LOCUS       NM_001131013            3804 bp    mRNA    linear   ROD 31-MAR-2024
DEFINITION  Rattus norvegicus ARVCF, delta catenin family member (Arvcf), mRNA.
ACCESSION   NM_001131013
VERSION     NM_001131013.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 3804)
  AUTHORS   Kausalya,P.J., Phua,D.C. and Hunziker,W.
  TITLE     Association of ARVCF with zonula occludens (ZO)-1 and ZO-2: binding
            to PDZ-domain proteins and cell-cell adhesion regulate plasma
            membrane and nuclear localization of ARVCF
  JOURNAL   Mol Biol Cell 15 (12), 5503-5515 (2004)
   PUBMED   15456900
REFERENCE   2  (bases 1 to 3804)
  AUTHORS   Laura,R.P., Witt,A.S., Held,H.A., Gerstner,R., Deshayes,K.,
            Koehler,M.F., Kosik,K.S., Sidhu,S.S. and Lasky,L.A.
  TITLE     The Erbin PDZ domain binds with high affinity and specificity to
            the carboxyl termini of delta-catenin and ARVCF
  JOURNAL   J Biol Chem 277 (15), 12906-12914 (2002)
   PUBMED   11821434
REFERENCE   3  (bases 1 to 3804)
  AUTHORS   Waibler,Z., Schafer,A. and Starzinski-Powitz,A.
  TITLE     mARVCF cellular localisation and binding to cadherins is influenced
            by the cellular context but not by alternative splicing
  JOURNAL   J Cell Sci 114 (Pt 21), 3873-3884 (2001)
   PUBMED   11719554
REFERENCE   4  (bases 1 to 3804)
  AUTHORS   Kaufmann,U., Zuppinger,C., Waibler,Z., Rudiger,M., Urbich,C.,
            Martin,B., Jockusch,B.M., Eppenberger,H. and Starzinski-Powitz,A.
  TITLE     The armadillo repeat region targets ARVCF to cadherin-based
            cellular junctions
  JOURNAL   J Cell Sci 113 (Pt 22), 4121-4135 (2000)
   PUBMED   11058098
REFERENCE   5  (bases 1 to 3804)
  AUTHORS   Sirotkin,H., O'Donnell,H., DasGupta,R., Halford,S., St Jore,B.,
            Puech,A., Parimoo,S., Morrow,B., Skoultchi,A., Weissman,S.M.,
            Scambler,P. and Kucherlapati,R.
  TITLE     Identification of a new human catenin gene family member (ARVCF)
            from the region deleted in velo-cardio-facial syndrome
  JOURNAL   Genomics 41 (1), 75-83 (1997)
   PUBMED   9126485
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000011.1 and BC168253.1.
            
            On Mar 11, 2021 this sequence version replaced NM_001131013.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC168253.1, SRR26643287.27433.1
                                           [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA5760386,
                                           SAMEA5760400 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-27                JAXUCZ010000011.1  96150118-96150144   c
            28-3804             BC168253.1         1-3777
FEATURES             Location/Qualifiers
     source          1..3804
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="11"
                     /map="11q23"
     gene            1..3804
                     /gene="Arvcf"
                     /note="ARVCF, delta catenin family member"
                     /db_xref="GeneID:303798"
                     /db_xref="RGD:1306655"
     exon            1..227
                     /gene="Arvcf"
                     /inference="alignment:Splign:2.1.0"
     exon            228..279
                     /gene="Arvcf"
                     /inference="alignment:Splign:2.1.0"
     exon            280..510
                     /gene="Arvcf"
                     /inference="alignment:Splign:2.1.0"
     CDS             298..3219
                     /gene="Arvcf"
                     /note="armadillo repeat protein deleted in
                     velo-cardio-facial syndrome; armadillo repeat gene deleted
                     in velo-cardio-facial syndrome; armadillo repeat protein
                     deleted in velo-cardio-facial syndrome homolog"
                     /codon_start=1
                     /product="splicing regulator ARVCF"
                     /protein_id="NP_001124485.1"
                     /db_xref="GeneID:303798"
                     /db_xref="RGD:1306655"
                     /translation="MEDCNVHSAASILASVKEQEARFERLTRALEQERRHVALQLERA
                     QQPGMSSGGMVGSGQPLPMAWQQLVLQEQSPGSQASLATMPEAPEVLEETVTVEEDPG
                     TPTSHVSIVTSEDGTTRRTETKVTKTVKTVTTRTVRQVPLGPDGLPLLDGGPPLGSFA
                     DGPLDRHYVLRGGGPAATLSRAYLSSGGGFPDGPEPRDIPSYGSLSRGLGVRPPRTGL
                     LGPGPGDGCFTLPGRREAFPMGSESGPPSGRSLPEHFQAEPYGLEDDTRSLAADDEGG
                     PDLEPDYSTATRRRPEYGRGLRARALEDTADDTGELVEERPPFPAATAPLAQPERGSL
                     GSLDRVVRRSPSVDSTRKEPRWRDPELPEVLAMLRHPVDPVKANAAAYLQHLCFENEG
                     IKRRVRQLRGLPLLVALLDHPRAEVRRRACGALRNLSYGRDADNKAAIRDCGGVPALV
                     RLLRAARDNEVRELVTGTLWNLSSYEPLKMVIIDHGLQTLTHEVIVPHSGWEREPNED
                     SKPRDAEWTTVFKNTSGCLRNVSSDGAEARRRLRECEGLVDALLHALQSAVGRKDTDN
                     KSVENCVCIMRNLSYHVHKEVPGADRYQEVEPGIPGSAATSQRRRKDDASCFGGKKAK
                     GKKDAEADRNFDTLDLPKRTEAAKGFELLYQPEVVRLYLSLLTESRNFNTLEAAAGAL
                     QNLSAGNWMWATYIRATVRKERGLPVLVELLQSETDKVVRAVAIALRNLSLDQRNKDL
                     IGSYAMTELVRNVRNAQAPAHPSAHLEEDTVVAVLNTIHEIVSDSLDNARSLLQARGV
                     PALVALVASSQSVREAKAASHVLQTVWSYKELRGALQRDGWTKAHFQSASTAKGPKGT
                     PNSGGFDDSTLPLVDKNLDGEKSTTRDVIPMDTLGPDGYSTVDRRERRTLGSDSIGDS
                     SEKELLKGPGPAVCSSDHMEVIGRGPSGTDPVLGPGAPPFCVGLAKPLVYLALPSSLL
                     S"
     exon            511..669
                     /gene="Arvcf"
                     /inference="alignment:Splign:2.1.0"
     exon            670..1196
                     /gene="Arvcf"
                     /inference="alignment:Splign:2.1.0"
     exon            1197..1696
                     /gene="Arvcf"
                     /inference="alignment:Splign:2.1.0"
     exon            1697..1880
                     /gene="Arvcf"
                     /inference="alignment:Splign:2.1.0"
     exon            1881..1998
                     /gene="Arvcf"
                     /inference="alignment:Splign:2.1.0"
     exon            1999..2170
                     /gene="Arvcf"
                     /inference="alignment:Splign:2.1.0"
     exon            2171..2242
                     /gene="Arvcf"
                     /inference="alignment:Splign:2.1.0"
     exon            2243..2370
                     /gene="Arvcf"
                     /inference="alignment:Splign:2.1.0"
     exon            2371..2521
                     /gene="Arvcf"
                     /inference="alignment:Splign:2.1.0"
     exon            2522..2720
                     /gene="Arvcf"
                     /inference="alignment:Splign:2.1.0"
     exon            2721..2832
                     /gene="Arvcf"
                     /inference="alignment:Splign:2.1.0"
     exon            2833..2920
                     /gene="Arvcf"
                     /inference="alignment:Splign:2.1.0"
     exon            2921..2974
                     /gene="Arvcf"
                     /inference="alignment:Splign:2.1.0"
     exon            2975..3060
                     /gene="Arvcf"
                     /inference="alignment:Splign:2.1.0"
     exon            3061..3804
                     /gene="Arvcf"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gctttgcgca cgggccgcgg gaggggtggg agggctagcc tgctggctgc ttggggtagg
       61 ggaggaggag ggttttcccc aacccccgca cccgcataag ttgtggcccc gggagccgca
      121 ttcggtgcag gacgctggag aggccgctcc ccgcgcgccg ggagacctgg ggacgccagt
      181 cttgggggcg gaggccgcgc tgcggagccg cccacgccgc gcgccaggaa cagagtccac
      241 aagatgggca ttaggacatg ctgagacccc ctgaaatagg ctgctggcac cctggtcatg
      301 gaggactgca atgtgcattc ggccgccagc attctggcct cggtgaaaga acaggaggcc
      361 cgattcgagc ggctgacacg ggcactagag caagaacggc gccacgtcgc cctgcagctg
      421 gagcgtgccc agcagcctgg catgagcagt ggtggtatgg tgggcagtgg gcagcccctg
      481 ccaatggcct ggcagcagct ggttctgcag gaacagagcc cgggtagcca ggcatcgctg
      541 gccacgatgc cagaggcacc tgaggtgctg gaggagacag tgactgtgga ggaagaccct
      601 ggcaccccca cctctcatgt atccattgtc acatcagaag acggtacaac ccggcggact
      661 gagactaagg tcactaagac agtcaagact gtgaccacaa ggacagtccg ccaggtgcct
      721 ttgggtccag atggactccc cttgctagat ggcggccctc ctcttggctc ttttgctgat
      781 gggcccctgg accggcacta cgtcctgcgt ggtggtggcc cagcagccac actctcccga
      841 gcctacctca gcagtggagg tggctttccc gatggccccg agccccgtga tattccaagc
      901 tacggcagct tgtcccgagg gcttggggta cggccaccac gtactggcct cttgggcccg
      961 ggacctggtg atggctgttt cacactccct ggccgccgag aagccttccc catgggctca
     1021 gaatctggac caccaagtgg ccgctctctg cctgagcatt tccaagcaga gccatatggc
     1081 ctggaggatg acactcggag cctggctgca gatgatgagg gcggccccga cctggagcct
     1141 gactacagca cagccacacg gagaagacct gagtacgggc ggggcctccg tgccagggcc
     1201 ttggaagaca ccgcagatga cactggtgag ctggtagaag agcggccccc gttcccagcc
     1261 gcaacagccc ctctagccca gcctgagagg ggcagcctgg gcagcttgga ccgagtagtg
     1321 cggcgctcac cctcagtaga cagcacccgc aaggagccgc gctggaggga ccctgagctg
     1381 cccgaggtgc tggccatgct gcggcacccc gtggaccctg tgaaagccaa cgccgcagcc
     1441 tacctgcagc acctctgctt tgagaacgag ggcatcaagc gtcgggtgcg gcagctgcgt
     1501 gggctgcccc tactcgtggc gttactagat caccctcggg ctgaggtgcg ccgccgggcc
     1561 tgcggggcac tgcgcaacct ctcctatggc cgcgatgccg acaacaaggc tgccatccgg
     1621 gactgcgggg gcgtgccagc cctggtgcgc ctgctgcggg ctgcccgtga caatgaggtc
     1681 cgtgagctgg tcactggcac actctggaac ctgtcatcct acgagcccct gaagatggtc
     1741 atcattgacc acggcttaca gactctgacc catgaggtca tcgtgcccca ttctggctgg
     1801 gagcgagagc ctaatgaaga ctcgaagccc cgggatgccg agtggacgac agtctttaag
     1861 aacacatcag gctgcctgag gaacgtgagc tcagatggtg cagaggcccg gcggcgactt
     1921 cgtgagtgcg aagggctggt ggacgctctc ttacatgccc tgcagtcagc tgtgggcagg
     1981 aaagacacag ataataagtc agtagagaac tgtgtgtgca tcatgcggaa cctgtcctac
     2041 cacgtgcaca aggaagttcc aggggctgac aggtaccagg aggtggagcc tgggatcccg
     2101 ggcagtgctg caacctccca gcgtcggagg aaggatgacg ccagctgctt tggtggcaag
     2161 aaagcgaaag ggaagaagga tgcagaggcc gaccggaact ttgacacatt ggacctgccc
     2221 aaacgtactg aagctgcgaa aggcttcgag ctgctgtacc agccggaggt ggtgcgactt
     2281 tacctgtcac tccttacgga gagccggaac ttcaacaccc tagaagctgc agcgggtgcc
     2341 ctgcagaacc tcagtgctgg caactggatg tgggccacgt atatccgtgc cacagtgcgc
     2401 aaggaacgtg ggctgccagt gctggtggaa ctgctacagt ctgagaccga caaggtggtg
     2461 cgtgctgtgg ccatcgcact gcgcaacctg tcactagacc agcggaacaa agacctcatc
     2521 gggagctacg ccatgacaga gctggttcgg aatgttcgca acgcacaggc tcctgcccac
     2581 cccagtgccc acctggagga ggatacagtg gtagctgtgc tcaacaccat ccatgagatt
     2641 gtgtccgaca gcctggacaa tgctcgctcc ctcctgcagg cccgtggtgt gcctgcactg
     2701 gtggcacttg tggcctccag ccagtcagtg cgggaggcca aggcagcatc acacgtgcta
     2761 cagactgtgt ggagctacaa ggagctgcgt ggagccctac agagggacgg ctggacgaaa
     2821 gcacacttcc agtctgctag cactgccaaa ggacccaaag ggacaccaaa ttctggaggc
     2881 tttgatgaca gcacactgcc actggtagac aagaaccttg atggggagaa gtcaactact
     2941 cgggatgtga tccccatgga tacccttggt ccagatggct acagcacagt tgaccggagg
     3001 gagaggagga cactgggcag cgactccata ggcgactcct ctgagaagga actactgaaa
     3061 ggccctggcc cagctgtttg ttcttcggat cacatggagg taattggaag agggccgtct
     3121 ggaacagacc cagtcttggg gccaggagcc ccacccttct gtgttgggtt ggccaagcct
     3181 cttgtctacc ttgccctgcc ctcctctcta ctctcctgat ctaactctcc aggtccgagt
     3241 tagctattta ctgacatggt gctgtgtggt aggagaggag gttgggggga ggtcccctgc
     3301 acagccacag aggagcaaat accagcctgg agtggaggcc ttggagcagg caaagggaca
     3361 agtagggggt cttggaaaag aacttgggct cccaagggtg gctggaggac taccctgcat
     3421 gccggctggc cacagtgagg gctgctccaa gagtccagac agggaagttt aggaggcggc
     3481 tggtttgggg gtgggagcaa gctgtgcttg tccccggcgc ccccgtcctt ggattcccgg
     3541 aacaccttcc atctgcagca cacttctcct aagctgcctg tggctggggc ctccctagct
     3601 gttgcatctg cctagaacct caagtaacct cggggcctga ctgccggcag cagcgggggg
     3661 aactgctgtt cagtgcctgc tgtttgtgac ttaaaaatga agaaaactga caaaatgcat
     3721 taaaaacgaa accaaaatga gactgtatca acaaacattg aaatttttct aagaaaattt
     3781 aaagattaaa aaagcagcaa agaa
//
