LOCUS       NM_001106676            1651 bp    mRNA    linear   ROD 26-FEB-2024
DEFINITION  Rattus norvegicus Rho guanine nucleotide exchange factor 39
            (Arhgef39), mRNA.
ACCESSION   NM_001106676 XM_001063105 XM_233381
VERSION     NM_001106676.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1651)
  AUTHORS   Wang H, Li Y, Wang Y, Han ZG and Cai B.
  TITLE     C9orf100, a new member of the Dbl-family guanine nucleotide
            exchange factors, promotes cell proliferation and migration in
            hepatocellular carcinoma
  JOURNAL   Mol Med Rep 5 (5), 1169-1174 (2012)
   PUBMED   22327280
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BC158673.1.
            
            On Oct 5, 2010 this sequence version replaced NM_001106676.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC158673.1, SRR8487230.157830.1
                                           [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMD00132261,
                                           SAMD00132262 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1651              BC158673.1         1-1651
FEATURES             Location/Qualifiers
     source          1..1651
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="5"
                     /map="5q22"
     gene            1..1651
                     /gene="Arhgef39"
                     /gene_synonym="RGD1310376"
                     /note="Rho guanine nucleotide exchange factor 39"
                     /db_xref="GeneID:298404"
                     /db_xref="RGD:1310376"
     exon            1..155
                     /gene="Arhgef39"
                     /gene_synonym="RGD1310376"
                     /inference="alignment:Splign:2.1.0"
     CDS             18..1052
                     /gene="Arhgef39"
                     /gene_synonym="RGD1310376"
                     /note="vav-like protein C9orf100 homolog; Rho guanine
                     nucleotide exchange factor (GEF) 39"
                     /codon_start=1
                     /product="rho guanine nucleotide exchange factor 39"
                     /protein_id="NP_001100146.2"
                     /db_xref="GeneID:298404"
                     /db_xref="RGD:1310376"
                     /translation="MESLGSSECCPVRQQRARWERKRVCTARELLETERRYQEQLGLV
                     ATYFLGILKAKGTLRPPERQTLFGTWELIYAASLELLPYLEEGQWGPGLQGFCPHLEL
                     YTQFAANAERSQTTLQEQLKKNKRFRRFVRLQEGRPEFRGLQLQDLLPLPLQRLQQYE
                     NLVVALAENTVPNSSDYQQLTRAARLVSETAQKVHAIGQNRKNEQHLLRVQALLSGRK
                     AKGLTSGRWFLRQGWLLVVPPTGEPRPRMFFLFSDALLMAKPRPPLHLLKSGTFVCRA
                     LYPMTQCQLSRVFGHSGGPCGGLLSLSFPHEKLLLMSTDQEELSQWYHSLTQAIRSQK
                     NSAHRSVPAT"
     exon            156..250
                     /gene="Arhgef39"
                     /gene_synonym="RGD1310376"
                     /inference="alignment:Splign:2.1.0"
     exon            251..371
                     /gene="Arhgef39"
                     /gene_synonym="RGD1310376"
                     /inference="alignment:Splign:2.1.0"
     exon            372..490
                     /gene="Arhgef39"
                     /gene_synonym="RGD1310376"
                     /inference="alignment:Splign:2.1.0"
     exon            491..561
                     /gene="Arhgef39"
                     /gene_synonym="RGD1310376"
                     /inference="alignment:Splign:2.1.0"
     exon            562..690
                     /gene="Arhgef39"
                     /gene_synonym="RGD1310376"
                     /inference="alignment:Splign:2.1.0"
     exon            691..920
                     /gene="Arhgef39"
                     /gene_synonym="RGD1310376"
                     /inference="alignment:Splign:2.1.0"
     exon            921..1009
                     /gene="Arhgef39"
                     /gene_synonym="RGD1310376"
                     /inference="alignment:Splign:2.1.0"
     exon            1010..1621
                     /gene="Arhgef39"
                     /gene_synonym="RGD1310376"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 aaaatcctgg gtcaagcatg gagagtctcg gttcctccga gtgctgcccg gtgcgacagc
       61 agcgtgctcg ttgggaacgg aaacgtgtct gcacagctcg ggagctgctg gagaccgagc
      121 ggcgctacca ggaacaactg gggctggtgg ccacgtactt cctggggatc ctgaaagcca
      181 aagggacact acgaccacct gagcgccaga ctctgtttgg gacctgggag ctcatctatg
      241 ccgccagcct agagctgctt ccctacttgg aagaaggaca gtgggggcct gggctacaag
      301 gcttctgccc ccacctagag ctctacaccc aatttgctgc caatgcagag aggtctcaga
      361 ctacccttca ggagcagctg aagaagaata agcggtttcg gaggtttgtg cggcttcagg
      421 aaggtcgccc tgaatttagg ggtcttcagc tccaggacct gctccctctg cctctgcagc
      481 ggctccagca gtatgagaat cttgtggtgg ctttggctga aaacacagtt cccaacagct
      541 ctgactacca acagctcaca cgggctgccc gcctggtaag tgagactgcc cagaaggtcc
      601 acgccatcgg ccagaatcgg aagaatgagc agcatctgct gcgtgttcag gctctactca
      661 gtggacgcaa ggcaaaaggg cttacttcag gacgctggtt cctacgacag ggttggcttt
      721 tagtagtgcc tcccaccggg gagcctcggc cccggatgtt cttccttttc tctgatgcgc
      781 tcctcatggc caagccccgg cccccactgc acctgctgaa gagtggcacc tttgtctgca
      841 gagccctgta ccctatgacc cagtgccagc ttagcagggt ctttggccat tcgggaggac
      901 cttgtggtgg tttgctcagt ctgtcctttc cccacgagaa gctattgctt atgtctactg
      961 accaggagga gctgtcacaa tggtaccaca gtctgactca ggctattcga agccagaaga
     1021 actcagccca cagaagtgtc cctgcaacat gaccttgtca cctacaaatg tgctgggcca
     1081 cattcacagc tatcctgggg tacacgtggc agctgggcat gcctacgaag aatcttacca
     1141 attccagaac tcgggatcct cagggctagg gcagagccaa gaacaaacgg gaatgcactt
     1201 caattgagcc tcagttgaac aagccccttt aatgccatgc cactgggggt ggggtggggc
     1261 ggggctgtaa agctcctgtg gtctgtggcc agctgttatc acatttgcgg ctttgtaaag
     1321 gaggccattt tgttgttgcc tatggtttgt tttatttttg agaaaggatc ttactatgtg
     1381 acccaggctg acagtgaact tgaatgcctc ctgcctcagc ctctcaggtg ttgggtgtat
     1441 aggtgtgtgc tgccgtacct ggctactgta catagttttg tttttcttga gacaaagttt
     1501 catgtagccc agggtggcct taaactccag atcctcttga actacctcct atgatgtaaa
     1561 agttctataa tttatttcct cactggattt taataaagtg ctgctgtttt gtttttgcaa
     1621 aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa a
//
