LOCUS       XM_017602284            5613 bp    mRNA    linear   ROD 11-JUN-2023
DEFINITION  PREDICTED: Rattus norvegicus Rho GTPase activating protein 6
            (Arhgap6), transcript variant X1, mRNA.
ACCESSION   XM_017602284
VERSION     XM_017602284.2
DBLINK      BioProject: PRJNA677964
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_051356.1) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            [WARNING] On Feb 22, 2024 this sequence was replaced by
            XM_017602284.3.
            
            On Jan 21, 2021 this sequence version replaced XM_017602284.1.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_015227675.2-RS_2023_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.1
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/06/2023
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5613
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN/NHsdMcwi"
                     /db_xref="taxon:10116"
                     /chromosome="X"
                     /sex="male"
                     /tissue_type="kidney"
                     /geo_loc_name="USA: Wisconsin, Milwaukee, Medical College
                     of Wisconsin"
                     /collection_date="2019-03-08"
                     /collected_by="Rebecca Schilling"
     gene            1..5613
                     /gene="Arhgap6"
                     /note="Rho GTPase activating protein 6; Derived by
                     automated computational analysis using gene prediction
                     method: Gnomon. Supporting evidence includes similarity
                     to: 5 ESTs, 9 Proteins, and 100% coverage of the annotated
                     genomic feature by RNAseq alignments, including 17 samples
                     with support for all annotated introns"
                     /db_xref="GeneID:100363276"
                     /db_xref="RGD:2323364"
     CDS             1339..4296
                     /gene="Arhgap6"
                     /codon_start=1
                     /product="rho GTPase-activating protein 6 isoform X1"
                     /protein_id="XP_017457773.1"
                     /db_xref="GeneID:100363276"
                     /db_xref="RGD:2323364"
                     /translation="MSAQSLLHSVFSCSSPASGGTASTKGFSKRKLRQTRSLDPALIS
                     GCGSEMGAEDGLRGSTVSRLNSPQLSAESLGSRLASSPRSQHLRATRFPAPRPLCSSF
                     STPSTPQEKSPSGSFHFDYEVPLSRSGLKKSMAWDLPSVLTGSVSGRNPASILGSSGG
                     GPNGIFASPRRWLQQRKFQPPPNSRSHPYVVWRSEGDFTWNSMSGRSVRLRSVPIQSL
                     SELERARLQEVAFYQLQQDCDLGCQITIPKDGQKRKKSLRKKLDSLGKEKNKDKEFIP
                     QAFGMPLSQVIANDRAYKLKQDLQREEQKDASDFVSSLLPFGNKKQNKELSSSNSSLS
                     STSETPNESTSPNTPEPAPRARRRGAMSVDSITDLDDNQSRLLEALQLSLPAEAQNKK
                     QKARDKKLSLNPIYRQVPRLVDSCCQHLEKHGLQTVGIFRVGSSKKRVRQLREEFDRG
                     VDVCLEEEHSVHDVAALLKEFLRDMPDPLLTRELYTAFINTLLLEPEEQLGTLQLLIY
                     LLPPCNCDTLHRLLQFLSIVARHAEDNVSKDGQEVTGNKMTSLNLATIFGPNLLHKQK
                     SSDKEYSVQSSARAEESTAIIAVVQKMIENYEALFMVPPDLQNEVLISLLETDPDVVD
                     YLLRRKASQSSSPDMLQSEVSFSMGGRHSSTDSNKASSGDISPYDNNSPVLSERSLLA
                     MQEDRARGGSEKLYKVPEHYTLLDHLPSPKSKSRESSPGPRLGKDMSEEPFNIWGTWH
                     STLKSGSKDPGMTGSYGDIFESSSLRPRLCSLSQGNLSLNWPRCQGSTTGMDSGTQVI
                     RRTQTAATVEQCNVHLPVSRVCSTPHIQDGGRGSRRPAARSEPFLSLNSTEDLAEGKE
                     DVAWLQSQAQAVYQRPQESGRDDRRPPPPYPGSGKPATTSAQQPLEPPLWRLQRQEEG
                     SETVVEEGGQQASGEHQTRPKKLSSAYSLSASEQDKQNLGEASWLDWQRERWQIWELL
                     STDNPDALPETLV"
ORIGIN      
        1 gagaagaggg gaggagagga gaggagagga gaggagagga gagaaggcag gggatttaac
       61 tctacgttca gaaaaaccct cctgggctga gggtctgaca ccagtgggtg gggtgcaatc
      121 tgacactccc cttcctttgc agaaacttgt gtggagacag caaaggcaag cccctagctt
      181 ggggggaggg gagtcggggg agaaggtccg cacttccgtc ctcaagactt tctccctaga
      241 ggccgggtat cagagacatg ctgccggctc tctgagctac ttcccaggtt tggcgcctgg
      301 aaaagttcac gttctacatt ctcccgctcc tggctccgcc ccggctccag accctgcgtt
      361 cttctggcct tacccgggac gggccacccc tttccccgct ccctctggcg cgagggtgct
      421 gggacatctc tcagccagct ctgggcccaa tcaaggttgg cagcaaatat caagtgtctc
      481 tctccagagg aacacggata cccgcttcgg aggggaggct gttttctgag ctcagacctt
      541 actgagtagc tctgagcgca gcaggggagt tccttgccac agttgtcgct cggtgctcgg
      601 aaggcccggg acgcagcaaa cacggtgccc cactaagggc accaggaccg ctcgggaacg
      661 tgaacttaga gacacttttg agcctcgtga gtcagaaagg gggatgtcgc agcccagctg
      721 atcccccaaa gcacagccga ggtccccaag tcaccaagaa ggtgcaccgg gggcgcagcc
      781 gggcaactga actcgggagc tccagaagag ttctcaccgc gtccggagcg ccaaggaccc
      841 gctcaaggcg gactctcagg cagcctcctc cctagccctc gggattgtcc tcaggccacg
      901 aggaggagct tgctggagac ttcgaggctg tccagagcca gagagctgga gcgcagcgtc
      961 tcccgccttc agctgggaag ggggagtggc gctgacgggt tggagctgag atctcagcta
     1021 gtcactgacc tctttcctcc tctcccttag cctctttgag acttggacta cctggggaag
     1081 gttcagagac cgtataggga tcgggacctc ttgtttccta gaaggctggg gatggagttc
     1141 ctgtttctgc ctccgcagga acacttggag agcgctggtg gcgcgtgaac gggacactac
     1201 cttccacctt cctcggtgat ccctgcctgg cagtttttcc ctttcctact ccagccactt
     1261 gttttctcag gtcacagtct ccagcgatcc aggagggaaa acgagaagaa ggtggccctc
     1321 aaacccaacc ctgccgagat gtccgcgcag agcctgctgc acagtgtctt ctcctgctcc
     1381 tcgcccgcgt cgggcggcac ggcctcgacc aagggattct ccaaaaggaa gctgcgccag
     1441 acgcgcagtc tggacccagc cctgatcagt ggctgcggga gtgagatggg cgccgaggat
     1501 ggcctgcggg gctccacagt aagccgactc aattctccgc agctctctgc agagagtctc
     1561 ggttcccgct tagcttcttc tccccggagt cagcaccttc gggctaccag gttcccggca
     1621 cccagacctc tatgttcgtc tttctccaca cctagtaccc cgcaagaaaa gtcgccttct
     1681 ggcagcttcc actttgacta cgaagtccca ctgagtcgca gtggtcttaa gaagagcatg
     1741 gcctgggacc tgccttctgt cctgaccggg tccgtgagtg gccgcaatcc tgcaagcatc
     1801 ctgggttcct ccgggggagg ccccaatggc atcttcgctt ctcctaggag atggctccag
     1861 cagaggaagt tccaacctcc accgaacagt cgcagccacc cttacgtcgt gtggaggtct
     1921 gagggtgact tcacctggaa cagcatgtct ggccgtagtg tgcgcctgag atctgtccct
     1981 atccaaagcc tctcagagct ggagcgggca cggctgcagg aagtggcttt ttatcagttg
     2041 cagcaggact gtgacctggg ctgtcagatc accattccca aagatggaca aaagagaaag
     2101 aaatctttga gaaagaaact ggattcgcta gggaaggaaa agaacaaaga caaagaattc
     2161 atcccacagg catttggaat gcccttatcc caagtcattg ctaatgaccg ggcatataaa
     2221 ctgaagcaag atttgcagag ggaggagcag aaggatgcat cggattttgt gtcttcgctc
     2281 ctcccatttg ggaataaaaa acaaaacaaa gaactctcaa gcagtaactc atctctcagc
     2341 tcaacctcag aaacaccaaa tgagtctaca tccccaaaca ctccagaacc agctccccgg
     2401 gccaggagaa ggggtgccat gtccgtggat tccatcacag atctggatga caaccagtct
     2461 cgactcctag aagctttaca actctccttg cctgctgagg ctcagaataa aaaacaaaag
     2521 gccagagata agaagctgag tctgaatcct atttacaggc aggttcccag gctagtggac
     2581 agctgctgtc agcatctgga aaaacatggc ctccagaccg tggggatatt ccgagttgga
     2641 agctcaaaaa agcgagtaag acaattgcgt gaggaatttg accgtggggt tgatgtctgt
     2701 ctggaagagg agcacagtgt tcatgatgtg gcagccttgt taaaggagtt cctcagagac
     2761 atgcctgacc cccttctcac aagggagcta tacactgcat ttatcaacac tctcttgttg
     2821 gagcctgagg aacaactggg caccttgcaa ctcctcatct accttctacc tccctgcaac
     2881 tgcgacaccc tccaccgcct cctacagttc ctctccattg ttgccaggca tgctgaagat
     2941 aatgtcagca aagatggaca agaggtcact gggaacaaaa tgacatctct gaacttggct
     3001 accatatttg gacccaacct gctccacaag cagaagtcat cagacaaaga atattctgtc
     3061 cagagctcag ccagagctga agagagcaca gccatcatag ctgtggtaca gaagatgatt
     3121 gaaaattatg aagccctctt catggttccc ccagatctcc agaatgaagt gctgatcagc
     3181 cttctggaga cagatccgga tgttgtggac tacctgctca gaagaaaggc ttcccaatcc
     3241 tcgagccctg acatgcttca gtcggaagtt tccttttcca tgggagggag gcattcatct
     3301 acagactcca acaaggcctc cagtggagac atctcccctt atgacaacaa ctccccagta
     3361 ctgtctgagc gctccctgct ggctatgcaa gaagacaggg cccggggggg ctcggagaag
     3421 ctttataaag tgccagagca ttatacactg ttggaccact tgccatcgcc aaagtcgaag
     3481 tcaagagaaa gttctcctgg accaaggctt ggaaaagata tgtcagagga gcctttcaat
     3541 atctggggaa cttggcattc aacattaaaa agcggatcca aagacccagg aatgacaggt
     3601 tcctatggtg acatttttga aagcagctcc ctccgaccga ggctgtgttc cctctctcaa
     3661 gggaacctat ccctgaattg gcctcggtgt caagggagca ccacaggaat ggacagtggc
     3721 actcaggtaa ttcggaggac tcagacagcg gccaccgtgg agcagtgcaa tgtccacctt
     3781 ccggtgtcac gtgtctgcag cactccccac atccaggacg gcggcagggg gtccaggcgg
     3841 cctgcagcca ggtctgagcc atttttgtcc ttaaacagca cggaagacct ggccgagggc
     3901 aaggaggatg tggcctggct gcaaagccag gcccaagccg tgtaccagag acctcaggag
     3961 agtggtagag atgacaggcg cccccctcca ccttacccag ggtcagggaa gcctgccacg
     4021 acctcggccc agcagccact agagcctccc ctgtggaggc tccagaggca ggaagaaggt
     4081 tcagaaacag ttgtggaaga aggaggccag caggcctcag gggaacatca gaccaggcca
     4141 aaaaaactga gcagcgccta ctccctctca gccagtgagc aggacaagca gaacttaggg
     4201 gaagccagct ggctcgactg gcagcgagag cggtggcaga tctgggagct cttgtcgact
     4261 gacaaccccg atgccctccc ggaaacccta gtataagccc gccagcagct ggagcccacc
     4321 cttccaaaaa acatcttccg gcccagaccc ggaaactatg gacaattgga cacttactcg
     4381 tttttctttt tgtttttcca cattttgaaa aagtaacaca agagaaagtc cacttccaga
     4441 ttcacttcta cccttgccat ttatggtaag actctattgc atagccagcc ttagaaaaag
     4501 caaacaaaca tgacaattcc caatctaaaa acccacattg gctttatgta aaatcaaact
     4561 cttgctttgt tatagcttaa gtgtatttat gtgtcttcaa ttttggctat tgtgtattct
     4621 gtaacaaatt atgtatatca atatgatatt cacagagaag acagaacaat tagaaaaaat
     4681 cactgcactt atattacact ttgagatata ttaagcaacc agattctata tgctctggat
     4741 tatgcacaag cgggtatctg ctttttgcca tcacttctta actggggaca cccctccctt
     4801 caatgcctaa agaaatacta accaaccaaa agagaaatga gaagccatat ttttatatag
     4861 tattgagaca caaaagttat agacactgaa tgctttttca tagtgagtat gttttaagga
     4921 aatattaaat ttgatacatt atgaagtata tttttagaca ctgtttagaa aggactcagt
     4981 gaagaatcaa atcagagaaa ggtggtgcct aagagtactt aagaaaattt ccatctcatt
     5041 ctaggtcaaa ttcaatttta tataggcctc ttataatata tatttataaa gcattacttt
     5101 tatgtatttt tcaaaactac caactgaaat tcaatcataa aacgttttaa aatacaaata
     5161 cacattcaaa ttatatatca tttcccccca tctgctctgt tatcaatttt agcccaatta
     5221 caagcaagtc cttgtaaagt aaatcctatc ggggggagca aaaaagctac atctttgcgc
     5281 ttacattgta ccaaaggctg aggaaatgtg tcttcagtaa tattatgtgt attgtaatgg
     5341 tattgtaatg tgtgtgttac tacagtatac agtacttcag taatttcaag tgttacaact
     5401 gcaaaaccac ttttgaccag caagtggcag tttgcttcag tattttccaa tttttttttt
     5461 cttcaaatca gaagggtcag tgtattatat acaaagaggg ttatatatat atataacgtg
     5521 atactcttca ttttcatgtt ggcaatgaaa attttcagtg gtgtttctta atattctatc
     5581 ttgtgccatg gtgaataaaa tgttaagcaa aaa
//
