LOCUS       NM_001277057            7446 bp    mRNA    linear   ROD 31-MAR-2024
DEFINITION  Rattus norvegicus activating signal cointegrator 1 complex subunit
            3 (Ascc3), mRNA.
ACCESSION   NM_001277057 XM_003751984 XM_003753497
VERSION     NM_001277057.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 7446)
  AUTHORS   Baltz,A.G., Munschauer,M., Schwanhausser,B., Vasile,A.,
            Murakawa,Y., Schueler,M., Youngs,N., Penfold-Brown,D., Drew,K.,
            Milek,M., Wyler,E., Bonneau,R., Selbach,M., Dieterich,C. and
            Landthaler,M.
  TITLE     The mRNA-bound proteome and its global occupancy profile on
            protein-coding transcripts
  JOURNAL   Mol Cell 46 (5), 674-690 (2012)
   PUBMED   22681889
REFERENCE   2  (bases 1 to 7446)
  AUTHORS   Dango,S., Mosammaparast,N., Sowa,M.E., Xiong,L.J., Wu,F., Park,K.,
            Rubin,M., Gygi,S., Harper,J.W. and Shi,Y.
  TITLE     DNA unwinding by ASCC3 helicase is coupled to ALKBH3-dependent DNA
            alkylation repair and cancer cell proliferation
  JOURNAL   Mol Cell 44 (3), 373-384 (2011)
   PUBMED   22055184
REFERENCE   3  (bases 1 to 7446)
  AUTHORS   Ghosh,D., Lippert,D., Krokhin,O., Cortens,J.P. and Wilkins,J.A.
  TITLE     Defining the membrane proteome of NK cells
  JOURNAL   J Mass Spectrom 45 (1), 1-25 (2010)
   PUBMED   19946888
REFERENCE   4  (bases 1 to 7446)
  AUTHORS   Jung,D.J., Sung,H.S., Goo,Y.W., Lee,H.M., Park,O.K., Jung,S.Y.,
            Lim,J., Kim,H.J., Lee,S.K., Kim,T.S., Lee,J.W. and Lee,Y.C.
  TITLE     Novel transcription coactivator complex containing activating
            signal cointegrator 1
  JOURNAL   Mol Cell Biol 22 (14), 5203-5211 (2002)
   PUBMED   12077347
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000020.1.
            
            On or before Mar 2, 2013 this sequence version replaced
            XM_003753497.1, XM_003751984.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643297.53785.1,
                                           SRR26360190.1797524.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760386
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-190               JAXUCZ010000020.1  55092383-55092572
            191-321             JAXUCZ010000020.1  55110970-55111100
            322-472             JAXUCZ010000020.1  55113852-55114002
            473-1032            JAXUCZ010000020.1  55124362-55124921
            1033-1153           JAXUCZ010000020.1  55155834-55155954
            1154-1361           JAXUCZ010000020.1  55162081-55162288
            1362-1503           JAXUCZ010000020.1  55163091-55163232
            1504-1629           JAXUCZ010000020.1  55163799-55163924
            1630-1830           JAXUCZ010000020.1  55169891-55170091
            1831-1971           JAXUCZ010000020.1  55170560-55170700
            1972-2136           JAXUCZ010000020.1  55171432-55171596
            2137-2313           JAXUCZ010000020.1  55182810-55182986
            2314-2385           JAXUCZ010000020.1  55188636-55188707
            2386-2520           JAXUCZ010000020.1  55211870-55212004
            2521-2712           JAXUCZ010000020.1  55222293-55222484
            2713-2937           JAXUCZ010000020.1  55222786-55223010
            2938-3057           JAXUCZ010000020.1  55229879-55229998
            3058-3222           JAXUCZ010000020.1  55232848-55233012
            3223-3309           JAXUCZ010000020.1  55234900-55234986
            3310-3486           JAXUCZ010000020.1  55235969-55236145
            3487-3712           JAXUCZ010000020.1  55240123-55240348
            3713-3867           JAXUCZ010000020.1  55241906-55242060
            3868-3966           JAXUCZ010000020.1  55244786-55244884
            3967-4135           JAXUCZ010000020.1  55246034-55246202
            4136-4356           JAXUCZ010000020.1  55246707-55246927
            4357-4442           JAXUCZ010000020.1  55250577-55250662
            4443-4609           JAXUCZ010000020.1  55252180-55252346
            4610-4755           JAXUCZ010000020.1  55253006-55253151
            4756-4876           JAXUCZ010000020.1  55253242-55253362
            4877-5019           JAXUCZ010000020.1  55255605-55255747
            5020-5157           JAXUCZ010000020.1  55267895-55268032
            5158-5278           JAXUCZ010000020.1  55268122-55268242
            5279-5411           JAXUCZ010000020.1  55269281-55269413
            5412-5537           JAXUCZ010000020.1  55273435-55273560
            5538-5649           JAXUCZ010000020.1  55288690-55288801
            5650-5784           JAXUCZ010000020.1  55288969-55289103
            5785-6009           JAXUCZ010000020.1  55333864-55334088
            6010-6161           JAXUCZ010000020.1  55350414-55350565
            6162-6309           JAXUCZ010000020.1  55352210-55352357
            6310-6519           JAXUCZ010000020.1  55355225-55355434
            6520-6695           JAXUCZ010000020.1  55367532-55367707
            6696-7446           JAXUCZ010000020.1  55371624-55372374
FEATURES             Location/Qualifiers
     source          1..7446
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="20"
                     /map="20q13"
     gene            1..7446
                     /gene="Ascc3"
                     /gene_synonym="Helic1"
                     /note="activating signal cointegrator 1 complex subunit 3"
                     /db_xref="GeneID:309887"
                     /db_xref="RGD:1307995"
     exon            1..190
                     /gene="Ascc3"
                     /gene_synonym="Helic1"
                     /inference="alignment:Splign:2.1.0"
     exon            191..321
                     /gene="Ascc3"
                     /gene_synonym="Helic1"
                     /inference="alignment:Splign:2.1.0"
     CDS             232..6837
                     /gene="Ascc3"
                     /gene_synonym="Helic1"
                     /EC_number="3.6.4.12"
                     /note="helicase, ATP binding 1"
                     /codon_start=1
                     /product="activating signal cointegrator 1 complex subunit
                     3"
                     /protein_id="NP_001263986.1"
                     /db_xref="GeneID:309887"
                     /db_xref="RGD:1307995"
                     /translation="MALPRLTGALRSFSNVTKQDNYNEEVADLKLKRSKLHEQALDFG
                     LSWKKIVKFLNEKLEKNKMQTINEDLKDILQAAKQIVGTDNGNEAIESGAAFLFMTFH
                     MTDSVGYTETKAIRQMFGPFPSSSATSACNATSRIISHFSQDDLTALVQATENQCNDR
                     VVFGRNLAFSFDMHDLDHFDELPVNGEAQKTISLDYKKFLNEQFQEPYTPELKPVEKS
                     NGSLLWCEVEKYLNATLKEMTEAPRVEDLCCTLYDMLASAKSGDELQDELFELLGPGG
                     LDLIEKLLQNRITIVDRFLNSSSDHKFQVLQDNCKKILGENAKPNYGCQVTIQSEQEK
                     QLMKQYRREEKRIARREKKAGEDGEVSGEGLLPFDPKELRLQREHALLNARSAPILGR
                     QRDTEVEKIRYPHVYDSQAAARETSAFIAGAKMILPEGIQRENTKLYEEVRIPYSEPM
                     PVGFEEKPVYIQDLDEVGQLAFKGMKRLNRIQSIVFDTAYNTNENMLICAPTGAGKTN
                     IAMLTVLHEIRQHFHQGVLKKNEFKIVYVAPMKALAAEMTNYFSKRLEPLGIVVKELT
                     GDMQLSKSEILRTQMLVTTPEKWDVVTRKSVGDVALSQIVKLLILDEVHLLHEDRGPV
                     LESIVARTLRQVESTQSMIRILGLSATLPNYLDVATFLHVNPYIGLFYFDGRFRPVPL
                     GQTFLGIKSANKMQQLNNMDEVCYESVLKQVKAGHQVMVFVHARNATVRTAMSLIERA
                     KNSGQISCFLPTQGPEYGHALKQVQKSRNKQVRELFSDGFSIHHAGMLRQDRNLVENL
                     FSNGHIKVLVCTATLAWGVNLPAHAVIIKGTQIYAAKRGSFVDLGILDVMQIFGRAGR
                     PQFDKFGEGIIITTHDKLSHYLSLLTQQNPIESQFLESLADNLNAEIALGTVTNVEEA
                     VKWMSYTYLYVRMRANPLAYGISHKAYQMDPTLRKHREQLLIEVGQKLDKARMIRFEE
                     RTGYFSSTDLGRTASHYYIKYNTIETFNELFDAHKTEGDIFAIVSKAEEFDQIKVREE
                     EIEELDALLNNFCELSAPGGVENSYGKINILLQTYISRGEMDSFSLISDSAYVAQNAA
                     RIVRALFEIALRKRWPTMTYRLLNLSKVIDKRLWGWASPLRQFSVLPPHILTRLEEKN
                     LTVDKLKDMRKDEIGHILHHVNIGLKVKQCVHQIPSVTMEASIQPITRTVLRVSLNIY
                     PDFSWNDQVHGTVGEPWWIWVEDPTNDHIYHSEYFLALKKQVINKEAQLLVFTIPIFE
                     PLPSQYYIRAVSDRWLGAEAVCIINFQHLILPERHPPHTELLDLQPLPVTALGCKAYE
                     ALYNFSHFNPVQTQIFHTLYHTDCNVLLGAPTGSGKTVAAELAIFRVFNKYPTSKAVY
                     IAPLKALVRERMDDWKIRIEEKLGKKVIELTGDVTPDMKSIAKADLIVTTPEKWDGVS
                     RSWQNRSYVQQVNILIIDEIHLLGEERGPVLEVIVSRTNFISSHTEKPVRIVGLSTAL
                     ANARDLADWLNIKQMGLFNFRPSVRPVPLEVHIQGFPGQHYCPRMASMNKPAFQAIRS
                     HSPAKPVLIFVSSRRQTRLTALELIAFLATEEDPKQWLNMDEQEMENIIATVRDSNLK
                     LTLAFGIGMHHAGLHERDRKTVEELFVNCKVQVLIATSTLAWGVNFPAHLVIIKGTEY
                     YDGKTRRYVDFPITDVLQMMGRAGRPQFDDQGKAVILVHDIKKDFYKKFLYEPFPVES
                     SLLGVLSDHLNAEIAGGTITSKQDALDYITWTYFFRRLIMNPSYYNLGDVSQDAINKF
                     LSHLIGQSLVELELSHCIEVGEDNRSIEPLTCGRIASYYYLKHKTVKMFKDRLKPECS
                     TEELLSILSDAEEYTDLPVRHNEDHTNNELAKCLPIELNPHSFDSPHTKAHLLLQAHL
                     SRAMLPCPDYDTDTKTVLDQALRVCQAMLDVAASQGWLVTTLNITHLIQMVIQGRWLK
                     DSSLLTIPNIEQHHLHLFRKWKPPVKGPHAKCRTSIECLPELIHACEGKEHVFSSMVE
                     KELQPAKTKQAWNFLSHLPVINVGISVKGSWDDSVEGHNELSISTLTADKRDENTWIK
                     LHADQQYVLQVSLQRVHFEFHKVKHESHAVTPRFPKLKDEGWFLILGEVDKRELVAVK
                     RVGFVRTHHEASISFFTPEAPGRYIFTLYLMSDCYLGLDQQYDIFLNVTKADISTQIN
                     TEVPDVSTDLA"
     exon            322..472
                     /gene="Ascc3"
                     /gene_synonym="Helic1"
                     /inference="alignment:Splign:2.1.0"
     exon            473..1032
                     /gene="Ascc3"
                     /gene_synonym="Helic1"
                     /inference="alignment:Splign:2.1.0"
     exon            1033..1153
                     /gene="Ascc3"
                     /gene_synonym="Helic1"
                     /inference="alignment:Splign:2.1.0"
     exon            1154..1361
                     /gene="Ascc3"
                     /gene_synonym="Helic1"
                     /inference="alignment:Splign:2.1.0"
     exon            1362..1503
                     /gene="Ascc3"
                     /gene_synonym="Helic1"
                     /inference="alignment:Splign:2.1.0"
     exon            1504..1629
                     /gene="Ascc3"
                     /gene_synonym="Helic1"
                     /inference="alignment:Splign:2.1.0"
     exon            1630..1830
                     /gene="Ascc3"
                     /gene_synonym="Helic1"
                     /inference="alignment:Splign:2.1.0"
     exon            1831..1971
                     /gene="Ascc3"
                     /gene_synonym="Helic1"
                     /inference="alignment:Splign:2.1.0"
     exon            1972..2136
                     /gene="Ascc3"
                     /gene_synonym="Helic1"
                     /inference="alignment:Splign:2.1.0"
     exon            2137..2313
                     /gene="Ascc3"
                     /gene_synonym="Helic1"
                     /inference="alignment:Splign:2.1.0"
     exon            2314..2385
                     /gene="Ascc3"
                     /gene_synonym="Helic1"
                     /inference="alignment:Splign:2.1.0"
     exon            2386..2520
                     /gene="Ascc3"
                     /gene_synonym="Helic1"
                     /inference="alignment:Splign:2.1.0"
     exon            2521..2712
                     /gene="Ascc3"
                     /gene_synonym="Helic1"
                     /inference="alignment:Splign:2.1.0"
     exon            2713..2937
                     /gene="Ascc3"
                     /gene_synonym="Helic1"
                     /inference="alignment:Splign:2.1.0"
     exon            2938..3057
                     /gene="Ascc3"
                     /gene_synonym="Helic1"
                     /inference="alignment:Splign:2.1.0"
     exon            3058..3222
                     /gene="Ascc3"
                     /gene_synonym="Helic1"
                     /inference="alignment:Splign:2.1.0"
     exon            3223..3309
                     /gene="Ascc3"
                     /gene_synonym="Helic1"
                     /inference="alignment:Splign:2.1.0"
     exon            3310..3486
                     /gene="Ascc3"
                     /gene_synonym="Helic1"
                     /inference="alignment:Splign:2.1.0"
     exon            3487..3712
                     /gene="Ascc3"
                     /gene_synonym="Helic1"
                     /inference="alignment:Splign:2.1.0"
     exon            3713..3867
                     /gene="Ascc3"
                     /gene_synonym="Helic1"
                     /inference="alignment:Splign:2.1.0"
     exon            3868..3966
                     /gene="Ascc3"
                     /gene_synonym="Helic1"
                     /inference="alignment:Splign:2.1.0"
     exon            3967..4135
                     /gene="Ascc3"
                     /gene_synonym="Helic1"
                     /inference="alignment:Splign:2.1.0"
     exon            4136..4356
                     /gene="Ascc3"
                     /gene_synonym="Helic1"
                     /inference="alignment:Splign:2.1.0"
     exon            4357..4442
                     /gene="Ascc3"
                     /gene_synonym="Helic1"
                     /inference="alignment:Splign:2.1.0"
     exon            4443..4609
                     /gene="Ascc3"
                     /gene_synonym="Helic1"
                     /inference="alignment:Splign:2.1.0"
     exon            4610..4755
                     /gene="Ascc3"
                     /gene_synonym="Helic1"
                     /inference="alignment:Splign:2.1.0"
     exon            4756..4876
                     /gene="Ascc3"
                     /gene_synonym="Helic1"
                     /inference="alignment:Splign:2.1.0"
     exon            4877..5019
                     /gene="Ascc3"
                     /gene_synonym="Helic1"
                     /inference="alignment:Splign:2.1.0"
     exon            5020..5157
                     /gene="Ascc3"
                     /gene_synonym="Helic1"
                     /inference="alignment:Splign:2.1.0"
     exon            5158..5278
                     /gene="Ascc3"
                     /gene_synonym="Helic1"
                     /inference="alignment:Splign:2.1.0"
     exon            5279..5411
                     /gene="Ascc3"
                     /gene_synonym="Helic1"
                     /inference="alignment:Splign:2.1.0"
     exon            5412..5537
                     /gene="Ascc3"
                     /gene_synonym="Helic1"
                     /inference="alignment:Splign:2.1.0"
     exon            5538..5649
                     /gene="Ascc3"
                     /gene_synonym="Helic1"
                     /inference="alignment:Splign:2.1.0"
     exon            5650..5784
                     /gene="Ascc3"
                     /gene_synonym="Helic1"
                     /inference="alignment:Splign:2.1.0"
     exon            5785..6009
                     /gene="Ascc3"
                     /gene_synonym="Helic1"
                     /inference="alignment:Splign:2.1.0"
     exon            6010..6161
                     /gene="Ascc3"
                     /gene_synonym="Helic1"
                     /inference="alignment:Splign:2.1.0"
     exon            6162..6309
                     /gene="Ascc3"
                     /gene_synonym="Helic1"
                     /inference="alignment:Splign:2.1.0"
     exon            6310..6519
                     /gene="Ascc3"
                     /gene_synonym="Helic1"
                     /inference="alignment:Splign:2.1.0"
     exon            6520..6695
                     /gene="Ascc3"
                     /gene_synonym="Helic1"
                     /inference="alignment:Splign:2.1.0"
     exon            6696..7446
                     /gene="Ascc3"
                     /gene_synonym="Helic1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gcggcgctga gtgggtttgt gggtcagtgc ttgccgggca gctctcgcgc gctaatcggt
       61 gacagcgtgc gaccctcgcc cgcccgcgtg tgctgcggag gaggtcgggg cgcagccctc
      121 cgccacgccg gagtgagaat tggaagcaaa tctccaggag gccggaggcg cgtgtggcgg
      181 cggggctgag ttcgagtttc ttacttctat ggatcactga ctgagtaata aatggcttta
      241 cctcgcctca caggagcctt gcgctccttt tcaaatgtca ccaagcaaga taattataat
      301 gaagaagtag ctgacttaaa gctgaagcga tccaaacttc atgaacaagc tttagatttc
      361 ggcctttcat ggaagaagat agtgaagttt ttgaatgaaa aactagaaaa gaataaaatg
      421 caaactataa atgaagactt aaaagatata ctacaagctg caaaacaaat cgttggaacg
      481 gataatggga atgaagcaat tgaaagtggg gctgcattcc tctttatgac gtttcacatg
      541 acagactctg ttggttacac ggagacaaag gctatcagac agatgtttgg accctttcca
      601 tcatcctctg ctacctcagc ttgtaatgcc actagtcgga ttatttcgca ttttagtcaa
      661 gatgatctca ctgctttagt ccaggcgaca gaaaaccaat gtaatgatag agtggtcttt
      721 ggtagaaact tagcattttc ctttgacatg catgatctgg accactttga tgaattacca
      781 gtaaatggtg aagcccagaa aactataagc ttagactaca agaagttcct gaatgaacag
      841 tttcaggaac cctacacccc agaactcaag cccgtggaaa aatcaaatgg ctccttattg
      901 tggtgtgaag tagagaagta cttaaacgca actctaaagg aaatgactga agcaccaaga
      961 gttgaagatc tgtgctgtac gttatatgac atgcttgctt ctgctaaaag cggggatgag
     1021 cttcaggatg agctttttga attgctggga cctggaggac ttgatttgat tgagaagcta
     1081 ctccagaaca gaattacaat cgtagatcga tttcttaatt cctcaagtga tcataagttc
     1141 caagttcttc aagataattg taaaaaaatt ttaggagaga atgcgaagcc taattatggt
     1201 tgtcaagtca cgattcagtc cgaacaagaa aagcagttaa tgaaacagta tcggcgtgag
     1261 gaaaaaagaa ttgccaggag agaaaagaag gctggggaag atggggaagt ttctggagaa
     1321 ggacttttgc cctttgatcc taaggaactc cgattacaga gagaacatgc gcttctgaat
     1381 gctagaagtg ctccaatttt gggaaggcag agagacacgg aggttgagaa aattcgttat
     1441 cctcatgttt atgattccca ggctgcagcc cgagaaacat cagcatttat agctggggcc
     1501 aagatgattt tgccagaagg catccagaga gagaatacca agctgtatga agaagtaagg
     1561 atcccctata gtgaaccaat gcccgttggg tttgaggaga aaccagttta tatccaggat
     1621 ttagatgagg tgggacagtt ggcttttaaa ggaatgaaga gactcaatag aatccagtct
     1681 atagtatttg acacagccta caacaccaac gaaaacatgc tcatctgtgc ccctactgga
     1741 gctgggaaga ccaatattgc aatgctcact gtcttacatg aaatccgcca acactttcac
     1801 caaggtgttc ttaaaaagaa tgagtttaag attgtgtatg ttgctccaat gaaagccttg
     1861 gcagctgaaa tgacgaatta cttcagcaaa cgtctagagc cactgggcat tgttgtgaaa
     1921 gaattgactg gagatatgca gttgtcaaaa agtgaaattc tacgaactca gatgcttgtg
     1981 accacaccag aaaaatggga tgtagtaaca agaaagagtg ttggggatgt tgctctttcc
     2041 caaattgtaa aactcctgat tctcgatgag gttcacttgc tgcatgaaga cagaggccca
     2101 gtgctagaaa gcatagttgc gaggacctta cggcaggttg aatccacaca gagtatgata
     2161 agaatccttg gcttatctgc aaccttgccc aactacctgg atgttgctac atttttacat
     2221 gttaacccct acattggtct tttctacttt gatggccgtt ttcgacctgt acctctggga
     2281 cagacatttt tagggattaa aagtgcaaat aagatgcagc agttaaataa catggatgaa
     2341 gtgtgctacg aaagcgttct gaagcaagta aaggctggac accaggtgat ggtatttgta
     2401 catgctcgaa atgccactgt aaggacagct atgtctctaa tagagagagc aaaaaacagt
     2461 ggccagatct cctgttttct ccccacccaa ggaccagagt atgggcatgc attgaaacag
     2521 gtacaaaagt caagaaataa gcaagtgcga gagttattct cagatggctt tagcattcat
     2581 catgccggga tgcttcggca agacagaaat ttggttgaaa atttgttctc aaatgggcac
     2641 atcaaagtcc tggtttgcac agccacccta gcctggggtg tcaatctccc tgcacatgcc
     2701 gtcattatta agggaacaca aatctatgct gccaaaagag gctcctttgt tgaccttgga
     2761 attttagatg tcatgcagat atttggccga gccggacgac cgcaatttga caaatttggg
     2821 gaaggaatca ttataaccac acatgataaa ctcagccatt acctcagttt gctcactcaa
     2881 caaaacccga ttgagagtca gtttctggaa agtcttgcag ataacctaaa tgcagagatt
     2941 gcactaggaa cagtcaccaa tgtggaagag gcggtgaagt ggatgagtta cacgtacctc
     3001 tacgtgcgga tgagagcaaa cccactcgcc tacggcatca gtcacaaagc ataccagatg
     3061 gacccaacgt taagaaagca ccgagaacag ctcctcattg aagttggaca aaagctggat
     3121 aaagctagga tgattcgctt tgaagaacga actggctatt tttcttccac tgatttgggt
     3181 agaactgcca gccactacta tattaaatac aacaccattg agacattcaa tgaactcttt
     3241 gatgcacaca aaacagaagg tgatatcttt gctattgtct ccaaagctga agaatttgat
     3301 caaattaagg tcagagaaga agaaatagaa gaattagatg ccttgttaaa caatttctgt
     3361 gaactctcag ctccaggagg tgtggaaaat agttatggga aaataaacat cctacttcag
     3421 acctacatca gccgaggaga gatggacagt ttctccctca tatcagattc cgcatatgtt
     3481 gcccagaatg cagctagaat tgtccgtgct ctctttgaaa ttgcactgag gaaacgttgg
     3541 cctaccatga cctacaggct tttgaatctt agtaaagtca ttgacaagag actctggggt
     3601 tgggctagcc ctttgagaca attttctgtg ttaccaccac acatcctaac aagattagaa
     3661 gaaaaaaacc ttacagtgga taaactcaaa gacatgagaa aagatgaaat aggtcacatt
     3721 ttgcatcatg tgaatattgg actgaaggtc aaacagtgtg ttcatcagat tccttctgtt
     3781 acaatggaag cttccattca gcccatcaca cggactgtcc tccgagtctc actgaacatc
     3841 taccctgatt tctcttggaa tgatcaggtc catggcacag taggggaacc gtggtggatc
     3901 tgggtagaag atcctacaaa cgaccatatt tatcactcgg agtactttct agctcttaaa
     3961 aaacaggtta ttaataaaga agctcaactt ctggtattta caatccctat ttttgagcct
     4021 ttgccctctc agtactacat tcgagcagta tctgatagat ggctaggagc tgaagctgtt
     4081 tgcattatca actttcaaca tctgattcta ccagagagac atcctcccca tacagaatta
     4141 ttggaccttc agcctttgcc agtcacagcc ttggggtgca aagcatatga agctctgtat
     4201 aacttcagcc acttcaaccc ggtgcagaca cagatattcc acacgctgta tcacactgac
     4261 tgtaacgtcc tacttggagc ccccacgggg tcaggaaaga cagttgcagc tgaactcgcc
     4321 attttcagag tcttcaacaa gtatcccact tccaaggcag tatatattgc acccctcaaa
     4381 gctctagtac gtgaaagaat ggatgattgg aaaattagaa tagaagaaaa acttggtaaa
     4441 aaagttattg aactgactgg ggatgtgact ccagacatga aatccattgc taaggctgac
     4501 cttatcgtca ctacaccaga aaagtgggat ggcgtcagtc gaagctggca gaacaggagc
     4561 tacgttcagc aggtcaacat tctcatcata gatgagatcc acctgctagg tgaggagaga
     4621 ggtccagttc tagaagtcat tgtatctcga acaaacttta tctcatcgca cacagagaag
     4681 cctgttagaa tagtcggact gtccactgcc ttagccaatg ctagagacct tgctgactgg
     4741 ctcaacatta agcagatggg tttgtttaac ttccgacctt ctgtgcgccc tgttccactg
     4801 gaagttcaca ttcaaggttt cccaggacaa cattactgcc cacgcatggc tagtatgaac
     4861 aagcctgcat tccaggcaat tagaagtcat tctccagcca aacctgtttt gatatttgtc
     4921 tcctcaagac gtcaaacacg gcttacggct ttagagttga tagctttcct ggccactgaa
     4981 gaagacccaa agcagtggtt aaacatggac gagcaagaga tggagaacat cattgcaaca
     5041 gtgcgagatt ccaaccttaa gctgactcta gcttttggaa taggaatgca tcatgctgga
     5101 ctacatgaaa gagaccgaaa aactgtggaa gagctgtttg tgaactgtaa agtgcaggtt
     5161 ctcattgcga caagcacgtt agcatggggt gtaaactttc cagcacactt agtcattatt
     5221 aagggaactg aatactacga tggaaagaca agacgctatg tggatttccc catcacagat
     5281 gtactgcaga tgatggggcg agctgggaga cctcagtttg atgaccaggg caaagctgta
     5341 attctagttc atgatataaa aaaggatttt tataaaaagt ttctttatga acctttccca
     5401 gtggaatcga gcttattagg agtgttgtct gaccacttaa atgcagagat tgcgggaggt
     5461 acaataacat caaagcaaga tgccttggat tatatcactt ggacttactt tttccgacgt
     5521 cttatcatga atcccagcta ctacaacttg ggggacgtca gccaggacgc cataaacaag
     5581 ttcctgtcac atctgattgg gcaatctctg gttgagttgg agctttccca ctgcattgaa
     5641 gttggagagg acaatcgcag cattgaacca ctgacatgtg gccgaattgc ctcctattac
     5701 tatctgaagc acaagacagt caaaatgttc aaggaccgtt taaagcctga gtgcagcact
     5761 gaagaattgc tgtcaattct aagtgatgcg gaagaataca cagacttgcc agtaagacac
     5821 aatgaggacc atacgaataa tgaactggcc aaatgtcttc ccattgaatt aaatcctcat
     5881 tcatttgaca gccctcacac caaagcccat ctcttgcttc aagcacatct cagccgagcc
     5941 atgctgccct gcccagacta tgatactgat accaaaacag tcttagatca agctctcaga
     6001 gtatgccagg caatgctgga tgtggctgca agccaaggat ggctagtgac taccctgaat
     6061 atcacccacc tgattcagat ggtgatccaa ggccgatggc taaaggactc gtctcttctt
     6121 accataccaa acatagaaca gcaccatctt caccttttca ggaagtggaa accacctgta
     6181 aagggcccac atgctaagtg ccgaacatcc attgagtgcc ttcctgagct gatccatgcc
     6241 tgtgaaggga aggagcatgt gttcagctcc atggtagaga aggagttaca gcctgcgaaa
     6301 acaaagcagg catggaattt cttatctcac ttgcccgtga taaatgttgg cataagtgtt
     6361 aaaggctcct gggatgactc agttgaagga cataatgaac tctccatctc aactctgaca
     6421 gcagacaaac gggatgaaaa cacatggatc aagttgcatg ctgatcagca gtatgtgctt
     6481 caagtcagcc tacagagagt ccattttgag ttccacaagg taaaacatga gagtcacgca
     6541 gttactcctc gatttccaaa attaaaagat gaagggtggt ttttgatatt aggagaagtg
     6601 gataagagag agctggtggc tgtaaaacgc gtaggatttg ttcgaactca tcacgaggct
     6661 tccatctctt tctttactcc ggaagcacct ggaagatata tctttaccct gtatctcatg
     6721 agtgactgtt acctcggcct agaccagcag tatgacatct ttctcaatgt cacaaaagca
     6781 gacatctcca cccagatcaa cacagaagtc cctgatgtct caactgactt ggcataatat
     6841 tgtgacccaa acaggccatt gaaccaagga gctgagtctc ggctgctcag tcatgtggac
     6901 aagctgaatt atttggtgtc tgccttggca aaatcaactt caaacctaaa aacaactagg
     6961 aaattgacag cagccacagt gttgattcca gctacattag cctggactgc tgccttttgt
     7021 aacagatttg tgggtttctt tacatgtaag ataagtaagc tctagtatca tttttaagtc
     7081 gtgtacattg gagtgatagt tatggattat caaactttgc atctcatgat gtactgttta
     7141 catgaatacc agctactctt tttttctaaa gaaaattaca ttgtgatgtg acgggttaaa
     7201 agtttaagca acttaaaata tataattcta tgacgtgata caaagttgat cttattagca
     7261 aaattcatac tttggtttga tcacatataa aaatagcttc acagatttct tataaatcat
     7321 agtaatatat gatatgaaat tatattgcag agatcaatga cttttcaaag atcatacact
     7381 gatcttggaa aatgtgaaca ctgtaactgg tggaaataaa atatatagag tgctccttcc
     7441 agacaa
//
