LOCUS       NM_001047877            3172 bp    mRNA    linear   ROD 31-MAR-2024
DEFINITION  Rattus norvegicus arylsulfatase G (Arsg), mRNA.
ACCESSION   NM_001047877 XM_001081596 XM_221064
VERSION     NM_001047877.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 3172)
  AUTHORS   Frese,M.A., Schulz,S. and Dierks,T.
  TITLE     Arylsulfatase G, a novel lysosomal sulfatase
  JOURNAL   J Biol Chem 283 (17), 11388-11395 (2008)
   PUBMED   18283100
REFERENCE   2  (bases 1 to 3172)
  AUTHORS   Sardiello,M., Annunziata,I., Roma,G. and Ballabio,A.
  TITLE     Sulfatases and sulfatase modifying factors: an exclusive and
            promiscuous relationship
  JOURNAL   Hum Mol Genet 14 (21), 3203-3217 (2005)
   PUBMED   16174644
REFERENCE   3  (bases 1 to 3172)
  AUTHORS   Ferrante,P., Messali,S., Meroni,G. and Ballabio,A.
  TITLE     Molecular and biochemical characterisation of a novel sulphatase
            gene: Arylsulfatase G (ARSG)
  JOURNAL   Eur J Hum Genet 10 (12), 813-818 (2002)
   PUBMED   12461688
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000010.1.
            
            On Oct 29, 2022 this sequence version replaced NM_001047877.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BN000738.1, SRR26643298.64890.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760386
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-894               JAXUCZ010000010.1  94963380-94964273
            895-1082            JAXUCZ010000010.1  94990428-94990615
            1083-1130           JAXUCZ010000010.1  94994417-94994464
            1131-1242           JAXUCZ010000010.1  94995952-94996063
            1243-1380           JAXUCZ010000010.1  94998283-94998420
            1381-1577           JAXUCZ010000010.1  95004563-95004759
            1578-1658           JAXUCZ010000010.1  95005788-95005868
            1659-1767           JAXUCZ010000010.1  95017522-95017630
            1768-1888           JAXUCZ010000010.1  95027745-95027865
            1889-1979           JAXUCZ010000010.1  95032925-95033015
            1980-3172           JAXUCZ010000010.1  95041254-95042446
FEATURES             Location/Qualifiers
     source          1..3172
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="10"
                     /map="10q32.1"
     gene            1..3172
                     /gene="Arsg"
                     /gene_synonym="RGD1306571"
                     /note="arylsulfatase G"
                     /db_xref="GeneID:303631"
                     /db_xref="RGD:1306571"
     exon            1..894
                     /gene="Arsg"
                     /gene_synonym="RGD1306571"
                     /inference="alignment:Splign:2.1.0"
     CDS             677..2257
                     /gene="Arsg"
                     /gene_synonym="RGD1306571"
                     /EC_number="3.1.6.1"
                     /EC_number="3.1.6.15"
                     /note="ASG; N-sulfoglucosamine-3-sulfatase"
                     /codon_start=1
                     /product="arylsulfatase G precursor"
                     /protein_id="NP_001041342.1"
                     /db_xref="GeneID:303631"
                     /db_xref="RGD:1306571"
                     /translation="MGWLFLKVLLVGMVFSGLLYPFVDFSISGETRAPRPNIVIILAD
                     DMGWGDLGANWAETKDTTNLDKMASEGMRFVDFHAAASTCSPSRASLLTGRLGLRNGV
                     THNFAVTSVGGLPLNETTLAEVLQQAGYVTAMIGKWHLGHHGSYHPSFRGFDYYFGIP
                     YSNDMGCTDNPGYNYPPCPACPQSDGRWRNPDRDCYTDVALPLYENLNIVEQPVNLSG
                     LAQKYAERAVEFIEQASTSGRPFLLYVGLAHMHVPLSVTPPLANPQSQRLYRASLQEM
                     DSLVGQIKDKVDHVAKENTLLWFAGDNGPWAQKCELAGSMGPFSGLWQTHQGGSPAKQ
                     TTWEGGHRVPALAYWPGRVPVNVTSTALLSLLDIFPTVIALAGASLPPNRKFDGVDVS
                     EVLFGKSQTGHRVLFHPNSGAAGEYGALQTVRLDRYKAFYITGGAKACDGGVGPEQHH
                     VSPLIFNLEDDAAESSPLQKGSPEYQELLPKVTRVLADVLQDIADDNSSQADYTQDPS
                     VTPCCNPYQITCRCQPGE"
     exon            895..1082
                     /gene="Arsg"
                     /gene_synonym="RGD1306571"
                     /inference="alignment:Splign:2.1.0"
     exon            1083..1130
                     /gene="Arsg"
                     /gene_synonym="RGD1306571"
                     /inference="alignment:Splign:2.1.0"
     exon            1131..1242
                     /gene="Arsg"
                     /gene_synonym="RGD1306571"
                     /inference="alignment:Splign:2.1.0"
     exon            1243..1380
                     /gene="Arsg"
                     /gene_synonym="RGD1306571"
                     /inference="alignment:Splign:2.1.0"
     exon            1381..1577
                     /gene="Arsg"
                     /gene_synonym="RGD1306571"
                     /inference="alignment:Splign:2.1.0"
     exon            1578..1658
                     /gene="Arsg"
                     /gene_synonym="RGD1306571"
                     /inference="alignment:Splign:2.1.0"
     exon            1659..1767
                     /gene="Arsg"
                     /gene_synonym="RGD1306571"
                     /inference="alignment:Splign:2.1.0"
     exon            1768..1888
                     /gene="Arsg"
                     /gene_synonym="RGD1306571"
                     /inference="alignment:Splign:2.1.0"
     exon            1889..1979
                     /gene="Arsg"
                     /gene_synonym="RGD1306571"
                     /inference="alignment:Splign:2.1.0"
     exon            1980..3172
                     /gene="Arsg"
                     /gene_synonym="RGD1306571"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ggggaagaaa ctgacgagcc agttaaacac tcgaagacga aggaaaacat ctgttggcgt
       61 ggaaaagtga ttatttccca agctaccgag taaaacacaa caggcctggc tgtttgaact
      121 ctggtttctt gtcagatttt cttctttcag gaaaccttac agaaagctcc caccatctgg
      181 aactcagaga ctcatctggg agctgactgt ggcttctaga agatccaggt gttctgcaga
      241 tgtgagaatg tatcccacag tcaccagatg aagccctaag cagatgcaag gcttgtgtta
      301 tagccttagc ctccctgagt gcaaagggtc acttcctggc taagtggcca ggagcggtta
      361 ttgacgttga tgtctgaatg ctgcacctga ccagtcatct gattaggctg tgatgagaag
      421 acatcttgag gggaccaacc cgactttggg gggggaccac attcttgact ttcttagatt
      481 aggattccat atggggacct ggtttctgta gcccctgcca tccctgtagc catcgctaac
      541 accagtgtgt tcttgacaac tggactcctt ggtgacttcc tgcactgaag gtgaacaaag
      601 agaaaactct tcgagagatt catgtggtgg ccagatatca cttcacggag acaacaggaa
      661 gtcgttgtgt cctaccatgg gctggctctt tctaaaggtt ttgttggttg gcatggtttt
      721 ttctggactt ctctacccgt tcgtggattt ctctatcagt ggggaaacaa gagcccccag
      781 accaaacatt gtgatcattt tggctgatga catgggatgg ggtgatctgg gagcaaactg
      841 ggcagaaaca aaggatacca ccaatcttga caaaatggct tctgaaggaa tgaggtttgt
      901 agacttccac gcagctgctt ctacctgctc gccgtcccga gcctccctgc ttaccggccg
      961 gctgggtcta cggaatggag tcacgcacaa ctttgcagtc acctctgtag gggggcttcc
     1021 actcaacgag accaccttgg cagaggtgct gcagcaggcc ggttacgtca ctgccatgat
     1081 aggcaagtgg catcttgggc atcatggctc ttatcacccc agtttccgtg gcttcgatta
     1141 ctactttggt atcccgtata gcaacgacat gggctgtacc gacaaccccg gctacaacta
     1201 ccctccttgc ccagcatgtc cgcaaagcga tggccgatgg aggaaccctg acagggactg
     1261 ttacacagat gtggcccttc ctctctatga aaacctgaac atcgtagagc agccggtgaa
     1321 cctgagcggc cttgcacaga agtatgcaga gagggcagtg gagttcattg agcaggcaag
     1381 caccagtggg agacccttcc tgctctatgt gggcctggcc cacatgcacg tgcctttgtc
     1441 tgtaactcca ccgttggcca acccacagag ccaaaggctg taccgtgcaa gtctccaaga
     1501 gatggacagt ctggtagggc agatcaagga caaagtggac cacgtggcaa aagaaaacac
     1561 actcctctgg tttgcaggag acaacggccc gtgggctcag aagtgcgagc tggcaggcag
     1621 catgggcccc ttctccggat tgtggcaaac ccatcaaggg ggaagtccag ccaagcagac
     1681 cacctgggaa ggtgggcatc gggtcccagc actggcttac tggcctggca gagttccagt
     1741 caatgttacc agcactgcct tgttaagctt gcttgacatc ttccccaccg tgatagccct
     1801 ggcgggagcc agcttgcccc caaaccggaa gtttgatggt gtggacgtct ctgaagtgct
     1861 ctttggcaag tcacaaacgg ggcacagggt actgttccac cccaacagtg gggctgctgg
     1921 agagtacggc gccctgcaga ctgtccgcct ggaccgttac aaggccttct acataacggg
     1981 tggagccaaa gcttgtgatg ggggcgtggg tcccgagcag caccacgtct cccctctcat
     2041 tttcaaccta gaagatgatg ctgctgaaag ttcccctcta cagaagggaa gccccgagta
     2101 ccaggagctg ctgccgaagg tcaccagggt tcttgcagat gtccttcaag acatcgctga
     2161 tgacaacagc tctcaagcag actacactca ggatccttcc gtgacccctt gctgtaaccc
     2221 ttatcaaatt acctgccgtt gccaacccgg ggaatgacag gtcattcccc gacccccacc
     2281 cggtgagaaa cactatctgg aaattttaga caggtgggtt tacttccaaa cctcagtttg
     2341 gtcgtggaag tcagttttag aaagggagtt gcagaatttg gttaggaagc tacagtgtta
     2401 cctctctgtg tgtggactgt ctcctccgca tgcaggcttg aaaagcactg agcactggct
     2461 cagaggtcat ggatacaaga gggcactaga gggctatgga gtcaccgccc aagccctggg
     2521 tttaaagctt aggcaatgac ttaaatctca gttgcaagtt ggtcttgaag gttaaagtaa
     2581 cacatgaagt tgcctgtgta tctctgacac caggcagatc ctcaatttaa ttggcccttg
     2641 cagcacaaac tcatctggct tgctggtata cagagcttgg ccctcttcaa tatgcatacg
     2701 aatctctgag gatcttgcac aatgcagatt ctggaagtgg gtgtgtgtct gggagcctac
     2761 agcgttgccg gattcctttg agacgccttg agcaagcaca gagctaaact aagtgaggtc
     2821 ttcccaggcc ttggagcaga actcatgatc cttccctctt gttaatgtcg agtggatgta
     2881 tcataaagag ttaaagtttg gggccgaagc ggtggtccat tggttaaggg cgcgacctgt
     2941 tcagttccca gcacctatat ggtagcttaa actgtctata gctccaattc caggggacct
     3001 catactcttc tctggcttct cagaatgcca ggcacacgcg tgatgtatgc acaggtaggt
     3061 gagacactca tatattaaaa cataatcttt caagaaaaaa aaaagatttg agacttcttc
     3121 ccagccagtc cctaaaactt ctaagaaata aaataaaaat gtaaacaact ca
//
