LOCUS       NM_022700                800 bp    mRNA    linear   ROD 12-NOV-2024
DEFINITION  Rattus norvegicus ARF like GTPase 3 (Arl3), mRNA.
ACCESSION   NM_022700
VERSION     NM_022700.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 800)
  AUTHORS   Alkanderi,S., Molinari,E., Shaheen,R., Elmaghloob,Y., Stephen,L.A.,
            Sammut,V., Ramsbottom,S.A., Srivastava,S., Cairns,G., Edwards,N.,
            Rice,S.J., Ewida,N., Alhashem,A., White,K., Miles,C.G., Steel,D.H.,
            Alkuraya,F.S., Ismail,S. and Sayer,J.A.
  TITLE     ARL3 Mutations Cause Joubert Syndrome by Disrupting Ciliary Protein
            Composition
  JOURNAL   Am J Hum Genet 103 (4), 612-620 (2018)
   PUBMED   30269812
REFERENCE   2  (bases 1 to 800)
  AUTHORS   Lokaj,M., Kosling,S.K., Koerner,C., Lange,S.M., van Beersum,S.E.,
            van Reeuwijk,J., Roepman,R., Horn,N., Ueffing,M., Boldt,K. and
            Wittinghofer,A.
  TITLE     The Interaction of CCDC104/BARTL1 with Arl3 and Implications for
            Ciliary Function
  JOURNAL   Structure 23 (11), 2122-2132 (2015)
   PUBMED   26455799
REFERENCE   3  (bases 1 to 800)
  AUTHORS   Kim,H., Xu,H., Yao,Q., Li,W., Huang,Q., Outeda,P., Cebotaru,V.,
            Chiaravalli,M., Boletta,A., Piontek,K., Germino,G.G., Weinman,E.J.,
            Watnick,T. and Qian,F.
  TITLE     Ciliary membrane proteins traffic through the Golgi via a
            Rabep1/GGA1/Arl3-dependent mechanism
  JOURNAL   Nat Commun 5, 5482 (2014)
   PUBMED   25405894
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 800)
  AUTHORS   Wright,K.J., Baye,L.M., Olivier-Mason,A., Mukhopadhyay,S., Sang,L.,
            Kwong,M., Wang,W., Pretorius,P.R., Sheffield,V.C., Sengupta,P.,
            Slusarski,D.C. and Jackson,P.K.
  TITLE     An ARL3-UNC119-RP2 GTPase cycle targets myristoylated NPHP3 to the
            primary cilium
  JOURNAL   Genes Dev 25 (22), 2347-2360 (2011)
   PUBMED   22085962
REFERENCE   5  (bases 1 to 800)
  AUTHORS   Lai,C.K., Gupta,N., Wen,X., Rangell,L., Chih,B., Peterson,A.S.,
            Bazan,J.F., Li,L. and Scales,S.J.
  TITLE     Functional characterization of putative cilia genes by high-content
            analysis
  JOURNAL   Mol Biol Cell 22 (7), 1104-1119 (2011)
   PUBMED   21289087
REFERENCE   6  (bases 1 to 800)
  AUTHORS   Zhou,C., Cunningham,L., Marcus,A.I., Li,Y. and Kahn,R.A.
  TITLE     Arl2 and Arl3 regulate different microtubule-dependent processes
  JOURNAL   Mol Biol Cell 17 (5), 2476-2487 (2006)
   PUBMED   16525022
REFERENCE   7  (bases 1 to 800)
  AUTHORS   Hanzal-Bayer,M., Linari,M. and Wittinghofer,A.
  TITLE     Properties of the interaction of Arf-like protein 2 with PDEdelta
  JOURNAL   J Mol Biol 350 (5), 1074-1082 (2005)
   PUBMED   15979089
REFERENCE   8  (bases 1 to 800)
  AUTHORS   Grayson,C., Bartolini,F., Chapple,J.P., Willison,K.R.,
            Bhamidipati,A., Lewis,S.A., Luthert,P.J., Hardcastle,A.J.,
            Cowan,N.J. and Cheetham,M.E.
  TITLE     Localization in the human retina of the X-linked retinitis
            pigmentosa protein RP2, its homologue cofactor C and the RP2
            interacting protein Arl3
  JOURNAL   Hum Mol Genet 11 (24), 3065-3074 (2002)
   PUBMED   12417528
REFERENCE   9  (bases 1 to 800)
  AUTHORS   Linari,M., Hanzal-Bayer,M. and Becker,J.
  TITLE     The delta subunit of rod specific cyclic GMP phosphodiesterase, PDE
            delta, interacts with the Arf-like protein Arl3 in a GTP specific
            manner
  JOURNAL   FEBS Lett 458 (1), 55-59 (1999)
   PUBMED   10518933
REFERENCE   10 (bases 1 to 800)
  AUTHORS   Cavenagh,M.M., Breiner,M., Schurmann,A., Rosenwald,A.G., Terui,T.,
            Zhang,C., Randazzo,P.A., Adams,M., Joost,H.G. and Kahn,R.A.
  TITLE     ADP-ribosylation factor (ARF)-like 3, a new member of the ARF
            family of GTP-binding proteins cloned from human and rat tissues
  JOURNAL   J Biol Chem 269 (29), 18937-18942 (1994)
   PUBMED   8034651
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC084722.1.
            
            On Jun 10, 2007 this sequence version replaced NM_022700.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC084722.1, X76921.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760389
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..800
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q54"
     gene            1..800
                     /gene="Arl3"
                     /note="ARF like GTPase 3"
                     /db_xref="GeneID:64664"
                     /db_xref="RGD:69327"
     exon            1..11
                     /gene="Arl3"
                     /inference="alignment:Splign:2.1.0"
     CDS             9..557
                     /gene="Arl3"
                     /note="ADP ribosylation factor like GTPase 3; ARD3;
                     ADP-ribosylation-like 3; ADP-ribosylation factor-like 3"
                     /codon_start=1
                     /product="ADP-ribosylation factor-like protein 3"
                     /protein_id="NP_073191.1"
                     /db_xref="GeneID:64664"
                     /db_xref="RGD:69327"
                     /translation="MGLLSILRKLKSAPDQEVRILLLGLDNAGKTTLLKQLASEDISH
                     ITPTQGFNIKSVQSQGFKLNVWDIGGQRKIRPYWRSYFENTDILIYVIDSADRKRFEE
                     TGQELTELLEEEKLSCVPVLVFANKQDLLTAAPAAEIAEGLNLHTIRDRVWQIQSCSA
                     LTGEGVQDGMNWVCKNVNAKKK"
     exon            12..155
                     /gene="Arl3"
                     /inference="alignment:Splign:2.1.0"
     exon            156..272
                     /gene="Arl3"
                     /inference="alignment:Splign:2.1.0"
     exon            273..323
                     /gene="Arl3"
                     /inference="alignment:Splign:2.1.0"
     exon            324..509
                     /gene="Arl3"
                     /inference="alignment:Splign:2.1.0"
     exon            510..779
                     /gene="Arl3"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gcttgaggat gggcttgctc tctattttgc gcaaattgaa aagtgcacca gaccaggagg
       61 tgcgaatcct cctcctgggc ttggacaacg ctggcaagac gaccctgctg aagcagcttg
      121 catctgaaga catcagccac atcacaccta cacagggatt taacatcaaa agtgtacagt
      181 cacaaggttt taaactgaat gtatgggaca ttggcggaca gaggaaaatc agaccatact
      241 ggagaagcta ttttgaaaac actgatattc ttatatacgt aattgacagt gcagacagaa
      301 aaagatttga agagacgggt caggagctaa cggaattgct ggaggaagaa aagctgagct
      361 gtgtgccagt gctcgtcttt gctaacaagc aggatctgct cacggcggcc ccagccgcag
      421 agatcgcaga agggctaaac ctacacacca ttcgggaccg cgtctggcag atccagtcct
      481 gctcagcgct cacaggcgag ggcgtccagg acggcatgaa ctgggtctgc aagaatgtca
      541 acgcaaagaa gaagtaagat gccgagggag gcgcggagct gcgggagctg gtcccgccct
      601 gagaaagaaa cactggcttg cgctttctga ccaaaggctt tcccatctgc acggccacag
      661 ctgtgtggtg ggaggggaca gcagcttaag aggaaccccc attccagcag tagattttaa
      721 ctgatctcag aggttcagta tcgtttttca aataaaggaa ttatattgtt tcctctgcaa
      781 aaaaaaaaaa aaaaaaaaaa
//
