LOCUS       NM_017189               1381 bp    mRNA    linear   ROD 31-MAR-2024
DEFINITION  Rattus norvegicus asialoglycoprotein receptor 2 (Asgr2), mRNA.
ACCESSION   NM_017189
VERSION     NM_017189.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1381)
  AUTHORS   Alam,I., Sun,Q., Koller,D.L., Liu,L., Liu,Y., Edenberg,H.J.,
            Foroud,T. and Turner,C.H.
  TITLE     Genes influencing spinal bone mineral density in inbred F344, LEW,
            COP, and DA rats
  JOURNAL   Funct Integr Genomics 10 (1), 63-72 (2010)
   PUBMED   19841953
REFERENCE   2  (bases 1 to 1381)
  AUTHORS   Kamhi-Nesher,S., Shenkman,M., Tolchinsky,S., Fromm,S.V., Ehrlich,R.
            and Lederkremer,G.Z.
  TITLE     A novel quality control compartment derived from the endoplasmic
            reticulum
  JOURNAL   Mol Biol Cell 12 (6), 1711-1723 (2001)
   PUBMED   11408579
REFERENCE   3  (bases 1 to 1381)
  AUTHORS   Rivkin,E., Tres,L.L., Kaplan-Kraicer,R., Shalgi,R. and
            Kierszenbaum,A.L.
  TITLE     Molecular cloning of rat sperm galactosyl receptor, a C-type lectin
            with in vitro egg binding activity
  JOURNAL   Mol Reprod Dev 56 (3), 401-411 (2000)
   PUBMED   10862008
REFERENCE   4  (bases 1 to 1381)
  AUTHORS   Ishibashi,S., Hammer,R.E. and Herz,J.
  TITLE     Asialoglycoprotein receptor deficiency in mice lacking the minor
            receptor subunit
  JOURNAL   J Biol Chem 269 (45), 27803-27806 (1994)
   PUBMED   7961705
REFERENCE   5  (bases 1 to 1381)
  AUTHORS   Sanford,J.P., Elliott,R.W. and Doyle,D.
  TITLE     Asialoglycoprotein receptor genes are linked on chromosome 11 in
            the mouse
  JOURNAL   DNA 7 (10), 721-728 (1988)
   PUBMED   3234178
REFERENCE   6  (bases 1 to 1381)
  AUTHORS   Halberg,D.F., Wager,R.E., Farrell,D.C., Hildreth,J. 4th,
            Quesenberry,M.S., Loeb,J.A., Holland,E.C. and Drickamer,K.
  TITLE     Major and minor forms of the rat liver asialoglycoprotein receptor
            are independent galactose-binding proteins. Primary structure and
            glycosylation heterogeneity of minor receptor forms
  JOURNAL   J Biol Chem 262 (20), 9828-9838 (1987)
   PUBMED   3597443
REFERENCE   7  (bases 1 to 1381)
  AUTHORS   McPhaul,M. and Berg,P.
  TITLE     Identification and characterization of cDNA clones encoding two
            homologous proteins that are part of the asialoglycoprotein
            receptor
  JOURNAL   Mol Cell Biol 7 (5), 1841-1847 (1987)
   PUBMED   3600647
REFERENCE   8  (bases 1 to 1381)
  AUTHORS   Drickamer,K., Mamon,J.F., Binns,G. and Leung,J.O.
  TITLE     Primary structure of the rat liver asialoglycoprotein receptor.
            Structural evidence for multiple polypeptide species
  JOURNAL   J Biol Chem 259 (2), 770-778 (1984)
   PUBMED   6319386
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from
            JAXUCZ010000010.1.
            
            On Nov 27, 2020 this sequence version replaced NM_017189.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: J02762.1, BC088099.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760400, SAMEA5760476
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-139               JAXUCZ010000010.1  55320109-55320247
            140-295             JAXUCZ010000010.1  55320567-55320722
            296-412             JAXUCZ010000010.1  55325160-55325276
            413-508             JAXUCZ010000010.1  55325533-55325628
            509-580             JAXUCZ010000010.1  55326220-55326291
            581-667             JAXUCZ010000010.1  55326410-55326496
            668-813             JAXUCZ010000010.1  55326583-55326728
            814-920             JAXUCZ010000010.1  55332479-55332585
            921-1381            JAXUCZ010000010.1  55332827-55333287
FEATURES             Location/Qualifiers
     source          1..1381
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="10"
                     /map="10q24"
     gene            1..1381
                     /gene="Asgr2"
                     /note="asialoglycoprotein receptor 2"
                     /db_xref="GeneID:29403"
                     /db_xref="RGD:2161"
     exon            1..139
                     /gene="Asgr2"
                     /inference="alignment:Splign:2.1.0"
     exon            140..295
                     /gene="Asgr2"
                     /inference="alignment:Splign:2.1.0"
     CDS             172..1077
                     /gene="Asgr2"
                     /note="RHL-2; ASGPR 2; ASGP-R 2; hepatic lectin R2/3;
                     HL-2; hepatic lectin 2, RHL2"
                     /codon_start=1
                     /product="asialoglycoprotein receptor 2"
                     /protein_id="NP_058885.1"
                     /db_xref="GeneID:29403"
                     /db_xref="RGD:2161"
                     /translation="MEKDFQDIQQLDSEENDHQLIGDEEQGSHVQNLRTENPRWGGQP
                     PSRPFPQRLCSKFRLSLLALAFNILLLVVICVVSSQSMQLQKEFWTLKETLSNFSTTT
                     LMEFKALDSHGGSRNDNLTSWETILEKKQKDIKADHSTLLFHLKHFPLDLRTLTCQLA
                     FFLSNGTECCPVNWVEFGGSCYWFSRDGLTWAEADQYCQMENAHLLVINSREEQEFVV
                     KHRGAFHIWIGLTDKDGSWKWVDGTEYRSNFKNWAFTQPDNWQGHEEGGSEDCAEILS
                     DGLWNDNFCQQVNRWACERKRDITY"
     exon            296..412
                     /gene="Asgr2"
                     /inference="alignment:Splign:2.1.0"
     exon            413..508
                     /gene="Asgr2"
                     /inference="alignment:Splign:2.1.0"
     exon            509..580
                     /gene="Asgr2"
                     /inference="alignment:Splign:2.1.0"
     exon            581..667
                     /gene="Asgr2"
                     /inference="alignment:Splign:2.1.0"
     exon            668..813
                     /gene="Asgr2"
                     /inference="alignment:Splign:2.1.0"
     exon            814..920
                     /gene="Asgr2"
                     /inference="alignment:Splign:2.1.0"
     exon            921..1381
                     /gene="Asgr2"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cattcagaca ggcctcttgc ctagatcagc cccctcctcc ttctcgcctg ctgtcctgct
       61 gtcccaggtt taacccctct ttctccttgg actcaggctg cctccggaag ccagagtcag
      121 ctctctatac atttaacagt cccagatctg tctccagcct gagggcccat catggagaag
      181 gactttcaag atatccagca gctggactct gaggaaaacg accatcagct cattggcgat
      241 gaggaacaag gctctcatgt gcagaatctt aggacagaaa atccacgttg gggaggacag
      301 cctccttcca ggccctttcc acagcgcctc tgctccaagt tccgcctcag tctgctcgcc
      361 ctggccttca acattctcct gctggtggtc atctgtgtgg tttcatccca aagcatgcag
      421 ctgcaaaagg agttctggac cctgaaagaa accttgagca acttctccac caccaccctg
      481 atggagttca aggctctgga ctcccacgga ggtagcagga atgacaactt gacttcttgg
      541 gaaaccatac tggagaaaaa gcagaaggac ataaaagcag atcactccac gctgctcttc
      601 cacctgaagc acttccccct ggatctgcga accctgacct gtcagctggc gttcttcctg
      661 agcaacggca cagaatgctg ccccgttaac tgggtggagt ttggtggaag ctgctactgg
      721 ttttctcggg atgggctcac ctgggctgag gctgaccagt actgccaaat ggagaatgcc
      781 catctgctgg tcatcaactc cagggaggag caggaattcg ttgtaaagca caggggcgcg
      841 tttcacattt ggataggtct caccgacaag gatggctcct ggaaatgggt ggatgggacg
      901 gaatatagaa gtaacttcaa gaattgggct ttcactcagc cagataactg gcagggccat
      961 gaagaggggg gaagtgaaga ctgtgctgaa atcctgtcag atggcctctg gaatgacaac
     1021 ttctgccagc aggtgaaccg ctgggcttgt gaaaggaaac gggacatcac ctactaggag
     1081 tctgctctac tatgtctttg tcaaccctcc ccccaacccc cgcatcactc attaggagtc
     1141 tgctctacca tgtctctgcc ccaccccatc accgcatcac cccaacattt tcactgggga
     1201 tattggagca agaaagagag acagagtccc aggcatgagg ggggttatgg gagaatggaa
     1261 agggggtggc tctatggtct catacgttag gaagactgag attccacccc tcttcacaac
     1321 ttattacaat tgttataaat ttcaacaatg gagtaggaaa gaaaaaaata aacaatacca
     1381 g
//
