LOCUS       NM_001024332            2770 bp    mRNA    linear   ROD 12-NOV-2024
DEFINITION  Rattus norvegicus ARF like GTPase 8B (Arl8b), mRNA.
ACCESSION   NM_001024332 XM_575632
VERSION     NM_001024332.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2770)
  AUTHORS   Vukoja,A., Rey,U., Petzoldt,A.G., Ott,C., Vollweiter,D.,
            Quentin,C., Puchkov,D., Reynolds,E., Lehmann,M., Hohensee,S.,
            Rosa,S., Lipowsky,R., Sigrist,S.J. and Haucke,V.
  TITLE     Presynaptic Biogenesis Requires Axonal Transport of
            Lysosome-Related Vesicles
  JOURNAL   Neuron 99 (6), 1216-1232 (2018)
   PUBMED   30174114
REFERENCE   2  (bases 1 to 2770)
  AUTHORS   Pu,J., Schindler,C., Jia,R., Jarnik,M., Backlund,P. and
            Bonifacino,J.S.
  TITLE     BORC, a multisubunit complex that regulates lysosome positioning
  JOURNAL   Dev Cell 33 (2), 176-188 (2015)
   PUBMED   25898167
REFERENCE   3  (bases 1 to 2770)
  AUTHORS   Schiefermeier,N., Scheffler,J.M., de Araujo,M.E., Stasyk,T.,
            Yordanov,T., Ebner,H.L., Offterdinger,M., Munck,S., Hess,M.W.,
            Wickstrom,S.A., Lange,A., Wunderlich,W., Fassler,R., Teis,D. and
            Huber,L.A.
  TITLE     The late endosomal p14-MP1 (LAMTOR2/3) complex regulates focal
            adhesion dynamics during cell migration
  JOURNAL   J Cell Biol 205 (4), 525-540 (2014)
   PUBMED   24841562
REFERENCE   4  (bases 1 to 2770)
  AUTHORS   Ghosh,D., Lippert,D., Krokhin,O., Cortens,J.P. and Wilkins,J.A.
  TITLE     Defining the membrane proteome of NK cells
  JOURNAL   J Mass Spectrom 45 (1), 1-25 (2010)
   PUBMED   19946888
REFERENCE   5  (bases 1 to 2770)
  AUTHORS   Gonzales,P.A., Pisitkun,T., Hoffert,J.D., Tchapyjnikov,D.,
            Star,R.A., Kleta,R., Wang,N.S. and Knepper,M.A.
  TITLE     Large-scale proteomics and phosphoproteomics of urinary exosomes
  JOURNAL   J Am Soc Nephrol 20 (2), 363-379 (2009)
   PUBMED   19056867
REFERENCE   6  (bases 1 to 2770)
  AUTHORS   Okai,T., Araki,Y., Tada,M., Tateno,T., Kontani,K. and Katada,T.
  TITLE     Novel small GTPase subfamily capable of associating with tubulin is
            required for chromosome segregation
  JOURNAL   J Cell Sci 117 (Pt 20), 4705-4715 (2004)
   PUBMED   15331635
REFERENCE   7  (bases 1 to 2770)
  AUTHORS   Secombe,J. and Parkhurst,S.M.
  TITLE     Drosophila Topors is a RING finger-containing protein that
            functions as a ubiquitin-protein isopeptide ligase for the hairy
            basic helix-loop-helix repressor protein
  JOURNAL   J Biol Chem 279 (17), 17126-17133 (2004)
   PUBMED   14871887
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC081947.1.
            
            On May 27, 2005 this sequence version replaced XM_575632.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC081947.1, FQ214780.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132261, SAMD00132262
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..2770
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="4"
                     /map="4q41"
     gene            1..2770
                     /gene="Arl8b"
                     /note="ARF like GTPase 8B"
                     /db_xref="GeneID:500282"
                     /db_xref="RGD:1562830"
     exon            1..306
                     /gene="Arl8b"
                     /inference="alignment:Splign:2.1.0"
     CDS             184..744
                     /gene="Arl8b"
                     /EC_number="3.6.5.2"
                     /note="ADP-ribosylation factor-like 8B; ADP-ribosylation
                     factor like GTPase 8B"
                     /codon_start=1
                     /product="ADP-ribosylation factor-like protein 8B"
                     /protein_id="NP_001019503.1"
                     /db_xref="GeneID:500282"
                     /db_xref="RGD:1562830"
                     /translation="MLALISRLLDWFRSLFWKEEMELTLVGLQYSGKTTFVNVIASGQ
                     FSEDMIPTVGFNMRKVTKGNVTIKIWDIGGQPRFRSMWERYCRGVNAIVYMIDAADRE
                     KIEASRNELHNLLDKPQLQGIPVLVLGNKRDLPNALDEKQLIEKMNLSAIQDREICCY
                     SISCKEKDNIDITLQWLIQHSKSRRS"
     exon            307..387
                     /gene="Arl8b"
                     /inference="alignment:Splign:2.1.0"
     exon            388..461
                     /gene="Arl8b"
                     /inference="alignment:Splign:2.1.0"
     exon            462..555
                     /gene="Arl8b"
                     /inference="alignment:Splign:2.1.0"
     exon            556..623
                     /gene="Arl8b"
                     /inference="alignment:Splign:2.1.0"
     exon            624..694
                     /gene="Arl8b"
                     /inference="alignment:Splign:2.1.0"
     exon            695..2729
                     /gene="Arl8b"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ggcgaatcat atgacccgct gggcttcctg gctccggccg tcgcagcctc ctatctgtgt
       61 ctacccgagt cgcgccgggg ggcccgctga agagccgttg gcgggttccg ggccgatacc
      121 cgctcgtggg aagcagtgtc tgtcgtcgtc cgcgcccgtc cccgctcgct gccggccgcc
      181 gccatgctgg cgctcatctc ccgcctgctg gactggttcc gctcgctctt ctggaaggag
      241 gagatggaac tgacgctggt ggggctgcag tactctggca agaccacttt cgtcaatgtc
      301 atcgcgtctg gtcaattcag tgaagatatg atacccaccg tgggcttcaa catgaggaaa
      361 gtaactaaag gtaacgtcac aataaagatc tgggacatag gagggcagcc ccggttccgg
      421 agcatgtggg agcggtattg cagaggcgtc aatgcaattg tttacatgat agatgctgca
      481 gatcgagaaa agatagaagc ctctcgaaat gaactgcaca atcttctaga taagccacag
      541 ttacaaggaa tcccagtact agtacttgga aacaagagag atcttccaaa tgccttggat
      601 gagaaacagc taattgaaaa aatgaacctg tctgctattc aagatagaga aatttgctgc
      661 tattcaattt cttgcaaaga aaaggataat atagatatca cacttcagtg gcttattcaa
      721 cactcaaaat cccggagaag ctgagacatc ttctgagtct tccagtcctt cttggctata
      781 atcctagaac tactgtcgtt cctctgaagt acttcccaga acatggtcct tcctaaaccc
      841 aagaaattgc ctttttcaga gtttatttct catgtgcact gctgaagatg tgtattccta
      901 tccttcataa caaatcagct ggagttgtca tgataaaagt cagcgcacac taaaaggctt
      961 cacacatgtg tcaagtgtgt tgaggcctgt tctctttctt tctttctatt ttaaaaacac
     1021 ccacattttt gaccatccta attaagaaaa ttgcatatta ccattctggt ctttctgggc
     1081 cagatttttg tagtggtttt cagtaaatgt ctacctattt cattacagag tccagtagct
     1141 tctactggta ctgacttgat gcagcatgga attcctagtg ccacacacag tatttagaca
     1201 aactttaagc ctgacttctg tgggatacgg gcatactgtt tatcccatct cacacatgca
     1261 tgtgaaatgt agacttaaac tgtaggaata attggtctgc cagtagttaa cagaggcacc
     1321 aggtcagaac agaacactgg agatttccta cctggtgagt tttaaaaact gctgtctgaa
     1381 actcctttgt caccagatag cactggggag atggggagga gttacagcat gctcttttgt
     1441 atctgtccag atcatcagtt tttttccccc ttttaacaca cttttttaaa gggatgggaa
     1501 tcacagattt tctttttccc aaaggctttc atgagtttag agcattccag ctagtgtaat
     1561 aaacccttta agaatgtcta acttcatatg aacacacgtc tgttatttgt ctccaatcac
     1621 ccaccctgtg ctgctgcatg atacccttaa ctcctgactt tttatatcta gtcatgaagt
     1681 tgactttcag cacaaaggat acttataaac aaattcttat ttttttctta ccaatgtaag
     1741 gtttggcact cttttcactg gtgccactcg acttactgat tgtgacaact ctaggcctgc
     1801 ctgcttcatc taatgtaatc atgtgcaacg tctgcaggtt gtttaatgac cggccacacc
     1861 gagaacagag gaaccaatgc tgtttattgt ttgcttctat gatacagagc tgtacaaaaa
     1921 cttacaatga acatattttg tagcttagtg atccacgtac ataaagggac atattaataa
     1981 tggttgactt agaaaccgtt actcatgccg atgtagtaga taaagcccat ggcccacctg
     2041 cttatgtgtt gctcacactg tgtgtgattt gtctcttctg tcaagcagca cccatgtcaa
     2101 cagtacatat tcatatgtgt tgagcactcc aagtgtagtc aatagtacct gaataccgct
     2161 ttaatttata gactgccacg gccttaagaa cattctgtac agataactgc actgtgttgc
     2221 acagacacta cttgttttct ccattcacgt ttttaatgag tagaatctgg gctttaaagt
     2281 tctcttctta ttttcatgga ggcatgttgc actcttcctg aatgggatag gtggtttaaa
     2341 taaaaggata tttaaacttt gctcctgtag ccggacatga ctaatggtca ttgtgaacca
     2401 tttcaaagaa tgtggcaact tgcttgtgcc tagaaggagg gattggaacc agaatgttta
     2461 actaagcggg gactgtgtag ctttttgtta attgacctat agaaacctta atttgtttat
     2521 gtgtctttcc attgctttcc agcatttcag gacatctaaa agctactacc aacattttcc
     2581 tgtgcataac ctctgcatgt gaaaacctaa cagttactga actttgtaaa tacgtacatt
     2641 ttttatttag gtgtggatgc attttttgtc tgtttactgc tcctctcagc tttattcaat
     2701 aaacttgcat tttgagggtt gcattgacaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
     2761 aaaaaaaaaa
//
