LOCUS       NP_001041352             597 aa            linear   ROD 01-APR-2024
DEFINITION  arylsulfatase J [Rattus norvegicus].
ACCESSION   NP_001041352 XP_001076005 XP_227873
VERSION     NP_001041352.1
DBSOURCE    REFSEQ: accession NM_001047887.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (residues 1 to 597)
  AUTHORS   Sardiello,M., Annunziata,I., Roma,G. and Ballabio,A.
  TITLE     Sulfatases and sulfatase modifying factors: an exclusive and
            promiscuous relationship
  JOURNAL   Hum Mol Genet 14 (21), 3203-3217 (2005)
   PUBMED   16174644
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000002.1.
            
            On or before Sep 8, 2006 this sequence version replaced
            XP_227873.3, XP_001076005.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BN000740.1, SRR26360186.76487.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760386, SAMEA5760389
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..597
                     /organism="Rattus norvegicus"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="2"
                     /map="2q42"
     Protein         1..597
                     /product="arylsulfatase J"
                     /EC_number="3.1.6.12"
                     /calculated_mol_wt=67392
     Region          74..507
                     /region_name="4-S"
                     /note="N-acetylgalactosamine 4-sulfatase, also called
                     arylsulftase B; cd16029"
                     /db_xref="CDD:293753"
     Site            order(82..83,120,174,176,267,325..326)
                     /site_type="active"
                     /note="putative active site [active]"
                     /db_xref="CDD:293753"
     Site            order(82..83,120,174,176,267,326)
                     /site_type="other"
                     /note="putative substrate binding site [chemical binding]"
                     /db_xref="CDD:293753"
     CDS             1..597
                     /gene="Arsj"
                     /gene_synonym="RGD1307640"
                     /coded_by="NM_001047887.2:853..2646"
                     /db_xref="GeneID:311013"
                     /db_xref="RGD:1307640"
ORIGIN      
        1 maprdsaepl pplfpqarvw pgkmvamgal agfwvlslit ygylswgqdl eeegslraqv
       61 eerpeagtav tsqphlifil addqgfrdvg yhgseiktpt ldklaaegvk lenyyvqpic
      121 tpsrsqfitg kyqihtglqh siirptqpnc lpldnatlpq klkevgysth mvgkwhlgfy
      181 rkdcmptkrg fdtffgsllg sgdyythykc dspgvcgydl yendnaawdy dngiystqmy
      241 tqrvqqilas hdptkplfly vayqavhspl qapgryfehy rsiininrrr yaamlsclde
      301 aihnvtlalk rygfynnsii iyssdnggqp taggsnwplr gskgtywegg iravgfvhsp
      361 llknkgtvck elvhitdwyp tlislaegqi dediqldgyd iwetiseglr sprvdilhni
      421 dpiytkakng swaagygiwn taiqsairvq hwklltgnpg ysdwvppqaf snlgpnrwhn
      481 eritlstgks iwlfnitadp yervdlssry pgivkkllrr lsqfnktavp vryppkdprs
      541 nprlnggvwg pwykeeskkk ktnktkakkm qkkskartrk qraarsstkc hprvttg
//
