LOCUS       NM_198759               4004 bp    mRNA    linear   ROD 01-APR-2024
DEFINITION  Rattus norvegicus Rho GTPase activating protein 27 (Arhgap27),
            mRNA.
ACCESSION   NM_198759 XM_221012
VERSION     NM_198759.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 4004)
  AUTHORS   Sakakibara,T., Nemoto,Y., Nukiwa,T. and Takeshima,H.
  TITLE     Identification and characterization of a novel Rho GTPase
            activating protein implicated in receptor-mediated endocytosis
  JOURNAL   FEBS Lett 566 (1-3), 294-300 (2004)
   PUBMED   15147912
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000010.1.
            
            On Oct 29, 2022 this sequence version replaced NM_198759.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AY394725.1, SRR26643297.36316.1
                                           [ECO:0000332]
            RNAseq introns              :: partial sample support SAMEA5760383,
                                           SAMEA5760386 [ECO:0000350]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-672               JAXUCZ010000010.1  88809821-88810492   c
            673-1092            JAXUCZ010000010.1  88789111-88789530   c
            1093-1275           JAXUCZ010000010.1  88788558-88788740   c
            1276-1356           JAXUCZ010000010.1  88788291-88788371   c
            1357-1440           JAXUCZ010000010.1  88788118-88788201   c
            1441-1508           JAXUCZ010000010.1  88787791-88787858   c
            1509-1599           JAXUCZ010000010.1  88787401-88787491   c
            1600-1704           JAXUCZ010000010.1  88786938-88787042   c
            1705-1803           JAXUCZ010000010.1  88784266-88784364   c
            1804-1909           JAXUCZ010000010.1  88783359-88783464   c
            1910-2032           JAXUCZ010000010.1  88783045-88783167   c
            2033-2131           JAXUCZ010000010.1  88782874-88782972   c
            2132-2209           JAXUCZ010000010.1  88782611-88782688   c
            2210-2344           JAXUCZ010000010.1  88782386-88782520   c
            2345-2450           JAXUCZ010000010.1  88782192-88782297   c
            2451-4004           JAXUCZ010000010.1  88780527-88782080   c
FEATURES             Location/Qualifiers
     source          1..4004
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="10"
                     /map="10q32.1"
     gene            1..4004
                     /gene="Arhgap27"
                     /gene_synonym="Arhgap15; CAMGAP1"
                     /note="Rho GTPase activating protein 27"
                     /db_xref="GeneID:303583"
                     /db_xref="RGD:735202"
     exon            1..672
                     /gene="Arhgap27"
                     /gene_synonym="Arhgap15; CAMGAP1"
                     /inference="alignment:Splign:2.1.0"
     CDS             19..2628
                     /gene="Arhgap27"
                     /gene_synonym="Arhgap15; CAMGAP1"
                     /note="rho-type GTPase-activating protein 27;
                     CIN85-associated multi-domain-containing Rho
                     GTPase-activating protein 1; Rho GTPase activating protein
                     15; CIN85-associated multi-domain containing RhoGAP 1"
                     /codon_start=1
                     /product="rho GTPase-activating protein 27"
                     /protein_id="NP_942054.2"
                     /db_xref="GeneID:303583"
                     /db_xref="RGD:735202"
                     /translation="MAADVEGDVYVLVEHPFEYTGKDGRLIAIQPNERYRLLRRSTEH
                     WWHVRREPGGRPFYLPAQYVRELPALGDPVPAPQPSVLQQRPAVPEPLAYDYRFVSTP
                     VGADGSSAEPRGRASSLCGPARQRTSGQRNSLAPGGPACLYLRPAAPVRPAQSLDDLA
                     RGGTAPPAGLLGSAGHFKASSVAGSWVCPRPLARSDSENVYEAIPDLRCPPRAKSPKQ
                     VDEPPEPVYANVERQPQVTSPRSAAAPPRLSPVWETHTDAGTGRPYYYNPDTGVTTWE
                     SPFEAPEGATSPTTSRASVGSGESLETEWGQYWDEESGRVFFYNPLTGETVWEDETEE
                     LEDDPEEQLEMQPSLSPRSPGQQRPPTPETDYPELLTSYPEEDYSPVGSFSDLGPTSP
                     LVAPPGWSCQITPEKQMLYTNQFTQEQWVRLEDQEGKPYFYNPEDSSVQWELPQVPVP
                     APRSGRKSSQDSDTPAQASPPEEKIKTLDKAGVLHRTKTVDKGKRLRKKHWNASWTVL
                     EGGVLTFFKDSKTSAASGLRQPSKLSTPEYTVELRGASLSWAPKDKSSKKNVLELRSR
                     DGSEYLIQHDSEAIISTWHKAIAEGIEELSADLPQREEGEPSSADFGSSERLGSWKEE
                     DVRPNAASPSLNPGSQESDLSRVRHKLRKFLQRRPTLQSLREKGYIKDQVFGCALAQL
                     CERERSPVPRFVQQCIRTVEARGLDIDGLYRISGNLATIQKLRYKVDHDERLDLDDGR
                     WEDVHVITGALKLFFRELPEPLFPFSHFHQFIAAIKLQDPAQRSRCVRDLVRTLPAPN
                     HDTLRLLIQHLCRVIEHGEQNRMSVQNVAIVFGPTLLRPEMEEASMPMTMVFQNQVVE
                     LILHQCADIFPPH"
     exon            673..1092
                     /gene="Arhgap27"
                     /gene_synonym="Arhgap15; CAMGAP1"
                     /inference="alignment:Splign:2.1.0"
     exon            1093..1275
                     /gene="Arhgap27"
                     /gene_synonym="Arhgap15; CAMGAP1"
                     /inference="alignment:Splign:2.1.0"
     exon            1276..1356
                     /gene="Arhgap27"
                     /gene_synonym="Arhgap15; CAMGAP1"
                     /inference="alignment:Splign:2.1.0"
     exon            1357..1440
                     /gene="Arhgap27"
                     /gene_synonym="Arhgap15; CAMGAP1"
                     /inference="alignment:Splign:2.1.0"
     exon            1441..1508
                     /gene="Arhgap27"
                     /gene_synonym="Arhgap15; CAMGAP1"
                     /inference="alignment:Splign:2.1.0"
     exon            1509..1599
                     /gene="Arhgap27"
                     /gene_synonym="Arhgap15; CAMGAP1"
                     /inference="alignment:Splign:2.1.0"
     exon            1600..1704
                     /gene="Arhgap27"
                     /gene_synonym="Arhgap15; CAMGAP1"
                     /inference="alignment:Splign:2.1.0"
     exon            1705..1803
                     /gene="Arhgap27"
                     /gene_synonym="Arhgap15; CAMGAP1"
                     /inference="alignment:Splign:2.1.0"
     exon            1804..1909
                     /gene="Arhgap27"
                     /gene_synonym="Arhgap15; CAMGAP1"
                     /inference="alignment:Splign:2.1.0"
     exon            1910..2032
                     /gene="Arhgap27"
                     /gene_synonym="Arhgap15; CAMGAP1"
                     /inference="alignment:Splign:2.1.0"
     exon            2033..2131
                     /gene="Arhgap27"
                     /gene_synonym="Arhgap15; CAMGAP1"
                     /inference="alignment:Splign:2.1.0"
     exon            2132..2209
                     /gene="Arhgap27"
                     /gene_synonym="Arhgap15; CAMGAP1"
                     /inference="alignment:Splign:2.1.0"
     exon            2210..2344
                     /gene="Arhgap27"
                     /gene_synonym="Arhgap15; CAMGAP1"
                     /inference="alignment:Splign:2.1.0"
     exon            2345..2450
                     /gene="Arhgap27"
                     /gene_synonym="Arhgap15; CAMGAP1"
                     /inference="alignment:Splign:2.1.0"
     exon            2451..4004
                     /gene="Arhgap27"
                     /gene_synonym="Arhgap15; CAMGAP1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gagagcgcgg tggccgcgat ggcggcggac gtcgaggggg acgtgtacgt gctggtggag
       61 caccccttcg agtacaccgg caaagacggg cgccttatcg ccatccaacc caatgagcgt
      121 taccgactgc tgcgccgcag caccgagcac tggtggcacg tgcggcggga gcctgggggt
      181 cgccccttct acctcccggc tcagtacgta cgcgagctgc cggcgctcgg tgaccctgtc
      241 ccggccccgc agccttccgt actgcagcag cgccccgcag tcccggagcc tctggcctac
      301 gactaccgct tcgtgagcac cccggtgggt gccgatgggt cttctgccga gccccggggc
      361 cgtgccagct ccctgtgtgg ccctgcacga caacgcacca gtggccagcg caacagcctg
      421 gctccgggag ggcccgcctg cctgtacctg cggcccgcag cgccggtgcg acccgcgcag
      481 tccctggatg acttggcgcg cggcggcacc gcgccccctg ccggcctcct cggcagcgcg
      541 ggccacttca aggcctccag cgtggcgggc tcctgggttt gtccccggcc cctggcgcgt
      601 agcgactcgg agaatgtcta cgaggctatc ccggacttgc gctgtcctcc gcgggcgaag
      661 agcccaaaac aggtagacga gccaccggaa ccagtgtatg ccaacgtaga gaggcaacct
      721 caggtcacgt cgccgcgctc tgctgcagct cctcctcggc tcagcccggt gtgggagacg
      781 cacacagatg cgggcactgg gcgcccctac tactacaacc ccgacacggg cgtgaccacc
      841 tgggagtcac cctttgaagc acctgaaggc gccaccagcc cgactacctc ccgggcctct
      901 gtgggcagcg gggagagcct ggagacagag tggggccagt actgggatga ggagagcggc
      961 agggtgttct tctacaaccc cttgacgggt gagacggtct gggaggacga gactgaggag
     1021 ctggaggacg atcccgagga acaactggag atgcaaccca gcctgagccc gcgaagcccg
     1081 gggcagcaga ggcccccgac tcctgaaaca gactaccctg aattactgac cagttatcct
     1141 gaagaggact attctcctgt gggctccttc agtgatctcg gcccaacttc tcccttggtt
     1201 gcaccccctg gctggtcctg tcaaattacc ccagagaagc agatgctcta caccaaccag
     1261 ttcactcaag agcagtgggt aaggttggag gaccaggaag ggaagccata tttctacaat
     1321 ccagaggact cctctgttca gtgggaactg ccccaggtcc cggtccctgc ccctcggagt
     1381 ggtcgtaaat ccagccagga tagtgatact ccagcccagg ctagccctcc agaggagaag
     1441 atcaagaccc tggacaaggc aggagtgctc catcgaacca agacagtaga caaggggaag
     1501 agacttcgga agaaacactg gaatgcttcc tggaccgtgc tggagggcgg tgtcctgacc
     1561 ttcttcaagg attcaaagac ctcagctgca agcggcctga ggcagccttc caaactctcc
     1621 acccctgaat atacagtcga actgaggggg gcctcgctct cgtgggcccc caaagacaaa
     1681 tccagcaaga agaatgtgct agagctccgg agccgagatg gctcagagta cctgatccag
     1741 catgactcag aggccatcat cagcacctgg cacaaggcca ttgccgaagg catcgaggag
     1801 ctgtctgcag acctgcccca aagggaggaa ggtgaaccca gcagtgctga ttttgggtcc
     1861 agtgagcgcc tcggaagctg gaaggaggag gatgtgcggc cgaatgcagc ctcaccctcg
     1921 ctcaaccccg gaagccagga aagcgacttg agcagggtcc ggcacaagct ccgcaaattc
     1981 ctacagagac gacccactct gcagtctttg cgggagaagg gctacatcaa agaccaggtg
     2041 tttggatgtg cactggctca actgtgcgag cgcgagagga gccctgtgcc acgcttcgtg
     2101 cagcaatgca tccgcaccgt cgaggcccgg gggctggata ttgatgggct gtaccgcatc
     2161 agtgggaacc tggccaccat ccagaagctg cgctataagg tggatcacga tgaacgcttg
     2221 gacctggacg atgggcgctg ggaagacgtc cacgtgatca caggtgccct gaagctcttc
     2281 ttccgagagc tgccggaacc cctcttcccc ttctcgcact tccaccagtt catagcagcc
     2341 atcaagctgc aagacccggc ccagcgcagc cgctgtgtgc gtgacctggt gcgtacgcta
     2401 ccagccccca accacgacac tctccgcctg ctcatccagc atctgtgtcg ggtgatcgag
     2461 catggcgagc agaaccgtat gtctgtgcag aatgtggcca tagtgttcgg gcccacgctg
     2521 ctgaggcctg agatggagga agccagcatg cccatgacca tggtgttcca gaaccaggtg
     2581 gtagagctca tcctacatca gtgcgcagac atcttcccac cgcactgact ctggaccctg
     2641 ggttagctgg aggccgcgag gctggacttc ctctgaggct ctccacttcc caccccgctg
     2701 cactgtgact tcaacacccc ctcgattcag agggtacggt gacccctggt gggtagttca
     2761 tgaaatgtga tttctccctg tcacatcccc tgtaggtgtt cattagggcc ctttcccgat
     2821 tacaactccg cctattgcgt ggatgtgata atgtccctgg ggctgggagg tgaatgtttg
     2881 ttttagagtc ccatccaccc gcccaccccg gctgaaagaa gggatttggt gagagccttc
     2941 tggtgtcctc aggcctgcac ctggccaggc cttggagacc ctgtaggccc cgtgctatgc
     3001 aagaggtcat gaagcagcta ctgacgtcat ctctgctgcc aggaagggga ctgaccctgg
     3061 ctgccagccc aggccactga ctgctttcct cagccttcca ctccagtgtc accctgacac
     3121 atgccacctg agaacttttc ctatgcttcc ctctctccct gggccacacc cgttctccac
     3181 aggagttctt catactaacc ccatgccaaa cctgcaccta ctccacatgg ctcctgggat
     3241 ctgggacttg cagaagtcga attacttcag gggtccatag gtgatccggt tcccggcaaa
     3301 ggctctcccc acagcaagcc cagcttctag aggaggaagt gatccctcaa cccccagcag
     3361 cacagcctat aggtggacca gagtaaatct gcaggagcac tttgtgtagg ttagaggttg
     3421 ggggaccctg aaggcagcag ggaacctacc acagctggtt ttttggggag ggacagcata
     3481 aatagaagcc cccagctgct gtctgtaccc tggctggatg cctacctggt acccacttgc
     3541 cacgcagagc taggagaggc ctgtccggaa ggtctcagcc ttaggcaaac agttgaacct
     3601 gtgtctgctg cccgcttcct ccctcatgca cacaccacct cagtttatgg gtctgaaccc
     3661 ctagctccac cccccgcccc acccccactg actcaacaaa caataatagc taatatttat
     3721 taaacattcg tactatgcca gtctttccct tgggtttctc ccttggttcc atgcagtcca
     3781 tatttattgt gggtcctcac gtgccgggca ctgcgctctg gggtagaggt tctgcgcatg
     3841 cgttctggag cttgacaccc agttagtacg gctgatgcga gcccagccct gaccgtggca
     3901 gggcgcagaa gagaacgagt ggaggcctct tgctgtacac ctatatattt aaagtcccaa
     3961 ggcaagcgaa taactaactg ttaaataaaa tgtttattct ccta
//
