LOCUS       NM_001011984            2512 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus ankyrin repeat and SOCS box-containing 2 (Asb2),
            mRNA.
ACCESSION   NM_001011984 XM_216768
VERSION     NM_001011984.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2512)
  AUTHORS   Rajan,S., Chu Pham Dang,H., Djambazian,H., Zuzan,H., Fedyshyn,Y.,
            Ketela,T., Moffat,J., Hudson,T.J. and Sladek,R.
  TITLE     Analysis of early C2C12 myogenesis identifies stably and
            differentially expressed transcriptional regulators whose
            knock-down inhibits myoblast differentiation
  JOURNAL   Physiol Genomics 44 (2), 183-197 (2012)
   PUBMED   22147266
REFERENCE   2  (bases 1 to 2512)
  AUTHORS   Bello,N.F., Lamsoul,I., Heuze,M.L., Metais,A., Moreaux,G.,
            Calderwood,D.A., Duprez,D., Moog-Lutz,C. and Lutz,P.G.
  TITLE     The E3 ubiquitin ligase specificity subunit ASB2beta is a novel
            regulator of muscle differentiation that targets filamin B to
            proteasomal degradation
  JOURNAL   Cell Death Differ 16 (6), 921-932 (2009)
   PUBMED   19300455
REFERENCE   3  (bases 1 to 2512)
  AUTHORS   Kohroki,J., Nishiyama,T., Nakamura,T. and Masuho,Y.
  TITLE     ASB proteins interact with Cullin5 and Rbx2 to form E3 ubiquitin
            ligase complexes
  JOURNAL   FEBS Lett 579 (30), 6796-6802 (2005)
   PUBMED   16325183
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC085882.1.
            
            On Feb 11, 2005 this sequence version replaced XM_216768.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC085882.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN06621351, SAMN11044071
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..2512
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="6"
                     /map="6q32"
     gene            1..2512
                     /gene="Asb2"
                     /note="ankyrin repeat and SOCS box-containing 2"
                     /db_xref="GeneID:299266"
                     /db_xref="RGD:1306414"
     exon            1..107
                     /gene="Asb2"
                     /inference="alignment:Splign:2.1.0"
     exon            108..384
                     /gene="Asb2"
                     /inference="alignment:Splign:2.1.0"
     CDS             179..2083
                     /gene="Asb2"
                     /note="ASB-2; ankyrin repeat and SOCS box-containing
                     protein 2; ankyrin repeat and SOCS box protein 2-like"
                     /codon_start=1
                     /product="ankyrin repeat and SOCS box protein 2"
                     /protein_id="NP_001011984.1"
                     /db_xref="GeneID:299266"
                     /db_xref="RGD:1306414"
                     /translation="MSTEISTRGRQRAIGHEEYSLYSSLSEEELVQMAIEQSLADKTR
                     GPTPAETSVSSQTNHQPGHIHPWTRSSSPPESPPARAPLGLFQGVMQKYSSNLFKTSQ
                     MAAMDPVLKAIKEGDEEALKAMIQDGKNLAEPNKEGWLPLHEAAYYGKLGCLKVLQRA
                     YPGTIDQRTLQEETALYLATCREHLDCLLSLLQAGAEPDISNKSRETPLYKACERKNA
                     EAVRILVQYNADANHRCNRGWTALHESVSRNDLEVMEILVSGGAKVEAKNVYSITPLF
                     VAAQSGQLEALRFLAKHGADINTQASDSASALYEACKNEHEDVVEFLLSQGADANKAN
                     KDGLLPLHVASKKGNYRIVQMLLPVTSRTRVRRSGISPLHLAAERNHDAVLEALLAAR
                     FDVNTPLAPERARLYEDRRTSALYFAVVNNNVYATELLLLAGADPNRDVISPLLVAIR
                     HGCLRTMQLLLDHGANIDAYIATHPTAFPATIMFAMKCLSLLKFLMDLGCDGEPCFSC
                     LYGNGPHPPAPRSGRFNDAPVDDKAPSVVQFCEFLSAPEVSRWAGPIIDVLLDYVGNV
                     QLCSRLKEHIDSFEDWAVIKEKAEPPRPLAHLCRLRVRKAIGKYRIKLLDTLPLPGRL
                     IRYLKYENTQ"
     exon            385..489
                     /gene="Asb2"
                     /inference="alignment:Splign:2.1.0"
     exon            490..656
                     /gene="Asb2"
                     /inference="alignment:Splign:2.1.0"
     exon            657..812
                     /gene="Asb2"
                     /inference="alignment:Splign:2.1.0"
     exon            813..1058
                     /gene="Asb2"
                     /inference="alignment:Splign:2.1.0"
     exon            1059..1230
                     /gene="Asb2"
                     /inference="alignment:Splign:2.1.0"
     exon            1231..1792
                     /gene="Asb2"
                     /inference="alignment:Splign:2.1.0"
     exon            1793..1946
                     /gene="Asb2"
                     /inference="alignment:Splign:2.1.0"
     exon            1947..2485
                     /gene="Asb2"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ctcagggcca gcacaggagg caaactcaga gagcatgttc tgaagtcaga cagtcaagag
       61 aatctctttg ttgcctagac ctgtgcccct gccacagagc ctcgcaggga ctggtcacct
      121 gccgtgtgct ggctgctgct gagtcactct tctggaagct ggggcagagg tggccaagat
      181 gtcgactgag atctccactc ggggcagaca gcgtgccatt gggcatgagg aatacagcct
      241 gtacagcagc ttgagtgagg aggagctggt ccagatggcc attgagcaga gcctggcaga
      301 caagactcgg ggcccaaccc ctgctgagac ctctgtgtcc tctcagacca accaccagcc
      361 aggccatatc cacccatgga ccaggtcctc ctctcctccc gagagcccac cggcccgagc
      421 acccctgggc ctgttccaag gggtcatgca gaagtatagc agcaacctgt tcaagacctc
      481 ccagatggcg gctatggacc ccgtgctgaa ggccatcaag gaaggggatg aagaagcctt
      541 gaaggccatg atccaggatg ggaagaatct tgcagagccc aacaaggagg gctggctgcc
      601 gcttcacgag gctgcctact atggcaagct gggctgcctg aaagtcctgc aacgagctta
      661 cccagggacc attgaccagc gtacactgca ggaagagaca gcactatacc tggctacgtg
      721 cagagaacac ctggactgcc tcctgtccct gctccaggcg ggggcagagc ctgacatctc
      781 taacaaatcc agggagaccc cactttacaa agcctgtgag cgcaagaacg cggaggccgt
      841 gaggatattg gtgcaataca atgcagacgc caaccaccgc tgcaacaggg gctggacggc
      901 cctgcatgag tctgtctcac gcaatgacct ggaggtcatg gagatcctag tgagcggcgg
      961 ggccaaggtg gaagccaaga acgtctacag cattaccccc ttgtttgtgg ctgcccagag
     1021 cgggcagctg gaggccctga ggttcctggc caagcatggt gcagacatca acacgcaggc
     1081 cagcgacagc gcgtccgccc tctacgaggc ctgcaagaac gagcatgaag acgtggtgga
     1141 gtttcttctc tcgcagggcg ccgacgctaa caaagccaac aaggacggct tgcttccact
     1201 gcacgttgcc tccaagaagg gcaattatag aatagtgcag atgctgttgc ctgtgaccag
     1261 ccgcacgcgc gtgcgccgta gcggcatcag cccgctgcac ctggcggccg agcgcaacca
     1321 cgacgcggtg ctggaggcgc tgctggccgc gcgcttcgac gtgaacacgc ctctggctcc
     1381 cgagcgcgcg cgcctctacg aggaccgccg cacttcagcg ctctacttcg ccgtggtcaa
     1441 caacaatgtg tacgccacgg agttgttgct gctggcgggc gccgacccca accgcgacgt
     1501 catcagcccc ctgctcgtgg ccatccgcca cggctgcctg cgcaccatgc agctgctgtt
     1561 ggaccatggt gcaaacatcg acgcctacat cgccactcac cccactgcct tcccggccac
     1621 catcatgttt gccatgaagt gcctttcgtt actcaagttc ctcatggacc tcggttgcga
     1681 tggcgagccc tgcttttcct gcctgtatgg caacgggcca cacccacctg ccccacgatc
     1741 cggccgcttc aacgacgcgc ccgtggacga caaggcaccc agcgtggtgc agttctgtga
     1801 gttcctgtcg gccccggaag tgagccgctg ggcgggaccc atcatcgatg tccttctgga
     1861 ctatgtcggc aacgtgcagc tgtgctcccg gctgaaggag cacatcgaca gctttgagga
     1921 ctgggctgtc atcaaggaga aggcagaacc tccaagacct ctggctcacc tctgccggct
     1981 gcgggttcgg aaggccatag ggaaataccg gataaaactc ctggacacac tgcccctccc
     2041 gggcaggcta atcagatacc tgaaatacga gaatacacag taaccagcct ggagagaagg
     2101 tgtggccttc agactgtttc ctcgacaccc caggcggcct gcctccaggc cccgctgggg
     2161 tcagaacaag tgtggtcctc ctgggtctct actagagctt cgctggaagt aagagccgat
     2221 gtgcggagtg gagatggcgc ctcagctttc aaactgttct gtggatggca gacctgctct
     2281 cctggccgta gccagggacc gtcaacctgg ggtcagggaa gagctgctct gggcaaggtg
     2341 gcccaggcag gaatcttggc ctcacgctgg agaacttcta ggaatgagtt cacctaggga
     2401 tcctcactgg actctgagct ttcaggctgg gagggggagc cccgcctgag tacatcattg
     2461 agtacaataa acattgtata cggaaaaaaa aaaaaaaaaa aaaaaaaaaa aa
//
