LOCUS       NM_001107530            1857 bp    mRNA    linear   ROD 26-FEB-2024
DEFINITION  Rattus norvegicus actin-related protein 2/3 complex inhibitor
            (Arpin), mRNA.
ACCESSION   NM_001107530 XM_001065822 XM_218824
VERSION     NM_001107530.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1857)
  AUTHORS   Dang I, Gorelik R, Sousa-Blin C, Derivery E, Guerin C, Linkner J,
            Nemethova M, Dumortier JG, Giger FA, Chipysheva TA, Ermilova VD,
            Vacher S, Campanacci V, Herrada I, Planson AG, Fetics S, Henriot V,
            David V, Oguievetskaia K, Lakisic G, Pierre F, Steffen A, Boyreau
            A, Peyrieras N, Rottner K, Zinn-Justin S, Cherfils J, Bieche I,
            Alexandrova AY, David NB, Small JV, Faix J, Blanchoin L and
            Gautreau A.
  TITLE     Inhibitory signalling to the Arp2/3 complex steers cell migration
  JOURNAL   Nature 503 (7475), 281-284 (2013)
   PUBMED   24132237
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH473980.1.
            
            On or before Oct 4, 2007 this sequence version replaced
            XM_218824.4, XM_001065822.1.
            
            ##Evidence-Data-START##
            RNAseq introns :: mixed sample support SAMD00132261, SAMD00132262
                              [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1857
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q31"
     gene            1..1857
                     /gene="Arpin"
                     /gene_synonym="RGD1311021"
                     /note="actin-related protein 2/3 complex inhibitor"
                     /db_xref="GeneID:308765"
                     /db_xref="RGD:1311021"
     exon            1..170
                     /gene="Arpin"
                     /gene_synonym="RGD1311021"
                     /inference="alignment:Splign:2.1.0"
     CDS             79..759
                     /gene="Arpin"
                     /gene_synonym="RGD1311021"
                     /codon_start=1
                     /product="arpin"
                     /protein_id="NP_001101000.1"
                     /db_xref="GeneID:308765"
                     /db_xref="RGD:1311021"
                     /translation="MSRIYHDSALRNKAVQSVRLPGTWDPTTHQGGSGVLLEGELVDV
                     SRHSILDAHGRKERYYVLYIQPSCIHRRKFDPKGNEIEPNFSATRKVNTGFLMSSFKV
                     EAKGDTDRLTLEVLKGLVNKPELLELTESLTPDQTVAFWMPESEMEVMELELGTGVRL
                     KTRGDGPFIDSLAKLELGTVTKCNFAGDGKTGASWTDNIMAQKSSERNTAEIREQGDG
                     AEDEEWDD"
     exon            171..246
                     /gene="Arpin"
                     /gene_synonym="RGD1311021"
                     /inference="alignment:Splign:2.1.0"
     exon            247..379
                     /gene="Arpin"
                     /gene_synonym="RGD1311021"
                     /inference="alignment:Splign:2.1.0"
     exon            380..586
                     /gene="Arpin"
                     /gene_synonym="RGD1311021"
                     /inference="alignment:Splign:2.1.0"
     exon            587..750
                     /gene="Arpin"
                     /gene_synonym="RGD1311021"
                     /inference="alignment:Splign:2.1.0"
     exon            751..1857
                     /gene="Arpin"
                     /gene_synonym="RGD1311021"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 tccaagctcc tgtccctgag gtgccccgcc ccacgcgccg cctgcttcct ggagctgcgg
       61 ggcctccgcg tggggaaaat gagccgcatc taccacgaca gtgccctccg caacaaggcg
      121 gtgcagagcg tgcgactgcc cgggacctgg gaccccacca cccaccaagg gggaagtggc
      181 gtattgctgg agggagaact cgtggatgta tcccggcaca gcatcttgga tgcccatggc
      241 aggaaggaac gctactatgt gctgtatatc cagcccagtt gtatccaccg gcgtaagttt
      301 gaccccaagg gaaatgaaat tgagcccaac ttcagtgcca ccaggaaggt gaacacaggc
      361 ttcctcatgt catctttcaa ggtggaggcc aagggcgaca cagaccggct caccctggag
      421 gtgctaaagg gcctggtaaa taagcctgag ctgctggagt tgacagagag cctcacccca
      481 gaccagacag tcgctttctg gatgcctgag tcagagatgg aggtcatgga actcgaactg
      541 gggactggag tgcggttaaa aactcggggt gatggcccct tcatagattc cttagccaaa
      601 ctggagctgg ggacagtgac caagtgtaat tttgctggtg atggaaagac gggagcatcc
      661 tggacagaca atatcatggc ccaaaagtct tcagagagga acacagcgga gatccgagag
      721 caaggagatg gggcagagga tgaggaatgg gacgattgag gtgcctcctc tcctaccagc
      781 gtctgtgatg gtgtcactga gaagtggcca cgccgacttc taccttggag agatcggtct
      841 gtcaagctga ttaccactta atacactctg cgaaaatcaa atccaagacc tcactcaata
      901 cgcaccaagg gtccagctct ggcttttata tgtctgtgtc cttctttgga tgcaaggcta
      961 ttccccagac ctattgtctc ctgtgttcct ttccctaggt ggtggacatg tactgggtga
     1021 gtcctccaag gcacacaatt gacaaaggct ccttgtctga gtgcagagga gctccgggag
     1081 taggagagca ggctcctttc attcctgtgc ttttatcctt tccttccttt ctaccccgtg
     1141 tgagccttct tgttgtgcct ctgttctctt gtccctccat cttctcttcc gtgctccact
     1201 cccaagacac cacttcttta tttctatttg gttctcaacc tccatggggt ttcctgcctt
     1261 agacctctgt cttggggttc ctactgctct gataaaacat catgaccaga agaaacttgg
     1321 ggaggaaagg aaaggatttg ttttactcac agttccatag aacagttcat catcaaaagc
     1381 agtgagggca ggaactcaag caaggcagga accggaggca ggagcaggat ccatggtgtg
     1441 ctgcagactg gcttgctcag cctgctttct tctagaacca gggccaccag cccagtaatg
     1501 gtactaccta cgacgggccg ggctctcccc catcaaccac taattacaaa aatgtcctac
     1561 agtcggatct catggagata ttttctcaat ggaggttccc tctttcaggg tacactacct
     1621 tctgtcaaat tgacaaaaag ctagtcagca cagacctatc tggctgctgt cctaaacatg
     1681 tcgttcttgg gaaggcctac agcctttcta gcagtgtctg gttggtccac aggtcttgac
     1741 tcattccact gggtcaactt tatatatatg tattttttta ttatttttta aatagtgctg
     1801 gtactcaagc ctagcactgc atgcttgcta agtgagtgac ctaccacagt ctacaca
//
