LOCUS       NM_001047917            3181 bp    mRNA    linear   ROD 01-APR-2024
DEFINITION  Rattus norvegicus arylsulfatase family, member K (Arsk), mRNA.
ACCESSION   NM_001047917 XM_001059083 XM_345131
VERSION     NM_001047917.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 3181)
  AUTHORS   Sardiello,M., Annunziata,I., Roma,G. and Ballabio,A.
  TITLE     Sulfatases and sulfatase modifying factors: an exclusive and
            promiscuous relationship
  JOURNAL   Hum Mol Genet 14 (21), 3203-3217 (2005)
   PUBMED   16174644
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000002.1.
            
            On Oct 6, 2022 this sequence version replaced NM_001047917.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BN000745.1, SRR26360190.2715133.1
                                           [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA5760383,
                                           SAMEA5760386 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-207               JAXUCZ010000002.1  7363105-7363311     c
            208-337             JAXUCZ010000002.1  7358586-7358715     c
            338-497             JAXUCZ010000002.1  7356156-7356315     c
            498-774             JAXUCZ010000002.1  7337469-7337745     c
            775-946             JAXUCZ010000002.1  7336126-7336297     c
            947-1171            JAXUCZ010000002.1  7331246-7331470     c
            1172-1396           JAXUCZ010000002.1  7329902-7330126     c
            1397-3181           JAXUCZ010000002.1  7306181-7307965     c
FEATURES             Location/Qualifiers
     source          1..3181
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="2"
                     /map="2q11"
     gene            1..3181
                     /gene="Arsk"
                     /gene_synonym="RGD1310182"
                     /note="arylsulfatase family, member K"
                     /db_xref="GeneID:365619"
                     /db_xref="RGD:1310182"
     exon            1..207
                     /gene="Arsk"
                     /gene_synonym="RGD1310182"
                     /inference="alignment:Splign:2.1.0"
     CDS             82..1773
                     /gene="Arsk"
                     /gene_synonym="RGD1310182"
                     /EC_number="3.1.6.1"
                     /EC_number="3.1.6.18"
                     /note="ASK; arylsulfatase K; glucuronate-2-sulfatase"
                     /codon_start=1
                     /product="arylsulfatase K precursor"
                     /protein_id="NP_001041382.1"
                     /db_xref="GeneID:365619"
                     /db_xref="RGD:1310182"
                     /translation="MLLLLVSVIVALALVAPAPETQEKRLQVAQAPNVVLVASDSFDG
                     RLTFQPGSQVVKLPFINFMRARGTTFLNAYTNSPICCPSRAAMWSGLFTHLTESWNNF
                     KGLDPNYTTWMDVMEKHGYQTQKFGKLDYSSGHHSISNRVEAWTRDVAFLLRQEGRPI
                     INLIPDKNRRRVMDKDWQNTDKAIAWLRQVNSTKPFVLYLGLNLPHPYPSPSSGENFG
                     SSTFHTSLYWLEKVAYDAIKIPKWLALSEMHPVDYYSSYTKNCTGKFTENEIKNIRAF
                     YYAMCAETDAMLGEIILALHKLNLLQKTIVIYTSDHGEMAMEHRQFYKMSMYEASAHV
                     PILMMGPGIKANLQVPSLVSLVDIYPTMLDIAGIPLPLNLSGYSLLPLSSNTSANDQA
                     FRVHHPPWILSEFHGCNANASTYMLRTGQWKYIAYSDGTLVQPQLFDLSLDPDELTNI
                     ATEFPEITYSLDQQLRSVINYPKVSASVHRYNKEQFIMWKQSVAQNYSNYIAHLRWHQ
                     DWQKDPRKYENAIQRWLAIHSSPPTHSPLSLVHQWLTTHSSPIAVDNKKTFSSYT"
     exon            208..337
                     /gene="Arsk"
                     /gene_synonym="RGD1310182"
                     /inference="alignment:Splign:2.1.0"
     exon            338..497
                     /gene="Arsk"
                     /gene_synonym="RGD1310182"
                     /inference="alignment:Splign:2.1.0"
     exon            498..774
                     /gene="Arsk"
                     /gene_synonym="RGD1310182"
                     /inference="alignment:Splign:2.1.0"
     exon            775..946
                     /gene="Arsk"
                     /gene_synonym="RGD1310182"
                     /inference="alignment:Splign:2.1.0"
     exon            947..1171
                     /gene="Arsk"
                     /gene_synonym="RGD1310182"
                     /inference="alignment:Splign:2.1.0"
     exon            1172..1396
                     /gene="Arsk"
                     /gene_synonym="RGD1310182"
                     /inference="alignment:Splign:2.1.0"
     exon            1397..3181
                     /gene="Arsk"
                     /gene_synonym="RGD1310182"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 agagttcggt cccggctcat tactggagag caagtcacaa gagaccggct cagcggctgt
       61 ttccgaacgt ccaggcccgc gatgctgctg ctgttggttt cagtgatcgt ggcgttggcg
      121 ctcgtggcac cggctcccga aacacaggag aaaaggctgc aagtggccca ggcgcccaac
      181 gtggtgctgg tcgccagtga ctccttcgat ggaagactaa cattccaacc aggaagtcag
      241 gtagtaaaac ttcccttcat taacttcatg agagcacgtg gcaccacctt cctaaatgcc
      301 tacactaact ctcccatctg ctgtccatca cgtgcagcaa tgtggagtgg ccttttcact
      361 cacttaacag aatcttggaa taattttaag ggtctggatc caaattacac aacatggatg
      421 gatgtcatgg agaagcatgg ctatcagaca cagaaatttg gaaaactgga ctattcttca
      481 gggcatcatt ccattagtaa ccgtgtggaa gcatggacaa gagacgttgc attcttgctg
      541 cgacaagagg gcaggcccat aattaatctt atccctgata agaatagaag gagagtgatg
      601 gacaaggact ggcagaatac agacaaagca attgcttggc taagacaggt taactccacc
      661 aaaccatttg tcctttactt gggattgaat ttgccacatc cttacccttc accatcttca
      721 ggagaaaact ttggctcttc tacatttcac acttctcttt actggcttga aaaggtagct
      781 tacgatgcaa tcaaaatccc aaagtggttg gctttgtcag aaatgcatcc tgtggattat
      841 tactcctcct acacaaaaaa ctgcactggg aagtttactg aaaatgaaat taagaacatt
      901 agagcatttt attatgctat gtgtgctgag acagatgcca tgctaggtga aattattttg
      961 gctcttcaca agttaaatct tcttcagaaa actattgtta tatatacttc ggaccatggc
     1021 gagatggcta tggaacaccg ccagttttac aaaatgagta tgtatgaagc tagtgcccat
     1081 gttcctattt tgatgatggg accaggaatt aaggccaacc tacaagtacc aagtcttgtt
     1141 tctcttgtgg atatttaccc tactatgctt gacattgctg ggatccctct gccactgaac
     1201 ctgagtggat actccttgtt gccactgtcg tcaaatacat ctgcaaatga ccaggcattc
     1261 agagtccacc atccaccttg gattctgagt gaattccatg gatgcaatgc aaatgcttcc
     1321 acctacatgc tgagaactgg ccagtggaag tatatagcct actctgacgg tactttggta
     1381 cagcctcagc tcttcgatct ttcactggac ccagatgagc taacaaacat tgctacagaa
     1441 tttccagaaa ttacttattc actggaccag cagcttcgtt ctgttataaa ctaccctaaa
     1501 gtgtcagctt cagtccatcg gtacaataaa gagcagttta tcatgtggaa acaaagcgta
     1561 gcacaaaatt actcaaatta tatagcacac cttaggtggc atcaagattg gcaaaaagac
     1621 ccaaggaagt atgaaaatgc aatccaacgg tggcttgcaa tccactccag tccaccaact
     1681 cacagcccac tctccttagt ccaccagtgg ctcacaaccc actcttctcc aatagcagta
     1741 gacaataaaa aaactttctc aagctataca tgaatacgtt agtgcatact gagctgaaat
     1801 agcctcagtg attgccaatt ttacttactt tcaaaataca tactgtatct caagtgccaa
     1861 tgaatacaga actcacattg tcagaactag ttgtactaaa accttattgt tgcagagctc
     1921 tgacagttta acatcagaag tatttaaaga atagaagcag gcactcttat ttccctggat
     1981 gatacagaat atgaactatt ttaacagcca tcagttatta tttatgaatc gtatttcgtg
     2041 acttactagt tcttttatga aactctttag atatatttga tatgttagaa ctacttaatt
     2101 ggatatagac tctaatatag ttgattttag ttttgttgtt gttgttattt taaaaaaaag
     2161 aatatgaagc tcccttcctt tcctggtcag caccctccaa agggcaacta caatcacctt
     2221 gtgtcctttg tggacaagct acatatagtc atcaaccaaa tgaatatatt atttacatgg
     2281 acatgcaggc atacacacaa ttgataatgt tctttgtagg gttttttctg gcatattgtg
     2341 ctctggcttt attttctagt tccaattaat aatagatgct gaaatgtaaa attgctgagc
     2401 agggatttac aaaaatttct gtcgcttttc tcaagttgtt tctaaagaca ttctagcagt
     2461 tggcattccc accagtagat agctaatatt ttatctttat ttactgtgag tactgacatt
     2521 tttttcatag atctaataac cagtaaaatt tgcatcagaa tgaccttcca tatgtctctt
     2581 ggccattttc tctataggtt attagcattg tctttctctt acatgcatac ttttagatat
     2641 tagccttttg aaaagaaaaa aaggactaga gagattgttc tgtggttcag agcacttgct
     2701 actcatccag aggacaaagc tccaattatt gacacctata cagtgcctca caacttgtgt
     2761 ataactccaa ttcaggggag ccagtgctct ttctggcccc caagggtgcc aggcaaacat
     2821 gtagtgcaca gactaaatgc aggcaagtct cattcatata aaatttttaa aataataaac
     2881 aaatactttt tttaaaaaaa ctactggaaa tagtatttac tttgtctttt gctattgacc
     2941 cggggaaaat ctgtattttc ttgtaacata tttataaatc ttagtaccaa ataaatattg
     3001 tgatttttaa aattaaaata ttcattaaaa tgtttataaa tctttatttt gtagctttta
     3061 gaatttgtgt cctattatga atgttcttct ctccgatgct ctgatgttca taaagttttg
     3121 tttttagccc ttagatcttt gatccatgta agattcttta catattaaag atctgacttt
     3181 a
//
