LOCUS       NM_001106389            2693 bp    mRNA    linear   ROD 30-MAR-2024
DEFINITION  Rattus norvegicus anti-silencing function 1A histone chaperone
            (Asf1a), mRNA.
ACCESSION   NM_001106389 XM_001059946 XM_215389
VERSION     NM_001106389.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2693)
  AUTHORS   Wajapeyee,N., Malonia,S.K., Palakurthy,R.K. and Green,M.R.
  TITLE     Oncogenic RAS directs silencing of tumor suppressor genes through
            ordered recruitment of transcriptional repressors
  JOURNAL   Genes Dev 27 (20), 2221-2226 (2013)
   PUBMED   24105743
REFERENCE   2  (bases 1 to 2693)
  AUTHORS   Burgess,R.J. and Zhang,Z.
  TITLE     Histone chaperones in nucleosome assembly and human disease
  JOURNAL   Nat Struct Mol Biol 20 (1), 14-22 (2013)
   PUBMED   23288364
  REMARK    Review article
REFERENCE   3  (bases 1 to 2693)
  AUTHORS   Song,T.Y., Yang,J.H., Park,J.Y., Song,Y., Han,J.W., Youn,H.D. and
            Cho,E.J.
  TITLE     The role of histone chaperones in osteoblastic differentiation of
            C2C12 myoblasts
  JOURNAL   Biochem Biophys Res Commun 423 (4), 726-732 (2012)
   PUBMED   22705305
REFERENCE   4  (bases 1 to 2693)
  AUTHORS   Fernandez-Tenorio,M., Porras-Gonzalez,C., Castellano,A., Del
            Valle-Rodriguez,A., Lopez-Barneo,J. and Urena,J.
  TITLE     Metabotropic regulation of RhoA/Rho-associated kinase by L-type
            Ca2+ channels: new mechanism for depolarization-evoked mammalian
            arterial contraction
  JOURNAL   Circ Res 108 (11), 1348-1357 (2011)
   PUBMED   21493898
REFERENCE   5  (bases 1 to 2693)
  AUTHORS   Tagami,H., Ray-Gallet,D., Almouzni,G. and Nakatani,Y.
  TITLE     Histone H3.1 and H3.3 complexes mediate nucleosome assembly
            pathways dependent or independent of DNA synthesis
  JOURNAL   Cell 116 (1), 51-61 (2004)
   PUBMED   14718166
REFERENCE   6  (bases 1 to 2693)
  AUTHORS   Mello,J.A., Sillje,H.H., Roche,D.M., Kirschner,D.B., Nigg,E.A. and
            Almouzni,G.
  TITLE     Human Asf1 and CAF-1 interact and synergize in a repair-coupled
            nucleosome assembly pathway
  JOURNAL   EMBO Rep 3 (4), 329-334 (2002)
   PUBMED   11897662
REFERENCE   7  (bases 1 to 2693)
  AUTHORS   Munakata,T., Adachi,N., Yokoyama,N., Kuzuhara,T. and Horikoshi,M.
  TITLE     A human homologue of yeast anti-silencing factor has histone
            chaperone activity
  JOURNAL   Genes Cells 5 (3), 221-233 (2000)
   PUBMED   10759893
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000020.1.
            
            On or before Nov 21, 2008 this sequence version replaced
            XM_001059946.1, XM_215389.4.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BF408417.1, SRR26643298.78818.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760386
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-175               JAXUCZ010000020.1  33436632-33436806
            176-291             JAXUCZ010000020.1  33442057-33442172
            292-468             JAXUCZ010000020.1  33445864-33446040
            469-2693            JAXUCZ010000020.1  33449254-33451478
FEATURES             Location/Qualifiers
     source          1..2693
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="20"
                     /map="20q11"
     gene            1..2693
                     /gene="Asf1a"
                     /note="anti-silencing function 1A histone chaperone"
                     /db_xref="GeneID:294408"
                     /db_xref="RGD:1311941"
     exon            1..175
                     /gene="Asf1a"
                     /inference="alignment:Splign:2.1.0"
     CDS             67..681
                     /gene="Asf1a"
                     /note="ASF1 anti-silencing function 1 homolog A"
                     /codon_start=1
                     /product="histone chaperone ASF1A"
                     /protein_id="NP_001099859.1"
                     /db_xref="GeneID:294408"
                     /db_xref="RGD:1311941"
                     /translation="MAKVQVNNVVVLDNPSPFYNPFQFEITFECIEDLSEDLEWKIIY
                     VGSAESEEYDQVLDSVLVGPVPAGRHMFVFQADAPNAGLIPDADAVGVTVVLITCTYR
                     GQEFIRVGYYVNNEYTETELRENPPVKPDFSKLQRNILASNPRVTRFHINWEDNTEKL
                     EDAESSDPNLQSLLSTDALPSASKGWATSENSLSVMLESHMDCM"
     exon            176..291
                     /gene="Asf1a"
                     /inference="alignment:Splign:2.1.0"
     exon            292..468
                     /gene="Asf1a"
                     /inference="alignment:Splign:2.1.0"
     exon            469..2693
                     /gene="Asf1a"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gcggccgcgc gcgggactct gtggtgccgc cagccccggc cccattgttt gtgttttctt
       61 caaaatatgg caaaggttca ggtgaacaat gtagtggtgc tggataaccc gtcgcctttc
      121 tacaacccgt tccagttcga gatcaccttc gagtgcatcg aggacctgtc tgaagacttg
      181 gagtggaaaa ttatctacgt gggctctgct gaaagtgaag aatacgatca agttttagac
      241 tctgtgttag tgggtcctgt tcctgcaggc aggcatatgt ttgtgtttca ggctgatgcg
      301 ccaaacgcgg ggctcatccc agacgcagac gcagtggggg taacagttgt actgattacc
      361 tgcacctacc gaggtcaaga atttattaga gttggctact atgtaaataa tgaatatact
      421 gaaacagaat taagggaaaa cccaccagta aaaccagact tttctaagct tcaaaggaat
      481 attttggctt ctaatcccag agtcacaagg ttccacatta actgggaaga taacacagag
      541 aaactggaag acgcagagag cagtgacccc aatctgcagt cccttctttc cacagatgca
      601 ctgccttcag catcaaaggg atgggcgacg tcagaaaact cactcagtgt catgttagaa
      661 tcccacatgg actgcatgtg acacgtgcca tgccattagt acagattaag ctattaaaac
      721 agaactatct ccctgaagtt ccgtaagtac atagtcaacg tgaaatgtga agaatttgtt
      781 taaaaacatc ctgtagaaag tttataagaa aaccagtatt tgagcaaatt gtggaatata
      841 aatacaacta tttttaagga ctttttttct ctaatgtgtt attttatttg ttcatgaaac
      901 taatctgatt aaagcatata tattattttc ttctctttta tatgtaatta aagcacttat
      961 aaaaagaaaa gttatcaatt cttagactgg gttgtaaagg tgttttagcc tcttggacaa
     1021 taagatttat cagcttttaa aaggacaaag tttacttcaa ctaaaatgat ttttcctgtg
     1081 aagatagtat ccttataatt tgacaagaaa atttccattc tgtagtaaaa aagatagatt
     1141 taaaatggga tttgaaatca atcacatgcc accagggttt ttctaggcca tcccagtgca
     1201 tcttactaca gttcacatta aactggactt ctagttttta tataacaaat gcggctgcct
     1261 ttgaagtcct tctgactatc gtgtatgctt tcctacatct aaaactgaga aactatgatc
     1321 ctaagccatc actgtctaga gagtccaaca cataagagca aacataaggt ctctgaagtg
     1381 taagactcca ttatgatggc tcagatctgc tcactctttc tgcttacagg aatgctgaac
     1441 gtgcgttgct ggcaccatta ctattgaagg gtgatttagg aaggtctagt cagcttcatc
     1501 ctggctagcg actctagaga gtatgtctta ccttttgcag ccacactacc ccatatcctt
     1561 tggttctcat aatgtgtaag atcagggcat tatctgtagt taacataaca gcttaaccac
     1621 tttttttttt ctcagaagaa tagttttaga aaggaattca ccaaataaat gggccaaaag
     1681 cttattttct ttaatgagaa gtaaatcctc aaagttttga tccattaaat tgacagtaca
     1741 atattctcag ttgttatcag tgatgatgcc caggatagcc ataggttcaa gttatgcagt
     1801 gccttcacat ctaagctttt atactgcact ttcaaaagca ttttgaggaa aaggaagggg
     1861 tatttattta aatacagact ctataagttg taatatattt cttgcttttt ttaaaagata
     1921 aatttgtgaa acaaagtctt gttaaatgtt aaactttgaa atttaagact ccatattacc
     1981 cagttcatag attttaaaaa taaatatttc tggctactaa aatgatttga aaaaaaaatc
     2041 tcattttgtc taactacaat taggagaaaa tgtttaagac agttcagtga tcagtacagt
     2101 aagaataagt ttgtcagaaa taaagataat taaatcacca agtaaagcaa ctcagtgcag
     2161 tcttagatta tagaaccact ttgtgatgac atgcttaggt ctttatacca aactttaaat
     2221 atatggccca tagtcacaaa agtcggagaa ataaaatact gccttttatt atttaaatgc
     2281 aatagcattt aaatttaaaa gtgaaagaag aatagaaaca tttacacatt aagaactaag
     2341 aaactagcat gcagggattt tcctcctgat tagcctcatt taaaaagaca ttatgtctga
     2401 attacagtta aaaggcttat agactccgct ccaccccact tcttttgaga tatggtctct
     2461 caacatagcc ctggctgtcc tgaactttcc ttagaccagt gtagccttca gctcacagac
     2521 atccacctgc ttctgcctcc tgagagctgg gattaaaggc attcgactcc acaccctgca
     2581 ccacttcctt gtttctatca gtataaataa atgtctggtg aatacgtaca catacaacac
     2641 acacatatgc acacacacag tccacaccgc tgaagagcta ggggagtagg tta
//
