LOCUS       NM_144750               2524 bp    mRNA    linear   ROD 06-JUN-2024
DEFINITION  Rattus norvegicus asparaginase (Aspg), mRNA.
ACCESSION   NM_144750
VERSION     NM_144750.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2524)
  AUTHORS   Sugimoto,H. and Yamashita,S.
  TITLE     Characterization of the transacylase activity of rat liver 60-kDa
            lysophospholipase-transacylase. Acyl transfer from the sn-2 to the
            sn-1 position
  JOURNAL   Biochim Biophys Acta 1438 (2), 264-272 (1999)
   PUBMED   10320809
REFERENCE   2  (bases 1 to 2524)
  AUTHORS   Sugimoto,H., Odani,S. and Yamashita,S.
  TITLE     Cloning and expression of cDNA encoding rat liver 60-kDa
            lysophospholipase containing an asparaginase-like region and
            ankyrin repeat
  JOURNAL   J Biol Chem 273 (20), 12536-12542 (1998)
   PUBMED   9575212
REFERENCE   3  (bases 1 to 2524)
  AUTHORS   Sugimoto,H. and Yamashita,S.
  TITLE     Purification, characterization, and inhibition by phosphatidic acid
            of lysophospholipase transacylase from rat liver
  JOURNAL   J Biol Chem 269 (8), 6252-6258 (1994)
   PUBMED   8119970
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AB009372.1.
            
            On Aug 31, 2012 this sequence version replaced NM_144750.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AB009372.1, BC098655.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132291, SAMD00132292
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-2524              AB009372.1         2-2525
FEATURES             Location/Qualifiers
     source          1..2524
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="6"
                     /map="6q32"
     gene            1..2524
                     /gene="Aspg"
                     /note="asparaginase"
                     /db_xref="GeneID:246266"
                     /db_xref="RGD:708388"
     exon            1..160
                     /gene="Aspg"
                     /inference="alignment:Splign:2.1.0"
     CDS             79..1773
                     /gene="Aspg"
                     /EC_number="3.1.1.5"
                     /EC_number="3.1.1.47"
                     /EC_number="3.5.1.1"
                     /note="lysophospholipase; asparaginase homolog;
                     lysophospholipase-transacylase"
                     /codon_start=1
                     /product="60 kDa lysophospholipase"
                     /protein_id="NP_653351.1"
                     /db_xref="GeneID:246266"
                     /db_xref="RGD:708388"
                     /translation="MARATGPEQRLLAIYTGGTIGMRSEGGVLVPGRGLAAVLRTLHM
                     LHDEEYARAHSLPEDTLVLPPASSDQRIIYKVLECQPLFDSSDMTITEWVQIAQTIER
                     HYTQYQGFVVIHGTDTMAFAASVLSFMLENLQKPVILTGAQVPIHELWSDGRENLLGA
                     LLMAGQYVIPEVCLFFQNQLFRGNRTTKVDARRFAAFCSPNLPPLATVGADVTINREL
                     VRKASWKSHLVVHSNMEPDVGLLRLYPGIPASLVRTFLQPPLKGVVMETFGSGNGPTK
                     PDLIQELRAAAERGLIIVNCTHCLQGAVTSDYAPGMAMAGAGIISGFDMTSEAALAKL
                     SYVLGQPGLSLSDRKKLLAKDLRGEMTLPTTDDLLGDDMLGCRATWLLSMNGSQDADA
                     MKDVLLPGLALAAAHAGDLDTLQAFVELGRDLNLKDYSGQTPLHVAARRGHASVVAML
                     LQKGVDVDACNEDGQSPLLLAVRGRHQSVIRLLRAAGAHLSPQELEDVGTELCRLASR
                     ADSEGLRAWWQAGADLGQPDYDGHCALQVAEAAGNADVVALLQSLEDRVSAQPQPH"
     exon            161..269
                     /gene="Aspg"
                     /inference="alignment:Splign:2.1.0"
     exon            270..381
                     /gene="Aspg"
                     /inference="alignment:Splign:2.1.0"
     exon            382..507
                     /gene="Aspg"
                     /inference="alignment:Splign:2.1.0"
     exon            508..591
                     /gene="Aspg"
                     /inference="alignment:Splign:2.1.0"
     exon            592..718
                     /gene="Aspg"
                     /inference="alignment:Splign:2.1.0"
     exon            719..831
                     /gene="Aspg"
                     /inference="alignment:Splign:2.1.0"
     exon            832..1014
                     /gene="Aspg"
                     /inference="alignment:Splign:2.1.0"
     exon            1015..1128
                     /gene="Aspg"
                     /inference="alignment:Splign:2.1.0"
     exon            1129..1242
                     /gene="Aspg"
                     /inference="alignment:Splign:2.1.0"
     exon            1243..1338
                     /gene="Aspg"
                     /inference="alignment:Splign:2.1.0"
     exon            1339..1502
                     /gene="Aspg"
                     /inference="alignment:Splign:2.1.0"
     exon            1503..1589
                     /gene="Aspg"
                     /inference="alignment:Splign:2.1.0"
     exon            1590..1689
                     /gene="Aspg"
                     /inference="alignment:Splign:2.1.0"
     exon            1690..2524
                     /gene="Aspg"
                     /inference="alignment:Splign:2.1.0"
     polyA_site      2524
                     /gene="Aspg"
                     /note="14 a nucleotides"
ORIGIN      
        1 caccctgcgg gctcctccgc ttcccggtct tgctttccct ttggctctgt ccccactgag
       61 gagtccgctg tcccagccat ggcgcgtgct accggacccg agcagcggct gctggccatc
      121 tacactggcg gcaccatcgg catgcggagt gaaggcggag tgctggtacc tgggagaggc
      181 ctggctgctg tcctgaggac acttcacatg ctccacgatg aagagtatgc cagagcccac
      241 agcctgcccg aggatacgct ggtgttgccc ccggccagtt ctgaccagag gatcatctac
      301 aaggtgctgg agtgccagcc actcttcgac tccagtgaca tgaccatcac tgaatgggtt
      361 cagattgccc aaacgataga gagacactac acacagtacc agggctttgt ggtcatccac
      421 ggcacggaca ccatggcctt tgctgcgtca gtgctctctt tcatgctgga aaacctgcag
      481 aaaccggtca tcctcacagg tgcccaggtt cctatccacg aactgtggag tgatggccgt
      541 gagaacctgc tgggggctct gctcatggct ggccagtacg tcatccctga ggtctgcctg
      601 ttcttccaga atcagctctt tcggggcaat cggacaacca aggtggacgc tcggagattt
      661 gcggccttct gctcccctaa cctgccccct ctagccactg tgggcgcaga cgtaacaatc
      721 aaccgtgagc tggtacggaa ggccagttgg aagagccacc tggtggtcca cagcaacatg
      781 gagcctgatg tgggcctact gcgcctctac cctgggattc ccgcctccct ggtccggacc
      841 ttcctccagc ccccactgaa gggcgtggtc atggagacct ttggctccgg gaatgggccc
      901 accaagccgg acctaataca ggagctccgg gcggcggccg aaagaggcct gatcattgtc
      961 aactgtaccc attgccttca gggggctgtg acttccgact atgcacctgg gatggccatg
     1021 gcaggagccg gcataatctc aggcttcgac atgacatcag aagctgccct ggccaaactg
     1081 tcctatgtgc tgggccagcc agggctgagc ctgagtgaca ggaagaagct gctggccaag
     1141 gatcttcgcg gggagatgac actgcctaca acagatgact tgctgggaga tgacatgctg
     1201 ggctgcaggg ccacatggct tctcagtatg aatggcagcc aggatgccga tgccatgaag
     1261 gatgttctgc tgcccggcct ggccctggct gcagctcatg ctggtgacct ggacactctg
     1321 caggcctttg tggagctggg cagagacctc aacctgaagg actacagtgg ccagacgcca
     1381 ctgcatgtgg ctgcacggag agggcatgct tcagtggtcg ccatgctact gcagaagggt
     1441 gtggatgtgg atgcctgtaa tgaggacggt cagagcccac tgctgctggc cgtgaggggc
     1501 aggcatcaga gtgtcatcag gctgctgagg gccgctgggg ctcacctgtc tccccaggag
     1561 ctggaggacg tggggacaga gctgtgcagg ctggcatcaa gggcggacag cgaaggcctg
     1621 cgggcgtggt ggcaggctgg ggctgaccta ggacagccgg actatgatgg acactgtgcc
     1681 ctgcaagttg ctgaagcagc agggaatgca gatgtggtgg ctctgctgca gagtcttgag
     1741 gacagggtca gcgcccagcc ccagccccat tagttcttgg gctggtctga tgcctcctca
     1801 gtgaactctc attggtttac gactggatcc tggcaccaga gccagttctg gagacggcta
     1861 gaggaagtgg gcataagaga tgggtcattc gtccagagcc cttcttgggg accccgagag
     1921 taaacacggt cttcgggaga tagggctggt ggggcttcgt gtagaagccc agctcagacc
     1981 ttcaccctac ccagtctgga gctgattgac tggaaggacc taggcctgct cccagctgac
     2041 atccatcccc actgctctgg agttttgagg cttggcggac tatcctcaac tcctgggact
     2101 gcctggattc catacacaag gcttctgggg tggagtacgg ggaggcctgc cctggatgca
     2161 tccctgtagt cctcggaaga ccttgtttcc aggaagtgct ccttggcccc caacctgttg
     2221 cagcaggagc tgtgtcttac tgcccgtggg acctcacgca cataccagca gactggctgc
     2281 tatgttagca ccattctagt tggtgagacc tcgaagcttt cagaagccag ctctgttctg
     2341 gccttgttat ctcctgcagc caggtgtccc aggagctgac tcagagctat ggactcctcc
     2401 tccctaagtt gcgggggcgg gggggggggt cgtcttctgc taaactgctt cccagcctgt
     2461 tggcatgaca aatctggagg tctttgttga gtagaatgtc aataaagcca tccggacagc
     2521 tgct
//
