LOCUS       XM_017591350            6921 bp    mRNA    linear   ROD 11-JUN-2023
DEFINITION  PREDICTED: Rattus norvegicus Rho guanine nucleotide exchange factor
            38 (Arhgef38), mRNA.
ACCESSION   XM_017591350
VERSION     XM_017591350.2
DBLINK      BioProject: PRJNA677964
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_051337.1) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            [WARNING] On Feb 1, 2024 this sequence was replaced by
            NM_001427634.1.
            
            On Jan 21, 2021 this sequence version replaced XM_017591350.1.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_015227675.2-RS_2023_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.1
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/06/2023
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6921
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN/NHsdMcwi"
                     /db_xref="taxon:10116"
                     /chromosome="2"
                     /sex="male"
                     /tissue_type="kidney"
                     /geo_loc_name="USA: Wisconsin, Milwaukee, Medical College
                     of Wisconsin"
                     /collection_date="2019-03-08"
                     /collected_by="Rebecca Schilling"
     gene            1..6921
                     /gene="Arhgef38"
                     /note="Rho guanine nucleotide exchange factor 38; Derived
                     by automated computational analysis using gene prediction
                     method: Gnomon. Supporting evidence includes similarity
                     to: 5 ESTs, 2 Proteins, and 99% coverage of the annotated
                     genomic feature by RNAseq alignments, including 12 samples
                     with support for all annotated introns"
                     /db_xref="GeneID:295449"
                     /db_xref="RGD:1311728"
     CDS             1..2313
                     /gene="Arhgef38"
                     /codon_start=1
                     /product="rho guanine nucleotide exchange factor 38"
                     /protein_id="XP_017446839.2"
                     /db_xref="GeneID:295449"
                     /db_xref="RGD:1311728"
                     /translation="MEPREAAGKETMGSKRKNLTFLRSRLYMLERRKTDTVVDSSVSG
                     DHSGSLRRSQSDRTEYNQKLQEKMTPQAECSSAETPTPEEEQQVGRMMAKRAKIIREL
                     IQTERDYLTDLELCVREVVQPLRSKQIDRLDVESLFSNIESVHQISAKLLSLLEEATT
                     DVEPAVQVIGEVFLQIKGPLEDVYKIYCYHHDEAHSVLESYEKEEDLKQHLSHCIQSL
                     KTIYMQEGKPNLLDMGSLMIKPIQRVMKYPLLLCELRNSTPPSHPDYRALEEAFAAVK
                     DINVNINELKRRKDLVLKYKKNEEEESLKDKLSRLNIHSISKKSKRVTNHLKILTRGD
                     SQVKDNTFNREEKLFRSLEKTVRLCVKNISSCLQHIEEAVPFTLHSVAALCEISYKDG
                     EKNCMEPQSQASNPCHDFAARSQRLILSPLSTLLSLFPGPQKLIQKRYDKLLDCNSSL
                     PRSATTESDLAKREYEALNAQLVEELQAFNQAARKILLNCLLSFVTLLRDLMLVALQA
                     YSTVKTVPLPVLGISEIQNQVLEEVHSLNFVKDNSATFIERKLSFEKKKPTQVLPEVP
                     HQTDVHRSKLLSTYGAEELYRAKRKCNATQEHDVSLLEGELVAVLEQKDPLGSTSRWF
                     VDTGFVKGYVYSSFLRPYNPGKEQKVDAENRFCDDDFENISLFVSCRPAGDSVSISDS
                     SSSLSGSCGKFETNGADADNFQEVDEQVFYAVHAFQARSDHELSLQEYQRVHILRFCD
                     LSGNKEWWLAETQGQKGYVPANYLGRMTYA"
ORIGIN      
        1 atggagccca gagaagccgc tgggaaggaa accatgggaa gcaagaggaa gaacttgacc
       61 ttcttgagat ccaggctgta tatgctggag aggaggaaga cggatactgt ggtggacagc
      121 agtgtttctg gggaccactc tggctccttg aggaggagtc agtctgacag gacagaatac
      181 aaccagaagc tacaagaaaa aatgacacct caggctgagt gctcctcggc agaaacccca
      241 acccctgagg aagagcagca agtgggacgg atgatggcga aacgggcgaa gatcatcagg
      301 gagctcatac agacggagag ggattacctc acggatctgg agctgtgcgt tagagaagtg
      361 gtccagccac tgagaagcaa acagattgac aggctggacg tggagagctt gttcagcaac
      421 attgaatccg tgcatcagat ttcagccaag ctactgtcct tgctggaaga ggccacgaca
      481 gacgtggaac cggctgtgca agtcatcgga gaggtattct tgcagattaa aggaccgctg
      541 gaggatgttt ataagatcta ctgctatcac catgacgaag cgcacagtgt tctagagtcc
      601 tacgaaaagg aagaggatct gaagcaacat ttgagccact gtatccagtc cttaaaaact
      661 atatatatgc aagagggcaa gccgaacctg ctggacatgg gttctttgat gatcaaaccc
      721 attcagcgag tgatgaaata tcccctgctg ttgtgcgaac tccggaactc gaccccgccc
      781 tcccacccag actacagagc cctggaggaa gccttcgctg ctgtgaagga cattaatgtc
      841 aacatcaatg agctgaaaag aaggaaggac ctagttctaa aatataagaa gaacgaggag
      901 gaggagtccc tcaaagacaa actgtctaga ctaaatattc attcaattag caagaagtcc
      961 aaaagagtca caaatcatct gaagatcctg accagaggag actctcaggt gaaagacaat
     1021 acctttaaca gagaagaaaa gcttttcaga tcgctcgaaa agactgtgag actttgcgtg
     1081 aagaacattt catcctgcct tcagcacata gaggaagccg tgcccttcac tctgcatagt
     1141 gtggcagcgc tctgtgagat ttcatacaag gatggagaga aaaactgcat ggaaccccag
     1201 agtcaagctt caaacccctg tcacgacttt gcagctcgct ctcagagact catcctgagc
     1261 cccctgtcca ccttgctatc cttattccca gggccccaga agctcatcca gaaacgctac
     1321 gacaaactcc tggactgtaa tagctccctg cctcggtcag caaccactga atcagactta
     1381 gccaagagag agtatgaggc cctcaacgcc caactcgtgg aagagttgca ggcattcaac
     1441 caggcggcca ggaagatcct gctgaactgc ttgcttagtt tcgtcaccct cctccgggac
     1501 ttgatgctgg tggctctgca ggcttattcc acagtcaaga cggtgccact gccagtcttg
     1561 ggcatctcag agattcagaa tcaagtgctg gaagaggttc acagcttgaa ttttgtaaag
     1621 gacaacagtg ccacctttat tgagaggaaa cttagctttg aaaagaagaa gcccacacag
     1681 gttctgccag aagtgccaca tcaaactgat gttcaccgct ccaaacttct gtccacatat
     1741 ggagcagagg aactctaccg agctaagcgc aagtgtaatg ccacacaaga acatgacgtc
     1801 agtcttctag aaggggagct ggtagctgtt ctggagcaga aggatcccct ggggagtaca
     1861 agcaggtggt ttgttgacac cggatttgta aaaggctacg tgtactcttc cttcctgagg
     1921 ccctacaatc cagggaaaga gcagaaggtg gatgcagaga acagattctg tgacgacgat
     1981 ttcgagaaca tcagtctctt tgtgtcttgc cggccggccg gtgacagtgt cagcataagc
     2041 gacagcagct catctcttag tggctcttgc gggaagtttg aaacaaatgg tgctgatgcg
     2101 gataattttc aagaggtaga cgaacaggtc ttctatgcag tccatgcctt tcaagcacgg
     2161 agcgaccatg aactcagcct tcaggagtac cagagagtcc atatacttag gttctgcgat
     2221 ctaagtggga ataaagagtg gtggttagct gagactcaag gtcagaaagg gtatgtgccc
     2281 gctaactacc ttgggaggat gacgtatgcc taaggaaatg agcgacattt ccccggcaag
     2341 ctgcttattg actacctcat gaagccgacg acgaaacttc aaacccgaaa gcaagagacc
     2401 tcggaactgc atgaacagcg taccacgttt tgaggacaat cttgcttcct aataggacac
     2461 cttcaccgat gtataaagaa taatggttga cagaaatact accaacaaaa acagcaggta
     2521 aaacagccta ggctctgact atatttataa aggcagagat cttttgagaa gacatatttt
     2581 cactgatcat caccgaagag tggatctaag aggaaggttt ttccacttta tcgtaatttt
     2641 tttcctgtac tttgcctcag acatattgtt tttcacattt cttatttgta catgtacctg
     2701 tttacatgca cacataatat acttggcagt ttatacagca tgagcacaat acagattatg
     2761 cacgcatgta taagtcacag agtaaactaa ttacgcagaa aaacgacagg caattagaag
     2821 tctttaatat agggctccat tttaaatgca tctttaatga aagggagacg ataaggtatt
     2881 agtaatatta aaaacttact caatgtgtac tccatgatgc cccttgcttt caatgatttc
     2941 taggtcatga tttaatgcag tgtaaagagt aaacactgct agcaaaggta gagggggtcg
     3001 agcacaggca gcatggttcc gacgtctgtt cctactgagt acaccggaca cgccttgagt
     3061 gcaaaagaga gatgtgaaca atgggcctgg aggaaatcag atccacattt caatctttaa
     3121 cagcttttca aaattaaggg cttccacgag agccggggag agaagaatga agtgtcaaag
     3181 tttattcttt gtaattctta tctttgtgat gaagcactat ggaagtgtaa tggttttaaa
     3241 gctgtcacaa acgactactg acgaggcttt aatgaagaaa cagttcggca tcactctgat
     3301 ttagaggtac atgagcagtg cacgtcctac ttcagagcca gggtgcaaat acattgagca
     3361 gccagtttgt acttagacga ggtgtggagg actgcattag caccatggta gggcattgtg
     3421 ctttaaattt ggcgactccc ctgagaactg tcctccaaaa tttcaggcat attcagtcaa
     3481 gacattaatg gattcaaaaa gagaaagcag gacagacgca gggatgaaat gaaccagaga
     3541 acacgctcag gaggagggaa ggagaactaa agtagttgga ggcaacaact ccatagagaa
     3601 tattttatga agaccgaaat gcctggcatg tgtgtccttg gtcagcattc tcaaatagct
     3661 gctgtacatc aggaactctg ataacattga ggggtttagc acagtgcaaa tcaatgcagt
     3721 acccggccat gcaaagttta gagtctaaag aggacagcag tgggattata gaagaaaacc
     3781 cacggtgatg cctactgaga aacagtgtgt ttaggatcat ggaacaggga ggcttctaat
     3841 tttgtttaat ttccagtggt tactctttta taattacagt agattttaat tgcctataaa
     3901 attcctaatg acatgtttta agatttgtta ctttgaaaga tttgatccat tcaatatata
     3961 caatatatca tatatatgat aaccatatat atacatatat atatatggtt acatttatta
     4021 ctgagcaata tccataacaa aataaagagt tctatttctc ccagggtagc tgactgaata
     4081 ccataccttc tccccaaagc agaagtagga tttttacatg aaagaaacaa tttatactac
     4141 tactaagaac attaaagttg ttttataaca ttctcatgac attggttttg ttgtagggca
     4201 acaaaagact ttctaaaaga tattagagac tttaaaaaag ttaatttccc tttgaattca
     4261 gttttaacac atgactttgt ttgcctaagt ttaagcaaaa agaaatatga agttgctact
     4321 taagaacact atgaaaacgg ttcaaagagg cataattggt acatggcggt gtgcacgtgc
     4381 acacctgcac accacaccaa gcttcaaggt tttacacaac agtgaaggat tataccaata
     4441 gcacagttgt gcttttctgg ctgaaatcag tgattagatg caggagtttt gtctactgat
     4501 gtgacactag gagtgatgct tcctgtttga cctttgaaaa acctgtgcct ggaaaatcaa
     4561 tccttcactc agctcctgag agagaactgt tatgaagcca gtaactgcag ctttcctaac
     4621 atgatgtgcc cattactaga aatgagctct gaaaaattat ataatacctt cattttctac
     4681 tttttttaaa aactttttta cttaaaatca agtaactcgt aattttgcaa ttagacattg
     4741 ttttaataga ccccagagaa ataaatttcc aagaaagttt atagtttata ggagatatat
     4801 atatatacat atatatatgt acatatatat atgtatatat atgcaggcta gtgtgttttt
     4861 ttattccttt taaaattaaa attgtacaga atagtatcct ctgacgtggg tgatattttt
     4921 tgccaagatg aagaggaagc ttctgtagtt atttttctaa ataaataaaa atatatgcat
     4981 tttatttaca ttttattttg aaatgcacac gttaaaactt ctagtataca taatatacag
     5041 tgtgaaatat tcatctagta acataaaatt atcattggtg cacaatcatg aaaaagtccc
     5101 aaagcctgtt tctgaactta ccttatactt aagagaaaga cattgacttt gaaggatagg
     5161 cagagaaaag ataaaaatgc acgtttagtc acagcaatga agcaatgggt aacagatgcc
     5221 gaatgctgga gcattctaaa tcgttccaaa atacaattca gatttttgag aaaccacttt
     5281 taaaatgcct gatgctactt gagatgaaca tagtctgggt ggttttcaaa aacggttgtt
     5341 tcaactactg agacatggaa ttgtcacttc ttggatcttt atcctccccc attgacttta
     5401 caaagctgta tgaataacag gagtaaatta taaaacataa aaacccttta agttgtttgt
     5461 agtaactata gcttcctaat atatgcactg cattgctaac tagtgaaaat cctagacctt
     5521 tcaaaactca gaccaaatga tcctatacag tatatcatgg ccaataaggt tgtgatttca
     5581 gtcactgact agacagacac tggacttgga gttctgtagg aatagatcct gtgtaaagaa
     5641 tgcaaatctt acaagtctaa ttctgtagtt gcttcctcct ctatatacac acagatataa
     5701 aattatatat aatgtccaaa ctacagctct tcaggtctac tggatctcaa gttgaggtct
     5761 tattgtagct actgttttca cagttgtata ctctagttag atgcaggtaa aatttgcata
     5821 ttttgaaaga actcaacact ttagaaaaca ctctagaatc aagatgtccg tgtttggaaa
     5881 tccccgagaa gatactttta ctaaattagt tttgttttgc ttaaaattcc accgaggcat
     5941 ctgagcgtat ccatcgcatt tctgatttct tgtgatttta aaatttcatt ttgttaaaat
     6001 ggatgtattt tctgtgaaac ctgtaggtct taagaattta taattgtaac taataaaagc
     6061 actaccatgc ccttgtgaag acctggagta atctaatttt ttaaatacag atgtgcttta
     6121 tactggagtc acattctggt acactcacca tgggtctaaa gcaccctgct ctatcatagt
     6181 tcagcgagtc agtactacat gtagagtagc agttgcttgg tgtcacgatt acgtgaatta
     6241 ctgggagctg caatctgttg cccctacctg gaaatgatct gaaatagtct tacagagtgt
     6301 gtgagtgctt caggaggatg acttgaagtg cagatgctac taaatggata tgacttgcac
     6361 actactggaa aaaaaaccaa caaaagcact gtaaaccagg ggtcatttgt attctttcat
     6421 tttatcttga ctgaattgtg ttttacaaag tgggaaacta acacaaaagg gttgaaagac
     6481 cagcattctt tcagtgtcat tttgtctcat tttttcaagt cactaaactc tgtggttaat
     6541 ctcataaatt acaatatgaa aaacaggaaa aggatactga ccaaaatagt ttgaatcgtc
     6601 aatcctaaat ctttatacaa gaacacttgc tgttgtggtt gttactgcgc tgtttcccct
     6661 tggctcctgt gtttcatcat tttgttgcca tctggtggtg ctttttggaa agttatggga
     6721 cctagaggcg gtaaagactt actggaagaa gccttcactg ggagctagat tgaggtttta
     6781 tagcctggct ctatgtcctg tttcctatca gctgagacaa gctgatcaac tggcctcatg
     6841 gtcctgccgc catgctttca ccatcatgat ggatggtatc ccttgagagc tgtacgccaa
     6901 aataaatcct ttctccctaa a
//
