LOCUS       NM_173122               4612 bp    mRNA    linear   ROD 31-MAR-2024
DEFINITION  Rattus norvegicus Rho GTPase activating protein 39 (Arhgap39),
            mRNA.
ACCESSION   NM_173122 XM_001073789 XM_576303
VERSION     NM_173122.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 4612)
  AUTHORS   Lim,J., Ritt,D.A., Zhou,M. and Morrison,D.K.
  TITLE     The CNK2 scaffold interacts with vilse and modulates Rac cycling
            during spine morphogenesis in hippocampal neurons
  JOURNAL   Curr Biol 24 (7), 786-792 (2014)
   PUBMED   24656827
REFERENCE   2  (bases 1 to 4612)
  AUTHORS   Nowak,F.V.
  TITLE     Cloning of two hypothalamic cDNAs encoding tissue-specific
            transcripts in the preoptic area and testis
  JOURNAL   Mol Endocrinol 4 (8), 1205-1210 (1990)
   PUBMED   2293025
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from
            JAXUCZ010000007.1.
            
            On Nov 26, 2008 this sequence version replaced NM_173122.2.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643295.29156.1,
                                           SRR26643299.32055.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA5760383,
                                           SAMEA5760386 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-150               JAXUCZ010000007.1  110419311-110419460 c
            151-317             JAXUCZ010000007.1  110368000-110368166 c
            318-737             JAXUCZ010000007.1  110355191-110355610 c
            738-821             JAXUCZ010000007.1  110346899-110346982 c
            822-2175            JAXUCZ010000007.1  110339901-110341254 c
            2176-2737           JAXUCZ010000007.1  110338496-110339057 c
            2738-2830           JAXUCZ010000007.1  110333596-110333688 c
            2831-2904           JAXUCZ010000007.1  110330615-110330688 c
            2905-3104           JAXUCZ010000007.1  110329819-110330018 c
            3105-3196           JAXUCZ010000007.1  110329053-110329144 c
            3197-3366           JAXUCZ010000007.1  110328313-110328482 c
            3367-4612           JAXUCZ010000007.1  110326918-110328163 c
FEATURES             Location/Qualifiers
     source          1..4612
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="7"
                     /map="7q34"
     gene            1..4612
                     /gene="Arhgap39"
                     /gene_synonym="Porf-2"
                     /note="Rho GTPase activating protein 39"
                     /db_xref="GeneID:500901"
                     /db_xref="RGD:1593158"
     exon            1..150
                     /gene="Arhgap39"
                     /gene_synonym="Porf-2"
                     /inference="alignment:Splign:2.1.0"
     exon            151..317
                     /gene="Arhgap39"
                     /gene_synonym="Porf-2"
                     /inference="alignment:Splign:2.1.0"
     CDS             232..3561
                     /gene="Arhgap39"
                     /gene_synonym="Porf-2"
                     /note="preoptic regulatory factor 2"
                     /codon_start=1
                     /product="rho GTPase-activating protein 39"
                     /protein_id="NP_775145.2"
                     /db_xref="GeneID:500901"
                     /db_xref="RGD:1593158"
                     /translation="MAMSQTQDYECRSHHVDEQEPRIPGSSTRLEWVEIIEPRTRERM
                     YANLVTGECVWDPPAGVRIKRTSEDQWWELFDPNTSRFYYYSAASQRTVWHRPQNCDI
                     IPLAKLQTLKQNTESPRASADSSPGRGSRDGSTGSSLEPEPEERAQELPVRGGRATTL
                     VTSKEETSSCSPPGVLLEKDYEVYRDYSADGQLLHYRTSSLRWNSGNKERMLIKVADR
                     EPSFLTPQGNGYPADNQPVGHHRRPSGSQHSPNLQTFVPDNDGTVFFPERRPSPFLRR
                     AELSGNCSPLLIQPRKPSSDSQPSSPRYGYEPPLYEEPPVEYQAPIYDEPPMDVQFEP
                     NSPYQTGSPQRSPGRKPHPFLQATKQTPTSPCQQLMRTKQKCPERFLSLEYSPVGKEY
                     VRQLVYVEQAGSSPKLRAGPRHKYAPNPGGGTYSLQPSPCLLRDQRLGVRSGDYSTME
                     GPESRSSQPPTPLPQAQEDAMSWSSQQDTMSSTGYSPGTRKRKNRKPSLCQVPSTSST
                     DGAGDLLGDQPLTEERSPCRSSLTPVKAETDLVRGTPEPFLAQARLAWEAQQAHFHMK
                     QRGSWDSQQDGSGYESDGAVPLPMPGPVVRAFSEDEALAQQDSKHWKRSTFEKLGFPQ
                     ILLEKSISVQTNLASPEPYLHPSQSEDLGACAQFENSRQNRSAVPSSSCVFPTFTLRK
                     PSSETDIENWASKHFNKHTQGLFRRKVSIANMLAWSSESIKKPMIVTSDRHVKKEACE
                     IFKLIQMYMGDRRAKADPLHVALEIATKGWSAQGLRDELYIQLCRQTTENFRLESLAR
                     GWELMAICLAFFPPTPKFHSYLEGYIYRHMDPVNDTKVTQHIKELLERNSKKKSKLRK
                     KPKPYVEEPDGVAISTYAKYCYHKLQKAALTGAKKGLKKPNVEEIRHAKNAVFSPSMF
                     GSALQEVMSMQKERYPDRQLPWVQTRLSEEVLALNGDQTEGIFRVPGDIDEVNALKLQ
                     VDQWKVPTGLEDPHVPASLLKLWYRELEEPLIPHEFYEQCIAHYESPEAAVAVVHALP
                     RINRMVLCYLIRFLQVFVQPANVAITKMDVSNLAMVMAPNCLRCQSDDPRVIFENTRK
                     EMSFLRVLIQHLDTSFMEGVL"
     exon            318..737
                     /gene="Arhgap39"
                     /gene_synonym="Porf-2"
                     /inference="alignment:Splign:2.1.0"
     exon            738..821
                     /gene="Arhgap39"
                     /gene_synonym="Porf-2"
                     /inference="alignment:Splign:2.1.0"
     exon            822..2175
                     /gene="Arhgap39"
                     /gene_synonym="Porf-2"
                     /inference="alignment:Splign:2.1.0"
     exon            2176..2737
                     /gene="Arhgap39"
                     /gene_synonym="Porf-2"
                     /inference="alignment:Splign:2.1.0"
     exon            2738..2830
                     /gene="Arhgap39"
                     /gene_synonym="Porf-2"
                     /inference="alignment:Splign:2.1.0"
     exon            2831..2904
                     /gene="Arhgap39"
                     /gene_synonym="Porf-2"
                     /inference="alignment:Splign:2.1.0"
     exon            2905..3104
                     /gene="Arhgap39"
                     /gene_synonym="Porf-2"
                     /inference="alignment:Splign:2.1.0"
     exon            3105..3196
                     /gene="Arhgap39"
                     /gene_synonym="Porf-2"
                     /inference="alignment:Splign:2.1.0"
     exon            3197..3366
                     /gene="Arhgap39"
                     /gene_synonym="Porf-2"
                     /inference="alignment:Splign:2.1.0"
     exon            3367..4612
                     /gene="Arhgap39"
                     /gene_synonym="Porf-2"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cggccgcagc gcactggact agcggcggag acccaggacg tgaagcgctg gctgcggcgg
       61 caacggcggc cgggagccgc cgggagctga ggcgcagcgt gcggtcggtg atgaggggca
      121 gtggcggcgc gccccgctca gggccggctg tgtggcctct tcctgtctga tactggagga
      181 ggcaacctga tggtcctctg acaactgttc acctcagcac tgaggaagca gatggcaatg
      241 tcacagacac aggattatga atgcagaagc caccatgtcg atgagcagga gcctaggatt
      301 cctgggtcga gtaccaggtt ggagtgggtg gagatcattg agccgcgcac gcgcgaacgt
      361 atgtatgcca acctggtcac cggggagtgc gtgtgggacc caccagcggg cgtgcgcatc
      421 aagcgcacca gtgaggacca gtggtgggag ctcttcgacc ccaatacatc acgcttctac
      481 tactacagtg ctgcttcgca gcgcaccgtg tggcatcgcc cacagaactg cgacatcatt
      541 ccgctggcca aactgcagac gctgaaacag aacactgagt ctccgcgtgc ctctgcagac
      601 agcagcccag ggaggggcag tcgagatggt agcacgggct cctcgctgga acccgagcct
      661 gaagaaaggg cacaggagct gccagttcgt ggtgggcggg cgacaacctt ggtcacttcg
      721 aaggaggaga ctagcagttg ttcaccacca ggtgtactcc tggagaagga ctatgaggtg
      781 taccgggatt acagtgctga cggccagctc cttcactaca ggacatcctc tctgcgatgg
      841 aactctggta ataaggaacg catgctcatc aaggttgctg accgcgaacc cagcttcctc
      901 actccccagg gcaatggcta tccagcagac aaccaaccag tggggcatca ccgcagaccg
      961 tctggcagcc agcactcacc taacttgcag acctttgtcc ctgacaatga tggcactgtc
     1021 ttctttccag aaaggcggcc ctcacccttc ctaaggaggg ctgagctctc tggaaactgt
     1081 tcaccattgc tgatacagcc ccgaaagccc tccagtgact cacagccctc ctccccacgc
     1141 tacggttatg aacccccact ctatgaggag cctccagtgg aataccaggc ccccatttat
     1201 gatgaacctc ccatggatgt acagtttgaa cccaacagcc cctaccagac aggctcacca
     1261 cagcggtcac caggccgaaa gccccatcca ttcctgcaag ctaccaaaca gaccccaaca
     1321 tcaccctgcc agcagctgat gcgcaccaag caaaagtgcc ctgagcgttt tctgagcctg
     1381 gaatatagtc ctgtgggcaa agagtacgtg cggcagctgg tgtatgtgga gcaagcaggt
     1441 tccagtccca agcttagagc tgggcccagg cacaagtatg cacccaaccc aggtggtggc
     1501 acctactctc tgcagcccag cccctgcctg ctaagagacc agcgcctggg ggtcaggtca
     1561 ggagactaca gcaccatgga agggcctgag tcacgctcaa gccaaccacc cacaccactg
     1621 ccccaagccc aggaggatgc catgtcctgg tccagtcagc aggataccat gtcttccaca
     1681 ggctactccc caggcactcg taagagaaag aacagaaagc cttctctgtg ccaagtccct
     1741 agcacctcct ccactgacgg tgctggggac ctgctaggag accagcctct gactgaagag
     1801 cgctctccat gcaggtccag ccttacccca gtaaaggctg agaccgacct agtacgaggc
     1861 acacctgagc ccttcctggc acaggcccgg ctggcctggg aggcgcagca agcccacttt
     1921 cacatgaagc agaggggcag ctgggactcc cagcaagatg gctcagggta tgagagtgac
     1981 ggcgctgtcc cactgcccat gcctgggcct gtagtgcgag cattcagtga ggatgaggcg
     2041 ctcgcacagc aggacagcaa gcactggaag cggagcacct ttgaaaagct tggtttccct
     2101 cagatcctgc tggaaaaaag catctctgtg cagaccaacc tggcctcacc ggagccttac
     2161 ctccatccct cacagtctga ggaccttgga gcctgcgccc agtttgagaa cagccggcag
     2221 aaccgcagtg cagtgcccag ctccagctgt gtcttcccca cattcacgct tcgtaagccc
     2281 tcctcagaga cggacatcga gaactgggcc tccaagcact tcaacaagca cacccagggt
     2341 ctcttccggc gaaaggtatc catagccaac atgttggcct ggagcagtga gtccatcaag
     2401 aagcccatga ttgtgactag tgaccggcat gtgaagaagg aggcctgtga gatcttcaag
     2461 ctaatccaga tgtacatggg cgacaggcgg gccaaggcag acccgctgca cgtagcccta
     2521 gagatagcca ccaaaggctg gagtgcacag ggcctacggg atgagctgta tattcagcta
     2581 tgccggcaaa ccacagagaa cttccgccta gagagcctgg cccgtggctg ggagctcatg
     2641 gccatctgcc tggctttctt cccaccaacc cccaagttcc actcctacct agagggctat
     2701 atctaccggc acatggaccc cgttaacgac accaaagtga cacagcacat aaaagagctt
     2761 ctggaaagaa acagtaagaa gaagtccaaa ctgagaaaga aacccaagcc ttatgttgaa
     2821 gagccagatg gggtggcaat aagcacctat gcgaagtact gttaccacaa actacagaag
     2881 gcagccctga ctggggccaa gaagggcctg aagaagccta acgtggagga gatacgacat
     2941 gccaagaacg cagtgttcag cccgtccatg tttggcagtg cactgcagga ggtgatgagc
     3001 atgcagaaag agcgctatcc cgacaggcag ctgccctggg tacagacacg gctctccgag
     3061 gaggtcctgg cactcaacgg tgaccagacg gagggtatct tcagggtccc tggtgacatt
     3121 gatgaggtga atgccctgaa gttgcaggtg gatcagtgga aggtgcctac aggactggag
     3181 gacccccatg tccctgcatc gctgctgaag ctgtggtatc gggagctgga agagcccttg
     3241 attcctcatg aattctacga acaatgcatt gcgcactacg agagcccgga ggctgctgtg
     3301 gccgtggtgc acgcgctacc gcgcatcaac cgaatggtgc tgtgctacct cattcgcttc
     3361 ctccaggtgt tcgtgcagcc agccaatgta gccatcacca aaatggacgt cagcaacctg
     3421 gctatggtga tggcacccaa ctgcctgcgc tgccagtcgg atgatcctcg tgtcatcttc
     3481 gagaatacac gaaaggagat gtccttcctt cgagtgctca ttcagcattt agataccagc
     3541 ttcatggagg gcgtgctata gcacgcgggc tatggactcc tagggtgaca cccggggagg
     3601 tgggagggaa ggccccagcg cgaggcagca tgccaggccc cgccagccgc ccgccctgcc
     3661 ccaggccctc ccgggcaaag cagccacgcc atatctcgtg gccagttcct gtgggtaccg
     3721 gctcgccctg ccggtcgcaa gcaagccagc cccgagaagt gccttctgtt tcccggagcc
     3781 gagcaacact gccctcctgg tcggctgaag cacataccgc gttgctcagg gcaacacgac
     3841 cttgttcccc tcttcagagc aatcctccac caaggcactc gtgccctgat ccctcttacc
     3901 ctagtctagg ggcctctggc tggggcctga aggagaatta gaggtgctct ggagagctgt
     3961 gctggccacc actaggacac aactctgttg acccaatgcc taataggtct ttgtgaaagg
     4021 ggaggcccca aaccaaagcc ctctagggca gggccagggc taggcaggct ttcttgggga
     4081 gggtggggga ggatgagagg ttttgttttg ttttgggggg cttttttttt tttttgagta
     4141 cagaacctat cccataccca gcctacttgt gtataaagat ataaatagaa tgacagatgt
     4201 cagaactaag tttgctaagg acatagtttt aaccagatgc tatttatctc ttgaactgcc
     4261 gtgtggtcct cgcgctgagc aagttagcac caccctcctt tgacctcgcg gcctccgacc
     4321 aaactccact cacaggcggc gcgcggatga gacctgcctg gactggtctg cgttttccat
     4381 tctggaatct gagttcaaac aaattgtcaa acttcatttc tcctgtttat atatatatat
     4441 attttttaga gtttttattt attaaaaaca aaagtcccgc catacggagg cccgcagctc
     4501 tctgggtcag gtcctggacc tctccaggac ctctctggcc gcaggcgctc cctcggacgt
     4561 gtggatcgag gggacagtgc tccgtgtgaa taaagttcaa gtgcacactc gc
//
