LOCUS       NM_001100974            4955 bp    mRNA    linear   ROD 31-MAR-2024
DEFINITION  Rattus norvegicus Rho guanine nucleotide exchange factor 37
            (Arhgef37), mRNA.
ACCESSION   NM_001100974 XM_001058158 XM_225892
VERSION     NM_001100974.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 4955)
  AUTHORS   Gaudet,P., Livstone,M.S., Lewis,S.E. and Thomas,P.D.
  TITLE     Phylogenetic-based propagation of functional annotations within the
            Gene Ontology consortium
  JOURNAL   Brief Bioinform 12 (5), 449-462 (2011)
   PUBMED   21873635
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000018.1.
            
            On Apr 13, 2021 this sequence version replaced NM_001100974.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643297.50327.1,
                                           SRR26643299.62951.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA5760383,
                                           SAMEA5760386 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-116               JAXUCZ010000018.1  57270916-57271031   c
            117-313             JAXUCZ010000018.1  57255075-57255271   c
            314-437             JAXUCZ010000018.1  57253723-57253846   c
            438-585             JAXUCZ010000018.1  57249499-57249646   c
            586-785             JAXUCZ010000018.1  57243150-57243349   c
            786-916             JAXUCZ010000018.1  57241575-57241705   c
            917-1021            JAXUCZ010000018.1  57240783-57240887   c
            1022-1132           JAXUCZ010000018.1  57240028-57240138   c
            1133-1462           JAXUCZ010000018.1  57238518-57238847   c
            1463-1591           JAXUCZ010000018.1  57235771-57235899   c
            1592-1787           JAXUCZ010000018.1  57233800-57233995   c
            1788-1948           JAXUCZ010000018.1  57232278-57232438   c
            1949-4955           JAXUCZ010000018.1  57228033-57231039   c
FEATURES             Location/Qualifiers
     source          1..4955
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="18"
                     /map="18q12.1"
     gene            1..4955
                     /gene="Arhgef37"
                     /gene_synonym="RGD1560471"
                     /note="Rho guanine nucleotide exchange factor 37"
                     /db_xref="GeneID:307398"
                     /db_xref="RGD:1560471"
     exon            1..116
                     /gene="Arhgef37"
                     /gene_synonym="RGD1560471"
                     /inference="alignment:Splign:2.1.0"
     exon            117..313
                     /gene="Arhgef37"
                     /gene_synonym="RGD1560471"
                     /inference="alignment:Splign:2.1.0"
     CDS             128..2158
                     /gene="Arhgef37"
                     /gene_synonym="RGD1560471"
                     /note="probable guanine nucleotide exchange factor
                     FLJ41603 homolog; protein 2-88; scaffold protein tuba 3;
                     Rho guanine nucleotide exchange factor (GEF) 37"
                     /codon_start=1
                     /product="rho guanine nucleotide exchange factor 37"
                     /protein_id="NP_001094444.2"
                     /db_xref="GeneID:307398"
                     /db_xref="RGD:1560471"
                     /translation="MADFETDEASSKSESPEQEGQGSEDKSLLHQRLAIRELIDTEVS
                     YLHTLRLCTSDIRGHLQQLPPGDLDILFSNIDDIIQVSSRFLHGLQETACKEEKQAHL
                     IGNLFLEFQEELEQVYKVYCANYDQALLLVKAYQKEPELQKEIQGIIEAAVPQAGPSG
                     LSFLLVIPLQRITKYPLLLQKILENTPADASAHPVLQRATSALQDVNSNINEYKMRKE
                     VALKYTKVEQLSLRERLARINTHTLSKKTTRLSQLLKQEAGLVPRTEDKEFDDLEERF
                     QWVSLCVTELKSNVAAYMDNLEAFLCFRPHERNLDIPGGAAEQYCSLARDLQLQAFLQ
                     FKQRLTGLVWQPLCSLARALVGPQNLIKKRLDKLLDFERVEEKLLDVGSVTYEEEAAR
                     HTYQALNSLIVAELPQFNHLVMQWLGQILRTFVVLQRDLADQVLRRAESSMALLPHRH
                     VSEPDFQKLLEDTLGQSSSQLRHFRESFEKVLPPSTSQPLLPGSEHQMQSLLTRYGPG
                     KIYQVTSNINGTGTLDLTLPRGQIVALLQNKDTKGNNSRWLVDTGGHRGYVPAGKLQL
                     YHPINPSEKEPRRQTGMPEDYWLPTPEPTQPSVPTVPTMSQVVAVYPFVARSTHELSL
                     QAGQPVTILEAQDKKGNPEWSLVEANGQRGYVPSNFLARTPSPTPWGWNLPS"
     exon            314..437
                     /gene="Arhgef37"
                     /gene_synonym="RGD1560471"
                     /inference="alignment:Splign:2.1.0"
     exon            438..585
                     /gene="Arhgef37"
                     /gene_synonym="RGD1560471"
                     /inference="alignment:Splign:2.1.0"
     exon            586..785
                     /gene="Arhgef37"
                     /gene_synonym="RGD1560471"
                     /inference="alignment:Splign:2.1.0"
     exon            786..916
                     /gene="Arhgef37"
                     /gene_synonym="RGD1560471"
                     /inference="alignment:Splign:2.1.0"
     exon            917..1021
                     /gene="Arhgef37"
                     /gene_synonym="RGD1560471"
                     /inference="alignment:Splign:2.1.0"
     exon            1022..1132
                     /gene="Arhgef37"
                     /gene_synonym="RGD1560471"
                     /inference="alignment:Splign:2.1.0"
     exon            1133..1462
                     /gene="Arhgef37"
                     /gene_synonym="RGD1560471"
                     /inference="alignment:Splign:2.1.0"
     exon            1463..1591
                     /gene="Arhgef37"
                     /gene_synonym="RGD1560471"
                     /inference="alignment:Splign:2.1.0"
     exon            1592..1787
                     /gene="Arhgef37"
                     /gene_synonym="RGD1560471"
                     /inference="alignment:Splign:2.1.0"
     exon            1788..1948
                     /gene="Arhgef37"
                     /gene_synonym="RGD1560471"
                     /inference="alignment:Splign:2.1.0"
     exon            1949..4955
                     /gene="Arhgef37"
                     /gene_synonym="RGD1560471"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ggcaactgac aaaggcgggg gcgcgctctg cgcgtgcaca gcagacagag gagctgcact
       61 cgcagccgga gcccagcggg tgcgagtgac accggagggc atccggcgcg tgcgcgaacc
      121 tgtggacatg gctgactttg aaacagatga ggcctcttcc aagtcagaga gccctgagca
      181 ggaaggccag ggttctgagg acaaatctct gctccatcag aggctggcca tcagagagct
      241 catcgacaca gaagtctcct acttgcacac actccgactc tgtacctctg acatcagagg
      301 ccacctacag cagctgccgc caggagatct ggacatactg ttctcaaaca tcgatgacat
      361 catccaagtg agcagcagat tccttcacgg gctgcaggag acagcctgca aggaagagaa
      421 acaagcacac ttgattggta acttattcct ggaattccaa gaggagcttg aacaagtcta
      481 taaagtctac tgtgccaact atgaccaggc cctgctgctg gtcaaggcat accagaagga
      541 gccggaactc cagaaggaga tccagggcat catcgaagct gcagtgccac aagctggacc
      601 ttcgggtctc agtttcttac ttgtaatccc tctgcagagg attaccaagt accccctcct
      661 gctgcagaaa atcctggaga acacacccgc ggatgccagt gcccaccctg tccttcagag
      721 agccacctct gccctccagg atgtgaacag caatatcaac gagtacaaga tgcgcaagga
      781 agtggcctta aagtatacca aagtggagca gctgagcctt cgggagcggc tggcccgcat
      841 caacacccat actctttcca agaagaccac caggctgagc cagctgctga agcaggaggc
      901 ggggctcgta cccaggacag aagacaagga atttgatgac ttggaggaga gattccagtg
      961 ggtgtctctg tgcgtgacag agctgaagag caatgtggca gcttacatgg ataatctgga
     1021 ggctttcctc tgcttccggc cacacgagcg gaacctggat atccctgggg gagctgcgga
     1081 acagtactgc agcctagcga gggaccttca gctccaggcc ttcctgcagt ttaagcagcg
     1141 gttaacaggc ctggtgtggc aaccattgtg cagtctggcc agagccctgg ttggccctca
     1201 gaacttgatc aagaaacgtc tggacaaact cctggacttc gagagagtag aagaaaaact
     1261 gttggatgtg ggcagtgtga cctatgagga agaggcggcc cggcacacgt accaggcact
     1321 caactccttg atagtggctg agctcccaca gtttaaccac ctcgtcatgc agtggctggg
     1381 ccagattctg cgcacatttg tggtcctcca gagagacctt gcagaccaag tgctgcgaag
     1441 ggcagagagc agcatggccc tgctgcctca tcgccacgtc tccgagccgg acttccagaa
     1501 gctgctggag gacacgctag gccagagcag tagccagctc cgccactttc gggagagctt
     1561 tgagaaagtg cttccaccct ccacctcgca gccactcctt ccagggtctg aacaccagat
     1621 gcaatctctc ctcaccagat atggccctgg gaagatatac caggtgacaa gcaacatcaa
     1681 tggcactggg accctggacc tgacactacc tcggggccaa atcgtggccc ttctacaaaa
     1741 caaggacacc aaaggcaaca acagtcgctg gctggtagac acagggggac accggggata
     1801 cgtgccagct ggaaaacttc agctatatca ccctatcaat cccagtgaga aggagcccag
     1861 acgccagaca gggatgcctg aagactactg gcttccaacc ccagagccca cccaaccctc
     1921 tgtccccact gtcccgacca tgagccaggt ggtggccgtg tacccttttg tggccaggag
     1981 cacccacgag ttgagtctac aggcaggcca gcctgtgacc atcctggaag cccaagacaa
     2041 gaaggggaac ccagaatgga gcctggtgga agcaaacgga cagaggggat atgtaccttc
     2101 caactttctg gccaggactc cgagtccaac tccctggggc tggaatcttc cctcttagca
     2161 tgacctcttg ggaaccccat tcctaaggaa aggcggaggc ttaaaagctg tgtgacctag
     2221 gggggatggc gcaaagcaca gtgggaatgg gagaggcgtg aagggcaccc agaaggcagc
     2281 aggaagtgat tactaggcct tacagaatgc ctggtgtggg aggccacagt gggtggttcg
     2341 gcagtgccac tgtgatctgc ataaagaagc catctctagg ccacagctga ttagctaagg
     2401 cttgccacag ctcgaagctc accctacctc ttcttacctc tttcatgtct aggatgaatg
     2461 tggcctgtgt tagttgcagg tggggcctct ctgaagacga ccaggcctgc ttggctctgt
     2521 agtacacttc ccacagtgtt gccaggaaac accgtggctc gtcagtcatc ttttctttct
     2581 tactgccttg cactgagtta ttgtgaacag tgaactgtgg agagtcctgc tcaaggggaa
     2641 gccatgggcc taggttctga ggagattgtc tactgtgtct gggaatgggt gtggtctctg
     2701 cataggtctg gaacgtgtgt acaaacttgt aggtggttcc agggaagagg ggaatttgag
     2761 ggtgaattag tgggtgtgag aggctgattg caatggtaac tactggtgtt ttcttcagag
     2821 taggaaacaa aggaacttgt gacataggtg actactggcc tggcaagtcg ggtaagtgag
     2881 ggatagcgtg gtttcctggc tctgggtaga agaaccacga gaacacaggg ggcctagctt
     2941 tgcctctgag gacctggagg cagtaaggag ctgaggttgg gtagatgtga ggcctaagac
     3001 ataggaccca attgcagttt tccacgtagg gaaaaaaaca aaacaaaact aagtcatggg
     3061 aagcagtagg gatggcatga ggctggaggt gcaagggtcc cttgtcaacc aggatgtgcg
     3121 acaccaacac aaagactgtt agtggtgtca ggatggccca gccattgcct ggcgtgggtt
     3181 agcagagtaa agcagtcctg ttgctacctg tcacgtccca tgttcaggcc aatggtgtcc
     3241 ttttccttaa acccaggctc tgattccagg cccagtcagc atggattaac aatagacaat
     3301 tgttaggggg ttctgttctg tgtgagcatc atggagtgtg caaactaaca aggttatgac
     3361 atcactaggc aatataatct catgggactt tgacatacac aaagccattg cctatagctg
     3421 gctgttgcat ggcgcatgac atatgggtac aatctaggta gccaaagtcc cagtgcctgg
     3481 tacttgatga gcaggtcatt tctcaaatct ggaaacagaa acccctcaaa gcagaccttg
     3541 tttctggatg acaggcccac aggggcatgc tgggtgtcgt cactactggg caatgtccct
     3601 aggctgttgc tttaggtcaa gagtcatcag aagatcccaa gacagtgaaa agggtgatcc
     3661 actctgacct gtgtacaact gacagatttg gaatcgaccc tcttgagaga cagagagtaa
     3721 aacaggtggc tatttcagtg tttccaagac tacgtctgtt tttacaactc aagcgcctgt
     3781 ttgttaactt tggcttctga agggctcttg agaaaggcag ctcgcctgtg tcagacggtc
     3841 tgtaatgtgc ctcctctggg cttgttgaag caccaatgcc ggatgatgca agagcaaggc
     3901 tacgcagctc ctttcccaac ctcaggttct ctcgaaggac gttctcagct cagtttcctg
     3961 tccgtttcct tctcgggctt ctaatcaaaa caggaagcat agacaaaaca cacgacaaag
     4021 caggctgtac ctgcagcttc cacagctcgt tgtgaagctg agactctagc ttggagttct
     4081 tagcatggct cttcgctgct gcaattacct gggttgccct aaacggcagc aaaccaggag
     4141 cccacccaga gagagctgat gtcattcatc tgggcacgat catggccttg ggcttcagga
     4201 agctacccag gtgaatctca caggtagcca cgttaagaac ctctgcctta gacatgcaga
     4261 ggtaaacagc tagacctggt cagagttggg acagggtaag ttaagtcatg ccccacctga
     4321 gctttgcgct ggctctctaa gcaggaagct ttggaagcag tttggagtag gacagcctgt
     4381 tctgtcaggt cccaaaatat atctttatta agtgccgtta aaggggacct gaatgaaatt
     4441 gaatgttctt gtaggcataa gggagaaaaa aaatgaaata tactttgaac caaggctatc
     4501 tcatgaagga gaaataaaaa tgtgtccagt acatgtgggt tatagcttct cagaccaggg
     4561 ggtgagatta aagtcactgg agagtgagag aaagcatact gagaagatgg agcatggcct
     4621 ggatcttcac ccagggactc tgtgtaatgt gcctttttac cccaatgcct agagccattg
     4681 cactgtgtct tatttatttc actcttgggc tgtcacgtgc acgctcacaa cgagaattgc
     4741 ctaagaatgg aacagaactc ccaggagtcg aagagtggtt catatggtac cccctgatcc
     4801 tcaaagtgaa gtgggaactc tttaaccctt tgagccccaa cgtagtttag gatacaggga
     4861 gacgattgta ttatccaagg gaagacgagg gaattcttga gtcgtgtgat gagcgtgatg
     4921 tgaccactgg caataaagga cttagtatga ctcca
//
