LOCUS       NM_001419802            8540 bp    mRNA    linear   ROD 09-APR-2024
DEFINITION  Rattus norvegicus AT-rich interaction domain 1B (Arid1b), mRNA.
ACCESSION   NM_001419802 XM_039099685
VERSION     NM_001419802.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 8540)
  AUTHORS   Li,X., Yang,L., Zhang,S. and Shen,J.
  TITLE     The molecular mechanism of the transcriptional activator SWI
            regulating gene ARID1B affecting swallowing dysfunction after
            stroke in rats
  JOURNAL   Pharmazie 76 (10), 494-498 (2021)
   PUBMED   34620277
  REMARK    GeneRIF: The molecular mechanism of the transcriptional activator
            SWI regulating gene ARID1B affecting swallowing dysfunction after
            stroke in rats.
REFERENCE   2  (bases 1 to 8540)
  AUTHORS   Sun,D., Tian,L., Zhu,Y., Wo,Y., Liu,Q., Liu,S., Li,H. and Hou,H.
  TITLE     Subunits of ARID1 serve as novel biomarkers for the sensitivity to
            immune checkpoint inhibitors and prognosis of advanced non-small
            cell lung cancer
  JOURNAL   Mol Med 26 (1), 78 (2020)
   PUBMED   32791957
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 8540)
  AUTHORS   Shibutani,M., Horii,T., Shoji,H., Morita,S., Kimura,M.,
            Terawaki,N., Miyakawa,T. and Hatada,I.
  TITLE     Arid1b Haploinsufficiency Causes Abnormal Brain Gene Expression and
            Autism-Related Behaviors in Mice
  JOURNAL   Int J Mol Sci 18 (9), 1872 (2017)
   PUBMED   28867767
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 8540)
  AUTHORS   Ka,M., Chopra,D.A., Dravid,S.M. and Kim,W.Y.
  TITLE     Essential Roles for ARID1B in Dendritic Arborization and Spine
            Morphology of Developing Pyramidal Neurons
  JOURNAL   J Neurosci 36 (9), 2723-2742 (2016)
   PUBMED   26937011
REFERENCE   5  (bases 1 to 8540)
  AUTHORS   Sim,J.C., White,S.M., Fitzpatrick,E., Wilson,G.R., Gillies,G.,
            Pope,K., Mountford,H.S., Torring,P.M., McKee,S., Vulto-van
            Silfhout,A.T., Jhangiani,S.N., Muzny,D.M., Leventer,R.J.,
            Delatycki,M.B., Amor,D.J. and Lockhart,P.J.
  TITLE     Expanding the phenotypic spectrum of ARID1B-mediated disorders and
            identification of altered cell-cycle dynamics due to ARID1B
            haploinsufficiency
  JOURNAL   Orphanet J Rare Dis 9, 43 (2014)
   PUBMED   24674232
  REMARK    Publication Status: Online-Only
REFERENCE   6  (bases 1 to 8540)
  AUTHORS   Garin,G., Zibara,K., Aguilar,F., Lo,M., Hurlstone,A., Poston,R. and
            Mcgregor,J.L.
  TITLE     6A3-5/Osa2 is an early activated gene implicated in the control of
            vascular smooth muscle cell functions
  JOURNAL   J Biomed Biotechnol 2006 (5), 97287 (2006)
   PUBMED   17489020
REFERENCE   7  (bases 1 to 8540)
  AUTHORS   Florea,L., Di Francesco,V., Miller,J., Turner,R., Yao,A.,
            Harris,M., Walenz,B., Mobarry,C., Merkulov,G.V., Charlab,R.,
            Dew,I., Deng,Z., Istrail,S., Li,P. and Sutton,G.
  TITLE     Gene and alternative splicing annotation with AIR
  JOURNAL   Genome Res 15 (1), 54-66 (2005)
   PUBMED   15632090
REFERENCE   8  (bases 1 to 8540)
  AUTHORS   Garin,G., Badid,C., McGregor,B., Vincent,M., Guerret,S., Zibara,K.,
            Hurlstone,A., Laville,M. and McGregor,J.L.
  TITLE     Ischemia induces early expression of a new transcription factor
            (6A3-5) in kidney vascular smooth muscle cells: studies in rat and
            human renal pathology
  JOURNAL   Am J Pathol 163 (6), 2485-2494 (2003)
   PUBMED   14633620
  REMARK    GeneRIF: 6A3-5 expression is associated with alpha-smooth muscle
            cell actin in mesangial cells, arteriolar smooth muscle cells, and
            interstitial myofibroblasts. could potentially be a novel early
            vascular marker of acute and chronic renal ischemic stress
REFERENCE   9  (bases 1 to 8540)
  AUTHORS   Kato,H., Tjernberg,A., Zhang,W., Krutchinsky,A.N., An,W.,
            Takeuchi,T., Ohtsuki,Y., Sugano,S., de Bruijn,D.R., Chait,B.T. and
            Roeder,R.G.
  TITLE     SYT associates with human SNF/SWI complexes and the C-terminal
            region of its fusion partner SSX1 targets histones
  JOURNAL   J Biol Chem 277 (7), 5498-5505 (2002)
   PUBMED   11734557
  REMARK    Erratum:[J Biol Chem 2002 Apr 19;277(16):14350]
REFERENCE   10 (bases 1 to 8540)
  AUTHORS   Bataini,J.P., Mazabraud,A., Delangre,B. and Ennuyer,A.
  TITLE     [Radiotherapy of bone tumors]
  JOURNAL   Helv Chir Acta 40 (1), 53-68 (1973)
   PUBMED   4633620
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000001.1.
            
            On Apr 19, 2023 this sequence version replaced XM_039099685.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMEA5760383,
                              SAMEA5760386 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            inferred exon combination :: based on alignments, homology
            RefSeq Select criteria    :: based on expression, longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1789              JAXUCZ010000001.1  47973997-47975785
            1790-1984           JAXUCZ010000001.1  48016429-48016623
            1985-2134           JAXUCZ010000001.1  48077573-48077722
            2135-2245           JAXUCZ010000001.1  48108336-48108446
            2246-2489           JAXUCZ010000001.1  48225500-48225743
            2490-2579           JAXUCZ010000001.1  48247578-48247667
            2580-2759           JAXUCZ010000001.1  48264057-48264236
            2760-3087           JAXUCZ010000001.1  48277118-48277445
            3088-3233           JAXUCZ010000001.1  48292170-48292315
            3234-3343           JAXUCZ010000001.1  48297339-48297448
            3344-3502           JAXUCZ010000001.1  48298122-48298280
            3503-3712           JAXUCZ010000001.1  48302798-48303007
            3713-3917           JAXUCZ010000001.1  48305451-48305655
            3918-4056           JAXUCZ010000001.1  48310622-48310760
            4057-4229           JAXUCZ010000001.1  48311001-48311173
            4230-4380           JAXUCZ010000001.1  48316601-48316751
            4381-4477           JAXUCZ010000001.1  48319031-48319127
            4478-5261           JAXUCZ010000001.1  48320729-48321512
            5262-5392           JAXUCZ010000001.1  48323424-48323554
            5393-8540           JAXUCZ010000001.1  48325646-48328793
FEATURES             Location/Qualifiers
     source          1..8540
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q11"
     gene            1..8540
                     /gene="Arid1b"
                     /gene_synonym="6A3-5; smcf-1; Smcf1"
                     /note="AT-rich interaction domain 1B"
                     /db_xref="GeneID:282546"
                     /db_xref="RGD:708504"
     exon            1..1789
                     /gene="Arid1b"
                     /gene_synonym="6A3-5; smcf-1; Smcf1"
                     /inference="alignment:Splign:2.1.0"
     CDS             20..7147
                     /gene="Arid1b"
                     /gene_synonym="6A3-5; smcf-1; Smcf1"
                     /note="transcription factor 1; AT rich interactive domain
                     1B (Swi1 like)"
                     /codon_start=1
                     /product="AT-rich interactive domain-containing protein
                     1B"
                     /protein_id="NP_001406731.1"
                     /db_xref="GeneID:282546"
                     /db_xref="RGD:708504"
                     /translation="MAARSAAAARARAGSCERRAPSGPRPAPGARDLETGARGAVAAA
                     APGPILGGGDGGLNNVHHHPLHPRHDLNMAHSASAAAAASSNSAQSGGSEAALKEGGS
                     AAALSSSAAVAASSSSAGPGSAMETGLLPNHKLKAVGEAPAAPPHQQHHHHHAHHHHH
                     HHAHHLHHHHHALQQQLNQFQQPPQPQQQPPPPPPQQQQHPTANNSLGGAGGGAPQPG
                     PDMEQPQHGGAKDSAAGSQADPQGQPLLSKPGDEDDAPPKMGEPAGSRYEHPGLGAQQ
                     QPAPVAVPGGGGGGPAAVSEFNNYYGSAASASGGPGGRAGPCFDQHGGQQSPGMGMMH
                     SASAAAGAPSSMDPLQNSHEGYPNSQYNHYPGYSRPGAGGGGGGGGGGGGSGGGGGGG
                     GAGGAGGAAAAAAAAGAGAVAAAAAAAAAAAAGGGGGGGYGGSSSGYGVLSSPRQQGG
                     GMMMGPGGGGAASLSKAAAGAAAAAGGFQRFAGQNQHPSGATPTLNQLLTSPSPMMRS
                     YGGSYPDYSSSSAPPPPSQPQSQAAAAAGAAAGGQQAAAGMGLGKDLGAQYAAASPAW
                     AAAQQRNHPAMSPGTPGPTMGRSQGSPMDPMVMKRPQLYGMGTHPHSQPQQSSPYPGG
                     AYGPPGAQRYPLGMQGRAPGALGGLQYPQQQMPPQYGQQGVSGYCQQGQQPYYNQQPQ
                     PSHLPPQAQYLQPQSQQRYQPQQDMSQEGYGTRAQPPLAPGKSNHEDLNLIQQERPSS
                     LPDLSGSIDDLPTGTEATLSSAVSASGSTSSQGDQSNPAQSPFSPHASPHLSSIPGGP
                     SPSPVGSPVGSNQSRSGPISPASIPGSQMPPQPPGSQSESSSHPALSQSPMPQERGFM
                     AGTQRNPQMSQYGPQQTGPSMSPHPSPGGQMHPGISNFQQSNSSGTYGPQMSQYGPQG
                     NYSRTPTYSGVPSASYSGPGPGMGINANNQMHGQGPTQPCGAMPLGRMPSAGMQSRPF
                     PGNMSSVPPSSPGMSQQGGPGMGPPMPTVNRKAQEAAAAVMQAAANSAQSRQGSFPGM
                     NQSGLVASSSPYSQPMNNNSNLMGTQAQPYSMTPTMVNSSTASMGLTDMMSPSESKLS
                     VPLKADGKEEGVPQPESKSKDSYSSQGISQPPTPGNLPVPSPMSPSSASISSFHGDES
                     DSISSPGWPKTPSSPKSSSSSTTGEKITKVYELGTEPERKLWVDRYLTFMEERGSPVS
                     SLPAVGKKPLDLFRLYVCVKEIGGLAQVNKNKKWRELATNLNVGTSSSAASSLKKQYI
                     QYLFAFECKIERGEEPPPEVFSTGDAKKQPKLQPPSPANSGSLQGPQTPQSTGSSSMA
                     EVPGDLKPPTPASTPHGQGTPMQSGRSSTVSVHDPFSDVSDSAYPKRNSMTPNAPYQQ
                     GMGMPDMMGRMPYEPNKDPFSGMRKVPGSSEPFMTQGQMPNSSMQDMYNQSPSGAMSN
                     LGMGQRQQFPYGTSYDRRHEAYGQQYPGQGPPTGQPPYGGHQPGLYPQQPNYKRHMDG
                     MYGPPAKRHEGDMYNMQYGSQQQEMYNQYGGSYSGPDRRPIQGQYPYPYNRERMQGPG
                     QMQPHGIPPQMMGGPMQSSSNEGPQQNMWATRNDMPYPYQNRQGPGGPAQAPPYPGMN
                     RTDDMMVPDQRINHESQWPSHVSQRQPYMSSSASMQPITRPPQSSYQTPPSLPNHISR
                     APSPASFPRSLESRMSPSKSPFLPAMKMQKVMPTVPTSQVTGPPPQPPPIRREITFPP
                     GSVEASQPVLKQRRKITSKDIVTPEAWRVMMSLKSGLLAESTWALDTINILLYDDSTV
                     ATFNLSQLSGFLELLVEYFRKCLIDIFGILMEYEVGDPSQRALDHRTGKKDDSQSSED
                     DSGKEEDDAECLEEEEEEEEEEEEEEEEEEEEEEDSKKTESEGKSSSALAAPDTTADP
                     KETPRQASKFDKLPIKIVKKNNLFVVDRSDRLGRVQEFNSGLLHWQLGGGDTTEHILT
                     HFESKMEIPPRRRPPAPLSSTGKKKELAGKGDSEEQPEKSIIATIDDVLSARPGALPE
                     DSNPGPQTESGKFPFGIQQAKSHRNIRLLEDEPRSRDETPLCTIAHWQDSLAKRCICV
                     SNIVRSLSFVPGNDAEMSKHPGLVLILGKLILLHHEHPERKRAPQTYEKEEDEDKGVA
                     CSKDEWWWDCLEVLRDNTLVTLANISGQLDLSAYTESICLPILDGLLHWMVCPSAEAQ
                     DPFPTVGPNSVLSPQRLVLETLCKLSIQDNNVDLILATPPFSRQEKFYATLVRYVGDR
                     KNPVCREMSMALLSNLAQGDTLAARAIAVQKGSIGNLIGFLEDGVTMAQYQQSQHTLM
                     HMQPPPLEPPSVDMMCRAAKALLAMARVDENRSEFLLHEGRLLDISISAVLNSLVASV
                     ICDVLFQIGQL"
     exon            1790..1984
                     /gene="Arid1b"
                     /gene_synonym="6A3-5; smcf-1; Smcf1"
                     /inference="alignment:Splign:2.1.0"
     exon            1985..2134
                     /gene="Arid1b"
                     /gene_synonym="6A3-5; smcf-1; Smcf1"
                     /inference="alignment:Splign:2.1.0"
     exon            2135..2245
                     /gene="Arid1b"
                     /gene_synonym="6A3-5; smcf-1; Smcf1"
                     /inference="alignment:Splign:2.1.0"
     exon            2246..2489
                     /gene="Arid1b"
                     /gene_synonym="6A3-5; smcf-1; Smcf1"
                     /inference="alignment:Splign:2.1.0"
     exon            2490..2579
                     /gene="Arid1b"
                     /gene_synonym="6A3-5; smcf-1; Smcf1"
                     /inference="alignment:Splign:2.1.0"
     exon            2580..2759
                     /gene="Arid1b"
                     /gene_synonym="6A3-5; smcf-1; Smcf1"
                     /inference="alignment:Splign:2.1.0"
     exon            2760..3087
                     /gene="Arid1b"
                     /gene_synonym="6A3-5; smcf-1; Smcf1"
                     /inference="alignment:Splign:2.1.0"
     exon            3088..3233
                     /gene="Arid1b"
                     /gene_synonym="6A3-5; smcf-1; Smcf1"
                     /inference="alignment:Splign:2.1.0"
     exon            3234..3343
                     /gene="Arid1b"
                     /gene_synonym="6A3-5; smcf-1; Smcf1"
                     /inference="alignment:Splign:2.1.0"
     exon            3344..3502
                     /gene="Arid1b"
                     /gene_synonym="6A3-5; smcf-1; Smcf1"
                     /inference="alignment:Splign:2.1.0"
     exon            3503..3712
                     /gene="Arid1b"
                     /gene_synonym="6A3-5; smcf-1; Smcf1"
                     /inference="alignment:Splign:2.1.0"
     exon            3713..3917
                     /gene="Arid1b"
                     /gene_synonym="6A3-5; smcf-1; Smcf1"
                     /inference="alignment:Splign:2.1.0"
     exon            3918..4056
                     /gene="Arid1b"
                     /gene_synonym="6A3-5; smcf-1; Smcf1"
                     /inference="alignment:Splign:2.1.0"
     exon            4057..4229
                     /gene="Arid1b"
                     /gene_synonym="6A3-5; smcf-1; Smcf1"
                     /inference="alignment:Splign:2.1.0"
     exon            4230..4380
                     /gene="Arid1b"
                     /gene_synonym="6A3-5; smcf-1; Smcf1"
                     /inference="alignment:Splign:2.1.0"
     exon            4381..4477
                     /gene="Arid1b"
                     /gene_synonym="6A3-5; smcf-1; Smcf1"
                     /inference="alignment:Splign:2.1.0"
     exon            4478..5261
                     /gene="Arid1b"
                     /gene_synonym="6A3-5; smcf-1; Smcf1"
                     /inference="alignment:Splign:2.1.0"
     exon            5262..5392
                     /gene="Arid1b"
                     /gene_synonym="6A3-5; smcf-1; Smcf1"
                     /inference="alignment:Splign:2.1.0"
     exon            5393..8540
                     /gene="Arid1b"
                     /gene_synonym="6A3-5; smcf-1; Smcf1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gcgccacgcc gcggcgatca tggccgcgcg gtcagcagcg gcggcgcggg cacgggcggg
       61 cagctgcgag aggcgggcgc cctcggggcc gcggccggcg cccggggccc gggacctgga
      121 gacgggcgcg cgcggcgcgg tggcggcggc ggctccgggc cccatactgg ggggcggcga
      181 cggcggcctg aataatgtgc accaccaccc cctgcacccc cgtcacgacc tgaacatggc
      241 ccatagcgcg agcgccgcgg cggccgccag ctccaacagc gcgcagagcg gcggctccga
      301 ggcggctctc aaggagggtg gaagcgccgc cgcgctgtcc tcctccgccg ccgtcgcggc
      361 ctcttcctcc tcggcgggcc ccggctcggc catggagacc gggctgctcc ccaaccacaa
      421 actgaaagcc gttggcgagg cccccgctgc accgccccat cagcagcacc accaccacca
      481 tgcccaccac caccatcacc accatgccca ccacctccac caccaccacc acgcactaca
      541 gcagcagcta aaccagttcc agcagccgcc gcagccacag cagcagccgc cgccgccgcc
      601 gccgcagcag cagcagcatc ccactgccaa caacagcctg ggcggtgcgg gcggcggcgc
      661 gcctcagccc ggcccggaca tggagcagcc gcaacatgga ggcgccaagg acagtgccgc
      721 gggcagtcag gctgacccgc agggccagcc tctgctgagc aagccgggcg acgaggacga
      781 cgcgccgccc aagatggggg agccggcggg cagccgctat gagcacccag gcctgggcgc
      841 gcagcaacag cccgcgccgg tcgccgtgcc cgggggcggc ggcggcggcc cggcggccgt
      901 ctcggagttt aataattact atggcagcgc tgcctctgct agcggcggcc ccggcggccg
      961 cgctgggcct tgctttgatc aacatggcgg acaacaaagc cccgggatgg ggatgatgca
     1021 ctccgcctct gccgccgccg gggcccccag cagcatggac cccctgcaga actcccacga
     1081 agggtacccc aacagccagt acaaccatta tccgggctac agccggcccg gcgcgggcgg
     1141 cggcggcggc ggaggaggag gaggaggagg cagcggagga ggtggaggag gaggaggagc
     1201 aggaggagca ggaggagcag cggcagcggc agcggcagca ggagccggag ctgtggcggc
     1261 ggcggccgcg gcggcggcag cagcagcagc aggaggaggc ggtggcggcg gctatggggg
     1321 ctcgtcctcg gggtacgggg tgctgagctc cccgcggcag cagggcggcg gcatgatgat
     1381 gggccccggg ggcggcgggg ccgcgagcct cagcaaggcg gccgccggtg cggcggcggc
     1441 ggcggggggc ttccagcgct tcgccggcca gaaccagcac ccgtcggggg ccacgccgac
     1501 cctcaaccag ctgctcacct cgcccagccc catgatgcgg agctacggcg gtagctaccc
     1561 cgactacagc agctccagcg cgccgccgcc gccgtcgcag ccccagtccc aggcggcggc
     1621 ggcggcgggg gcggcggcgg gtggccagca ggcggccgcg ggcatgggct tgggcaagga
     1681 cctaggcgcc cagtacgccg ctgccagccc ggcctgggcg gccgcgcaac aaaggaatca
     1741 cccggcgatg agccccggca cccctggacc gaccatgggc agatcccagg gcagtccgat
     1801 ggacccaatg gtgatgaaga gacctcagtt gtatgggatg ggcactcacc cccattcgca
     1861 gccgcagcag agcagcccat acccaggagg tgcctacggc cccccaggcg cacagcggta
     1921 tccccttggc atgcagggcc gggctccagg ggccctggga ggcttgcagt acccacagca
     1981 gcagatgcca ccgcagtatg gacagcaagg tgtgagtggt tactgccagc aaggccagca
     2041 gccatattac aaccagcagc cacagccctc gcacctcccg ccccaggcac agtacctaca
     2101 gccacagtcc cagcagaggt accagccaca gcaggacatg tctcaggaag gctatggaac
     2161 tagagctcag cctcctctgg cccctggaaa atccaaccac gaagacttga atttaataca
     2221 acaggaaaga ccatcgagtc taccagacct gtctggctcc atcgatgatc tccccacggg
     2281 aacagaagca actctgagct cagcggtcag tgcgtccggg tctacgagca gccaggggga
     2341 tcagagcaac ccagctcagt ctcctttctc cccacatgca tcaccccacc tctccagcat
     2401 ccccggaggg ccgtcacctt ctcctgttgg ctctcctgtg ggcagcaacc agtcgaggtc
     2461 tggcccaatc tcccctgcga gtataccagg cagccagatg cctccgcagc cacctggaag
     2521 ccagtcagaa tccagttccc accctgcctt gagccagtcc ccaatgccac aggagagagg
     2581 ttttatggca ggcacacaga gaaaccctca gatgtctcag tacggacctc agcagacagg
     2641 accatccatg tcacctcacc cttctcctgg gggccagatg catcctggaa tcagtaactt
     2701 tcagcagagt aactcaagtg gcacgtatgg tccacagatg agccagtatg gaccccaagg
     2761 caactactcc agaaccccaa catatagcgg ggtgcccagt gcaagctaca gcggcccagg
     2821 gcctggtatg ggcatcaatg ccaacaacca gatgcatgga caagggccaa cccagccatg
     2881 tggtgctatg cccctgggac gaatgccatc agctgggatg cagagcagac cttttcctgg
     2941 aaacatgagc agcgtccccc ccagctctcc tggcatgtct caacagggag ggccaggaat
     3001 gggcccacca atgcccactg tgaaccgcaa ggcccaggaa gctgccgcgg ctgtgatgca
     3061 ggctgctgca aactcagccc aaagcaggca aggcagcttt cctggcatga accagagtgg
     3121 actcgtggcc tccagctctc cctacagcca gcccatgaac aataactcca acctaatggg
     3181 cacacaggcc cagccctaca gcatgacacc caccatggtg aacagctcta cagcatctat
     3241 gggtcttaca gatatgatgt ctcccagtga gtccaaactg tccgtgcctc ttaaagcaga
     3301 tggcaaagaa gaaggtgtgc cccagcctga gagcaagtca aaggatagct acagctctca
     3361 gggtatttct cagcctccaa ctccaggcaa cctgccagtc ccttccccaa tgtcccccag
     3421 ctctgccagc atctcctcct ttcacggaga tgagagtgat agcattagca gcccaggctg
     3481 gcccaagact ccatcaagcc ctaagtccag ctcctcttcc accactgggg agaagatcac
     3541 aaaagtgtat gagctgggga ctgagccgga gaggaagctg tgggtcgacc gctacctgac
     3601 attcatggag gagagggggt cccccgtgtc cagtctgccg gcagtgggca agaagcccct
     3661 ggacctgttc cgactctatg tgtgcgtcaa agagatcgga ggcttggcgc aggttaataa
     3721 aaacaagaag tggcgtgagc tggcaaccaa cctgaacgtt ggcacttcga gcagcgcagc
     3781 cagctccctg aagaagcaat atattcagta cctgttcgcc ttcgagtgca aaattgagcg
     3841 tggggaggag cccccgcctg aagtcttcag cacgggggat gcgaagaagc agcccaagct
     3901 ccagccgcca tctcctgcta actcgggatc cttacaaggt ccacagacgc cacagtcaac
     3961 tggcagcagt tccatggcag aggttcccgg tgacctgaag ccaccaaccc cagcctccac
     4021 ccctcacgga caggggaccc ccatgcaaag cggaagaagc agtacagtca gtgtgcatga
     4081 cccgttctca gacgtgagtg attcagcgta cccaaaacgg aactccatga ctccaaacgc
     4141 cccataccag cagggcatgg gcatgccaga catgatgggc aggatgccct atgagcccaa
     4201 caaggaccct ttcagtggaa tgagaaaagt gcctggaagc agcgagccct ttatgacaca
     4261 aggacagatg cccaacagca gtatgcagga catgtacaac cagagtccct caggtgccat
     4321 gtccaatctg ggcatgggac agcggcagca atttccctat ggaaccagtt atgaccgaag
     4381 gcatgaggct tacgggcagc agtacccagg ccaaggccct cccacaggac agccaccgta
     4441 tggaggacac cagcctggcc tgtacccaca gcagccgaat tacaaacgcc atatggatgg
     4501 catgtacggg cctccagcca agcgccacga gggagacatg tacaacatgc agtatggcag
     4561 ccaacagcag gagatgtata accagtacgg aggctcctac tctggcccgg acagaaggcc
     4621 catccaggga cagtatccct acccctacaa tagagaaagg atgcagggcc caggccagat
     4681 gcagccacat ggaatcccac ctcagatgat gggtggcccc atgcagtcat cttccaatga
     4741 ggggcctcag cagaatatgt gggctacacg caatgatatg ccttatccct accagaacag
     4801 gcaaggccca ggtggccctg cacaggcacc cccttaccca ggcatgaacc gcacagatga
     4861 tatgatggta cctgatcaga ggatcaatca cgagagccag tggccttctc atgtcagcca
     4921 gcgccagcct tatatgtcat catcggcctc catgcaaccc atcacgcgcc cacctcagtc
     4981 atcctaccag acgccgccgt cactgccaaa ccacatctcc agggcaccca gccctgcctc
     5041 cttcccgcgc tccctggaga gccgcatgtc tccaagcaag tcccccttcc tgcctgccat
     5101 gaagatgcag aaggtcatgc ccacggtccc cacatcccag gtcaccggac cacccccaca
     5161 gccaccgcca atcagaaggg agattacctt tcctcctggc tcagtagaag catcgcagcc
     5221 agtcctgaaa caaaggcgga agattacctc aaaagatatt gttactcccg aggcgtggcg
     5281 tgtgatgatg tcccttaaat ccggtctgtt ggctgagagc acgtgggctt tggacaccat
     5341 caacattctc ctctatgatg acagcactgt cgccaccttc aatctttccc agctgtcggg
     5401 gttcctggaa ctactagtgg agtacttccg aaagtgccta attgacattt tcggtattct
     5461 gatggaatat gaagtgggtg accccagcca aagggcgctt gatcaccgca cagggaagaa
     5521 agacgacagc cagtcctcgg aggacgactc tgggaaagaa gaagatgatg ccgagtgtct
     5581 ggaggaggag gaggaggagg aggaggaaga ggaggaggag gaagaggagg aggaggaaga
     5641 ggaggaagac agtaaaaaga cagagtcaga gggcaagagc agctctgccc tagctgctcc
     5701 agacaccact gcggacccca aggagacgcc gaggcaggcc agtaagtttg acaagctgcc
     5761 cataaagatt gtcaagaaga acaacctgtt tgtggtggac cggtccgaca ggctgggtcg
     5821 ggttcaagag ttcaacagcg ggctcctcca ctggcagctg ggtggtggcg acaccactga
     5881 gcacatcctc actcacttcg agagcaagat ggagatccct cctcgcaggc gtccacctgc
     5941 gcctctcagc tccacgggta agaagaaaga gctggcaggc aagggcgatt ctgaagagca
     6001 gccagagaaa agcatcatag ccaccattga tgatgtcctg tctgcccgac caggggccct
     6061 gccggaagac agcaaccccg gaccccaaac cgagagcggc aagtttccct ttggaatcca
     6121 gcaggccaaa agccaccgga acatcaggct cctggaggac gagcccagga gccgagacga
     6181 gactcccctg tgcaccattg cgcactggca ggactccctg gccaaacgct gcatctgtgt
     6241 gtctaacatc gtgcggagct tgtctttcgt gcctggcaac gacgcagaga tgtccaaaca
     6301 tccgggcttg gtgctgatcc taggaaagtt gattctgctg catcatgagc atccggagag
     6361 aaaacgggcg ccacagacct atgagaagga ggaggatgag gacaaggggg tggcctgcag
     6421 caaagatgag tggtggtggg actgcctcga ggtcttgcgg gataacacac tggtcacatt
     6481 ggctaacatt tccgggcagc tagacttgtc tgcttacaca gagagcatct gcttgccgat
     6541 cctggacggc ttgctgcact ggatggtgtg cccgtctgca gaggcacagg acccctttcc
     6601 cactgtgggg cccaactcag ttctatcgcc acaaagactt gtgctggaga cactgtgtaa
     6661 actcagtatc caggacaaca atgtggacct gatcttggcc acacctccat ttagtcgtca
     6721 ggagaaattt tatgctacat tagttaggta cgttggggat cgcaaaaacc cagtctgccg
     6781 agaaatgtcc atggcgcttt tatcgaacct tgcccagggg gatacactgg cagcgagggc
     6841 aatagctgtg cagaaaggaa gcattgggaa cttgataggc ttcctggagg acggggtcac
     6901 gatggcgcag tatcagcaga gccagcatac cctcatgcac atgcagcccc cgcctctgga
     6961 accccccagt gtggacatga tgtgcagggc ggccaaagct ttgctggcta tggctagagt
     7021 ggatgagaac cgctcggagt tccttttgca cgagggtcgg ttgctggata tctcgatatc
     7081 cgctgtcctg aactctctgg ttgcgtctgt catctgtgat gtactgtttc agattgggca
     7141 gttatgacac ccgtgagggc acacatgtgt gagggaacat tagagggtca catatgactg
     7201 gctgttttct gttctcgttt atccaatgta ggaagaagga aaagaaaaat ctttgcttct
     7261 ctgccccatt cactatttac caattgggaa ttaaagaaat cattaatttg aacagttata
     7321 aattaatatt tgctgtctgt gtgtataagt acatccgttg ggggatttct gtttctttct
     7381 ctttttttta accaaagttg ccgtctagtt cattcacagg tcacatgttt ttttgttttt
     7441 ttcataattt ttttcatgtt gtattacagt tttagggaag tgaattcact ttataaagta
     7501 aaaaggtttg gcaaaaaatg ctgataggaa aatttcacca cactgagtca aaaaggtgaa
     7561 aggaaaaatt gatccttaaa ttgatttcct atgaatttta ttcttcgcag aatgaaaaaa
     7621 gcgaaagtgc atcccattgc ccaaagctct gtgcaataga aacttctaga gatgtaggtg
     7681 taggggctcg aggtatggca gtcagcagtc tggcccagtg atgctgttct ctccacagga
     7741 aagcggttgc attaggcctc gagcaaaaaa ccgcactctc agttaggggc gaaaatccac
     7801 tcctaaccgc caacagcagg attgcttcct caccacgacc gccatgtctg ctgcgactca
     7861 gcctccacct cacagatctt cgtgattcct ttcatcattt tttaaatatt ttttttttac
     7921 tgcctatggg ctgtgatgta tatagaagtt gtacattaaa cataccctca tatttttttc
     7981 ttttcttttt ttttttttag tacaaagttt ttagtttctt tttcatgatg tggtaactac
     8041 gaagtgatgg tagatttaaa taatttttta tttttatttt atatattttt tcattaggac
     8101 catatctcca aaaaacaaga aaaagaaaca aaaaatacaa aaaataaaaa caaacaaaaa
     8161 aagggggtaa tgtacaagtt tctgtatgta taaagtcatg ctctgttggg agggcagctg
     8221 gtcccagttt gcttcatgaa tcaaggtgtg gaaatggttg catacggatt gatttagaaa
     8281 atgaatacca gtacatacaa aaaaaaagaa aaaagaaaaa ccaactaaat gaagaaacac
     8341 aacttcaaag atttttctgt gacaagaatc cgcatttgta tttcaagata atgtagttta
     8401 agaaaagaaa aaagaaaaaa aaaagaaaaa aacttgatgt aaattcctcc ttttcctctg
     8461 gcttaatgaa tatcatttat tcagtataaa atctttatat gtcccacatg ttaagaataa
     8521 atgtacatta aatcttgtta
//
