LOCUS       NM_001399179            4571 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus AT-rich interaction domain 5A (Arid5a),
            transcript variant 2, mRNA.
ACCESSION   NM_001399179 XM_006244806
VERSION     NM_001399179.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 4571)
  AUTHORS   Zaman,M.M., Masuda,K., Nyati,K.K., Dubey,P.K., Ripley,B., Wang,K.,
            Chalise,J.P., Higa,M., Hanieh,H. and Kishimoto,T.
  TITLE     Arid5a exacerbates IFN-gamma-mediated septic shock by stabilizing
            T-bet mRNA
  JOURNAL   Proc Natl Acad Sci U S A 113 (41), 11543-11548 (2016)
   PUBMED   27671645
REFERENCE   2  (bases 1 to 4571)
  AUTHORS   Masuda,K., Ripley,B., Nyati,K.K., Dubey,P.K., Zaman,M.M.,
            Hanieh,H., Higa,M., Yamashita,K., Standley,D.M., Mashima,T.,
            Katahira,M., Okamoto,T., Matsuura,Y., Takeuchi,O. and Kishimoto,T.
  TITLE     Arid5a regulates naive CD4+ T cell fate through selective
            stabilization of Stat3 mRNA
  JOURNAL   J Exp Med 213 (4), 605-619 (2016)
   PUBMED   27022145
REFERENCE   3  (bases 1 to 4571)
  AUTHORS   Amano,K., Hata,K., Muramatsu,S., Wakabayashi,M., Takigawa,Y.,
            Ono,K., Nakanishi,M., Takashima,R., Kogo,M., Matsuda,A.,
            Nishimura,R. and Yoneda,T.
  TITLE     Arid5a cooperates with Sox9 to stimulate chondrocyte-specific
            transcription
  JOURNAL   Mol Biol Cell 22 (8), 1300-1311 (2011)
   PUBMED   21346191
REFERENCE   4  (bases 1 to 4571)
  AUTHORS   Georgescu,S.P., Li,J.H., Lu,Q., Karas,R.H., Brown,M. and
            Mendelsohn,M.E.
  TITLE     Modulator recognition factor 1, an AT-rich interaction domain
            family member, is a novel corepressor for estrogen receptor alpha
  JOURNAL   Mol Endocrinol 19 (10), 2491-2501 (2005)
   PUBMED   15941852
REFERENCE   5  (bases 1 to 4571)
  AUTHORS   Patsialou,A., Wilsker,D. and Moran,E.
  TITLE     DNA-binding properties of ARID family proteins
  JOURNAL   Nucleic Acids Res 33 (1), 66-80 (2005)
   PUBMED   15640446
  REMARK    Publication Status: Online-Only
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000009.1.
            
            On Jan 4, 2022 this sequence version replaced XM_006244806.4.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643298.48417.1,
                                           SRR26643284.12197.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760386, SAMEA5760393
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-83                JAXUCZ010000009.1  46030579-46030661
            84-202              JAXUCZ010000009.1  46038785-46038903
            203-323             JAXUCZ010000009.1  46039742-46039862
            324-376             JAXUCZ010000009.1  46040143-46040195
            377-474             JAXUCZ010000009.1  46040522-46040619
            475-640             JAXUCZ010000009.1  46040923-46041088
            641-4571            JAXUCZ010000009.1  46041433-46045363
FEATURES             Location/Qualifiers
     source          1..4571
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="9"
                     /map="9q21"
     gene            1..4571
                     /gene="Arid5a"
                     /note="AT-rich interaction domain 5A"
                     /db_xref="GeneID:316327"
                     /db_xref="RGD:1311041"
     exon            1..83
                     /gene="Arid5a"
                     /inference="alignment:Splign:2.1.0"
     CDS             80..1852
                     /gene="Arid5a"
                     /note="isoform 2 is encoded by transcript variant 2;
                     AT-rich interactive domain-containing protein 5A; AT rich
                     interactive domain 5A (Mrf1 like)"
                     /codon_start=1
                     /product="AT-rich interactive domain-containing protein 5A
                     isoform 2"
                     /protein_id="NP_001386108.1"
                     /db_xref="GeneID:316327"
                     /db_xref="RGD:1311041"
                     /translation="MAAPSAKGKAEQSEEGDLQEPPVSPKPQDEQSKSQSPIQLEDSP
                     KAGGEQEEEQAFLVSLYKFMKERHTPIERVPHLGFKQINLWKIYKAVEKLGAYELVTG
                     RRLWKNVYDELGGSPGSTSAATCTRRHYERLVLPYVRHLKGEDDKPLPPTKPRKQYKM
                     AKELRGDDGATEKLKKAKDSEERQADQTTSEKTKSDAPGQTQLPRQGSSRDSTEQLGP
                     VSGSSPPFLGANSCPEAYKRLLASFYCKGAHGIMSPLAKKKLLAQVSKAEALQCQEEG
                     CRHGARSPNKDLQESSQNPRGLAENSEHQLTPPEGLRAPGGSTGVEAQVGPCPTAPTF
                     LGRFHAYPTEVLKPVSQHPRDFFSSLKDRVLLGPPGKEEGLTAKESQLVWGGDANRPS
                     AFHKGSTRKRSFYPKPKACWVSPMAKVPAESPGAPLPHPRSPGLSKKRGLEEEGYTHG
                     GKKLKAVSPFLKEVDARESEGKPAAPGLAVSCLLGPALGPTPPESYRGTMLRCPLNFT
                     SSADPLKGQASLPFSPLVIPTFPAHLLATTGPSPMATSLMHFPPTPYDTVLRNRLGPA
                     SSAWHVPPVTTYAAPHFFHLNTKL"
     exon            84..202
                     /gene="Arid5a"
                     /inference="alignment:Splign:2.1.0"
     exon            203..323
                     /gene="Arid5a"
                     /inference="alignment:Splign:2.1.0"
     exon            324..376
                     /gene="Arid5a"
                     /inference="alignment:Splign:2.1.0"
     exon            377..474
                     /gene="Arid5a"
                     /inference="alignment:Splign:2.1.0"
     exon            475..640
                     /gene="Arid5a"
                     /inference="alignment:Splign:2.1.0"
     exon            641..4571
                     /gene="Arid5a"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 agtcgcgccg agagcgctgg gagcggacgg ctgtgcgcat cgagggtctc cggacggcga
       61 cgcacgctct cgctgggcaa tggcagcacc ttcggctaag gggaaagcgg agcaatcaga
      121 ggaaggtgac ctccaggagc cccctgtgtc ccccaagcct caagatgagc agagcaagag
      181 ccagagcccc atccagcttg aggactcccc taaggcaggt ggggagcagg aggaagaaca
      241 ggccttcctg gtcagcctct acaagttcat gaaggagcga cacacgccca tcgagagggt
      301 gccccatctt ggcttcaagc agattaacct gtggaagatc tacaaggcag tggagaagct
      361 gggggcctat gagctggtga caggccgccg cctctggaag aacgtgtatg atgaacttgg
      421 gggtagcccg ggcagcacca gtgcggctac atgcacacgc cgccactatg agaggctggt
      481 cctcccatat gtgcggcacc tgaagggaga ggacgacaaa ccactgcccc ctaccaagcc
      541 caggaagcaa tacaagatgg ccaaggagct gaggggagat gatggggcca ctgagaagct
      601 gaagaaggcc aaggactcag aggagaggca ggcggaccag accacatcag aaaagaccaa
      661 atcagatgcc cctggccaga cacagcttcc cagacaagga tcctcaaggg atagcacgga
      721 acagctgggc ccagtatctg ggtcttctcc accgttcctg ggtgctaata gctgtcctga
      781 ggcctacaag cggcttttgg cgagcttcta ctgcaaaggg gcgcatggta tcatgtcacc
      841 actggccaaa aagaaactcc tggctcaggt cagcaaggca gaggccttgc agtgccaaga
      901 agagggctgt cgccacggag caaggagccc caacaaggac cttcaagaaa gttcccagaa
      961 cccaagaggg ctggctgaga actctgaaca ccaactaacc cccccggaag gattgcgggc
     1021 ccctggtggc agcactggtg tggaggcaca ggtgggcccc tgccctacag cccccacatt
     1081 cttaggccgt tttcatgcgt accccaccga ggtgctgaag cccgtcagcc agcaccccag
     1141 ggacttcttc tccagcctta aagacagggt gctgttggga ccacctggta aagaggaagg
     1201 gctgacagcc aaagagtccc agctggtatg gggtggggat gccaaccgcc cctctgcatt
     1261 ccacaaaggc agcacaagga aaagaagttt ctatcccaag cccaaagcct gctgggtgtc
     1321 ccccatggcc aaggtccctg ctgagagtcc cggagcccca ctcccccatc ccaggagccc
     1381 aggtcttagc aagaagcgcg gcttggaaga agagggatac actcatggtg gcaagaaact
     1441 gaaggcggtg tctccctttc tgaaggaggt ggatgccagg gagagtgagg gcaagcctgc
     1501 agcccctggc ttggctgtat cctgtctact gggcccagcc ctggggccca ctcctccaga
     1561 gtcctacagg ggcaccatgc tgcggtgtcc tctgaacttc accagtagtg cagaccctct
     1621 gaagggccag gcctcactgc ccttcagccc cctggtcatt cctactttcc cagcccatct
     1681 cctggctaca acaggcccct cgcctatggc taccagcctg atgcatttcc ctcccacgcc
     1741 atatgacact gtccttcgca acagactggg tccagcttcg tctgcctggc acgtgccccc
     1801 cgtcacaacc tatgcggcac cccacttctt ccacctcaac accaaactgt agggcctgag
     1861 tctatcctgc tatgcctcgg agatggggcc tcaaatgggc agatgctgct gcgcatctca
     1921 ggccagacta gcctccccga gtctgactcc ctcgcacaga caggaggagg cagtgggctt
     1981 gtctgaatga agcagcctgt gcccaaagcc cagggaccaa gttgtggtaa gatcatgaaa
     2041 gtacctgagc tggtgttctc tttccacaga ggccaagagg tctgagaggc tggggagcta
     2101 aattatcagc tcaaggcatc caggttggcc acgaaagacc caataaaaag acactggtgt
     2161 gattgcactc agcccaaggg tatacagcat tggacgtttg caaggggagg tgaggcagga
     2221 gcgagcgtgt aggcgtggcc atcagtgtgg gagcaaagat gaaacaaagc cactctggcc
     2281 tggacgctgc caccccactg gagggtaggg ccagagccaa accgggcctc tgtgcgcaga
     2341 tgaacagccg agattccttt cgctccagcc tcaggacact cgactgttga ggttgccgtg
     2401 gtgcaaagcc cagagcacac tggtgacctg tgagacaagt gggaggggct gtgtcattgc
     2461 aaccctctga gctgagccag tcccagaagg ccttgagtct ttcagtgaag ggcttgctct
     2521 gagagacctt gctgtgttgc tcatgttaat ctgggacccc tgacctaaag aaatccaact
     2581 atggccttct cagtagcaga agctacaggt gtgaacctct gtacccgtga agaggggatt
     2641 tgtgggtgtt cgtataaaac ccaagtgagt ctgtcctatt ggtgggcaga cctgtgagcc
     2701 cagctgccta gtgttcccag tcagtaacct gccacatcca cacctatttt tcctgttcca
     2761 catactggac ttggggtgag gggtagaggg aacccatctc tacctgtgaa tctgttgaca
     2821 agtcacagtg atatttaact gtggttgctc caggcgccca cacagaaacc ctgtggcttg
     2881 gcatccacaa ctaccttaga tatggcttgc tctgccagtc ccaaggagac agtacagttt
     2941 cacaccattc ctggaaaggc agggccacca tggcccagag atgctaggat gccagtgaac
     3001 caagtcaaca gatgattact gacctacatc atgggaactc accctctccc tgaccccagg
     3061 ccatgggtag gagggcaagg ttttgtggtc cccttagttc acaggaggca tagccaaggt
     3121 cagcaacagg aagtgccatt gaggatgtct gactctggga aacggtggcc aggaaggcag
     3181 ctgcctgtgg aagggagctg ggacacaggt gtcctccagg accaggtagc cagagggtgg
     3241 aagtcccact gatgcatctt gcaacttccc gccttctgtc tagagatacc aggattccag
     3301 tctgagtatg cagattaaca gccctgagct cctgacaacc cctctgcacc catgcgttag
     3361 cccgtctctg agcttctaca gccccatgag gaaatgccct gggtgttggg ctgcacactg
     3421 tggagtcagg acccaggaga gacagagggt aactttgttt ctggagggat ccccttcatc
     3481 tacaaagtaa cgctagtccg agcctgctca atgatggcat gtggcggaca gcctggaaca
     3541 ggagatcggt ccaagcttca ggagcagagc catctgctgg ttcatcagga gaatgcatgg
     3601 ctgggagggg agggtgtgtt ggtttctggg ccggactcta cctctgcttc agcaaagact
     3661 ctagaaatga atgcaaatca ggcttcctgg gaaacctagg gatattgcac ccatgtgcca
     3721 gtctcacaca atcctccttc cttctgtgaa tgagaaaacc gagctcagag gcgactccaa
     3781 acgccatggt ggctgacagc aggtgcacac accttcccgt gttcacttgt gtccctgaca
     3841 ggttacccca gaggacccac aggactgcag agttctgggc ttgtgtccag ggcataactt
     3901 attgtcagag tctacttcca aatcatttgt gacatctgtg ctaatggtgg gagaaggcag
     3961 aggccaccct ggtatttgtg cagacccaac ccctgcccgt gattccagct catccctgga
     4021 aacagcctaa gtgtgacgag ttggctattc agcaggaaat acctcatttg ccttgggtgt
     4081 aaaagcgtgc tgccccttta actgccttag gtggcgttgg tatacattac accggcatct
     4141 cccacacgag gcaactatca ccaccgcagt tatttgcttg gtttggtttt tcaagacagg
     4201 gtttctctat gcagccctgg ctgccctgga atttactctg tagaccagac tggtctctaa
     4261 ttaatagaga cccacctgcc tctgcctcta cttggattaa agacgtgggc caccatgccc
     4321 agaggccacc tcagccagca accaccagag tattaaatag aatggctgtc aatgttcctt
     4381 ggctactgga ggaacagggc agcaagcctc tgagggagtg gggggagaga gagacagaga
     4441 gaggccagta gccagggggt ctgtggggca gggacagagg aagccagagg tgactcaggc
     4501 tgtatttgga gccttctagt ccaaggggca gttgggcttt tacatgaaat aaaagaaaga
     4561 tgggaagagt g
//
