LOCUS       NM_001106061            3617 bp    mRNA    linear   ROD 24-JUN-2024
DEFINITION  Rattus norvegicus Rho guanine nucleotide exchange factor 3
            (Arhgef3), mRNA.
ACCESSION   NM_001106061 XM_001055379 XM_224588
VERSION     NM_001106061.1
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 3617)
  AUTHORS   Gaudet,P., Livstone,M.S., Lewis,S.E. and Thomas,P.D.
  TITLE     Phylogenetic-based propagation of functional annotations within the
            Gene Ontology consortium
  JOURNAL   Brief Bioinform 12 (5), 449-462 (2011)
   PUBMED   21873635
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH474067.2.
            
            [WARNING] On Mar 20, 2025 this sequence was replaced by
            NM_001106061.2.
            
            On or before Oct 4, 2007 this sequence version replaced
            XM_224588.4, XM_001055379.1.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMD00132261,
                              SAMD00132262 [ECO:0000348]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..3617
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="16"
                     /map="16p16"
     gene            1..3617
                     /gene="Arhgef3"
                     /note="Rho guanine nucleotide exchange factor 3"
                     /db_xref="GeneID:290541"
                     /db_xref="RGD:1310672"
     exon            1..214
                     /gene="Arhgef3"
                     /inference="alignment:Splign:2.1.0"
     CDS             122..1696
                     /gene="Arhgef3"
                     /note="Rho guanine nucleotide exchange factor (GEF) 3"
                     /codon_start=1
                     /product="rho guanine nucleotide exchange factor 3"
                     /protein_id="NP_001099531.1"
                     /db_xref="GeneID:290541"
                     /db_xref="RGD:1310672"
                     /translation="MVAKDYPFYLTVKRANCSLEAPLGSGVAKDEEPSNKRVKPLSRV
                     TSLANLIPPVKTTPLKRFSQTLQRSISFRNESRPDILAPRAWSRNATSSSTKRRDSKL
                     WSETFDVCVSQVLTAKEIKRQEAIFELSQGEEDLIEDLKLAKKAYHDPMLKLSIMTEQ
                     ELNQIFGTLDSLIPLHEDLLSQLRDVRKPDGSTEHVGPILVGWLPCLSSYDSYCSNQV
                     AAKALLDHKKQDHRVQDFLQRCLESPFSRKLDLWNFLDIPRSRLVKYPLLLREILRHT
                     PNDNPDQQHLEEAINIIQGIVAEINTKTGESECRYYKERLLYLEEGQKDSLIDSSRVL
                     CCHGELKNNRGVKLHVFLFQEVLVITRAVTHNEQLCYQLYRQPIPVKDLTLEDLQDGE
                     VRLGGSLRGAFSNNERIKNFFRVSFKNGSQSQTHSLQANDTFNKQQWLNCIRQAKETV
                     LSAAGQAGLLDSESLSQSPGTENRELRGETKLEQMDQSDSESDCSMDTSEVSLECERM
                     EQTDASCANSRPEENV"
     exon            215..322
                     /gene="Arhgef3"
                     /inference="alignment:Splign:2.1.0"
     exon            323..493
                     /gene="Arhgef3"
                     /inference="alignment:Splign:2.1.0"
     exon            494..556
                     /gene="Arhgef3"
                     /inference="alignment:Splign:2.1.0"
     exon            557..653
                     /gene="Arhgef3"
                     /inference="alignment:Splign:2.1.0"
     exon            654..730
                     /gene="Arhgef3"
                     /inference="alignment:Splign:2.1.0"
     exon            731..988
                     /gene="Arhgef3"
                     /inference="alignment:Splign:2.1.0"
     exon            989..1159
                     /gene="Arhgef3"
                     /inference="alignment:Splign:2.1.0"
     exon            1160..1346
                     /gene="Arhgef3"
                     /inference="alignment:Splign:2.1.0"
     exon            1347..3617
                     /gene="Arhgef3"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cgttgtaggt gttcgcgtcg ccgccgccgg catcgtggag ctcgggccct cttttacccg
       61 ggatttttgt tgtcgcctgg gatcagcggt gacatcgcaa agggcaggcc cggcagctgc
      121 catggtggcc aaggattacc ccttctacct cactgtcaag agggcaaact gcagcttgga
      181 ggcgcccctg ggcagcgggg tggccaagga cgaggaacct agtaacaaaa gggtcaaacc
      241 cctttccaga gtcacatcgc tagcaaacct catcccacct gtgaagacca caccgttaaa
      301 gcgcttcagc caaaccttgc agcggtccat cagcttccgc aatgagagcc gccccgacat
      361 cctcgcccct agagcctggt ccagaaatgc cacctcctca agcacgaagc ggagggacag
      421 caaactctgg agtgagacct tcgatgtgtg tgtcagtcag gtgctcacag ccaaggagat
      481 caagagacag gaggcaattt ttgagctttc tcaaggtgaa gaggatttga tagaggactt
      541 gaaattagca aaaaaggcct accatgaccc catgctgaaa ctctcaataa tgacagaaca
      601 agagctgaat cagatttttg gaacactgga ctctctaatc cctctccatg aagacctcct
      661 tagtcagctt cgagatgttc ggaagcccga tggctcgacg gaacacgttg gtcccatcct
      721 cgtgggctgg ctgccttgtc tcagctccta tgacagctac tgcagcaatc aagttgctgc
      781 caaagccctg ctggaccaca agaagcagga ccacagagtg caggatttcc tccagcgctg
      841 cttagaatca cccttcagcc gcaaactcga cctctggaat ttccttgata ttccccggag
      901 ccggctagtg aagtaccctc tgctccttcg agaaatcctg aggcatacgc caaacgataa
      961 tccagaccag cagcacctgg aagaagctat aaacatcatt cagggaattg tggcagaaat
     1021 caacaccaag actggggaat cggaatgccg ttattacaaa gagcggcttc tttacttgga
     1081 agaaggccag aaagattccc tgattgacag ctcaagggtc ctgtgttgtc atggagagct
     1141 gaaaaataac cggggtgtga aactccatgt tttcctgttc caagaagtgc tggtgattac
     1201 tcgagctgtc acgcacaatg agcaactctg ctatcagttg taccggcagc ccatccctgt
     1261 gaaggacctc actctggaag acctgcagga tggagaagtg cggctgggtg gctccctgcg
     1321 tggggccttc agcaacaatg agagaattaa aaacttcttc agagtcagtt tcaagaacgg
     1381 atcccaaagt cagacccact cactgcaagc caacgacacc ttcaacaaac aacagtggct
     1441 caactgtatc cgtcaggcca aagaaacggt tctgtctgct gccgggcagg ctggcttgct
     1501 tgactccgag agcctgtccc agagtcctgg cactgagaac agggagctgc ggggagaaac
     1561 aaaacttgag cagatggacc aatcggacag tgagtcggac tgcagtatgg acacaagcga
     1621 ggtcagcctc gaatgcgagc ggatggaaca gacagacgct tcctgtgcaa acagtaggcc
     1681 cgaggagaac gtctgacaga ggctgtgacc ctgccagcag caggcccgtg tcttacctgt
     1741 acagtgtttg tattccacac gggaacagtt tggagaggca ctttgtaata ctcctgtgcc
     1801 tgtgttggcc tagcccctgt gtctactcct tgtccctagc actgtaactg ccacccagtc
     1861 tgtgtcagct tgcagcagcc cttaccctgt tgctgtatcc cacaagcatc tggatgagtg
     1921 cggaggaatg gaccatgtta cttcgagttg tcctacattc aaaacagaaa gactctctaa
     1981 actactgttg tgcatggcaa ggcctttgtc tcatgcttgc ctagtgttcc tctagctctg
     2041 acatagtcgc tgaagtcctg gcactgggag agctctgcag aatactgaga tcgcattgaa
     2101 gggaaggcag aaagtctgat taacccttgg agggaactcc agttttgagt taattcaact
     2161 agaaagcatg aaaagcatct ctgggggttt ctgaggttgg atttttgcaa aggaggaagc
     2221 cttgttttga agcctgtggt ttcatccagt gcaagttgaa tgtgaataat ctgtgaagac
     2281 ctgaaacaga ggtggcttta gaaagggcca agacaagagc agctgccgga caggcaagca
     2341 gaggcaggaa gatgcggagt tcaagaacag ccttggctac ttaccaaatt ctagttcaaa
     2401 ctgaattcca ccgtaaaaac aaaacaaagc taaaagcacc agccagctct gaatattcag
     2461 ctgaagttgg gggtggatat tggaggcgtt tgtcatggcc aatggcttgc cattagaaga
     2521 gccctttcta gcctacaaca tcaggattgc caggaccaga gaagatctgc cagggtcatg
     2581 tgaccccatc agcattatgt ttcatcctcc tcagccactc ctcttttcca gtggtaatag
     2641 ggggctgggg gatagggaca cagagactgt gactgcatcc agtgactgtt gacaaacaag
     2701 agagaaggac ttgggggtga gaaatgtgtc actgtcaccc aaggctcctg cgtgaaccac
     2761 agaaattgaa gttactccgg agggtctcaa gatttcctgc tctgcttttg ggcctggttc
     2821 tagagctaca gacggactgg tggttaattc ccctcgaggc tggtttcatt agctcttatt
     2881 aactagaacc ggctagccaa actggaaagt tctttgttaa agccttgctt tacagagcaa
     2941 ggatgggtaa aaagaccttg agggcgtggt ggaaaaaacc gttcacaaac tagacagagc
     3001 agcttctgca agtgtaaata cttagaggat ttgtataaaa ttatacccac accagcacta
     3061 gtagtaatga ttctaaatta ttgccaaaaa gttttttttg tttgttgttg ttaatttttg
     3121 catctatcaa aagtttacag aaaagaaagc aaaatgcaaa gttgtccctt tactatgcac
     3181 atgtgtcgtg cgcactgaaa gaagccgtgt ggcaagagca accaatagaa aaacaaggta
     3241 tatgacatta ttatttttca agacctattt tgaccagttt ctaccctgta aagcctattt
     3301 ctgtatttat agtttttaac catggtgaaa atttttttct attatgagtt tatttaaaac
     3361 cattttgtct ctcaagttgc tgatgtagcg aataaacctg ctccgggcag acacagtagg
     3421 aagctgagac ggaccgggca ctggacgata gagaaaagcc tgaaatgttc tctacagagc
     3481 cattgtgacc agcgagttaa ggaagggtct ctgtcagggt cagcctgtgg gaagagagtg
     3541 aatgaatgtt ctggtgaaat gaatactttt gtataatggc cttaaacttt tctggaagca
     3601 tttcaaataa attgcat
//
