LOCUS       NM_001271313            6118 bp    mRNA    linear   ROD 27-MAR-2024
DEFINITION  Rattus norvegicus Rho guanine nucleotide exchange factor 40
            (Arhgef40), mRNA.
ACCESSION   NM_001271313 XM_001075554 XM_003751460 XM_003751461 XM_341309
VERSION     NM_001271313.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000015.1.
            
            On or before Sep 16, 2012 this sequence version replaced
            XM_341309.5, XM_003751460.1, XM_003751461.1, XM_001075554.3.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643285.40070.1,
                                           SRR26643290.45942.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760386
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-149               JAXUCZ010000015.1  27146268-27146416
            150-347             JAXUCZ010000015.1  27148904-27149101
            348-1317            JAXUCZ010000015.1  27149690-27150659
            1318-1581           JAXUCZ010000015.1  27150660-27150923
            1582-1749           JAXUCZ010000015.1  27151007-27151174
            1750-1876           JAXUCZ010000015.1  27151945-27152071
            1877-1973           JAXUCZ010000015.1  27153954-27154050
            1974-2054           JAXUCZ010000015.1  27154163-27154243
            2055-2171           JAXUCZ010000015.1  27154354-27154470
            2172-2267           JAXUCZ010000015.1  27156825-27156920
            2268-2383           JAXUCZ010000015.1  27157009-27157124
            2384-2510           JAXUCZ010000015.1  27157467-27157593
            2511-2633           JAXUCZ010000015.1  27158563-27158685
            2634-2777           JAXUCZ010000015.1  27158763-27158906
            2778-3388           JAXUCZ010000015.1  27159653-27160263
            3389-3623           JAXUCZ010000015.1  27160379-27160613
            3624-3710           JAXUCZ010000015.1  27160904-27160990
            3711-3926           JAXUCZ010000015.1  27162955-27163170
            3927-4097           JAXUCZ010000015.1  27164096-27164266
            4098-4275           JAXUCZ010000015.1  27165417-27165594
            4276-4380           JAXUCZ010000015.1  27166911-27167015
            4381-4524           JAXUCZ010000015.1  27167212-27167355
            4525-4655           JAXUCZ010000015.1  27167845-27167975
            4656-4702           JAXUCZ010000015.1  27168242-27168288
            4703-6118           JAXUCZ010000015.1  27168597-27170012
FEATURES             Location/Qualifiers
     source          1..6118
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="15"
                     /map="15p14"
     gene            1..6118
                     /gene="Arhgef40"
                     /gene_synonym="RGD1308093"
                     /note="Rho guanine nucleotide exchange factor 40"
                     /db_xref="GeneID:361034"
                     /db_xref="RGD:1308093"
     exon            1..149
                     /gene="Arhgef40"
                     /gene_synonym="RGD1308093"
                     /inference="alignment:Splign:2.1.0"
     CDS             147..4697
                     /gene="Arhgef40"
                     /gene_synonym="RGD1308093"
                     /note="Rho guanine nucleotide exchange factor (GEF) 40"
                     /codon_start=1
                     /product="rho guanine nucleotide exchange factor 40"
                     /protein_id="NP_001258242.1"
                     /db_xref="GeneID:361034"
                     /db_xref="RGD:1308093"
                     /translation="MEPEPVEDCVQSTLAALYPPFEATAPTLLGQVFQVVERTYQEDA
                     LRYTLDFLVPAKHLLAKVQQEACAQYSGFLFFHEGWPLCLHEQVVVQLAALPWQLLRP
                     GDFYLQVVPSAAQAPRLALKCLAPGGGRVQELPVPNEACAYLFTPEWLQGINKDRPTG
                     RLSTCLLSAPSGIQRLPWAELVCPRFVHKEGLMVGHQPSTLPPELPSGPPGLPSSPLP
                     EEVLGTRSPGDGHNAPAEGPEGEYVELLEVTLPVRGSPIDAEASGLSRTRTVPARKTT
                     GGKGRHRRHRAWMNQKGPGSRDQDGTRPPGEGSSTGASSDSPSGAEADPDAAVLEAPE
                     PPAEASGEASESCLLSGEAVGGVGQGTEGPPDTPRRTGKGNRRKKRAAGRGAVSRGGE
                     STPLSPRDKEETRQPEVLSLPSPSEQEPVECSLVKEKEDSGKPESESKEELKPADEKE
                     PAPPEDYEPPEEGNRESEKEELPPECTAGSTGPEWFPSEPPTQPLETVQDVKEDSIPE
                     ETPPVSASDDPLIVWDLMSSGFFILTGGVDQTGRALLRITPPPPCLPEEPSPSQETLS
                     TALRYLHSLLRPDLQLLGLTILLDLRKVPPLPPALLPALSQLQDSGDPPFIQRLLILT
                     HEDPPEELCGFQGAELLSEKDLKRVAKPEELQWDLGGHRDLSPNHWAEIHQEVARLCT
                     LCQGVLTSVRQAIEELEGAAESKEEESVGMPEPLQKVLADPRLTALQRNGGAILMRLR
                     STHSSKLEGPGPAVLYQEVDEAIHQLVRLSNLRVQQQEQRQRLRQVQEVLQWLSGPGE
                     EQLASFTIPGNSLSVLQETELRFRAFSTEVQERLVQAREALALEEDITSQKVLDIFEQ
                     RLEQVESGLHRALRLQRFFQQAHEWVDEGCARLAGAGPGREAVLAALALRRAPEPSAG
                     TFQEMRALALDLGSPAALREWGRCRARCQELERRIQQQLGEEASPRSHRRRRADSASS
                     AGAQHGAHSPSPSLSSLLLPSSPGPRAAPSHCSLTPCGEDYEEEGLELAPEADGRPPR
                     AVLIRGLEVTSTEVVDRTCSPREHVLLGRAGGPDGPWGIGTPRMERKRSISAQQRLVS
                     ELIDCEQEYITTLNEPVPPPGPELTPGLRCTWAAALSVRERLRSFHGTHFLQELQGCT
                     AHPLRIGACFLRHGDQFNLYAQFVKHRHKLESGLTALTPSVKGSMEGSPCLPRALQQP
                     LEQLARYAQLLEELLREAGPELSSERQALRAAVQLLQEQEARGRDLLAVEAVRGCEID
                     LREQGQLLHRDPFTVICGRKKCLRHVFLFEDLLLFSKSKGSEGGSETFVYKQAFKTAD
                     MGLTENIGDSGLCFELWFRRRRAREAYTLQATSPETKLKWTSSIAQLLWRQAAHNKEL
                     RVQQMVSMGIGNKPFLDIKALGERTLSALLTGRAARTRASVAVSSFEHAGPSLPGLSP
                     GACSLPARVEEEAWDLDVKQISLASETLDSSGDVSPGPRNSPSLQSPNPGSSTPALSS
                     GGILGLSRQSHSRALSDPTTPL"
     exon            150..347
                     /gene="Arhgef40"
                     /gene_synonym="RGD1308093"
                     /inference="alignment:Splign:2.1.0"
     exon            348..1581
                     /gene="Arhgef40"
                     /gene_synonym="RGD1308093"
                     /inference="alignment:Splign:2.1.0"
     exon            1582..1749
                     /gene="Arhgef40"
                     /gene_synonym="RGD1308093"
                     /inference="alignment:Splign:2.1.0"
     exon            1750..1876
                     /gene="Arhgef40"
                     /gene_synonym="RGD1308093"
                     /inference="alignment:Splign:2.1.0"
     exon            1877..1973
                     /gene="Arhgef40"
                     /gene_synonym="RGD1308093"
                     /inference="alignment:Splign:2.1.0"
     exon            1974..2054
                     /gene="Arhgef40"
                     /gene_synonym="RGD1308093"
                     /inference="alignment:Splign:2.1.0"
     exon            2055..2171
                     /gene="Arhgef40"
                     /gene_synonym="RGD1308093"
                     /inference="alignment:Splign:2.1.0"
     exon            2172..2267
                     /gene="Arhgef40"
                     /gene_synonym="RGD1308093"
                     /inference="alignment:Splign:2.1.0"
     exon            2268..2383
                     /gene="Arhgef40"
                     /gene_synonym="RGD1308093"
                     /inference="alignment:Splign:2.1.0"
     exon            2384..2510
                     /gene="Arhgef40"
                     /gene_synonym="RGD1308093"
                     /inference="alignment:Splign:2.1.0"
     exon            2511..2633
                     /gene="Arhgef40"
                     /gene_synonym="RGD1308093"
                     /inference="alignment:Splign:2.1.0"
     exon            2634..2777
                     /gene="Arhgef40"
                     /gene_synonym="RGD1308093"
                     /inference="alignment:Splign:2.1.0"
     exon            2778..3388
                     /gene="Arhgef40"
                     /gene_synonym="RGD1308093"
                     /inference="alignment:Splign:2.1.0"
     exon            3389..3623
                     /gene="Arhgef40"
                     /gene_synonym="RGD1308093"
                     /inference="alignment:Splign:2.1.0"
     exon            3624..3710
                     /gene="Arhgef40"
                     /gene_synonym="RGD1308093"
                     /inference="alignment:Splign:2.1.0"
     exon            3711..3926
                     /gene="Arhgef40"
                     /gene_synonym="RGD1308093"
                     /inference="alignment:Splign:2.1.0"
     exon            3927..4097
                     /gene="Arhgef40"
                     /gene_synonym="RGD1308093"
                     /inference="alignment:Splign:2.1.0"
     exon            4098..4275
                     /gene="Arhgef40"
                     /gene_synonym="RGD1308093"
                     /inference="alignment:Splign:2.1.0"
     exon            4276..4380
                     /gene="Arhgef40"
                     /gene_synonym="RGD1308093"
                     /inference="alignment:Splign:2.1.0"
     exon            4381..4524
                     /gene="Arhgef40"
                     /gene_synonym="RGD1308093"
                     /inference="alignment:Splign:2.1.0"
     exon            4525..4655
                     /gene="Arhgef40"
                     /gene_synonym="RGD1308093"
                     /inference="alignment:Splign:2.1.0"
     exon            4656..4702
                     /gene="Arhgef40"
                     /gene_synonym="RGD1308093"
                     /inference="alignment:Splign:2.1.0"
     exon            4703..6118
                     /gene="Arhgef40"
                     /gene_synonym="RGD1308093"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gcctgggctc cggagcgagc tgggagagcc gcggtcgcag cgcgagctgt cctgcagcta
       61 gacccggcga gactgagcgc ccggagggag gcggtggctc acccgccccg cccgcccaag
      121 agtgggacac ctcccgacgc cgagccatgg agcctgaacc agtggaggac tgtgtgcaga
      181 gcacgctcgc tgccttgtac ccaccctttg aagccacagc cccaaccctg ttgggccagg
      241 tgttccaggt ggtggagagg acatatcagg aggatgcgct gaggtacacg ctggacttcc
      301 tggtacccgc taaacacctg cttgccaagg tccagcagga agcctgtgcc cagtatagtg
      361 gattcctctt cttccacgag ggctggccac tctgcttgca cgagcaagtg gtggtgcagc
      421 tagcggccct tccctggcag ctgctgcgtc ccggagactt ctacctgcag gtagtgcctt
      481 ctgcagccca agcaccccgt ctggcactga aatgtctggc gccaggaggt gggcgggtac
      541 aggagctccc agtgcccaat gaagcctgtg cctacctatt cacacccgag tggctacaag
      601 gcattaacaa ggaccggcca acagggcgtc tcagcacctg ccttctgtct gcaccctctg
      661 gaattcagcg gctaccctgg gctgagctcg tctgcccaag atttgtgcac aaagagggcc
      721 tcatggtggg acatcagcca agcacattgc ctccagaact gccctctgga cctccggggc
      781 ttcctagctc tccactccct gaggaggtac ttggtacccg gagtcctggg gatggacaca
      841 atgctcctgc agaaggtcca gaaggtgaat acgtcgagct gttggaagtg acgctgcctg
      901 tgaggggaag ccccatagat gctgaggcct caggcctctc caggactcgc acagtaccgg
      961 ctcgtaagac cactggaggg aagggtaggc accggagaca cagggcatgg atgaatcaga
     1021 aaggcccggg gtctcgggat caggatggga cacgcccacc tggtgagggt agtagcaccg
     1081 gagcctcttc ggactcccct tcaggggctg aggcagaccc agatgcagca gtcctcgagg
     1141 cacctgagcc cccggcagag gcttcaggag aagcctctga atcctgcctt ctgtcagggg
     1201 aggctgtggg aggagtgggc caggggactg aaggaccacc tgatacccct cgaagaaccg
     1261 gcaaaggaaa cagaaggaag aagcgagctg cgggcagagg tgctgtaagt cggggagggg
     1321 agagtacccc actcagcccc cgggacaaag aagagactag acagccggaa gtccttagtc
     1381 tgccctcacc cagtgaacag gaacctgtag aatgcagcct ggttaaggag aaagaggatt
     1441 ctgggaagcc agagtctgaa tcaaaagagg aactcaagcc agcagatgaa aaagagcctg
     1501 cacccccaga agactatgag cctccagaag aggggaatag agagagtgag aaagaggagt
     1561 tgcccccgga gtgtacggca ggatccacag gtcctgaatg gttcccatct gagcctccaa
     1621 cacagcccct ggagactgtg caggacgtaa aagaagacag catcccagaa gaaactcccc
     1681 cagtttctgc ttcggatgac ccacttatag tttgggactt gatgtcatct ggattcttca
     1741 ttttgactgg aggggtagat cagactggga gagctctgct gaggattacg cctccacctc
     1801 catgccttcc tgaggagccc tcaccctccc aagagacact gagcactgct cttcgctatc
     1861 tccactcact gcttaggcct gatctgcaat tattggggct gaccatcctc cttgaccttc
     1921 gcaaggtgcc cccactgcct ccagcacttc ttcctgcctt gagtcagctt caggactcag
     1981 gcgaccctcc gttcattcag agactgctga tcctcactca tgaagaccct ccagaagaac
     2041 tctgtggctt tcagggagct gagttgctgt cagagaagga tctgaaaaga gtggccaagc
     2101 cagaggagct acagtgggac ttaggaggtc acagggacct ctcccccaac cactgggcag
     2161 agatacatca ggaggtggca aggctgtgca ccttgtgcca aggtgtgctg acctctgttc
     2221 ggcaggccat tgaggagctc gagggagcgg cagaatccaa agaagaggag tcggtgggaa
     2281 tgcctgagcc cctgcaaaag gtgctggcag atcctcggct gacggcgcta cagaggaacg
     2341 gaggagccat cctgatgcgc ctgcgctcca cgcatagcag caagctagag ggcccaggcc
     2401 cagctgtgct ataccaggaa gtagatgagg ccattcacca gctcgtgcgt ctgtccaacc
     2461 tacgggtgca gcagcaggaa caacgccaac gcctacgcca agtccaggag gtgctgcagt
     2521 ggctgtctgg cccaggggaa gagcagctgg ccagcttcac catacctggg aactccctgt
     2581 cagtcttaca agagacagaa cttcgattcc gagcgtttag cactgaggtg caggagcgcc
     2641 tagtccaagc ccgggaagca ttggctctgg aggaagacat cacgtcccag aaagttctag
     2701 atatctttga acaacggctg gagcaggtgg agagtggcct ccatcgggcc ctgaggctac
     2761 agcgtttctt ccagcaggca cacgaatggg tagatgaagg ctgtgctcgg ctggcaggag
     2821 ctgggcctgg ccgtgaagct gtactggcag ccctagccct gcgaagggcc ccagagccca
     2881 gtgcaggcac cttccaagag atgcgagccc tggccctaga cttgggtagc cccgcagccc
     2941 ttcgagagtg gggccgatgt cgggcacgct gccaagagct ggaaaggagg attcagcagc
     3001 agctgggaga ggaagccagt cctagaagcc accgacgacg tcgggcagac agtgccagca
     3061 gcgcaggggc ccagcacgga gcccatagcc cttcgcccag cctcagttcc ctcctgcttc
     3121 ccagcagccc tgggccacgg gcagccccat cacattgctc tctgacccca tgtggagagg
     3181 actatgagga agaaggcctt gagttagctc cagaagcaga tggaagaccc ccaagggctg
     3241 tgctgatccg aggactggag gtcaccagta ctgaagtggt agataggaca tgttcacccc
     3301 gcgaacacgt gctattgggc cgggctggag ggccagatgg accctgggga ataggtaccc
     3361 ctcgaatgga acggaaacga agcatcagtg cccagcagcg tctagtgtct gaactgattg
     3421 actgtgaaca ggaatatata accaccctga atgagccagt gccaccgcct gggcctgagc
     3481 taactcctgg gcttcgctgc acctgggctg cagccctgag tgtccgagag aggcttcgca
     3541 gcttccacgg gacccacttt ctacaagagc ttcagggctg caccgcccac cctctgcgca
     3601 ttggggcctg cttcctccgc catggggacc agttcaacct ctatgcacag ttcgtgaagc
     3661 acaggcataa actggagagt ggtctgactg cgctcacccc ctcggtcaag ggttctatgg
     3721 agggcagccc ttgcttgccc cgggccctgc agcagcctct ggaacagcta gctcggtacg
     3781 cacagctcct ggaggagctc ctgagggaag ctgggcctga gctaagctcc gaacgccagg
     3841 ccctcagggc tgctgtacag ctgctccagg aacaagaggc ccgaggcaga gatctgctcg
     3901 ctgtggaagc tgtgcgaggc tgtgagatag atctgagaga acagggacag ctcctgcatc
     3961 gggacccttt cactgtcatc tgtggccgga aaaagtgcct acgccatgtc tttctcttcg
     4021 aggacctgct cttattcagc aagtcgaagg gttctgaagg aggatccgag acctttgttt
     4081 acaagcaggc tttcaagacc gctgacatgg ggctgacaga aaacatcggg gacagcggac
     4141 tctgtttcga actgtggttt cggcgacggc gtgcacgaga agcatacact ttgcaggcca
     4201 cttcgccaga gactaaactc aagtggacaa gttctattgc ccagcttctg tggagacagg
     4261 cagcccacaa caaggagctc cgagtgcagc agatggtttc catgggcatt gggaataaac
     4321 ctttcctgga cattaaagcc cttggggaac ggacactgag tgccctgctc actggaagag
     4381 ccgcccgaac ccgggcctcc gtagccgtgt catcctttga gcatgctggc ccgtcccttc
     4441 ccggcctctc accgggagcc tgctccctgc ctgcccgcgt cgaggaggag gcctgggatc
     4501 tggacgtcaa gcagatttcc ctggcctcag aaacacttga ctcttctgga gatgtgtccc
     4561 caggaccaag aaacagtccc agcctgcagt cccccaaccc tgggagcagt actcctgctc
     4621 tgagcagtgg cgggatctta gggctatcca ggcagagtca ttcccgagcc ctgagtgacc
     4681 ccaccacgcc tctgtgaact aggaaccaga gtgaccctgt ttgcttgcct ttatgcactg
     4741 gggacaggga aatgtccctc ttgctatgca actgcacacc cctgggacac tgctctgatg
     4801 acaacccact attcttccca gaagactcat ctcggccagg ctgaatggaa ttccattctg
     4861 gggtatcacg ggaaatgaag tgttctaagc cactgaagga gatggggtgg gcattgcaga
     4921 ctttatatgt aattactgtt attatactat ttacattaaa tgtatttact ctcactttga
     4981 ctcccaggag ccagcgcagg cctctggatt aaggtgtttg aactgacttc agtacttctc
     5041 tataaccact aagtaggatt cagaagataa aaccaaggcc agaaagtagc tgtccctccc
     5101 cttgctggcc caacactgac agtctgtgag tgtgggagaa tgcctccccc tcacaggctc
     5161 taggaagctc aacgaactct gaagttcctc ctccattttg cacccactcc ttgaggctga
     5221 gacggtcaga tgggcccagc acagtgcagt agttatctag tgatgtccgc aggccgcagt
     5281 gcaagagaac ccaaggctat ttattaccaa tgctaattct tggggccaca tccagggtca
     5341 ctgaatccga agtctgggcg gaaagcaaag ctttgcatct gtatcaaact cattgcccag
     5401 gaacagtgaa acacaggcag acacgcagac acgcagggcc ttgtgcctca agacacctgt
     5461 ttattgggga catgactctt caacaggggt gacaggaatc gtaccaaaaa tagcaacgtc
     5521 tacagggccc ctgacagggc tagaagggta cagtgccccc cacccccacc ccttatacaa
     5581 aaataaactc tcatgcctat ggaccagcag aaactggcag agtggctcct taacagcagc
     5641 acatcctcta ccagccctag gaccccgttc tttgaccctc acctctgcca cgtctaaggc
     5701 actgtgactc ctctgggctg ggtgggtatt gcttgcccac tctccttcac ccactgccca
     5761 ctttacctct tggtccacct tgggctggga tacgggtccc acactgctcc ctgctggctg
     5821 ctctacccaa ctacctctag cactccccgc tcccgcgggg taagcttact acactaatca
     5881 ctcctaagag ggctccctac cgttcttgac ccccaagacc tgcctctccg gatctagaca
     5941 gccctgggct gccctcctct tctagtggag gactgggagg ggtctcccct gacggtgccc
     6001 ggacataggg tggagatgtg tcagcacggg gctgccggcg gccccgtgca cgacggctgt
     6061 ggtgtacttg cagatgcaag gccatgagct caggagctcc agtggcaaag gggcagaa
//
