LOCUS       NM_001108692            3648 bp    mRNA    linear   ROD 24-JUN-2024
DEFINITION  Rattus norvegicus Rho guanine nucleotide exchange factor 19
            (Arhgef19), mRNA.
ACCESSION   NM_001108692 XM_001072580 XM_342965
VERSION     NM_001108692.1
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 3648)
  AUTHORS   Caddy,J., Wilanowski,T., Darido,C., Dworkin,S., Ting,S.B., Zhao,Q.,
            Rank,G., Auden,A., Srivastava,S., Papenfuss,T.A., Murdoch,J.N.,
            Humbert,P.O., Parekh,V., Boulos,N., Weber,T., Zuo,J.,
            Cunningham,J.M. and Jane,S.M.
  TITLE     Epidermal wound repair is regulated by the planar cell polarity
            signaling pathway
  JOURNAL   Dev Cell 19 (1), 138-147 (2010)
   PUBMED   20643356
  REMARK    Erratum:[Dev Cell. 2010 Aug 17;19(2):353. Parekh, Vishwas [added]]
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH473968.1.
            
            On or before Oct 4, 2007 this sequence version replaced
            XM_342965.3, XM_001072580.1.
            
            ##Evidence-Data-START##
            RNAseq introns :: partial sample support SAMD00132261, SAMD00132275
                              [ECO:0000350]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..3648
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="5"
                     /map="5q36"
     gene            1..3648
                     /gene="Arhgef19"
                     /note="Rho guanine nucleotide exchange factor 19"
                     /db_xref="GeneID:362648"
                     /db_xref="RGD:1304766"
     exon            1..269
                     /gene="Arhgef19"
                     /inference="alignment:Splign:2.1.0"
     exon            270..382
                     /gene="Arhgef19"
                     /inference="alignment:Splign:2.1.0"
     CDS             313..2979
                     /gene="Arhgef19"
                     /note="Rho guanine nucleotide exchange factor (GEF) 19"
                     /codon_start=1
                     /product="rho guanine nucleotide exchange factor 19"
                     /protein_id="NP_001102162.1"
                     /db_xref="GeneID:362648"
                     /db_xref="RGD:1304766"
                     /translation="MCPLWYLPSSRRGPGGPPRRAALESVPKLLSLRPPFLWVSLLFL
                     PDWALPLWPQGPLQGSSLPRLSTAQPGKCPGGWQRKGGMDCGPPATLQPHLAGPPGTA
                     RRPVAVCQQESLSFVELPTLHPPSPVCVDLFPITPEELQAPGSRWSLATPAPLQGLLW
                     PTSSGGPDTHISTTGGMRPSRAGSWPHCPGAQPPTLVGPWSSQHMQPQRRASHGGSEK
                     SAWRKMQVYHNEEATGGTEPPMGLLETGQAVQGQALCAQEPRPQELSGNTRGGLEAQE
                     RRRFSASELMTRLHSSLRLGRSTAPRALTSGSGAGVIREGKLPGREPRRAETRMDSVS
                     LPAPVDLNEVQGGLVEPRLDTNDKPTQDTNSATERRQSRFLLNSVLYQEYSDVASARE
                     LRRQQREEEGPGDGAEGAEEGPGPPRANLSPSSSFRAQRSTRGSTFSLWQDIPDVRGS
                     GVLATLSLRDCKLQEAKFELITSEASYIHSLSVAVGHFLGSVELSECLGTQDKQWLFS
                     KLPEVKSTSERFLHDLEQRLEADVLRFSVCDVVLHHCPAFRRVYLPYVTNQAYQERTY
                     QRLLLENPKFPGILARLEESPVCQRLPLTSFLILPFQRVTRLKMLVENILKRTTPGSQ
                     DEDMATKAFSALKELVQECNASVQSMKRTEELIHLSKKIHFEGKIFPLISQARWLVRH
                     GELVELAPLPAAPPAKLKLSSKAVYLHLFNDCLLLSRRKELGKFAVFVHANMAELQVR
                     DLSLKLQGIPGHVFLLRLLHGQRARHQLLLRARTESEKQRWISALRPSSPQEDKEITC
                     DGEDRPQVQCVRTYKALQPDELTLEKTDILAVKTRTSDGWLEGVRLADGEKGWVPQAH
                     VEEISSLSARLRNLREYKRVSNVSSKLGDPPA"
     exon            383..529
                     /gene="Arhgef19"
                     /inference="alignment:Splign:2.1.0"
     exon            530..973
                     /gene="Arhgef19"
                     /inference="alignment:Splign:2.1.0"
     exon            974..1258
                     /gene="Arhgef19"
                     /inference="alignment:Splign:2.1.0"
     exon            1259..1367
                     /gene="Arhgef19"
                     /inference="alignment:Splign:2.1.0"
     exon            1368..1444
                     /gene="Arhgef19"
                     /inference="alignment:Splign:2.1.0"
     exon            1445..1707
                     /gene="Arhgef19"
                     /inference="alignment:Splign:2.1.0"
     exon            1708..1868
                     /gene="Arhgef19"
                     /inference="alignment:Splign:2.1.0"
     exon            1869..2021
                     /gene="Arhgef19"
                     /inference="alignment:Splign:2.1.0"
     exon            2022..2151
                     /gene="Arhgef19"
                     /inference="alignment:Splign:2.1.0"
     exon            2152..2226
                     /gene="Arhgef19"
                     /inference="alignment:Splign:2.1.0"
     exon            2227..2316
                     /gene="Arhgef19"
                     /inference="alignment:Splign:2.1.0"
     exon            2317..2477
                     /gene="Arhgef19"
                     /inference="alignment:Splign:2.1.0"
     exon            2478..2636
                     /gene="Arhgef19"
                     /inference="alignment:Splign:2.1.0"
     exon            2637..2716
                     /gene="Arhgef19"
                     /inference="alignment:Splign:2.1.0"
     exon            2717..2821
                     /gene="Arhgef19"
                     /inference="alignment:Splign:2.1.0"
     exon            2822..3648
                     /gene="Arhgef19"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gagcgtgagc ctggatgggg tgaggctctg tctacagtgg aagaacctag ctggaaccgc
       61 aggaagctga gtctgtttag tacacagctg atcagagtcg gctgggttga agccgcagga
      121 ccaacttcta agggagggaa gggcaggagt gcagagcccg gagtccacat ccgagacccc
      181 taagtcaaag acatttcaac taccctcaac tcaccctcaa ctactggaaa aatgctggcc
      241 acgcatctgg cttcgtcatc cccttggagt tccttctgat ctccctgcct ttggcagcct
      301 ggctccagtg gaatgtgccc gctgtggtac ctaccaagtt caaggagagg tcctggcggt
      361 ccaccaagac gcgctgcttt agagtcggtt cctaagctgt tgtctctaag gccgccattt
      421 ctttgggtct ccctcttatt tctgccagac tgggcactgc ccctttggcc ccaggggcct
      481 ctgcaggggt cctcgctgcc caggctgtcc acagcacagc caggcaagtg cccgggaggg
      541 tggcagagga aaggaggaat ggactgtgga ccacctgcaa ccctccagcc tcacctggct
      601 ggaccacctg gcactgcccg tcgcccagta gccgtgtgcc agcaagagag cctgtccttt
      661 gtggagctgc ccaccctgca ccctccaagc ccagtgtgtg tggacctctt tcccattact
      721 ccagaggagc tacaagcccc tggtagccgc tggtccctgg cgacccctgc ccctctccaa
      781 ggactgttat ggccgacatc ctcaggaggc ccagataccc atatctccac cactggagga
      841 atgaggccca gcagggctgg cagctggcct cactgtcctg gtgcccagcc cccaactctg
      901 gtgggaccct ggagttctca gcatatgcag ccccaacgaa gggccagcca cggtggctca
      961 gagaagtcag cctggcgcaa gatgcaggtg tatcataacg aagaggccac aggcggcaca
     1021 gagcccccca tgggccttct ggagactggc caggctgttc aagggcaggc tctgtgtgcg
     1081 caagagcccc ggccacagga actttctggg aacaccagag ggggccttga ggcacaggag
     1141 agaagacgtt tctcggcctc agagctgatg actaggctgc attcttctct ccgtttgggg
     1201 cgcagcacgg cccctagagc tctgacctcg ggctcaggtg ctggagtcat ccgggaaggg
     1261 aaactgcccg ggagggaacc ccgaagagcc gagacgagga tggacagtgt gtccctgcca
     1321 gcacccgtcg atctaaatga ggtccagggt ggtctggtgg agcccaggtt ggacacgaac
     1381 gacaagccga ctcaagatac caacagtgcc actgagcgac gccagtcccg tttcctcctt
     1441 aactctgtcc tctaccagga gtacagcgac gtggccagcg cgcgcgaatt gcggcggcag
     1501 cagcgcgagg aggagggccc cggggacggg gcggagggcg cggaggaggg gcccgggcca
     1561 ccgcgcgcca acctctcccc gagcagctct ttccgcgcgc agcgctcgac gcgaggctcc
     1621 accttctcgc tgtggcagga catccccgac gtgcgcggca gcggcgtcct ggccacgctg
     1681 agcctgcgcg actgcaaact gcaggaggcc aaatttgagc tgattacctc ggaggcctcc
     1741 tacatccata gcctgtcggt ggccgtgggt cacttcttag gttccgtgga gctgagcgag
     1801 tgtctgggga ctcaggacaa acagtggcta ttttccaaac tccccgaggt caagagcacc
     1861 agtgagagat ttcttcacga cctggaacag cgtctggagg ccgacgtgct gcgcttcagc
     1921 gtctgtgatg tggttctgca ccactgcccc gccttccgcc gggtctacct gccctacgtc
     1981 accaaccagg cctatcagga gcgcacctac cagcgcctgc tcctagagaa ccccaagttc
     2041 cccggcatcc tggctcgctt agaggagtct cctgtgtgcc agcggctgcc tctcacctca
     2101 ttcctcatcc taccgttcca gagggtcacc cgcctcaaga tgctggtgga gaacatcttg
     2161 aagcgcacga caccgggctc ccaagatgag gacatggcta ccaaggcctt cagtgcacta
     2221 aaggagctgg tgcaggaatg caacgcaagc gtgcagtcca tgaagaggac cgaggagctc
     2281 attcacctga gtaagaagat ccacttcgag ggcaagatct tcccgctgat ctcacaggcc
     2341 cgctggctgg tacggcacgg ggagctggtg gagctggccc cgctgcccgc cgcaccacca
     2401 gccaagctga agctgtccag caaggctgtg taccttcacc tcttcaatga ctgcctgctg
     2461 ctgtcccgga ggaaggagct cgggaagttt gccgtatttg ttcatgccaa catggctgag
     2521 ctacaggttc gagacctcag cctgaagctc cagggcatcc ccggccatgt attcctgctc
     2581 aggctgctgc atgggcagcg cgccaggcac cagctgctgc tgagggcacg gacagaaagc
     2641 gagaagcaac ggtggatttc ggccttgcgt ccatccagcc cccaggaaga caaggagatc
     2701 acttgtgatg gggaagaccg cccccaggtc cagtgtgtga ggacttacaa ggccctgcag
     2761 cccgatgaac tgaccttgga gaaaacagac atcctagcag tgaagactag gaccagcgat
     2821 ggctggctgg agggtgtgcg actggccgat ggtgagaagg ggtgggtgcc tcaggcccac
     2881 gtggaggaga tcagcagcct cagcgctcga ctgcgtaacc tccgggagta caagagggtc
     2941 tccaacgtca gcagcaagct gggggacccg cccgcctgat gctccgctgg ggccactctg
     3001 gtgctggtgg gcttctgtgt gtctgagggc cgcagggtgg caacggttct gtaaatacac
     3061 tctggctgcc tctgctcagt ctgagcgggg cgggccttct catgggctgc cccatcagga
     3121 gggcactggt tgttcctgct gtcactcgtc ccaagggcag aggggctgcc ccaacctgct
     3181 actttcccct ccaagtagca agtgtcagat ccaagcaggc ttgaatatta aagtgactcc
     3241 gtgagtttct gtagttgcct cttgtggcct gtgccaagaa agcaccacca gctggggggt
     3301 agccttgaaa ctattaaagc atagctcaga ggccaggctc tcaaatcggc ctcctgggct
     3361 gggctccagg tggaggtgat gctgggcccc atctgggtct caggagaaaa tcgcttgttg
     3421 cctctgtgta cttggtggtt gccagtgagc tgcacttgca gacaaatccc agtcctactg
     3481 tgtgtcctct gtctgcccgg gactgtgagc ctatggcttc atttggagtc tcccccaccc
     3541 accctcaacc atctccccat cacagtcctg gaaaaaacat cgacaaacat acttcttccg
     3601 tgttttcttg ttttgttttg cttatttgtt taaaaacctt tttaaatg
//
