LOCUS       XM_039100295            5744 bp    mRNA    linear   ROD 11-JUN-2023
DEFINITION  PREDICTED: Rattus norvegicus Rho GTPase activating protein 6
            (Arhgap6), transcript variant X4, mRNA.
ACCESSION   XM_039100295
VERSION     XM_039100295.1
DBLINK      BioProject: PRJNA677964
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_051356.1) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            [WARNING] On Feb 22, 2024 this sequence was replaced by
            XM_039100295.2.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_015227675.2-RS_2023_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.1
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/06/2023
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5744
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN/NHsdMcwi"
                     /db_xref="taxon:10116"
                     /chromosome="X"
                     /sex="male"
                     /tissue_type="kidney"
                     /geo_loc_name="USA: Wisconsin, Milwaukee, Medical College
                     of Wisconsin"
                     /collection_date="2019-03-08"
                     /collected_by="Rebecca Schilling"
     gene            1..5744
                     /gene="Arhgap6"
                     /note="Rho GTPase activating protein 6; Derived by
                     automated computational analysis using gene prediction
                     method: Gnomon. Supporting evidence includes similarity
                     to: 5 ESTs, 4 Proteins, and 100% coverage of the annotated
                     genomic feature by RNAseq alignments, including 15 samples
                     with support for all annotated introns"
                     /db_xref="GeneID:100363276"
                     /db_xref="RGD:2323364"
     CDS             2040..4427
                     /gene="Arhgap6"
                     /codon_start=1
                     /product="rho GTPase-activating protein 6 isoform X4"
                     /protein_id="XP_038956223.1"
                     /db_xref="GeneID:100363276"
                     /db_xref="RGD:2323364"
                     /translation="MYRIFGDFTWNSMSGRSVRLRSVPIQSLSELERARLQEVAFYQL
                     QQDCDLGCQITIPKDGQKRKKSLRKKLDSLGKEKNKDKEFIPQAFGMPLSQVIANDRA
                     YKLKQDLQREEQKDASDFVSSLLPFGNKKQNKELSSSNSSLSSTSETPNESTSPNTPE
                     PAPRARRRGAMSVDSITDLDDNQSRLLEALQLSLPAEAQNKKQKARDKKLSLNPIYRQ
                     VPRLVDSCCQHLEKHGLQTVGIFRVGSSKKRVRQLREEFDRGVDVCLEEEHSVHDVAA
                     LLKEFLRDMPDPLLTRELYTAFINTLLLEPEEQLGTLQLLIYLLPPCNCDTLHRLLQF
                     LSIVARHAEDNVSKDGQEVTGNKMTSLNLATIFGPNLLHKQKSSDKEYSVQSSARAEE
                     STAIIAVVQKMIENYEALFMVPPDLQNEVLISLLETDPDVVDYLLRRKASQSSSPDML
                     QSEVSFSMGGRHSSTDSNKASSGDISPYDNNSPVLSERSLLAMQEDRARGGSEKLYKV
                     PEHYTLLDHLPSPKSKSRESSPGPRLGKDMSEEPFNIWGTWHSTLKSGSKDPGMTGSY
                     GDIFESSSLRPRLCSLSQGNLSLNWPRCQGSTTGMDSGTQVIRRTQTAATVEQCNVHL
                     PVSRVCSTPHIQDGGRGSRRPAARSEPFLSLNSTEDLAEGKEDVAWLQSQAQAVYQRP
                     QESGRDDRRPPPPYPGSGKPATTSAQQPLEPPLWRLQRQEEGSETVVEEGGQQASGEH
                     QTRPKKLSSAYSLSASEQDKQNLGEASWLDWQRERWQIWELLSTDNPDALPETLV"
ORIGIN      
        1 accgggaaag ggaataacac tcgaaatgta tataagaaat agtcaagtta ataaaaaaaa
       61 aaaaagaagc atgtcagaca tggttctgga aaggtacctg agagtaccac agcatgagct
      121 gaaggcagga ggagactgtg tgccacactg ggtgtagttt gagaatatca aacgtcaaaa
      181 ccgtctccac agtgacacac ttgttccagc aaggccacac ctactccaac aaggccacac
      241 cttctagtag tgccatttgc catgggccaa gcgttcaaat acatgagtct atggggatca
      301 ttgattttca aatcaccaca ctaacatcac taatttagtg aatttctttg atttatataa
      361 gatggaatta aaactgccat ccatattcta agaagtattt atagatgata cagtcttcct
      421 atgagtgagt ctttatttta taggccaatt gaaagataat tctcagtcat ttattttaag
      481 aaatcctctc aaatcttcta tcactcgatt tcatactgcc catgggtcgc agactatttc
      541 atacttaggt atgattaact aagaaaacta gaatgcaaag ctgagatatc attcactcag
      601 tagtcttgtc tccagggcct tttgtaaggt ttttaaatta atgtagacgg gtttgtcctg
      661 cttctgctga atgcactgat cctttcccac gtggtatggg ttaattataa ccaatgcttt
      721 gtttgctttt gttagcagtg ctgatttcag tttcctaggc agcagatatc tcctaccaaa
      781 ttacaatctg ctacccaaac atcagtattg cctctgtttc attattatta ttgtttgtgt
      841 aggaaaactg ttagaatctg tagttcaccc gagttgtacc aaacaatcta tttgctatgg
      901 atgagagcaa tatcctttgt agacattcat cccatacatt taggaagaca tttatattat
      961 tattgagtat cttggctggt ttaaatatga tgttcctaag gttcgaggct aatgttggtt
     1021 acaacatttt caccaaattt tatctggtta ttgtactgat gtaattttag tctgaaccaa
     1081 ttgagaattg acaacgagta taaatcagta cctagatgag aacaaaagtt atagcataga
     1141 agtagggact gagtcatagt tgatctcttt ttttttattt tttttatagt tgatcttttt
     1201 tacaacaatg atgtcaattc tgcattaatg acaatacact tgcatgaagc accatataat
     1261 gaagtgtgca gctatgttgt gcagtgtgtg tgtacgtgtg tgtgtgtgtg tgtgtgtgtg
     1321 tgtgtgtgtg tgtgtgtgtg tgcgtgcgtg cgtgtgtgtg tgtagaactg atctatttct
     1381 atattaacat tgtcaggaaa aatacaccca ttctttgcca tggagcatat tgtgtgttga
     1441 gttttgaatt tattttacac ttgtctgtgt tattttactg caattcttat ctaaacattt
     1501 ccagaaaaag aaaggtgagg attgatttgt caatgcctga ggcctttccc aacttgtggc
     1561 tgaaacccat gcttgacagt gagttgttta agcctcgaaa ggaattttcc cacagaaagg
     1621 atgttctaat tggcaggatc ccaggaccgc ccacaaatcc atttaaccat aacagagctg
     1681 accaacagca ctgtcagggc tagagttcgt ttccaagtgg gaagtcagcc tagtattaat
     1741 agcacagttc cagctgaact gcaggcccag tggacttctg atgggtcggc ctgggaacca
     1801 aggcaatctt tgtaacactt atgggaaatg gattccttgg tgagaatggt gggaagaaag
     1861 tccggcagag gcagaggaac atgacttccc attttccctt ttcactctaa ttattaccaa
     1921 ctccagtatc cagtgagaag agaccagggt gactcctagg ggaacacttc cctcaacttg
     1981 aaatctagag agagcctgct ctgtgttgct gatctgattg tgtcggattg actgttccca
     2041 tgtacagaat atttggtgac ttcacctgga acagcatgtc tggccgtagt gtgcgcctga
     2101 gatctgtccc tatccaaagc ctctcagagc tggagcgggc acggctgcag gaagtggctt
     2161 tttatcagtt gcagcaggac tgtgacctgg gctgtcagat caccattccc aaagatggac
     2221 aaaagagaaa gaaatctttg agaaagaaac tggattcgct agggaaggaa aagaacaaag
     2281 acaaagaatt catcccacag gcatttggaa tgcccttatc ccaagtcatt gctaatgacc
     2341 gggcatataa actgaagcaa gatttgcaga gggaggagca gaaggatgca tcggattttg
     2401 tgtcttcgct cctcccattt gggaataaaa aacaaaacaa agaactctca agcagtaact
     2461 catctctcag ctcaacctca gaaacaccaa atgagtctac atccccaaac actccagaac
     2521 cagctccccg ggccaggaga aggggtgcca tgtccgtgga ttccatcaca gatctggatg
     2581 acaaccagtc tcgactccta gaagctttac aactctcctt gcctgctgag gctcagaata
     2641 aaaaacaaaa ggccagagat aagaagctga gtctgaatcc tatttacagg caggttccca
     2701 ggctagtgga cagctgctgt cagcatctgg aaaaacatgg cctccagacc gtggggatat
     2761 tccgagttgg aagctcaaaa aagcgagtaa gacaattgcg tgaggaattt gaccgtgggg
     2821 ttgatgtctg tctggaagag gagcacagtg ttcatgatgt ggcagccttg ttaaaggagt
     2881 tcctcagaga catgcctgac ccccttctca caagggagct atacactgca tttatcaaca
     2941 ctctcttgtt ggagcctgag gaacaactgg gcaccttgca actcctcatc taccttctac
     3001 ctccctgcaa ctgcgacacc ctccaccgcc tcctacagtt cctctccatt gttgccaggc
     3061 atgctgaaga taatgtcagc aaagatggac aagaggtcac tgggaacaaa atgacatctc
     3121 tgaacttggc taccatattt ggacccaacc tgctccacaa gcagaagtca tcagacaaag
     3181 aatattctgt ccagagctca gccagagctg aagagagcac agccatcata gctgtggtac
     3241 agaagatgat tgaaaattat gaagccctct tcatggttcc cccagatctc cagaatgaag
     3301 tgctgatcag ccttctggag acagatccgg atgttgtgga ctacctgctc agaagaaagg
     3361 cttcccaatc ctcgagccct gacatgcttc agtcggaagt ttccttttcc atgggaggga
     3421 ggcattcatc tacagactcc aacaaggcct ccagtggaga catctcccct tatgacaaca
     3481 actccccagt actgtctgag cgctccctgc tggctatgca agaagacagg gcccgggggg
     3541 gctcggagaa gctttataaa gtgccagagc attatacact gttggaccac ttgccatcgc
     3601 caaagtcgaa gtcaagagaa agttctcctg gaccaaggct tggaaaagat atgtcagagg
     3661 agcctttcaa tatctgggga acttggcatt caacattaaa aagcggatcc aaagacccag
     3721 gaatgacagg ttcctatggt gacatttttg aaagcagctc cctccgaccg aggctgtgtt
     3781 ccctctctca agggaaccta tccctgaatt ggcctcggtg tcaagggagc accacaggaa
     3841 tggacagtgg cactcaggta attcggagga ctcagacagc ggccaccgtg gagcagtgca
     3901 atgtccacct tccggtgtca cgtgtctgca gcactcccca catccaggac ggcggcaggg
     3961 ggtccaggcg gcctgcagcc aggtctgagc catttttgtc cttaaacagc acggaagacc
     4021 tggccgaggg caaggaggat gtggcctggc tgcaaagcca ggcccaagcc gtgtaccaga
     4081 gacctcagga gagtggtaga gatgacaggc gcccccctcc accttaccca gggtcaggga
     4141 agcctgccac gacctcggcc cagcagccac tagagcctcc cctgtggagg ctccagaggc
     4201 aggaagaagg ttcagaaaca gttgtggaag aaggaggcca gcaggcctca ggggaacatc
     4261 agaccaggcc aaaaaaactg agcagcgcct actccctctc agccagtgag caggacaagc
     4321 agaacttagg ggaagccagc tggctcgact ggcagcgaga gcggtggcag atctgggagc
     4381 tcttgtcgac tgacaacccc gatgccctcc cggaaaccct agtataagcc cgccagcagc
     4441 tggagcccac ccttccaaaa aacatcttcc ggcccagacc cggaaactat ggacaattgg
     4501 acacttactc gtttttcttt ttgtttttcc acattttgaa aaagtaacac aagagaaagt
     4561 ccacttccag attcacttct acccttgcca tttatggtaa gactctattg catagccagc
     4621 cttagaaaaa gcaaacaaac atgacaattc ccaatctaaa aacccacatt ggctttatgt
     4681 aaaatcaaac tcttgctttg ttatagctta agtgtattta tgtgtcttca attttggcta
     4741 ttgtgtattc tgtaacaaat tatgtatatc aatatgatat tcacagagaa gacagaacaa
     4801 ttagaaaaaa tcactgcact tatattacac tttgagatat attaagcaac cagattctat
     4861 atgctctgga ttatgcacaa gcgggtatct gctttttgcc atcacttctt aactggggac
     4921 acccctccct tcaatgccta aagaaatact aaccaaccaa aagagaaatg agaagccata
     4981 tttttatata gtattgagac acaaaagtta tagacactga atgctttttc atagtgagta
     5041 tgttttaagg aaatattaaa tttgatacat tatgaagtat atttttagac actgtttaga
     5101 aaggactcag tgaagaatca aatcagagaa aggtggtgcc taagagtact taagaaaatt
     5161 tccatctcat tctaggtcaa attcaatttt atataggcct cttataatat atatttataa
     5221 agcattactt ttatgtattt ttcaaaacta ccaactgaaa ttcaatcata aaacgtttta
     5281 aaatacaaat acacattcaa attatatatc atttcccccc atctgctctg ttatcaattt
     5341 tagcccaatt acaagcaagt ccttgtaaag taaatcctat cggggggagc aaaaaagcta
     5401 catctttgcg cttacattgt accaaaggct gaggaaatgt gtcttcagta atattatgtg
     5461 tattgtaatg gtattgtaat gtgtgtgtta ctacagtata cagtacttca gtaatttcaa
     5521 gtgttacaac tgcaaaacca cttttgacca gcaagtggca gtttgcttca gtattttcca
     5581 attttttttt tcttcaaatc agaagggtca gtgtattata tacaaagagg gttatatata
     5641 tatataacgt gatactcttc attttcatgt tggcaatgaa aattttcagt ggtgtttctt
     5701 aatattctat cttgtgccat ggtgaataaa atgttaagca aaaa
//
