSFEHEVWQDASSFRLIFIVDVWHPELTPQQRRSLPAI"
     exon            302..451
                     /gene="Asph"
                     /inference="alignment:Splign:2.1.0"
     exon            452..520
                     /gene="Asph"
                     /inference="alignment:Splign:2.1.0"
     exon            521..613
                     /gene="Asph"
                     /inference="alignment:Splign:2.1.0"
     exon            614..688
                     /gene="Asph"
                     /inference="alignment:Splign:2.1.0"
     exon            689..802
                     /gene="Asph"
                     /inference="alignment:Splign:2.1.0"
     exon            803..835
                     /gene="Asph"
                     /inference="alignment:Splign:2.1.0"
     exon            836..892
                     /gene="Asph"
                     /inference="alignment:Splign:2.1.0"
     exon            893..937
                     /gene="Asph"
                     /inference="alignment:Splign:2.1.0"
     exon            938..970
                     /gene="Asph"
                     /inference="alignment:Splign:2.1.0"
     exon            971..1009
                     /gene="Asph"
                     /inference="alignment:Splign:2.1.0"
     exon            1010..1045
                     /gene="Asph"
                     /inference="alignment:Splign:2.1.0"
     exon            1046..1090
                     /gene="Asph"
                     /inference="alignment:Splign:2.1.0"
     exon            1091..1176
                     /gene="Asph"
                     /inference="alignment:Splign:2.1.0"
     exon            1177..1263
                     /gene="Asph"
                     /inference="alignment:Splign:2.1.0"
     exon            1264..1414
                     /gene="Asph"
                     /inference="alignment:Splign:2.1.0"
     exon            1415..1551
                     /gene="Asph"
                     /inference="alignment:Splign:2.1.0"
     exon            1552..1650
                     /gene="Asph"
                     /inference="alignment:Splign:2.1.0"
     exon            1651..1740
                     /gene="Asph"
                     /inference="alignment:Splign:2.1.0"
     exon            1741..1878
                     /gene="Asph"
                     /inference="alignment:Splign:2.1.0"
     exon            1879..2014
                     /gene="Asph"
                     /inference="alignment:Splign:2.1.0"
     exon            2015..2106
                     /gene="Asph"
                     /inference="alignment:Splign:2.1.0"
     exon            2107..2240
                     /gene="Asph"
                     /inference="alignment:Splign:2.1.0"
     exon            2241..6612
                     /gene="Asph"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ggagtcgcag gctaggcgca cgcgaggctg gccgcgccgc tgcacgcttg tgctagtcgt
       61 ccgaggcgcg gtgagcgcgg tggacgctga ggcgctgctg caggagtcca ggagccccgg
      121 tgtccctaga gcactcagca aggccccggt tctctgcagt ccctagagca gctcgcgatg
      181 gccccgcgca agaacgccaa gggcggcggc ggcaacagca gcagcagcgg cagcggctcg
      241 ggcagcggta gcccgagcac cggtagcagc ggtagcagca gtagccccgg ggcgcggaga
      301 gaggcaaagc acggaggaca caagaatggg cggagaggag gaatttccgg agggtccttt
      361 ttcacgtggt tcatggtcat tgcgttgctg ggcgtctgga catcggtggc cgtcgtgtgg
      421 tttgacctcg ttgattatga ggaagttcta ggaaagctag gagtctatga cgcagatggt
      481 gatggggact tcgatgtgga tgatgccaag gttttattag gccttaaaga aagatctact
      541 tccgagagga catttccacc ggaggaggca gagacacagg ccgagctgga ggagcaggcc
      601 cctgaggggg cagaagccca gaatgttgaa gatgaagtaa aagaacaaat tcagtccctt
      661 ctccaggaat cagtacacac agaccacgac ctcgaagcag atggaccagc aggagagcca
      721 cagtcagagg ttgaggactt cctcacggcc actgacagcg atgacagatt tgaggccctg
      781 gaacctggga cagttcatga agacaccgag gatagttatc atgtggaaga gacagcatcg
      841 cagaaccatc ccaacgatgc ggaagaggtg atgagtgaac aggaaagctc agatcacggt
      901 gaagcagtga cagacgatgg gttgcagcag cacgcagagg aagtaagaca tgaagactat
      961 gatgaaccag tatatgaacc ttcagaaaat gaaagaatag aaatttcaga taatgccatt
     1021 gatgattcca acatcatttc agaagaaata aatgtcgcct ccgtggaaga acagcaagac
     1081 acaccaccag ttaagaagaa gaagcccaaa cttctaaata aatttgataa aacaattaaa
     1141 gccgagctgg acgctgcaga aaagctccgg aaaaggggta aaatcgaaga agcagtgagt
     1201 gcatttgaag aattggttcg aaggtaccct cagagccctc gtgcaagata cggcaaagca
     1261 cagtgtgaag atgacttggc agagaagcag agaagcaatg aggttctgcg cagggccatt
     1321 gagacctacc aggaagcggc tagcctgcct gatgccccga cagacctggt gaagctgagc
     1381 ttgaagcgac ggtcagaaag acagcagttt ctaggtcaca tgaggggttc tctacttacc
     1441 ctccagagac tagttcagct gttccctagt gatacgacct taaaaaacga ccttggcgta
     1501 ggataccttt tgatgggaga caacgacagt gccaagaagg tttacgaaga ggtgctgaac
     1561 gtgacaccga atgatggctt cgcgaaagtg cattacggct tcatcctgaa ggcgcagaac
     1621 aggatagccg agagtattcc ctacttaaag gaaggaatcg aatccgggga ccctggcacg
     1681 gatgatggcc ggttttattt ccacttgggg gacgccatgc agagagtcgg gaacaaagag
     1741 gcatataagt ggtatgaact tgggcacaag agaggacatt ttgcctctgt ctggcagcgt
     1801 tctctttaca atgtgaatgg tctgaaggct cagccgtggt ggacacccag ggagactggc
     1861 tacacagagc tagtgaagtc tttagagaga aactggaagt taatccgaga cgaaggcctc
     1921 atggtgatgg ataaagccaa gggtctcttc ctgcctgagg atgaaaacct ccgggagaag
     1981 ggcgactgga gccagttcac actatggcag caaggaagga aaaatgagaa tgcctgtaaa
     2041 ggagctccta agacctgtac tttactagaa aagttttccg agacaacagg atgcagaaga
     2101 ggacagatca aatattccat catgcaccct ggaactcatg tgtggccaca cacaggaccc
     2161 acaaactgca ggctccgaat gcatctaggg ttggtgattc ccaaggaagg ctgcaagatc
     2221 aggtgtgcca atgagaccag gtcatgggaa gaaggcaagg tgctcatctt tgatgactct
     2281 tttgagcatg aggtttggca ggatgcctcg tctttccggc tgatatttat tgtggatgtg
     2341 tggcaccccg agctgacccc tcagcagagg cgtagccttc ctgcaatttg aaaggcatca
     2401 acacagactc ggttgctctc cagggaggcc gcctttccag ttccttttgg gtgtgcagat
     2461 agaagctcaa gtgccatgac tcttcacccc cttgccttgc agctgaagag ctctaaggtt
     2521 ccttctggat tagaactcac tggagggagt atttgccttc ctgcaattca tttaggagcc
     2581 cccttgcttc atggcaccca gaactggtgc ctggattgaa ggggaatact tggttgtgtt
     2641 gtctacatag ctggccaaag atatttttct acatagacta gtgtctacat caatgtacat
     2701 ggaggatata ctatatatag aaactgtgaa tgagtcactc tagtttgtaa tttttctatg
     2761 cagttatatt tttctaagta gctaaactat tctgtcacca cataccccca cgttttcatt
     2821 gactttaatg acaagaagta taaattcttt acttctaact gttaagtggt aattttcctg
     2881 gtaaattcag acatctccct tttggaaaaa gaaagccatg tatgaagaaa aggactttgt
     2941 tttcctaaca taaatgggaa gttataccgg gatgcgtgaa ctgtgccaac acttgccctt
     3001 gagtctacct gtgtatcttc atttatgctg agtgtcttcc tttttctctg tgctaataat
     3061 aggaagctct tgttgataaa ataccacaga tattggagct tggagagaaa aatattacat
     3121 gggagtgaaa cctcctgctc aagatcatgg gcccagacag cctggtccct tagccttctg
     3181 tatacaaggc ctggactctc cagtgtctgc gtactgtaga tccactagag tgtcaagaag
     3241 acggcctctt ggactctgag agtctcttca ctattttatc catgtaggaa ttgtagcata
     3301 ggaggtgctc agcaaaccta gcatcctagg tggtcgagca tgcttgatta tgaatttgca
     3361 gtgcttttcc gtcttcctcc ctcaaaatca tgtcagccat ctcactatat tttgaaacag
     3421 cgttttatgg gcgtgtttga tttgagcgct acccatgtct gagaaagagc aggagaaagt
     3481 catcttgctc ctcaagatga tcattagtga agcatggctg cattttattt tctattttca
     3541 aattaaggat aactcaaact ttagaatgta atgacattca tacactgatc acttctgcag
     3601 aaatggctgg aattccagcc acacaggtag ataaaatgga gatgcgggct tttgaaccaa
     3661 tgtcaaaaga agcagctttg tgtacctcat tgaaagagcc attcattaga aattgatctt
     3721 ttccctttta gcttaaggac ggctcttagt aggaaagttt acaaaatgtg tccattctta
     3781 aaataggcac ttgttccctc ttttgccagt gttcaaaaat tcctctaaaa cagatggcaa
     3841 aggcatgggg gaatacccaa tccttaccaa attctagaaa agaaaacaaa ttctcagaca
     3901 aaagaaaaag gttatttgtg ttcttcaata tttattaaac agaggaactc actgacaaaa
     3961 ggcaattcaa tccagtgttc atgaagtaac ccttggttac ctgctgggtt tggttctcct
     4021 atatattaca tacacataac gaaatgcaaa ccatatgttc tcattgttaa actatcacct
     4081 tacattcatg taataaaatg gtagaaatga gtgaaaatta gcttttaact tagtaattat
     4141 aacatgtttt ttaaaatatg gtcattacag caggattcta aatattgcct tgtgaaaagc
     4201 cagaagtacc attactatta caagtgttgg cagtaactga ctccaacagc attttgagta
     4261 cttggatccc acgtttatct tataaacaca agcaataaac aattttccaa ttcactttaa
     4321 tttttccttt ctcttgtgtc ataagaaaag aatttccatc catgtcttgg tagatatttt
     4381 tgaaggttct tattttatga ttcaaaaggt ctatacaaag tgaattggtg tattttatat
     4441 actatgatgc cattgtttgg gaaatacttt aaattctgtt tcgattttac ttcttcaagg
     4501 ttggaacata aaaatagctt ctgttactat tctctgccag tagaaaaaaa atgataaaac
     4561 agtagatcaa caaaggagta taaatctagg ctgtagctcg gggctcaggg gtagaacact
     4621 tgcctgacag gacaaggtcc tgggtttgat cttcagcact ggagggatac agggaagaca
     4681 gaggaacagg gagacagaga aagaaagaca aaggaaaaag agaaggggtg aggaggagaa
     4741 gggtaggaag gaacagggaa agagacagag aggaagaggc gggaatagag gaagggagac
     4801 aggaagagag caaagggcag gaataagaga agagaaacga agagaaggaa gtggtcacaa
     4861 ttagcaatgt tgtttgcgtg tttatggatg gaagtaagta gaattggttt cctgttttct
     4921 ttaggatgtt tagggtgtaa gtcaacctac caaatgctta aaatgtaaag tattttaata
     4981 agtgttatta attaaaattt ttgacattaa gcactctggt catattagta agtgttgtct
     5041 ttgtcagaga gttggctagg gaataagata cctacgtata ctcaactggc cttgggaaac
     5101 atgacacaga taaaatatcc taccctatga tgttttccga cttcctttga gtggggactg
     5161 gggtccattt ctcaggagaa tggataagga aataggttgt ctttggcatt tcatcttgca
     5221 ttcttggtcc tctttagctt ggtacttaca tgctgagcca tccttaagtg tcttcctgtg
     5281 agatttgact ccctgccccc tcagagcctt tctccacagg taatgggagg gttgggacaa
     5341 agtgacttat ttgctagcac tttttttttt tttttttttt tttggccata gtaacccaag
     5401 aactaactta aatggactca tcagtcacaa tgacacaatg agttgcctcc tctctgtagc
     5461 catgcctaca ggaaatcact ttgttatgat gaagcagtca ttcttttcac actgccccgt
     5521 gtcttcttaa aaaaaaaaaa aaaaacacgg ttcatgaagt cagctgaagt cctgacaaac
     5581 accatgatgt caaaatcatt cttgcgggat agatatgtaa attaaaaacg ttgtgaatag
     5641 ccagacctgc gagatcacgc ccttaggctg agcacactta gatgctggtg atgaggtcag
     5701 aaaataagtc agtacaactg gaaattatag tagctacagt tgcctggggt tcgggactac
     5761 tttaagcttg ctgactgaca acgtctgcac agtttaactc tgttgtattt atttgggaat
     5821 gcattcatct tacttcgcaa agcctggaga gagttcctgt gtgaatcctt agagcgatgt
     5881 atatgcggct aatttaggtt cccccccccc tttttaagta gatttgctgc cataaatagg
     5941 aggggaggga gaatcctttt tacataaatg cctttcttca tccccccacc atccctcact
     6001 aaaacataaa ttaattagtt acattttaaa agcatctctc agatccttgt ccagtgtggg
     6061 ctgcccagac caatggctgc tgacagtcat ggctgggcct ggaatggagg acgtcatatc
     6121 aagcagagca cacatgtctg gaggtcagtg gcacaggctt gctaggtggc tgctccactg
     6181 gaggagtcgc atgatgctgg ctcagtccag agccagcagt ggctgggtgt tctcgttttc
     6241 ccccttctct tcatgtttca aggtcccagc ttctaccacg gactgagatc taatgagaga
     6301 gagagagaga gagagaaaga gagagagagg agacgcacac agtcacagac agtccatgtt
     6361 gtgattcccc tggaaaatcc aagcatgtaa gatagctact tagtacttcc tgtttggtac
     6421 ctgttttcca cacaccactt tatttatttc tttcctttat ctttcggaag attgaacctg
     6481 gtcattctga gactctttcc ttctcttgaa tttgatccat acctttttgc tgtaataaac
     6541 cacagctgtg agtgtaacat tttgtcaatg tttccatcta tcgaataaaa ataaaagcat
     6601 tcccataaat gc
//
