LOCUS       XM_227201               4403 bp    mRNA    linear   ROD 11-JUN-2023
DEFINITION  PREDICTED: Rattus norvegicus Rho guanine nucleotide exchange factor
            26 (Arhgef26), mRNA.
ACCESSION   XM_227201
VERSION     XM_227201.10
DBLINK      BioProject: PRJNA677964
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_051337.1) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            [WARNING] On Feb 2, 2024 this sequence was replaced by
            NM_001427682.1.
            
            On Jan 21, 2021 this sequence version replaced XM_227201.9.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_015227675.2-RS_2023_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.1
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/06/2023
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4403
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN/NHsdMcwi"
                     /db_xref="taxon:10116"
                     /chromosome="2"
                     /sex="male"
                     /tissue_type="kidney"
                     /geo_loc_name="USA: Wisconsin, Milwaukee, Medical College
                     of Wisconsin"
                     /collection_date="2019-03-08"
                     /collected_by="Rebecca Schilling"
     gene            1..4403
                     /gene="Arhgef26"
                     /note="Rho guanine nucleotide exchange factor 26; Derived
                     by automated computational analysis using gene prediction
                     method: Gnomon. Supporting evidence includes similarity
                     to: 1 mRNA, 12 ESTs, 5 Proteins, and 100% coverage of the
                     annotated genomic feature by RNAseq alignments, including
                     83 samples with support for all annotated introns"
                     /db_xref="GeneID:310460"
                     /db_xref="RGD:1562559"
     CDS             1..2610
                     /gene="Arhgef26"
                     /codon_start=1
                     /product="rho guanine nucleotide exchange factor 26"
                     /protein_id="XP_227201.4"
                     /db_xref="GeneID:310460"
                     /db_xref="RGD:1562559"
                     /translation="MDGESEVDFSSNGVTPLWRRRSTPPLQLLGRSKPRPQSYQSPSG
                     LLITDFPVEELAALPAPQTPVPVPAGPEGRTVSRSPQLLCAHRRPVTNGRTVSPDYRA
                     ASPRLRRPKSPLVSYAASGGSPKSAVNGTVSSPAALLSRASRTPDIPASSAPGEDRTR
                     VTASKVSSPTANGLAPKTDSSGPVSQTGQSAGDLEPSPSRLSPAPQHRSSEQKLPLQR
                     LPSQGNELPNPSVILSTNSPAALKMGKQQIIPKSLASEIKLSKSNSQNVEPHRRLLKV
                     RSMVEGLGAPLGPEGEESEADNDIDSPGSLRRGLRSTSYRRAVVSGFDFDSPTSSKKK
                     NRMSQPVLKAVMEDKEKFSSLGRIKKKMLKGQGTFDGEENAVLYQNYKEKALDIDSDE
                     EPEPKEQKPEEKIVIHHKPLRSTWSQLSAVKRNGLSQTVSQEERKRQEAIFEVISSEH
                     SYLLSLEILIRMFKDSKELTDTMTKTERHHLFSNITDVWEASKKFFTELEARHQNNIF
                     IEDISDIVEKHTASTFDPYVKYCTNEVYQQRTLQKLLTTNPSFKEVLSRIESHEDCRN
                     LPMISFLILPMQRVTRLPLLMDTICQKTPKDSPKYEVCKRALKEVSKLVRLCNEGARK
                     MERTEMMYTINSQLEFKIKPFPLVSSSRWLVKRGELTAYVEDTVLFSKRMSKQQVYFF
                     LFNDVLIITKKKSEESYNVNDYSLRDQLLVESCDNEELNSSPGKNTSTMLYSRQSSAT
                     HLFTLTVLSNHANEKVDMLLGAETQSERARWITALGHSSGKQPPDRTTLTQVEITRSF
                     TAKQPDELSLQVADVVLIYQRVGDGWYEGERLRDGERGWFPMECAKEITCQATIDKNV
                     ERMGRLLGLETNV"
ORIGIN      
        1 atggacggcg aaagcgaggt ggatttttcc agcaacggcg tcaccccttt gtggcggaga
       61 cggtctaccc ctccgctcca gttgctcggc cggagcaagc cgcggccaca gtcgtaccag
      121 agccccagcg ggctgctgat cactgacttc ccggtggagg agctagctgc tctgcccgcg
      181 ccacagactc cggtccctgt acccgccggc ccagagggca ggacagtgtc caggagcccc
      241 cagcttctgt gcgcacatcg gaggccggtg accaatggtc gcacggtgtc cccggactac
      301 agagctgctt ctcctcgact tcgacgaccc aagtcacccc tggtttccta cgcggcgtct
      361 ggaggctccc cgaagtccgc tgttaatggc acggtgtcct cgcccgcggc gctgttgtcg
      421 cgcgcctcgc ggactccgga catcccagcc tctagcgccc cgggtgagga ccgcaccagg
      481 gtgactgcca gtaaggtatc ttcacccact gcgaatggcc ttgccccgaa aaccgactca
      541 tctggcccag tatcacaaac tggtcagtct gctggggact tggagccgtc cccctcgaga
      601 ctctctcctg ccccccagca caggtcttca gaacaaaaac tgcccctcca aaggctgccc
      661 tcccaaggga atgagctacc gaacccttcc gtgattttga gtaccaacag cccggcggcc
      721 ctcaagatgg gaaagcagca gattatcccc aaaagccttg cctccgaaat taaactgagt
      781 aaatccaaca gtcagaatgt agagccccac aggaggcttc tcaaggtgcg cagcatggtg
      841 gagggactgg gagcacccct gggccccgaa ggggaggaaa gcgaagccga caacgacata
      901 gacagcccgg gctcccttcg gcgaggcttg cggtccacat cttaccgaag ggcagtggtc
      961 agcggttttg attttgacag tcccaccagc tcaaagaaga agaacagaat gtcccagcct
     1021 gtcctgaagg cggtaatgga agacaaggag aagttctcta gcttgggaag gataaagaaa
     1081 aaaatgctga aaggacaagg aacatttgat ggagaagaaa atgcagtcct gtatcagaac
     1141 tacaaagaaa aggcccttga catcgactct gatgaagaac cagagcccaa ggaacagaag
     1201 ccagaggaga aaattgtgat tcaccataag ccactgagat ctacatggag ccagctctcc
     1261 gcggtgaaaa gaaatgggct atctcagaca gtgagccagg aggagagaaa gagacaggag
     1321 gcaatctttg aagtcatatc gtcagagcac tcctacttac tcagcttgga gatcttgata
     1381 cggatgttta aagactctaa agaactgact gatacaatga ctaagacaga gaggcatcac
     1441 cttttctcca acattaccga tgtctgggag gccagcaaaa aattcttcac ggagttggaa
     1501 gcaagacacc agaataacat cttcatagag gatataagtg acattgtaga aaagcacaca
     1561 gcctccacgt ttgatcccta tgtgaaatac tgcaccaatg aagtctacca acagcgaacg
     1621 ctgcagaagt tgttaacaac caacccctcc tttaaggaag tgttgtcgag gattgagtcc
     1681 catgaggact gcaggaactt acctatgatc tcttttctca ttctccctat gcagagggtg
     1741 acacgccttc ccctgctgat ggatactatc tgtcagaaaa cacccaagga ctctccaaag
     1801 tatgaggtct gcaaaagggc cttgaaggaa gtgagcaagt tggtgcgact gtgcaatgaa
     1861 ggagcgcgga agatggagag gacggaaatg atgtacacga ttaattccca gctggaattt
     1921 aaaattaagc ctttccccct ggtctcctct tcccggtggt tggtgaaaag aggggagttg
     1981 acagcctacg tggaagacac agtgctgttc tcaaagagga tgtccaagca gcaggtctac
     2041 ttcttcctgt tcaatgatgt gcttatcatc actaagaaga agagcgaaga aagctacaac
     2101 gtcaatgatt actccttacg ggaccagttg ctggtggaat cctgtgacaa tgaggagctc
     2161 aattcttctc cagggaagaa cacgtccacg atgctttact ccagacagag ctctgccact
     2221 cacctcttta ccctgaccgt cctcagcaat catgccaatg agaaggtgga catgctgctt
     2281 ggggcagaga cccagagtga gcgagcccgt tggatcacag ccctgggaca cagcagtggg
     2341 aagcagccac cagacagaac cacactgacc caggtggaaa tcactaggtc ttttactgcc
     2401 aaacagccag atgaactgtc cctgcaggtg gcagatgtgg tcctcattta tcagcgtgtt
     2461 ggcgatggct ggtatgaagg ggaacgactc cgagatggag agcggggctg gtttccaatg
     2521 gaatgtgcaa aggagataac atgtcaagct actattgata agaatgtgga aaggatggga
     2581 cgcttgctag gactggaaac caacgtgtaa cctctcagac ggccaataga acagggctac
     2641 ttttacatta caatctgctt aattaaaaag tggaaacact tgcctataag cttgccaagc
     2701 caccctgcac tttggaagaa cggctcccag atgcagttag ccctcaaagc tcagcttttg
     2761 cataatgaac atccactcaa caggctacta cttcagcgat gacaagtgtt ggtgtgtttt
     2821 ctaagatgct gtatcttggc ctctctgccc ccagttcacg cagaaagttg ctcttcccca
     2881 tgagtttctc tttggtatgg tcccacagca tcagcaagtt tgtctttgag tgtccatttt
     2941 gtaaatactt tttgtgtctt agcctaatgt tgttaattcc aaaaggaact aataataggt
     3001 aggtgagctg tcatgttttg taaacctctt tctgcgaaag ggaaattgac acttgaactc
     3061 tgccaccatt ttccttatta gaaggaaggt gaggagccac ccggtgagga tttttaaaaa
     3121 tccatctcat tcaatgttgg tcttaggtaa ctatagcatc gcaaccctaa actactaaag
     3181 tgacatggga tttacagctc atggatgtga gagcatcctg aagacaggat attacgggtc
     3241 cactgctaaa gagctgacta agattgctct gcctccagtg acacatggtt cctgacaatt
     3301 ctgcttgttt tcaattgaaa atggctggaa catatattaa caatcttcag aaagagaaaa
     3361 ttaagcctag gcagtatcaa gatgccaaca aggtacttgc ttgaaatacg ttgaagctag
     3421 cagaaattca ttgcattcaa tacctggtag atgggtttgg agtttgtttt tccactagga
     3481 caaagagaga aaatgtggta taatgcagtt tattaaaagg taatgaaggt ttcgaagaca
     3541 tgggaaatgt tttcattggt aactatgatc cctttattct gttcaccaag taaaatctat
     3601 acagacatta gcaggctcaa atctttgtcc cacgtcccta ctcctgtcta aacagcacct
     3661 acacagtaag tttccagaag cccagtgtgt aggtgtgcgt ggctcatatc ctgcaaccca
     3721 tccacctcag cagtaaacag gagtggggct cccaggcact tcttaccttt gggttgcctt
     3781 ccttttgcct gtgtatgtat tccttgcaaa agacattcca gtccttggag gtaagagtta
     3841 agtacatgaa tgaagcaaca gcagtagccc acagcacgag atgtcccagg ataataaaac
     3901 aggaaatctt gtgtactaac aagttgtagt ttaatatgtt ttacttgagg cagatggtgt
     3961 tgcttgaaag aggagtcatt ttgtattatt ttttgctaat acccatttgg agctataaag
     4021 taatactatg aatcctgtga attaatttat aagtgttaaa cagtgtggaa atatatgcat
     4081 cctttcagtc aagcagctga acactgttat aaaagtgttc ctgtagagca ggtatttaac
     4141 agtcacagcg tttcatttca actgtgattg ttttgaacat ttttatgtct tctttgaaat
     4201 gtacaatgat ttcactcctg caaaaacaga aatgttactt ttgttccaat aaattgaaac
     4261 tgcttgtata ctttcaacaa agcctgtgaa tttataaaga ctttatatat acgtgtcttt
     4321 ctgtgccagt gtgattgatt tacttgtggt gtgaagttta tggcctgggg atctgtggtt
     4381 aaataaaagc tatactgaag tta
//
