LOCUS       XM_039113069            3872 bp    mRNA    linear   ROD 11-JUN-2023
DEFINITION  PREDICTED: Rattus norvegicus Rho guanine nucleotide exchange factor
            33 (Arhgef33), transcript variant X1, mRNA.
ACCESSION   XM_039113069
VERSION     XM_039113069.1
DBLINK      BioProject: PRJNA677964
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_051341.1) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            [WARNING] On Feb 22, 2024 this sequence was replaced by
            XM_039113069.2.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_015227675.2-RS_2023_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.1
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/06/2023
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3872
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN/NHsdMcwi"
                     /db_xref="taxon:10116"
                     /chromosome="6"
                     /sex="male"
                     /tissue_type="kidney"
                     /geo_loc_name="USA: Wisconsin, Milwaukee, Medical College
                     of Wisconsin"
                     /collection_date="2019-03-08"
                     /collected_by="Rebecca Schilling"
     gene            1..3872
                     /gene="Arhgef33"
                     /note="Rho guanine nucleotide exchange factor 33; Derived
                     by automated computational analysis using gene prediction
                     method: Gnomon. Supporting evidence includes similarity
                     to: 2 ESTs, 1 Protein, and 100% coverage of the annotated
                     genomic feature by RNAseq alignments, including 3 samples
                     with support for all annotated introns"
                     /db_xref="GeneID:500608"
                     /db_xref="RGD:1560224"
     CDS             930..3575
                     /gene="Arhgef33"
                     /codon_start=1
                     /product="rho guanine nucleotide exchange factor 33
                     isoform X1"
                     /protein_id="XP_038968997.1"
                     /db_xref="GeneID:500608"
                     /db_xref="RGD:1560224"
                     /translation="MEKPKTKQGENEHMPVNNPSTQIYQLQALASELKTGFTEAMQEL
                     TRIQHGEYALEEKVKSCRCSMEEKVTEMKNSLNYFKEELSNAMSMIQAITSKQEEMQQ
                     KIEQLQQEKRRESRKVKAKKAQKEEHGAQAGPASAPASAPAQGSPFRSINVPESGLPS
                     EDFTNMLPSQTYEKAQESRSVHVGDGNVKGMMGPGVNPTTPESDENLKPSLSAEIQSK
                     GHHTSGLWRQPKDGKEWGEEYVTKDHPDKLKDSGQGRHSSLENVLCETSLAAKRQTVA
                     LELLESERKYVINISLILKIKATFQGSDGKRNPKERSLFPGSLRYLIQQHLDLLHALQ
                     ERVLKWPRQGVLGDLFLKLTNDENNFLDYYVAYLRDLPECISLVHVVVLKEGDEEIKS
                     DIYTLFFHIVQRIPEYLIHLQNVLKFTEQEHPDYYLLLVCVQRLRVFISHYTLLFQCN
                     EDLLIQKRKKLKKSSMAKLYKGLASQCANAGQDASPTAGQEAVRDSGIHSEEMLQPYP
                     STPSSAPAVTHLMAPAKKGQQQQQQQQSLMESMQPGKPGDWEMEGRKHERPESLLAPA
                     QFCAAEQDVKALAGPLQAIPEMDFEPSPAEPLGNVERSLRGPPELLPDARGFVPAGYE
                     EFEYGGEIFALPAPYDEEPFQAPALFDNCSPASSESSLDICFLRPVSFAMEAERPEHA
                     LQPLPKSATSPASSSGAYKLEAAQAQAHGKAKPLSRSLKEFPRTPPAEGVAPRLYSTR
                     SSSGGRAPLKVERAPASHGPAAAAAASRGAPRTFFPQQRSQSEKQTYLEVRREMHLED
                     ATRFCPKEERESEQTSFSDQNPRQDQKGGFRSSFRKLFKKKSSGSEYREKTNENPSMD
                     PSPTKQDFFRNRLALANDLDQGTAV"
ORIGIN      
        1 ttgttttttt atattttaat tctcaaatta ttaagtgttc cctatatatt tttcagatta
       61 aagttttttt gtcgttcatt ttctcaagat agggtttctc tgtgtagccc ctgctgctct
      121 gtagacttaa aactcacaaa gatccatctg ccttgacctc tagagtgctg ggattaaagg
      181 cctgtgacac cacaggaggc caattatgtg attttagaat atatatgttt aattttgtga
      241 gggggggctg ggaagatatc atggaggcca gaagaagaca ttagattcct ctggagaatg
      301 gagccagagt tacagacagt tgtgagctgc ccagtgtgag tgctaggaac caaaattggg
      361 tcttctgcaa gatcagaaat tattcttgag ggctgagccg tctcttcagc cctgagtatg
      421 tgtttttaag tcctttattc tgttcatatg ttatatatat attttttttt tttttggttc
      481 tttttttcgg agctgaggac cgaacccagg gccttgcgct tcctaggcaa gcagtgtgag
      541 aacagacaag aagcatagac caaactagaa cctctgcatc acagagcaag caacagagtg
      601 ggaaagaaag agaagaaaga agggaagaaa gaagaaaaga aagtcagcca aaaatcctcg
      661 cctggattga ggaggggcgc atgaggctac cccagcttct tcctgtgatc tttaagacac
      721 tccagagtcc agagaagcct cgctctgagg atgagctaac cacagcaggc accatgggac
      781 cctctagagt aatcaggaag aagacttcca aaacctgatg tgatgtctcc tgctggagac
      841 ggggcacgag gtgcagggaa ggggaggtgg cctgatccag gacgaggatg acgcaatgct
      901 gaagctggag gaaagaagca acaggcacca tggaaaaacc caaaactaag caaggagaga
      961 atgaacacat gccggtgaat aacccgtcca ctcagattta ccagctgcag gccctggcct
     1021 cggaactgaa aactggcttc acagaagcaa tgcaggaact gacacggatc caacatggag
     1081 aatatgcttt ggaagagaag gtcaagagct gcagatgttc catggaagag aaagtcaccg
     1141 agatgaagaa ttccttaaac tacttcaagg aagagctgag caatgcgatg tccatgattc
     1201 aggccatcac ttccaaacaa gaggagatgc agcagaaaat cgaacagctt cagcaggaga
     1261 agagaagaga atctcgaaag gttaaagcca agaaagcaca aaaggaagaa catggtgcac
     1321 aggccggacc tgcatctgcg cctgcgtctg cgcctgcgca aggaagcccc ttccgctcca
     1381 tcaatgtccc agagtctggt ctccccagtg aagacttcac caacatgttg ccttctcaga
     1441 cttatgaaaa agcccaagag tcaagatctg ttcatgtagg agatggcaat gtgaagggga
     1501 tgatgggtcc tggagtgaac ccaacaactc cagaatcaga tgaaaacctt aagccttctc
     1561 tctcagctga gatccagtcc aagggccacc acacatctgg cctgtggaga cagcctaagg
     1621 acggcaaaga atggggcgag gaatatgtca caaaagatca cccagataag ctgaaggact
     1681 cgggccaggg tagacacagc tctctggaaa atgttctatg tgaaacctct ttagccgcaa
     1741 aaaggcagac tgtggctctg gagctgctgg aatccgaaag gaaatacgtc atcaacatct
     1801 ctctgatcct gaagataaag gcaacattcc agggctcgga tggaaagagg aaccccaagg
     1861 agagaagcct cttccccggc tccctgcgct accttatcca gcagcacttg gatttgcttc
     1921 acgcgctgca ggagagggtc ctgaaatggc cacgccaagg agtcctcgga gacttattcc
     1981 tgaagttgac aaatgatgag aataatttct tggattacta tgttgcctac ctgagggatt
     2041 tacccgaatg catctcactg gttcacgttg tggtgctgaa ggagggtgat gaagagatta
     2101 agtcggatat ctacacccta tttttccaca tagtacagcg catccctgaa tatctgatac
     2161 acctgcagaa tgttctgaag ttcacggagc aggagcaccc cgactactat ctcctgcttg
     2221 tgtgtgtcca gcgcctccga gtgtttatct ctcactatac cctgctgttt caatgcaatg
     2281 aagatttgct tatccagaag cggaaaaagc tcaaaaagtc atctatggca aagctgtaca
     2341 aagggctggc ttcccagtgt gccaatgctg gccaagatgc ttcccccact gcagggcagg
     2401 aggctgtccg agacagtggg atccactcag aagaaatgct ccaaccctac ccttccactc
     2461 ccagttctgc ccctgctgtc acacatctga tggccccagc gaagaaaggc cagcagcagc
     2521 agcagcagca gcagagcctc atggagagca tgcagcccgg gaagccagga gactgggaga
     2581 tggagggcag aaagcacgag cggcccgaga gcctgctggc gccagcgcag ttctgtgcgg
     2641 ccgagcagga cgtgaaggcg ctcgccgggc cgctgcaggc catcccagag atggacttcg
     2701 agccgtcccc cgcggagccg ctgggcaacg tggagcgctc gctgcgcggt ccgcccgagc
     2761 tcctgcctga tgcgcgcggc ttcgtgcccg ctggctacga ggagttcgag tacgggggag
     2821 agatcttcgc gctgcccgcg ccctacgacg aggagccctt ccaggcgcca gcgctcttcg
     2881 acaactgctc gccggcctcc tctgagtcca gcctggacat ctgcttcctg cggccggtca
     2941 gtttcgccat ggaggctgag cggccggaac acgcgctaca gccgctgccc aagagcgcta
     3001 cgtcgccggc gagcagcagc ggcgcctaca agctggaggc cgcgcaggcg caggcacacg
     3061 ggaaagccaa gccgctgagc cgctcgctca aggagttccc gcgcacgccg cccgccgagg
     3121 gcgtggcccc gcgcctctac agcacgcgca gcagcagcgg aggccgcgca ccgctcaagg
     3181 tcgagcgtgc tcccgcatcc cacggccccg ctgccgccgc cgccgcctcc cgcggggcgc
     3241 cgcggacctt cttcccccaa cagaggtccc aaagcgaaaa acagacctat ttggaagtaa
     3301 ggagggagat gcacctagag gatgccaccc gattctgtcc aaaggaagaa agagagagtg
     3361 aacagacttc tttcagcgat caaaatccca ggcaagacca gaaagggggc tttcgcagct
     3421 cattccgcaa gctctttaaa aagaagtcca gtggatcaga atacagggaa aaaactaatg
     3481 agaacccctc aatggatcct tcacccacca aacaagattt cttcagaaac cgacttgctc
     3541 ttgcaaatga ccttgaccaa ggaacagctg tgtaaataca tttacagttg tattgtcgag
     3601 tggtaagagg agggtaaaag cttgtatata tctctgtagg aatatatata tatatatctc
     3661 aatgtataaa tccctaagga aaactaatat aaatatttac atatgaaact aaatcaacat
     3721 acaagatact gaagagatga agattagtgt acggttaaga cttggctcta tgaacctcaa
     3781 cacttgggaa aagggaaatg aagactttcc acatcattac agaaaagaaa acatactaaa
     3841 tttggaggaa aataaatgtt tgtaagaaca aa
//
