LOCUS       XM_576354               5672 bp    mRNA    linear   ROD 11-JUN-2023
DEFINITION  PREDICTED: Rattus norvegicus Rho GTPase activating protein 42
            (Arhgap42), transcript variant X1, mRNA.
ACCESSION   XM_576354
VERSION     XM_576354.8
DBLINK      BioProject: PRJNA677964
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_051343.1) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            [WARNING] On Feb 22, 2024 this sequence was replaced by
            XM_576354.9.
            
            On Jan 21, 2021 this sequence version replaced XM_576354.7.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_015227675.2-RS_2023_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.1
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/06/2023
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5672
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN/NHsdMcwi"
                     /db_xref="taxon:10116"
                     /chromosome="8"
                     /sex="male"
                     /tissue_type="kidney"
                     /geo_loc_name="USA: Wisconsin, Milwaukee, Medical College
                     of Wisconsin"
                     /collection_date="2019-03-08"
                     /collected_by="Rebecca Schilling"
     gene            1..5672
                     /gene="Arhgap42"
                     /note="Rho GTPase activating protein 42; Derived by
                     automated computational analysis using gene prediction
                     method: Gnomon. Supporting evidence includes similarity
                     to: 23 ESTs, 20 Proteins, and 100% coverage of the
                     annotated genomic feature by RNAseq alignments, including
                     67 samples with support for all annotated introns"
                     /db_xref="GeneID:500943"
                     /db_xref="RGD:1564081"
     CDS             28..2655
                     /gene="Arhgap42"
                     /codon_start=1
                     /product="rho GTPase-activating protein 42 isoform X1"
                     /protein_id="XP_576354.3"
                     /db_xref="GeneID:500943"
                     /db_xref="RGD:1564081"
                     /translation="MGLPTLEFSDSYLDSPDFRERLQCHEIELERTNKFIKELLKDGS
                     LLIGALRNLSMAVQKFSQSLQDFQFECIGDAETDDEISIAQSLKEFARLLIAVEEERR
                     RLIQNANDVLIAPLEKFRKEQIGAAKDGKKKFDKESEKYYSILDKHLNLSAKKKESHL
                     QEADSQIGREHQNFYEASLEYVFKIQEVQEKKKFEFVEPLLSFLQGLFTFYHEGYELA
                     QEFAPYKQQLQFNLQNTRNNFESTRQEVERLMQRMKAANQDYRPPSQWTMEGYLYVQE
                     KRPLGFTWTKHYCTYDKGSKMFTMSVSDVKASGKMNGLVTGSPEMFKLKSCIRRKTDS
                     IDKRFCFDIEVVERHGIITLQAFSEANRKLWLEAMDGKEPIYTLPAIISKKEEMYLNE
                     AGFNFVRKCIQAVETRGINILGLYRIGGVNSKVQKLMNTTFSPKSPPDMDIDIELWDN
                     KTITSGLKNYLRCLAEPLMTYKLHKDFIIAVKSDDQNYRVEAVHALVHKLPEKNREML
                     DILIKHLLKVSLHSQQNLMTISNLGVIFGPTLMRAQEETVAAMMNIKFQNIVVEILIE
                     HYEKIFHTAPDPNIPLPQPQSRSGSRRTRAICLSTGSRKPRGRYTPCLAEPDSDSYSS
                     SPDSTPMGSIESLSSHSSEQNSTTKSTSCQPREKSGGIPWIAAPSSSNGQKSLGLWTT
                     SPESSSREDATKTDVESDCQSVASVTSPGDVSPPIDLVKKGPYGLSGLKRSSASSSLR
                     SISAAEGNKSYSGSIQSLTSIGSKESPKATPNPELPPKMCRRLRLDTASSNGYQRPGS
                     VVAAKAQLFENAGSLKPVSSGRQAKAMYSCKAEHSHELSFPQGAIFSNVHPSVEPGWL
                     KATYEGRTGLVPENYVVFL"
ORIGIN      
        1 gcagctagcg gccgccgcgc ctgggccatg gggctgccca ctctggagtt cagcgattct
       61 tatttggaca gtccggattt cagggagcga ttgcagtgtc acgagatcga gctggagaga
      121 accaacaagt tcatcaaaga gctgctgaag gatggctctc tgctcatcgg ggcgctgaga
      181 aatctgtcca tggctgtaca gaagttttcc cagtctctgc aagacttcca gtttgagtgt
      241 atcggagatg cagaaactga tgacgagatc agtattgctc aatcactgaa agaatttgca
      301 aggctactca ttgctgtaga agaagaaagg cgtagactga ttcaaaatgc taatgatgtg
      361 ttaatcgcac cccttgagaa atttcgaaaa gagcagatcg gtgcagctaa agatggaaag
      421 aagaagtttg acaaagagag tgaaaaatac tattctattc tggataaaca tttgaatttg
      481 tcggctaaga agaaggagtc tcatttgcaa gaggctgatt cacagattgg ccgagaacat
      541 cagaacttct atgaagcttc attagaatat gtctttaaaa tccaagaggt tcaagagaaa
      601 aagaagtttg agtttgtgga accgcttttg tccttccttc agggtctgtt tacattttac
      661 catgagggat atgaacttgc ccaggaattt gcaccgtaca agcaacagct acaattcaac
      721 ttacaaaata caaggaacaa ctttgaaagt actcgacaag aggtggagag attgatgcag
      781 aggatgaagg ctgccaacca ggactacaga ccacccagcc agtggaccat ggagggctat
      841 ctttacgtcc aggagaaaag accactgggt ttcacctgga ctaaacacta ctgtacttac
      901 gacaaaggaa gcaaaatgtt cacaatgagc gtctctgatg tgaaagccag tgggaagatg
      961 aatggccttg ttactggttc acccgaaatg tttaagttaa agtcatgtat ccgacggaag
     1021 acagattcca ttgacaaacg cttctgcttt gacatagaag tggtcgaaag acatggcatc
     1081 atcacactac aggcattctc agaagctaac cggaaactct ggctggaggc catggacggg
     1141 aaagaaccga tttacacgtt gcccgccata attagcaaga aagaagaaat gtacttaaat
     1201 gaagcagggt tcaacttcgt gagaaaatgt atccaagctg tggaaacgag aggcatcaac
     1261 atcttgggcc tgtaccgaat aggaggagtg aactccaagg tccagaaact catgaacacc
     1321 acattttctc cgaagtcccc tcctgatatg gacattgata ttgagctgtg ggacaataag
     1381 actataacga gcgggctgaa aaactacctc aggtgccttg cagaaccact gatgacttac
     1441 aaactgcaca aggatttcat cattgctgtc aagtcagacg accaaaacta cagggtggag
     1501 gctgtccatg cactggtgca caaattgccg gagaaaaaca gagagatgct ggacatcttg
     1561 attaaacacc tgctcaaagt atctctacat agccaacaaa atctcatgac tatctcgaat
     1621 cttggcgtca tatttggtcc aacgctgatg agagcacagg aggaaaccgt ggctgctatg
     1681 atgaacatca agtttcagaa catagtggtg gagatcctga tcgagcacta tgagaagatt
     1741 tttcatactg ccccagaccc aaacattcct cttcctcagc ctcagtctcg atctggatcc
     1801 cgaaggacgc gtgccatctg cctgtccaca ggttctagga agcccagagg gaggtacaca
     1861 ccgtgcctgg cagagcctga tagtgactcc tatagcagca gcccagacag cacacccatg
     1921 ggcagcatag agtcactctc ctcccactcc tctgaacaaa acagcaccac aaagtctact
     1981 tcctgccagc ccagggagaa gtcaggtggg attccctgga tcgcagcccc atcatcttcc
     2041 aatggacaga aaagtctggg tctctggaca actagtccag aatcaagttc tcgagaagat
     2101 gcaaccaaaa cagacgtgga gtcagattgc cagagtgtgg cctcggtcac cagcccgggg
     2161 gacgtctctc cccccataga cctagtcaag aaagggccct atgggctctc aggactgaaa
     2221 agatcctctg cttcctcctc tctcagatcc atctctgcag cagaaggaaa caagagctac
     2281 agtggatcca ttcaaagctt aacttctata ggctccaaag agtcacccaa agccacacca
     2341 aacccagagc tgcctccaaa aatgtgccgg aggttaaggc tagacaccgc ctccagcaat
     2401 ggctaccagc gacctggctc agtagtggca gcaaaggctc aattatttga aaatgctggg
     2461 tcgctcaagc cagtttcttc tggacgccaa gccaaagcca tgtactcctg caaagcagag
     2521 cacagccatg agctgtcctt tccccagggg gcgatctttt ccaatgtaca tccatcagtg
     2581 gagccggggt ggctaaaggc gacttatgaa ggcagaacag gactagtccc tgaaaactac
     2641 gttgtcttcc tctaatagta ttagtggatg gcagtatctt catggtatcc atggtaacac
     2701 ataatcagtg ctataatttt atctgacaca gatatggggg accagccact aaaagaaaca
     2761 tctatgtgtc tcaagttttt caccagcaga ctatgtagct cctacttgat ggaaagagaa
     2821 acacacatat ttgcatcata gctattcttt ttgctgtttt cttactttta agatatgctt
     2881 ctctctctcc ctgtctctct ctctccctct ctcccactct ccctctctcc ctctcccttt
     2941 ctcagaggaa gtgatttgtg acagagtctg cttgctagca gttgcagaat cctagatacc
     3001 aaacccaatc ctgcataccc caaatttgga agtcagaaat ctgctctgcc catgttaaaa
     3061 tctgttcctt attgcctgat agtctctggg gaaccttgaa atcattactt taaaattgta
     3121 atttaaattg ttcatttatt atttttgttt ttttaatata ctgtttttat atgtgattgt
     3181 tttgctggtc ctaaacattt caagaaaatc agtccttatt ttatcataac tatattttat
     3241 ttgttttcta agatgatagt atttgaaagc aataatgtat atgaagtctg taaagtaagc
     3301 cgagtgtaag tcaaacactg attccaccat aagcagtcca tccagaacag tagatggttt
     3361 ctctgattcc aagcgcaagt cggagaaaca cgtctgtaaa gcctgtaagg gtatattttt
     3421 gtcgcaggct agatgtgact tatgaagccc agatgaacca tccttccttt agacgtcatg
     3481 taaactgatc ttgggacttt tataaaattt tccattaaaa cacacgtgtt aataaatcac
     3541 atgtgcacat cttttgcttc ctgtcagtat ggtgacattg taatggccat tgtgggccaa
     3601 tgtaaaggtg tggtgtacca tgcagccagc ccactggaac tgctacggcc tctggtttta
     3661 atgatgggga agttttggac tcagatgctg ttgtacaaat gataaagaca ttgtttgaac
     3721 tcttaattga gaaactgtgc cttctaaacc tttttttact ggaaacagga aatgaacacc
     3781 tactcgattc ttagaccaca aagtgtgctt tcttaaaaaa agatttattt atttatatga
     3841 atgttttgtc cacatgtgtg tatgtgtact acatgtatgc cttttaccca tgaaggtcag
     3901 aaaagagagg ctaatagcct tgaactagaa ttaccgaggg aactgagtta ctaatggtcg
     3961 taactccagc ccccgaccac agagtttgag agcaagccat cattgttaac aggagtggaa
     4021 tttacaaggt tttctaggat ggcattcagc catagccttt cctatgaatt ccactgaatt
     4081 atagacctca tacagcagag aggtatttac tcttccttat gaggttgcaa actaagggtt
     4141 gtatatcagc cactccttct atcataacct atttcaataa ttccaatgaa tatatacaat
     4201 gacaaaaagc acttcttctc cacagtctga aaggttgtct gcccagagca tgtgcccatg
     4261 tggccttgct atctaactga cttcttcaac cttttctcta cttcatagac acgcaggtgt
     4321 ctaaagagct acgaagctat tgttgtgtgg tataggctat agtcttggtt tattctgcat
     4381 tacatcagca cttctagaga aaataagcag agtattcaca cagcgctatg cctcagtgca
     4441 tttatgcttt taaataagtt aagatatgga ttagaattaa cgagtagaga gtaacacttg
     4501 acaaacagat gtatccaaaa ataacaccag tgaactgaag gccatgagtg caaagcatct
     4561 cacaaagatt tgacctgaga ggaaatcgat gaaatcttgg ctctttctct ttctttcctc
     4621 tggattctag tctctgtaca ctgcagtgag gtattgttaa accctttggt caaggtgggt
     4681 atctggtggt ttttagtata caaatggcat tgctgcctct ggtcaccgtt ttctgggact
     4741 gaaagtagcc tttgtaatgc accagttgcc tctctgcagg gctttctgtt gaagcccttt
     4801 gtcatcaacc ccttgcaacc tgttagatca gcacccctgc agggaagctg gtttgctctc
     4861 caagaccaac ttggcagtaa gtatccaata tctttctcca ctgctgctgc acagagaaat
     4921 cccaactttt cattttattt taatgtagac cctaacattc ctgcctccca attgtgagct
     4981 aaacccatgg atgctcactt agagctttgt aggactaggt tatgaaacac agctttcctt
     5041 tctgctggtg agatctactc tgtcagtatg tgtttgaggc tccttccctg aaacaagaca
     5101 caaacatgct ggttcatgtt gcacttgcgc tttaagagtt ctttctttgt gttgattgca
     5161 tatgtgagga aaccatgagg atatatggga gaaaggttaa gggcgctttc ccctgaagta
     5221 agtatcctgc agatgaggca tgcaagagca ctgcagagat gaagatgtgt gctctggagt
     5281 gcccggaagg aagctgtgca gggcaggaga gcatcgctgg tgatggaaag agtcccgctc
     5341 caaactgtga tgctatcaac ttcatgaaga acctgacctg ctcagggaca gtgagatgtg
     5401 ttagaactgt catacccaca ctctgaatgc tacagtatgc acccaaataa aggcctatag
     5461 tttgatggat gtgaggaaag cattggggac tgatgtaatt ctcttgggtg ttctgtatga
     5521 gtatccttgg gtttgaaaca ctggtatatt cgactcttgg cctgtgctgc cattctactc
     5581 catttggttc atacaagtta gtcattcaac tgaacgattt tcctaatgta ttgtttgcca
     5641 gtttctgaaa agtaaaagaa tctttcaatc tc
//
