LOCUS       NM_031711                876 bp    mRNA    linear   ROD 12-NOV-2024
DEFINITION  Rattus norvegicus ARF like GTPase 2 (Arl2), mRNA.
ACCESSION   NM_031711
VERSION     NM_031711.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 876)
  AUTHORS   Lokaj,M., Kosling,S.K., Koerner,C., Lange,S.M., van Beersum,S.E.,
            van Reeuwijk,J., Roepman,R., Horn,N., Ueffing,M., Boldt,K. and
            Wittinghofer,A.
  TITLE     The Interaction of CCDC104/BARTL1 with Arl3 and Implications for
            Ciliary Function
  JOURNAL   Structure 23 (11), 2122-2132 (2015)
   PUBMED   26455799
REFERENCE   2  (bases 1 to 876)
  AUTHORS   Tian,G., Thomas,S. and Cowan,N.J.
  TITLE     Effect of TBCD and its regulatory interactor Arl2 on tubulin and
            microtubule integrity
  JOURNAL   Cytoskeleton (Hoboken) 67 (11), 706-714 (2010)
   PUBMED   20740604
REFERENCE   3  (bases 1 to 876)
  AUTHORS   Nishi,H., Ono,K., Iwanaga,Y., Horie,T., Nagao,K., Takemura,G.,
            Kinoshita,M., Kuwabara,Y., Mori,R.T., Hasegawa,K., Kita,T. and
            Kimura,T.
  TITLE     MicroRNA-15b modulates cellular ATP levels and degenerates
            mitochondria via Arl2 in neonatal rat cardiac myocytes
  JOURNAL   J Biol Chem 285 (7), 4920-4930 (2010)
   PUBMED   20007690
  REMARK    GeneRIF: The results suggest that miR-15b may decrease
            mitochondrial integrity by targeting Arl2 in the heart.
REFERENCE   4  (bases 1 to 876)
  AUTHORS   Muromoto,R., Sekine,Y., Imoto,S., Ikeda,O., Okayama,T., Sato,N. and
            Matsuda,T.
  TITLE     BART is essential for nuclear retention of STAT3
  JOURNAL   Int Immunol 20 (3), 395-403 (2008)
   PUBMED   18234692
REFERENCE   5  (bases 1 to 876)
  AUTHORS   Yoshimura,S., Egerer,J., Fuchs,E., Haas,A.K. and Barr,F.A.
  TITLE     Functional dissection of Rab GTPases involved in primary cilium
            formation
  JOURNAL   J Cell Biol 178 (3), 363-369 (2007)
   PUBMED   17646400
REFERENCE   6  (bases 1 to 876)
  AUTHORS   Hanzal-Bayer,M., Linari,M. and Wittinghofer,A.
  TITLE     Properties of the interaction of Arf-like protein 2 with PDEdelta
  JOURNAL   J Mol Biol 350 (5), 1074-1082 (2005)
   PUBMED   15979089
REFERENCE   7  (bases 1 to 876)
  AUTHORS   Kobayashi,A., Kubota,S., Mori,N., McLaren,M.J. and Inana,G.
  TITLE     Photoreceptor synaptic protein HRG4 (UNC119) interacts with ARL2
            via a putative conserved domain
  JOURNAL   FEBS Lett 534 (1-3), 26-32 (2003)
   PUBMED   12527357
REFERENCE   8  (bases 1 to 876)
  AUTHORS   Sharer,J.D., Shern,J.F., Van Valkenburgh,H., Wallace,D.C. and
            Kahn,R.A.
  TITLE     ARL2 and BART enter mitochondria and bind the adenine nucleotide
            transporter
  JOURNAL   Mol Biol Cell 13 (1), 71-83 (2002)
   PUBMED   11809823
REFERENCE   9  (bases 1 to 876)
  AUTHORS   Bhamidipati,A., Lewis,S.A. and Cowan,N.J.
  TITLE     ADP ribosylation factor-like protein 2 (Arl2) regulates the
            interaction of tubulin-folding cofactor D with native tubulin
  JOURNAL   J Cell Biol 149 (5), 1087-1096 (2000)
   PUBMED   10831612
REFERENCE   10 (bases 1 to 876)
  AUTHORS   Icard-Liepkalns,C., Ravassard,P., Liepkalns,V.A., Chatail,F. and
            Mallet,J.
  TITLE     An ADP-ribosylation-factor(ARF)-like protein involved in regulated
            secretion
  JOURNAL   Eur J Biochem 246 (2), 388-393 (1997)
   PUBMED   9208929
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from
            JAXUCZ010000001.1.
            
            On Nov 26, 2020 this sequence version replaced NM_031711.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: Y12708.1, DV724320.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA5760400,
                                           SAMEA5760434 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-96                JAXUCZ010000001.1  212875271-212875366 c
            97-207              JAXUCZ010000001.1  212866592-212866702 c
            208-370             JAXUCZ010000001.1  212866340-212866502 c
            371-451             JAXUCZ010000001.1  212864889-212864969 c
            452-876             JAXUCZ010000001.1  212863423-212863847 c
FEATURES             Location/Qualifiers
     source          1..876
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q43"
     gene            1..876
                     /gene="Arl2"
                     /note="ARF like GTPase 2"
                     /db_xref="GeneID:65142"
                     /db_xref="RGD:69326"
     exon            1..96
                     /gene="Arl2"
                     /inference="alignment:Splign:2.1.0"
     CDS             32..586
                     /gene="Arl2"
                     /note="ADP-ribosylation-like 2; ADP-ribosylation factor
                     like GTPase 2; ADP-ribosylation factor-like 2"
                     /codon_start=1
                     /product="ADP-ribosylation factor-like protein 2"
                     /protein_id="NP_113899.2"
                     /db_xref="GeneID:65142"
                     /db_xref="RGD:69326"
                     /translation="MGLLTILKKMKQKERELRLLMLGLDNAGKTTILKKFNGEDVDTI
                     SPTLGFNIKTLEHRGFKLNIWDVGGQKSLRSYWRNYFESTDGLIWVVDSADRQRMQDC
                     QRELQSLLVEERLAGATLLIFANKQDLPGALSCNAIQEALELDSIRSHHWRIQGCSAV
                     TGEDLLPGIDWLLDDISSRVFTAD"
     exon            97..207
                     /gene="Arl2"
                     /inference="alignment:Splign:2.1.0"
     exon            208..370
                     /gene="Arl2"
                     /inference="alignment:Splign:2.1.0"
     exon            371..451
                     /gene="Arl2"
                     /inference="alignment:Splign:2.1.0"
     exon            452..876
                     /gene="Arl2"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gaaacggcgg ccgggagggg gctacgggat catggggctt ctgaccattc tgaagaagat
       61 gaagcagaaa gagcgagagc tgcggctgct catgcttggc ttggacaatg ctggcaaaac
      121 aaccatcctc aagaagttca atggagaaga tgtggacacc atctcgccaa cactgggctt
      181 caacatcaag accctggagc accggggatt caagctgaac atctgggatg tgggtggcca
      241 gaagtctctg cgctcctact ggaggaacta cttcgagagc acagatggcc tcatctgggt
      301 ggtggacagc gctgaccgcc agcgcatgca ggactgtcag cgagagctgc agagtctact
      361 ggtggaggag cgcctggctg gagcgaccct cctcatcttt gccaacaagc aggacctgcc
      421 tggagcactg tcctgtaatg ctattcagga ggccctagag ctggactcca tccgcagcca
      481 ccactggcgc atccaaggct gcagtgccgt cacaggggag gacctgctgc ctggcatcga
      541 ctggctcctc gatgacattt ccagtcgtgt ctttactgcc gactgagctt cttcagtgtc
      601 ccagctcact gtctaggtcc ctgtcctcat ccgacaccag ccggagggat aagcaccagc
      661 tggccagact aacattccca accccaccgt gacctgctgc tgctactgct gcccactgct
      721 gctccctcgg aggagggctg tcacccatct cccaaagtgg cctgcagccg ccatgccaaa
      781 aggaaagact gggctgggag ggactgcctg ctgctgccag gatcctgggt gtcctcctca
      841 cctgtccagc agtgagaata aagtcctcct caccca
//
