LOCUS       NM_001108067            3891 bp    mRNA    linear   ROD 26-FEB-2024
DEFINITION  Rattus norvegicus Rho GTPase activating protein 45 (Arhgap45),
            mRNA.
ACCESSION   NM_001108067 XM_001073188 XM_234898
VERSION     NM_001108067.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 3891)
  AUTHORS   Ghosh D, Lippert D, Krokhin O, Cortens JP and Wilkins JA.
  TITLE     Defining the membrane proteome of NK cells
  JOURNAL   J Mass Spectrom 45 (1), 1-25 (2010)
   PUBMED   19946888
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH474029.1.
            
            On or before Oct 4, 2007 this sequence version replaced
            XM_234898.4, XM_001073188.1.
            
            ##Evidence-Data-START##
            RNAseq introns :: mixed sample support SAMD00132263, SAMD00132266
                              [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..3891
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="7"
                     /map="7q11"
     gene            1..3891
                     /gene="Arhgap45"
                     /gene_synonym="Hmha1; RGD1308662"
                     /note="Rho GTPase activating protein 45"
                     /db_xref="GeneID:314618"
                     /db_xref="RGD:1308662"
     exon            1..198
                     /gene="Arhgap45"
                     /gene_synonym="Hmha1; RGD1308662"
                     /inference="alignment:Splign:2.1.0"
     CDS             106..3456
                     /gene="Arhgap45"
                     /gene_synonym="Hmha1; RGD1308662"
                     /note="minor histocompatibility protein HA-1;
                     histocompatibility (minor) HA-1"
                     /codon_start=1
                     /product="rho GTPase-activating protein 45"
                     /protein_id="NP_001101537.1"
                     /db_xref="GeneID:314618"
                     /db_xref="RGD:1308662"
                     /translation="MFSRKKRELMKTPSISKKNRAGSPNPQSSSGELPRKDCTETPSL
                     EPPAMSLSTVAKGTGTLKRPTSLSRHASAAGFPLSGTATRTLGRGYRSPLSAASPAEL
                     PTEGPFPDGVEDISTLLADVARFAEGLEKLKEFVLRDDLLEARRPLAHECLGEALRVM
                     RQVISKYPLLNTVETLTAAGTLIAKVKAFHYECNNESDKREFEKALETIAVSFSCTVS
                     EFLLGEVDSSTLLAVPPGDPSQLVENLYGSGSEGPPHSVEDCEEGCLPPEEVDMLLQR
                     CEGGVDAALQYAKDMARYMKDLIGYLEKRTTLEMEFAKGLQKVVHNCRQNVTHAPHMP
                     LLSIYSLALEQDLEFGHGMVQAVGTLQTQTFMQPLTLRRLEHERRRKEIKESWHRAQR
                     KLQEAEANLRKAKQGYKQRCEDHDKARLQVAKAEEEQQGTGPGAGTAASKALDKRRRL
                     EEEAKNKAEEAMATYRTCVADAKTQKQELEDTKVTALRQIQEVIRQSDQTIKSATISY
                     YQLMHMQTAPLPVNFQMLCESSKLYDPGQQYASHVRQLQRGEEPDVRYDFEPYVSTNA
                     WSPIMRTRKGSFNPGDASGPEAAGSPPEEGGTSEGAPNKDHRGGRGHQVHKSWPISIS
                     DTEVSLDVSSGDLKKFDRTSSSGTMSSNEELVDQEAGLVASAFDSADLNGMDPELPVA
                     MPSGPFRHVGLSKAARTHRLRKLRTPAKCRECNSYVYFQGAECEECCLACHKKCLETL
                     AIQCGHKKLQGRLQLFGQDFSQAAHSTPDGVPFIIKKCVCEIERRALHTKGIYRVNGV
                     KTRVEKLCQAFENGKELVELSQASPHDISNVLKLYLRQLPEPLISFRFYHELVGLAKD
                     SLKAEAEAKAASRGRQDGSESEAATLAMVGRLRELMRDLPAENRATLLYLLRHLRRIV
                     EMEQDNKMTPGNLGIVFGPTLLRPRPTDATVSLSSLVDYPHQARVIETLIVHYGLVFE
                     EEPEEAAGSQEGASAQCAQLETAEGIVFPQQEEADDGNRESQVASNDSDSELEEASDL
                     LSSSDASALHRLSFLEQTEAGLEEGPQSHSGSEEQLESEDAAPGHQLCSFNTNQSNNT
                     TQASLPTMRLRDGQITGGSGRKRQPQFV"
     exon            199..523
                     /gene="Arhgap45"
                     /gene_synonym="Hmha1; RGD1308662"
                     /inference="alignment:Splign:2.1.0"
     exon            524..667
                     /gene="Arhgap45"
                     /gene_synonym="Hmha1; RGD1308662"
                     /inference="alignment:Splign:2.1.0"
     exon            668..752
                     /gene="Arhgap45"
                     /gene_synonym="Hmha1; RGD1308662"
                     /inference="alignment:Splign:2.1.0"
     exon            753..825
                     /gene="Arhgap45"
                     /gene_synonym="Hmha1; RGD1308662"
                     /inference="alignment:Splign:2.1.0"
     exon            826..892
                     /gene="Arhgap45"
                     /gene_synonym="Hmha1; RGD1308662"
                     /inference="alignment:Splign:2.1.0"
     exon            893..1030
                     /gene="Arhgap45"
                     /gene_synonym="Hmha1; RGD1308662"
                     /inference="alignment:Splign:2.1.0"
     exon            1031..1095
                     /gene="Arhgap45"
                     /gene_synonym="Hmha1; RGD1308662"
                     /inference="alignment:Splign:2.1.0"
     exon            1096..1206
                     /gene="Arhgap45"
                     /gene_synonym="Hmha1; RGD1308662"
                     /inference="alignment:Splign:2.1.0"
     exon            1207..1287
                     /gene="Arhgap45"
                     /gene_synonym="Hmha1; RGD1308662"
                     /inference="alignment:Splign:2.1.0"
     exon            1288..1476
                     /gene="Arhgap45"
                     /gene_synonym="Hmha1; RGD1308662"
                     /inference="alignment:Splign:2.1.0"
     exon            1477..1614
                     /gene="Arhgap45"
                     /gene_synonym="Hmha1; RGD1308662"
                     /inference="alignment:Splign:2.1.0"
     exon            1615..1805
                     /gene="Arhgap45"
                     /gene_synonym="Hmha1; RGD1308662"
                     /inference="alignment:Splign:2.1.0"
     exon            1806..1930
                     /gene="Arhgap45"
                     /gene_synonym="Hmha1; RGD1308662"
                     /inference="alignment:Splign:2.1.0"
     exon            1931..2008
                     /gene="Arhgap45"
                     /gene_synonym="Hmha1; RGD1308662"
                     /inference="alignment:Splign:2.1.0"
     exon            2009..2113
                     /gene="Arhgap45"
                     /gene_synonym="Hmha1; RGD1308662"
                     /inference="alignment:Splign:2.1.0"
     exon            2114..2286
                     /gene="Arhgap45"
                     /gene_synonym="Hmha1; RGD1308662"
                     /inference="alignment:Splign:2.1.0"
     exon            2287..2475
                     /gene="Arhgap45"
                     /gene_synonym="Hmha1; RGD1308662"
                     /inference="alignment:Splign:2.1.0"
     exon            2476..2613
                     /gene="Arhgap45"
                     /gene_synonym="Hmha1; RGD1308662"
                     /inference="alignment:Splign:2.1.0"
     exon            2614..2840
                     /gene="Arhgap45"
                     /gene_synonym="Hmha1; RGD1308662"
                     /inference="alignment:Splign:2.1.0"
     exon            2841..3051
                     /gene="Arhgap45"
                     /gene_synonym="Hmha1; RGD1308662"
                     /inference="alignment:Splign:2.1.0"
     exon            3052..3139
                     /gene="Arhgap45"
                     /gene_synonym="Hmha1; RGD1308662"
                     /inference="alignment:Splign:2.1.0"
     exon            3140..3891
                     /gene="Arhgap45"
                     /gene_synonym="Hmha1; RGD1308662"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gaaacaacca gcaccaggcg ctgcaggact gagaccaccc cccagtcccc cacccctgcc
       61 gctgcctgtc tgtcctcacc tagagccact ggggctggct ccaccatgtt ctctcggaag
      121 aagcgagaac ttatgaaaac tccctctatt tccaaaaaga accgcgcggg gagccccaac
      181 ccgcagtcct cctcagggga gctgcctcgg aaagactgta cagaaactcc tagcctggag
      241 ccaccagcca tgtccctgtc cacggtggcc aagggcacag gaacactcaa aaggccaacc
      301 agcctgagcc gccatgccag cgctgcaggc ttcccactct cgggcactgc cacacggact
      361 ctgggccgtg gatatcgaag ccccctctct gctgccagcc ccgcagagct acccactgag
      421 ggacctttcc ctgacggtgt agaagacatc tcaaccctgc tggctgatgt tgcccgcttt
      481 gctgagggct tggagaagct caaggagttt gtgctgcggg atgatctcct tgaggcccgc
      541 cggcccctgg ctcatgaatg cctgggtgaa gctctgcgag tcatgcgtca ggtcatctcc
      601 aaatacccac tcctgaacac cgtggagaca ctcacagctg ctggtacact cattgccaag
      661 gtcaaagcct ttcattatga atgcaacaat gaatcagata agagggagtt tgagaaggca
      721 ctggagacca ttgctgtgtc cttcagctgc actgtgtcgg agttcctttt gggtgaagtg
      781 gacagcagta cactcctggc tgtgcctccg ggggacccta gccagttggt ggagaacctt
      841 tatgggtcag gcagtgaggg gcccccacac agcgtggagg attgtgaaga aggttgcctg
      901 ccccccgagg aggtggacat gcttctccag cgctgcgagg gaggtgtgga cgccgcgctg
      961 cagtatgcaa aagacatggc caggtacatg aaggacctca tcggctacct ggagaagagg
     1021 accaccctgg agatggaatt cgccaaaggg ctgcagaagg tcgtccataa ctgcagacag
     1081 aacgtcactc atgcgcccca catgcctctc ttatccatct actcactggc cctggaacaa
     1141 gatctggagt ttggccacgg catggtgcag gcagtgggca cgctgcagac ccagaccttc
     1201 atgcagcccc tgaccctgcg gcggttggag catgagagac gcaggaagga gatcaaagaa
     1261 tcctggcatc gtgcacagag gaagctgcaa gaggcagagg ccaacctgcg caaggctaaa
     1321 cagggctaca aacaacgttg tgaagaccac gacaaggccc ggctccaggt ggccaaggct
     1381 gaggaggaac aacagggcac agggccagga gcagggactg cagcctccaa ggccctggac
     1441 aagaggcgga ggctggagga agaggccaaa aacaaggccg aggaggccat ggccacttac
     1501 cgcacatgcg tggcagatgc aaagacacag aagcaagagc tggaggacac aaaggtgact
     1561 gcgctgcgac agatccagga ggtcatcaga cagagtgatc agaccattaa gtcggccacc
     1621 atctcctact accagctgat gcacatgcag acagcgccgc tgcctgtgaa cttccagatg
     1681 ctgtgcgaga gcagcaaact atatgacccg ggccaacagt acgcatctca cgtgcgtcag
     1741 ctgcagcgag gcgaggagcc ggatgtgcgc tacgactttg agccttatgt ctccaccaat
     1801 gcctggtccc caatcatgcg aacacggaag ggcagcttca atcctggtga cgcttcagga
     1861 cccgaagctg ccggcagtcc cccggaggaa ggtggcacgt ctgagggggc tcccaacaag
     1921 gaccacaggg ggggacgagg tcatcaggta cataagtcct ggcctatctc catctcagac
     1981 accgaagtca gcctggacgt cagctcaggg gacttgaaga agttcgatcg aacctcgtcc
     2041 agcgggacca tgtcatccaa tgaggagctg gtagatcagg aagctggctt ggtcgcctcc
     2101 gcttttgatt cagctgacct caatggcatg gatcccgagt tacctgttgc catgcccagt
     2161 ggacccttcc gccatgtggg attgtccaag gcagcccgca cacaccgact tcgcaagctg
     2221 cgaacgccgg ccaagtgcag agagtgtaac agctacgtgt acttccaagg ggccgaatgt
     2281 gaagagtgct gtctggcttg tcacaaaaag tgtttggaga ccctggctat ccagtgtggt
     2341 cacaagaagc ttcagggccg cctgcagctg tttggtcaag acttcagcca ggcagcccac
     2401 agcacccctg atggggtgcc cttcattatt aaaaagtgtg tctgtgagat tgagcggcgg
     2461 gcactgcaca ctaaggggat ctaccgggtc aacggcgtga aaacgcgtgt ggagaagctg
     2521 tgccaggcct ttgagaatgg caaagagctg gtggagttgt cacaggcctc accgcacgac
     2581 ataagcaatg tcctgaagct gtacctacgg cagctgccgg agcccctcat ctcttttcgc
     2641 ttctaccatg agctggtggg attagctaag gacagcctaa aggcagaggc cgaagccaag
     2701 gcagcaagcc ggggccggca ggacgggtcc gagagtgagg ctgcgacctt ggccatggtg
     2761 ggccgcctgc gagagctcat gcgggacctg ccagccgaaa accgggccac actcttatac
     2821 ctgctgaggc acctgcgaag gatcgtggaa atggagcaag ataacaagat gacccccggg
     2881 aacctgggca tcgttttcgg gcccacactg ctgcggcctc ggcccacaga cgccaccgtg
     2941 tccctctctt ctctggtgga ctacccccac caggcccgtg tcattgagac tctgattgtc
     3001 cactatggcc tggtctttga ggaggagcca gaagaagcag ctggcagcca agagggggcg
     3061 tccgcccagt gtgcccagct ggagactgct gagggcattg tcttccccca gcaggaggag
     3121 gcggacgatg gaaaccgaga atcccaggtg gcatccaatg actcagactc agagctggaa
     3181 gaggcttctg acctcctttc gtcctcggac gccagcgccc tgcaccgcct cagtttcctg
     3241 gagcagaccg aggcaggcct ggaggaaggt ccccagagcc acagtggcag tgaggaacag
     3301 ctggagagtg aggatgcagc cccaggccat cagctgtgtt ccttcaacac caaccagtcc
     3361 aacaacacca cacaagcctc tctgcccacc atgcgactcc gagatgggca gatcacaggt
     3421 ggcagcggtc ggaagcggca gccacagttt gtctgagctg ggtggtgatg ttggggacca
     3481 tcagctcact gccagctact cttaagggtc actatgggcc cttgacttgt tttgggggtt
     3541 ttctcacaat gccgagaagc ttgagggagc tcagggcacc ctggcaccat ggactcagat
     3601 ggatagtggt cccaggtgga cttgcctggc cttcgtgtgc ctgtgcctgt gcctgatgca
     3661 gccgccgagt cccatgatgc cttcgtctct cccacggccc ccatcagtct ggatgtgtct
     3721 gagtgggcac agcaccagga caggatgctg tgtggtgtgc agtcctggct ctggcttcag
     3781 gaatcttgca ggagtctggg catggaaaga caggtggggg tacacagtgg gtctctccca
     3841 aggagcagtg aaagagcttt gcacgtgcac ccccaatttg cttgaataaa c
//
